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Abstract Submission Template for Poster Presenters Use example below (word limit is 250 words) Whole Cell Impedance Analysis for Metastatic and Non-Metastatic Cancer Cells H.S. Kim1, Y.H. Cho1, A.B. Frazier2, G. Chen3, D. Shin3, and A. Han1 Electrical and Computer Engineering, Texas A&M University, USA 2School of Electrical and Computer Engineering, Georgia Institute of Technology, USA 3Winship Cancer Institute, Emory University, USA 1Dept. Quantifying heterogeneous tumor cell populations has been one of the major challenges in understanding tumorigenesis and improving cancer therapy. We have developed a whole cell electrical impedance spectroscopy microsystem and utilized it for analyzing metastatic and non-metastatic head and neck cancer (HNC) cell lines. The device successfully differentiated two different HNC cell lines, the non-metastatic 686LN and the metastatic 686LN-M4e that were derived from the same parent cell line. We expect that this system will provide a powerful tool for future detection and quantification of cancer cells from various tumor stages, and offer a platform to examine the effect of drug therapies on cancer cells or to customize drug therapies for cancer cells. Submitting author: Hyunsoo Kim, Dept. Electrical and Computer Engineering, Texas A&M University, College Station, Texas 77843, USA, Tel: +1-979-845-9686; E-mail: [email protected] Please upload during registration.
