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Asymmetric Beta, Sleep Spindles and Vertex Waves; Encephalomalacia Caused by Acute Viral Meningoencephalitis in Newborn. A 12-year-old with mild
cognitive impairment, left hemiparesis, and intractable epilepsy due to extensive involvement of the right frontal-parietal-temporal, insula, and thalamic
regions caused by acute viral encephalitis at the age of 2 weeks. EEG during sleep shows marked suppression of spindles over the right hemisphere.
Sleep spindles are generated in the reticular nucleus of the thalamus, and through thalamocortical neurons the cortex is triggered to generate spindle
bursts.21 Extended cortical areas in the centroparietal regions (pyramidal neurons), most likely the whole parietal cortex and the posterior part of the frontal
cortex, are involved
in the Nonepileptoform
generation of sleep
spindles
recordedEEG
using the MEG.22 Lesions in the thalamocortical circuit, especially thalamus and
Source: Focal
Activity,
Atlas as
of Pediatric
parietal lobe, can attenuate the sleep spindles.5,23,24
Citation: Laoprasert P. Atlas of Pediatric EEG; 2011 Available at: http://mhmedical.com/ Accessed: May 11, 2017
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