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Vaginal discharge - Vaginitis Trichomoniasis, bacterial vaginosis, candidiasis Recommend See “How to do an STI check”, page 466 Treat for chlamydia/gonorrhoea if unsure and offer STI tests as part of your assessment Background The cause of vaginal discharge can be difficult to diagnose on clinical examination Related topics: Vaginal discharge – cervicitis, page 476 Low abdominal pain in female – possible PID, page 484 1. May present with: Trichomonas is an STI that may present with: Positive test result Inflammation of the vulva and vaginal walls which may cause soreness or itching White or green vaginal discharge which is typically ‘frothy’ and has a ‘fishy’ odour Prelabour rupture of membranes and preterm delivery Bacterial vaginosis (BV) (includes organisms such as gardnerella) is not sexually transmitted but is caused by an overgrowth of bacteria and may present with: Laboratory report from the high vaginal swab notes the presence of ‘clue cells’ (Asymptomatic infection) Vaginal discharge that is typically thin, white or grey and has a ‘fishy’ odour (similar to trichomonas but not frothy and vaginal walls are not inflamed) Miscarriage, pre-labour rupture of membranes, preterm delivery Candidiasis (thrush) is not sexually transmitted but is caused by an overgrowth of yeast and may present with: Inflammation (redness, swelling) of the vulva or vagina causing itch or soreness Vaginal discharge is typically white, and sticks to the vaginal walls (curd like) Cracks or fissures in the skin folds (genital herpes must be excluded, see Genital sores / ulcers If found on a vaginal swab and the woman does not have symptoms – treatment is not required Candidiasis is common in healthy women, but can also overgrow as a result of high oestrogen (pregnancy), high sugar (uncontrolled diabetes), immune suppression (HIV) or after taking some antibiotics. 2. Immediate management: not applicable 3. Clinical assessment: See How to do an STI check History Examination if the woman complains of low abdominal pain or experiences pain during the examination assess for PID. See Low abdominal pain in female – possible PID Testing: if the client presents with repeated episodes of vaginal thrush do a BGL and assess for risk of HIV urinalysis: if nitrites are positive send mid stream urine for MC&S. See UTI (Adult) urine pregnancy test is indicated for all women of childbearing age (12-52 years) offer blood test for syphilis, HIV, hepatitis C and hepatitis B if not immune See Hepatitis and HIV Infection If able to do a speculum examination take the following swabs endocervical swab for gonorrhoea and chlamydia PCR and MC&S and high vaginal swab for trichomonas PCR and for MC&S pap smear (+ Thin Prep) if due. See Pap smear If unable to do a speculum examination take the following self collected low vaginal swab for gonorrhoea and chlamydia PCR, for trichomonas PCR and for MC&S If unable to do a speculum examination or self collected swabs first catch urine for gonorrhoea, chlamydia and trichomonas PCR 4. Management: See How to do an STI check Education Give information about trichomonas, BV and candida as appropriate Trichomoniasis is an STI but one that may persist in women for years Discuss safe sex and provide condoms as appropriate Medication Management Treat for trichomonas if Vaginal discharge is typical of trichomoniasis Trichomonas is detected on a swab, urine specimen or Pap smear Treat for bacterial vaginosis if Vaginal discharge is typical of BV High vaginal swab is suggestive of BV and the woman is pregnant or has symptoms Treatment for trichomonas and bacterial vaginosis is the same; if not allergic treat with Metronidazole (can be used if pregnant or breastfeeding) DTP IHW / RIN / SRH / NP / IPAP Authorised Indigenous Health Workers and Isolated Practice Area Paramedic must consult MO Rural and Isolated Practice/Sexual and Reproductive Health Program Endorsed Registered Nurses may proceed Nurse Practitioners may proceed Form Strength Route of Administration Recommended Dosage Duration Tablet 200mg; 400mg Oral 2 gram 1 dose Treatment with Metronidazole in the 1st trimester is contraindicated and in the 2nd and 3rd trimester should be restricted to treatment for symptomatic disease Provide Consumer Medicine Information if available: Avoid alcohol while and for 48hrs after taking this drug Management of Associated Emergency: Consult MO Schedule 4 Metronidazole Or Tinidazole (not if pregnant or breastfeeding) DTP IHW / RIN / SRH / NP / IPAP Authorised Indigenous Health Workers and Isolated Practice Area Paramedic must consult MO Rural and Isolated Practice/Sexual and Reproductive Health Program Endorsed Registered Nurses may proceed Nurse Practitioners may proceed Route of Form Strength Recommended Dosage Duration Administration Tablet 500mg Oral 2 gram 1 dose Provide Consumer Medicine Information if available: Avoid alcohol while and for 48hrs after taking this drug Management of Associated Emergency: Schedule 4 Tinidazole If recurrent bacterial vaginosis consult MO as the woman may need a course, rather than a single dose, of Metronidazole. DTP IHW / RIN / SRH / NP / IPAP Authorised Indigenous Health Workers and Isolated Practice Area Paramedic must consult MO Rural and Isolated Practice/Sexual and Reproductive Health Program Endorsed Registered Nurses may proceed Nurse Practitioners may proceed Form Strength Route of Administration Recommended Dosage Duration Tablet 200mg; 400mg Oral 400 mg bd 7 days Treatment with Metronidazole in the 1st trimester is contraindicated and in the 2nd and 3rd trimester should be restricted to treatment for symptomatic disease Provide Consumer Medicine Information if available: Avoid alcohol while and for 48hrs after taking this drug. Management of Associated Emergency: Consult MO Schedule 4 Metronidazole Treat for candidiasis if: Inflammation or discharge is typical of candidiasis Candida is detected on a vaginal swab and symptoms are present Ask about allergy to anti-yeast/anti-fungal preparations Schedule 3 Clotrimazole Vaginal Cream DTP IHW / SRH / NP / IPAP Authorised Indigenous Health Workers and Isolated Practice Area Paramedic must consult MO Sexual and Reproductive Health Program Endorsed Registered Nurses may proceed Nurse Practitioners may proceed Route of Form Strength Recommended Dosage Administration Cream, Cream 1% For vaginal use Use once daily, preferably in the evening for 6 35g tube successive days, 1 applicator should be filled with cream and inserted as deeply as possible into the vagina with the client lying on her back. Provide Consumer Medicine Information if available: Management of Associated Emergency As for severe allergic reaction see Duration 6 days Contact Tracing: Contacts - Trichomonas: Treat regular male partners. Men are usually asymptomatic but should have an STI check and be treated with either Metronidazole or Tinidazole Women may remain infected with trichomonas for months or years. It is important that women and their partners understand that detecting trichomonas on a swab or Pap smear may not necessarily indicate that it has been recently acquired Contacts of women with BV and candidiasis do not need to be treated 5. Follow up: Follow up at 1 week and at 2-3 months is important. See How to do an STI check 6. Referral /Consultation: Consult MO if pregnant or if symptoms are recurrent or severe.