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Handout 1: Domestication and Disease Instructions: Read the column on the left and answer the questions posed in the space provided using the Concept map on the overhead. The year is 4000BCE and animal domestication has begun. You live in the deserts of the Middle East where it can get very cold in winter and during other seasonal evenings. Sand storms can kill crops and animals alike if left unprotected. Q1: How do you protect yourself and your livestock from harm? Q2: How do you keep warm inside your home if wood is a rare commodity? Agriculture has begun. Plants are grown in one place year after year. Q3: How do you prevent the soil from losing its nutrients? Q4: Where is water coming from to irrigate the plants? Q5: Where does human waste go to? Q6: Where are crops stored? Q7: Are storage areas impenetrable? Q8: What invades them? Unknown to the humans in this new world of domesticated life and growing sophistication, a new enemy is lurking. It is invisible to the naked eye and potentially deadly. It is the infectious disease. Before domestication, nomadic people continually moved in search of food by following herds of large game and did not live closely to large herds of animals for long periods of time. Q9: Why did infectious disease not exist during nomadic times?