Download Powerpoint - Circulation Research

Survey
yes no Was this document useful for you?
   Thank you for your participation!

* Your assessment is very important for improving the work of artificial intelligence, which forms the content of this project

page
1
page
2
page
3
page
4
page
5
page
6
page
7
page
8
page
9
Document related concepts
no text concepts found
Transcript 
Disruption of Planar Cell Polarity Signaling Results in
Congenital Heart Defects and Cardiomyopathy Attributable
to Early Cardiomyocyte Disorganization
by Helen M. Phillips, Hong Jun Rhee, Jennifer N. Murdoch, Victoria Hildreth,
Jonathan D. Peat, Robert H. Anderson, Andrew J. Copp, Bill Chaudhry, and Deborah
J. Henderson
Circulation Research
Volume 101(2):137-145
July 20, 2007
Copyright © American Heart Association, Inc. All rights reserved.
Figure 1. Abnormalities in organization of cardiomyocytes in the early heart tube.
Helen M. Phillips et al. Circ Res. 2007;101:137-145
Copyright © American Heart Association, Inc. All rights reserved.
Figure 2. Defects in cardiac looping in Crc mutants.
Helen M. Phillips et al. Circ Res. 2007;101:137-145
Copyright © American Heart Association, Inc. All rights reserved.
Figure 3. Scrib plays roles in chamber expansion and stabilization of pharyngeal arch arteries.
Helen M. Phillips et al. Circ Res. 2007;101:137-145
Copyright © American Heart Association, Inc. All rights reserved.
Figure 4. Abnormalities in the ventricular and outflow tract myocardium in Crc/Crc.
Helen M. Phillips et al. Circ Res. 2007;101:137-145
Copyright © American Heart Association, Inc. All rights reserved.
Figure 5. Cardiac septation and alignment defects in Crc.
Helen M. Phillips et al. Circ Res. 2007;101:137-145
Copyright © American Heart Association, Inc. All rights reserved.
Figure 6. Crc/Crc cardiomyocytes largely recover from early abnormalities.
Helen M. Phillips et al. Circ Res. 2007;101:137-145
Copyright © American Heart Association, Inc. All rights reserved.
Figure 7. Scrib and Vangl2 colocalize in ventricular cardiomyocytes.
Helen M. Phillips et al. Circ Res. 2007;101:137-145
Copyright © American Heart Association, Inc. All rights reserved.
Figure 8. Cardiovascular defects in Lp/+, Crc/+ fetuses.
Helen M. Phillips et al. Circ Res. 2007;101:137-145
Copyright © American Heart Association, Inc. All rights reserved.
Related documents