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Using Light to Control Drug Release Work from the Friedman Lab at the UMKC School of Pharmacy Aim: Eliminate most insulin injections, improve blood sugar control. • Drug (Insulin) linked to polymer with light cleavable linker. • Material injected under the skin, irradiated in response to blood sugar cues. www.friedmanlaboratory.org A Light Activated Insulin Depot Described as “Truly Innovative” and “A Paradigm Shift” by reviewer. Featured on frontispiece of Angewandte Chemie (~14 impact factor). Reported by AP in multiple sites. Covered by KSHB NBC affiliate. Worldwide Insulin market over lifetime of patent: ~ $0.5 trillion www.friedmanlaboratory.org