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Kimberly Oakeson Biology 1010 Kathleen Staker 4/18/2011 Stress Hormones: Epinephrine and Cortisol Stress has been a negative factor in my life for the past few years. After I heard of the opportunity to research anything in biology, I immediately thought of stress because I thought it would be interesting to learn what causes it and possibly some treatments. I found that it is estimated that about 90% of doctor visits are due to stress (Scott, Chronic Stress). This is alarming but not unbelievable because of our modern fast-paced society. The primary hormones that produce stress are epinephrine and cortisol which are secreted from the top of the kidneys. These two stress hormones can be good, but if they are secreted excessively, it can cause minor and major health problems. Walter Cannon, a renowned Harvard Medical School Physiologist, discovered the “fright, fight, or flight response” which was the first scientific explanation of how a mental state could control what was considered an automatic physical response (Mind/Body Medicine). Today, the phrase is more commonly known as the “fight-or-flight” response. During this response, epinephrine and cortisol are released into the bloodstream which usually causes to heart to pump faster, blood pressure to rise, and the blood vessels to narrow so that blood can flow to the major muscle groups. Epinephrine isn’t a common word and was unknown to me until I realized that it is the same thing as adrenaline. Adrenaline causes the brain to become more aware and is used in high-stress situations. I thought it most interesting that the EpiPen, a shot used to reduce the effects of cardiac arrest, anaphylactic reactions, and asthma, is a dose of epinephrine. In cardiac arrest, epinephrine allows cardiac action, which increases the chance of survival. Epinephrine allows vasoconstriction, thus increasing blood pressure, so that the victim is able to receive blood to their major organs and muscles. It is also acts as a bronchodilator, which widens the airways of the lungs. This helps asthma patients to relieve their wheezing and dyspnea (Epipen). Doctors may prescribe EpiPens to patients who don’t even know they’re allergic to anything (Epipen (epinephrine) Injection). It is the best to be cautious, just in case an anaphylactic reaction occurs. Most people connect stress with anxiety, but there are actually different types of stress. Eustress is fun and exciting. It is the kind of stress that is exerted when someone races a go-kart or fourwheeler. It gives you what is widely known as the adrenaline rush. Acute stress is the normal stress that most people face in their daily lives. It’s short-term and is counteracted by the relax response. Episodic stress is when stress becomes a way of life and people make out small situations to be more than they should be. These types of people are quite often called “drama queens”. Chronic stress is long-term and can cause many health problems (Scott, Chronic Stress). Chronic stress effects are numerous and quite common in our world today. These health issues are subject to but not limited to depression, diabetes, hair loss, heart disease, hyperthyroidism, obesity, obsessive compulsive, anxiety disorders, tooth and gum disease, ulcers, and cancer. This is boggling to my mind that two hormones can cause such destruction in a body. The most surprising health affect to me is hyperthyroidism. Hyperthyroidism is when the thyroid over-exerts itself and produces too much thyroid hormone (Scott, Chronic Stress). It is the primary cause of Graves disease, which has countless effects such as restlessness, nervousness, weight loss, and tremors (Graves Disease). There are quite a few ways to offset the effects of stress. This includes stress management, including counseling, meditation, yoga, and deep-breathing techniques, and exercise (Scott, Stress and Health). The most interesting prevention that I thought was exercise. I found that exercise burns off extra adrenaline, thus loosening muscles and making the body more relaxed. It also increases the oxygen flow in the blood, which balances the hormone level. By doing these activities, the brain receives a relax signal, which then produces the relax response. This is when the body returns to its normal functions and epinephrine and cortisol levels aren’t as high as before. Everyone has experienced stress, whether it is in high doses or low doses. Chronic stress is common because of the fast-paced society we live in. This causes more doctor visits and more diseases and illnesses. Epinephrine and cortisol are the reason why stress is in so many lives. When there are physical, emotional or psychological strains, these hormones increase their production. Learning about these stress hormones was beneficial to me. I am now more knowledgeable in ways to reduce stress so that I can lead a healthier and stress-free life. Bibliography Adrenaline. n.d. 2011 <http://www.causeof.org/adrenal.htm#WhatIs>. Adrenergic Drugs I. n.d. 2011 <http://www.elmhurst.edu/~chm/vchembook/663adrenergic.html>. Epipen. 6 July 2009. 2011 <http://www.rxlist.com/epipen-drug.htm>. Epipen (epinephrine) Injection. February 2008. 2011 <http://dailymed.nlm.nih.gov/dailymed/archives/fdaDrugInfo.cfm?archiveid=7150>. Graves Disease. April 2010. A.D.A.M. 2011 <http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001398/>. Kozarovich, Lisa Hurt. Stress: A Cause of Cancer? April 2011. April 2011 <http://stress.about.com/gi/o.htm?zi=1/XJ&zTi=1&sdn=stress&cdn=health&tm=262&gps=90_1 077_1419_726&f=11&su=p1051.2.336.ip_&tt=2&bt=0&bts=1&zu=http%3A//psychcentral.com/l ibrary/stress_cancer.htm>. "Mind/Body Medicine." Harvard Health Publications (2002). Scott, Elizabeth. Chronic Stress. 22 December 2007. 2011 <http://stress.about.com/od/stressmanagementglossary/g/Chronicstress.htm>. Stress and Health. 4 May 2009. 2011 <http://stress.about.com/od/stresshealth/a/stresshealth.htm>. The Definition Of Epinephrine. 22 December 2007. 2011 <http://stress.about.com/od/stressmanagementglossary/g/Epinephrine.htm>. The Definition Of Relaxation Response. 10 December 2005. 2011 <http://stress.about.com/od/stressmanagementglossary/g/relaxationresp.htm>.