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Anatomy and Physiology I – Fall 2014
Cells – Part 1
Chapter 3.1 (Parts of a Cell), 3.2 (The Plasma Membrane), 3.4 (Cytoplasm – The Cytosol,
Centrosome, Cilia, and Flagella sections)
1.
Selective permeability
2.
Phospholipid bilayer
3.
Fluid Mosaic Model
4.
Receptor and Ligand
5.
Cytosol versus Cytoplasm
6.
Cytoskeleton
a.
Microfilaments
b.
Intermediate filaments
c.
Microtubules
7.
Microvilli
8.
Centrioles
9.
Cilia
10.
Flagella
1
Cells come in a wide range of:
 Sizes
• Shapes
• Functions
For cells and cell components – Structure Determines Function
Cell Theory
1.
Building blocks of living organisms
2.
Smallest units that perform all vital functions
3.
Maintain cellular homeostasis
4.
Come from division of preexisting cells
CELL STRUCTURE
Basic Regions of the Cell (See Fig. 3.1)
1. Plasma membrane 2. Cytoplasm with organelles 3. Nucleus
2
I.
Plasma Membrane (Fig. 3.2) View Animation: Membrane
functions – Sections 2.1, 2.2, 2.3, and 2.5 (Skip Fig. 3.3)
A. Functions
1.
Isolation of material inside cell from outside cell
B.
2.
Selective permeability
3.
Senses and reacts to environment
4.
Allows connections between cells and connections of
cells with their surroundings
Fluid Mosaic Model
http://www.youtube.com/watch?v=Qqsf_UJcfBc
C.
Structure of the Plasma Membrane
3
1.
Phospholipid bilayer
Tails and Heads OR ‘to fear or not to fear, that is the question’
2.
Proteins (Fig. 3.3) Answer question beneath figure
a.
Peripheral proteins
b.
Integral membrane proteins
1.
Cellular adhesion molecules
Disease: Metastasis of cancer
b.
Recognition proteins
4
Disease: Transplant rejection
c.
Receptor proteins and ligands
Disease – Type II diabetes
d.
Carrier proteins and channels
Diseases:
1.
Cystic fibrosis
5
2.
3.
Long-QT syndrome
Cholesterol – lipid vital to keeping membrane fluid
SKIP “Gradients Across Plasma Membrane” section
II.
Cytoplasm – material between plasma membrane and nucleus.
Contains a) fluid, b) cytoskeleton, c) organelles, d) inclusions
A.
Cytosol - fluid portion of cytoplasm
B.
Cytoskeleton (Fig. 3.15) Answer question beneath figure
1.
Functions
a.
Supportive framework
b.
Gives cell shape
c.
Movement of cell and materials within cell
d.
Anchoring of material within cell
e.
Form parts of cilia, centrioles, flagella, and
spindle apparatus during mitosis
2.
Structure - composed of several types of supports:
a.
Microfilaments
Structure –
b.
Intermediate filaments
Structure 6
c.
B.
Microtubules
Structure –
Microvilli
Structure -
Location -
Function Disease – celiac disease
7
C.
Centrioles (Fig. 3.16) Answer question beneath figure
Structure –
Function –
Not found in nondividing cells
http://www.youtube.com/watch?v=JMAg_PwSMjA
D.
Cilia (Fig. 3.17) Answer question beneath figure
Structure –
Location -
Function -
8
Disease: Respiratory infections due to smoking
E.
Flagella
Structure –
Location –
Function -
http://www.youtube.com/watch?v=IEdb3wTMSBo
9
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