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Squamous Cell
Carcinoma
Amber Cadd and Kaylee Kwan
Definition/Description
Squamous Cell Carcinoma:
● Form of skin cancer
● Slow-growing fatal tumor of
squamous epithelium.
● Usually found in the lungs and
skin and occurring also in the
anus, cervix, nose, mouth, and
bladder.
➔ Crusted, Slightly raised
➔ Red, white or red/white
Pathophysiology
http://emedicine.medscape.com/article/1965430-overview#a3
3 histologic grades
Well differentiated: Characterized by more normal-appearing nuclei with abundant cytoplasm and
extracellular keratin pearls
Moderately differentiated: Exhibits features intermediate between well-differentiated and poorly
differentiated lesions
Poorly differentiated: Shows a high degree of nuclear atypia with frequent mitoses, a greater nuclearcytoplasmic ratio, and less keratinization; it may be difficult to distinguish from mesenchymal
tumors, melanoma, or lymphoma
Symptoms
Signs to check if you have squamous cell carcinoma:
➔A bump or lump on the skin
◆ Can feel rough
◆ May become dome-shaped or crusty and can bleed
➔A sore that does not heal or heals, and returns
➔Flat, reddish scaly patch that grows slowly
➔Flat sore with scaly crust
➔A new sore or raised area on an old scar or ulcer
➔A rough, scaly patch on your lip that may evolve to an open sore
➔A red sore or rough patch inside your mouth
➔A red, raised patch or wart-like sore on or in the anus or on your genitals
Causes
Ultraviolet (UV light) exposure over a lifetime.
Daily year-round exposure to the sun’s UV light
Especially in summer
Tanning beds
Risk Factors
That Can Increase Your Skin Cancer Risks:
● Increases as you age
● Conditions that weaken an immune system
● Being a male- 2x more likely compared to women
● Fair skin
○ Blonde/Red Hair
○ Blue/Green Eyes
○ Skin/Freckles That Burns Easily
Tests + Diagnosis
Physical Exam
Examine skin for signs
Removing A Sample Of Tissue For Testing
Removal of suspicious looking skin.
Treatments/Drugs
Some May Include The Following:
Laser Therapy
Freezing
Photodynamic Therapy
Medicated Creams/Lotions
Radiation Therapy
Lifestyle + Home Remedies
Diet
Apple cider vinegar
Cesium Chloride
Iodine
Eggplant extract cream
Alternative Medicine
High Potency Multivitamin
Fish Oil
Vitamin C
Vitamin E
Selenium
Support
Cancer Treatments Centers of America- cancercenter.com
Coolibar- coolibar.com
ACMS (American College of Mohs Surgery)- mohscollege.org
Dermatologist El Paso, TX. Welcome to Cheryl A Kosarek, MD, FAADkosarekmd.com
Dermatology & Aesthetic Center of El Paso- dermatologyelpaso.com
Mayo Clinic- mayoclinic.org
Preventions
Wear sunscreen all year-round
Even in the winter months and cloudy days
Avoid the sun during the heat of the day
AKA: The middle of the day
Wear protective clothing
Avoid tanning beds
Do self-checks and
Report to your doctor of suspicious looking skin spots
Citations (APA)
(n.d.). Retrieved December 2, 2015, from http://medicaldictionary.thefreedictionary.com/squamous cell carcinoma
Skin Cancer Foundation. (n.d.). Retrieved December 2, 2015, from
http://www.skincancer.org/skin-cancer-information/squamous-cell-carcinoma
Squamous cell skin cancer: MedlinePlus Medical Encyclopedia. (n.d.). Retrieved December 2,
2015, from https://www.nlm.nih.gov/medlineplus/ency/article/000829.htm
Skin cancer risk factors. (1). Retrieved December 7, 2015, from
http://www.cancercenter.com/skin-cancer/risk-factors/
Cutaneous Squamous Cell Carcinoma. (n.d.). Retrieved December 7, 2015, from
http://emedicine.medscape.com/article/1965430-overview#a3