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ID Proposals_Final Name: Stephanie Pouch Institution: The Ohio State University College of Medicine Email: [email protected] Did you submit this proposal on behalf of an ASTS or AST committee?: No If yes, please indicate which committee: Specialty: Heart Infectious Disease Kidney Liver Lung Pancreas Presentation Type: Interactive (Smaller group or round table) Symposium Proposed Session Title: The MDRO-Colonized Recipient: Challenges and Strategies for Optimizing Outcomes Proposed Moderators: Stephanie Pouch, MD, MS, The Ohio State University College of Medicine and Shirish Huprikar*, MD, Icahn School of Medicine at Mount Sinai *Camille Kotton – might replace SH here as he’s speaking elsehwere. Other potential speakers (from other program submissions): Dong Heun Lee, Drexel (has data on MDR swabs and SOT) David van Duin, UNC Dan Kaul, Michigan Ann Misch UWisc Goals and Objectives: Multidrug-resistant organisms (MDROs), including methicillin-resistant Staphylococcus aureus, vancomycin- and daptomycin-resistant enterococci, carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa, and Burkholderia spp., pose a serious threat to patient and graft survival, and limited therapeutic options often necessitate the use of older, toxic antimicrobials. Furthermore, the optimal management of transplant recipients with a history of pre-transplant colonization or infection due to MDROs remains unclear. The goals and objectives of this IDCOP-sponsored, interactive, case-based symposium are for the participant to understand: 1.The impact of recipient pre-transplant MDRO colonization/infection on post-transplant outcomes. 2.Waitlist management strategies (e.g., decolonization) for patients listed for transplantation who have a history of MDRO colonization/infection. 3.Peri- and post-operative management of organ transplant recipients colonized with MDROs (e.g., alteration of perioperative prophylaxis, duration of therapy). ID Proposals_Final Name: Shirish Huprikar Institution: Mount Sinai Email: [email protected] Camille Kotton – outstanding speakers, cutting edge information, top tier priority for ID and transplant community at large Did you submit this proposal on behalf of an ASTS or AST committee?: Yes If yes, please indicate which committee: ID COP Specialty: Administrative Heart Infectious Disease Kidney Liver Pancreas Pediatric Pharmacy Small Bowel Presentation Type: Lecture/Didactic Symposium Proposed Session Title: Infected Donors: Expanding the Donor Pool & The Risk of Avoiding All Risk Proposed Moderators: Mike Ison, Northwestern and Cameron Wolfe, Duke Presentation #1: PHS Increased Donors: Can We Do More? Proposed Speaker: Nicole Theodoropolous, University of Massachusetts Presentation #2: DTAC Perspectives on Expanding the Donor Pool Proposed Speaker: Cameron Wolfe, Duke Presentation #3: Hepatitis C D+R-: The New Frontier? Proposed Speaker: Peter Reese, University of Pennsylvania Goals and Objectives: Highlight the infected donor as an opportunity to safely expand the donor pool ID Proposals_Final Name: Joanna Schaenman Institution: David Geffen School of Medicine at UCLA Email: [email protected] Camille Kotton – outstanding speakers, cutting edge information, top tier priority for ID and transplant community at large, one of our most well attended sessions every year, and this one covers both the basics and cutting edge information. Did you submit this proposal on behalf of an ASTS or AST committee?: No If yes, please indicate which committee: Specialty: Basic Science/Immunology Heart Infectious Disease Kidney Liver Lung Pancreas Pediatric Pharmacy Small Bowel Translational Vascularized Composite Allograft Presentation Type: Lecture/Didactic Symposium Proposed Session Title: CMV in 2017: What’s Hot, What’s New? Proposed Moderators: Deepali Kumar, University of Toronto and Raymund Razonable, Mayo Clinic Presentation #1: Negative Impacts of CMV on the Transplant Allograft & Optimal Prevention Proposed Speaker: Raymund Razonable, Mayo Clinic Presentation #2: The T Cell Response to CMV Infection: Bench to Bedside Proposed Speaker: Laurie Snyder, Duke University Presentation #3: Anti-CMV Armamentarium of the Future Proposed Speaker: Camille Kotton, Massachusetts General Goals and Objectives: This session has been endorsed by the Infectious Diseases, Basic Science, and Kidney/Pancreas COPs. Objectives: CMV infection continues to cause significant morbidity and mortality after solid organ transplant, and has also been implicated in causing negative impact on the transplant allograft. This symposium will review the latest discoveries in the field as they apply to the clinical care of transplant patients at risk for CMV infection and disease. This will include insights into CMV immunology and new potential bench-tobedside applications for monitoring; new approaches to treatment including updates on new antiviral therapies, vaccines, and other avenues for treatment; and the latest data on the deleterious effects of ID Proposals_Final CMV replication on the allograft. In addition to filling a gap in knowledge of CMV disease, this session will provide an opportunity for interaction between basic scientists and clinicians. Goals: 1. Describe the new antiviral medications in development for treatment of CMV as well as current vaccine trials, and the promise of adaptive cell transfer for treatment of CMV. 2. Understand the CMV virus-specific immune response as measured both in the basic science laboratory as well as the potential for new clinically useful testing modalities for measurement of an effective anti-CMV response in patients. 3. Understand the data linking CMV infection and negative allograft outcomes and the potential mechanism of this effect, including promotion of antibody production, stimulation of inflammation, and upregulation of fibrosis. ID Proposals_Final Name: Christie Thomas Institution: University of Iowa Email: [email protected] Camille Kotton – are there other BK symposia? I don’t see any. (If so, might pick those.) This is a bit obscure. I think many people want bread and butter info on BK. Perhaps we can discuss as a larger group? Based on unusual content, I would say this is lower tier priority for ID. Did you submit this proposal on behalf of an ASTS or AST committee?: No If yes, please indicate which committee: Specialty: Heart Infectious Disease Kidney Liver Lung Pancreas Presentation Type: Lecture/Didactic Symposium Proposed Session Title: Kidney disease and more in BKPyV infection: nephropathy in non-renal organ recipients; urinary tumorigenesis and therapeutic approaches Proposed Moderators: Volker Nickeleit MD, University of North Carolina and Christie P Thomas MD, University of Iowa Presentation #1: BKPyV and Urinary tumors Proposed Speaker: John C. Papadimitrou MD, PhD, University of Maryland Presentation #2: BKPyV nephropathy in non renal solid organ transplant recipients Proposed Speaker: Sarat Kuppachi MD, University of Iowa Presentation #3: Prevention and treatment of BKPyV infection and nephropathy: current solutions and future promises Proposed Speaker: John S Gill MD, University of British Columbia Goals and Objectives: BK polyoma virus (BKPyV)is a well-recognized cause of tubulointerstitial nephritis and progressive chronic kidney disease in kidney transplant recipients. Despite advances in screening and detection of BKPyV infection in this immunocompromised population, there are limited therapeutic options that have been shown to be of benefit. It has recently become clear that BKPyV like other polyoma viruses may be an oncovirus leading to urinary tumors. BKPyV induced nephropathy is also beginning to be recognized as a cause of CKD in non-renal solid organ transplant (NRSOT) recipients. The purpose of this symposium is to discuss emerging information about BKPyV and urothelial malignancies and to inform the attendees about the problem of BKPyV nephropathy following NRSOT and to provide an uptodate discussion of current therapies and new treatments that may be on the horizon. The symposium will be led by 3 leaders in their field. Relevant speaker publication: ID Proposals_Final JC Papadimitrou: http://www.ncbi.nlm.nih.gov/pubmed/26731714 Sarat Kuppachi: http://www.ncbi.nlm.nih.gov/pubmed/26985385 JS Gill: http://www.ncbi.nlm.nih.gov/pubmed/27257795 ID Proposals_Final Name: Shirish Huprikar Institution: Mount Sinai Email: [email protected] Camille Kotton – outstanding speakers, cutting edge information, top tier priority for ID and transplant community at large. This was hugely successful last year, hundreds of people at 7am on a Sunday. Did you submit this proposal on behalf of an ASTS or AST committee?: Yes If yes, please indicate which committee: ID COP Specialty: Heart Infectious Disease Kidney Liver Lung Pancreas Pediatric Pharmacy Small Bowel Presentation Type: Lecture/Didactic Symposium Proposed Session Title: Top Papers in Transplant Infectious Diseases Proposed Moderators: Jay Fishman, MGH and Atul Humar, University of Toronto Presentation #1: Top 5 Papers: Viruses Proposed Speaker: Lara Danziger-Isakov, University of Cincinnati Presentation #2: Top 5 Papers: Bacteria Proposed Speaker: Shirish Huprikar, Mount Sinai Presentation #3: Top 5 Papers: Fungi et al. Proposed Speaker: Robin Avery, Johns Hopkins Goals and Objectives: To highlight top Transplant ID papers ID Proposals_Final Name: Shirish Huprikar Institution: Mount Sinai Email: [email protected] Camille Kotton – middle tier priority Good speakers Nothing on antifungals at ATC2016, good to have at ATC2017 Did you submit this proposal on behalf of an ASTS or AST committee?: Yes If yes, please indicate which committee: ID COP Specialty: Heart Infectious Disease Kidney Liver Lung Pancreas Pediatric Pharmacy Small Bowel Presentation Type: Lecture/Didactic Symposium Proposed Session Title: Antifungal Testing, Prevention, and Treatment Stewardship in SOT Proposed Moderators: Jay Fishman, MGH and Shirish Huprikar, Mount Sinai Presentation #1: Fungus Among Us: State of the Art Diagnostics Proposed Speaker: John Baddley, UAB Presentation #2: An Ounce or a Pound of Fungal Prevention? Proposed Speaker: Shahid Husain, University of Toronto Presentation #3: Antifungal Treatment in SOT Proposed Speaker: Shmuel Shoham, Johns Hopkins Goals and Objectives: 1. To highlight rational approaches to fungal infection diagnostic testing 2. To highlight the approaches to prevention of fungal infection in SOT 3. To highlight the unique considerations for treatment in SOT ID Proposals_Final Name: Michele Morris Institution: University of Miami Miller School of Medicine Email: [email protected] Camille Kotton – accept – middle tier priority for ID – would try hard to include, excellent speakers Did you submit this proposal on behalf of an ASTS or AST committee?: No If yes, please indicate which committee: Specialty: Infectious Disease Presentation Type: Lecture/Didactic Symposium Proposed Session Title: Emerging Infections in the Age of Global Warning - Implications for Transplantation Proposed Moderators: Camille Kotton, Massachusetts General Hospital and Raymund Razonnable, Mayo Clinic, Rochester Presentation #1: Zika Virus Infections - Screening Recommendations and Outcome Data Proposed Speaker: Clarisse Machado, University of Sao Paolo, Brazil Presentation #2: Nontuberculous Mycobacteria Infections - Management of Transplant Candidates and Recipients Proposed Speaker: Michele I. Morris, University of Miami Miller School of Medicine, Miami, FL Presentation #3: Strongyloides Infection Post-Transplant - Screening & Management of Donors & Recipients Proposed Speaker: Emily Blumberg, University of Pennsylvania, Philadelphia, PA – consider eplacing with Ricardo de la Hoz, Texas, to highlighted talented young members (EB not a guru on this topic per se) Goals and Objectives: To update transplant practitioners on the risks and challenges of pre-transplant screening and post-transplant management of these emerging pathogens. ID Proposals_Final Name: Elmi Muller Institution: University of Cape Town Email: [email protected] Camille Kotton – brilliant session (my favorite of all), outstanding speakers, should be very well attended, top tier for ID and entire transplant community Did you submit this proposal on behalf of an ASTS or AST committee?: No If yes, please indicate which committee: Specialty: Infectious Disease Kidney Liver Presentation Type: Lecture/Didactic Symposium Proposed Session Title: HIV positive transplantation Proposed Moderators: Michelle Morris, Director, Immunocompromised Host Section Division of Infectious Diseases University of Miami Miller School of Medicine and Jayme Locke, University of Alabama at Birmingham Presentation #1: HIV positive to positive transplantation - first year results and outcomes in the USA Proposed Speaker: Christine Durand, Johns Hopkins University Presentation #2: HIV positive to positive transplantation in South Africa - the unexpected outcomes and lessons learned Proposed Speaker: Elmi Muller, University of Cape Town Presentation #3: HIV positive transplantations: results with Maraviroc and MTOR inhibitors Proposed Speaker: Peter Stock, University of California San Francisco Goals and Objectives: Improving knowledge about the use of HIV positive donors. Improving knowledge about new ways of managing recipients who are HIV positive. ID Proposals_Final Name: christina chung Institution: Drexel University Email: [email protected] Camille Kotton – this belongs elsewhere not in ID Did you submit this proposal on behalf of an ASTS or AST committee?: No If yes, please indicate which committee: Specialty: Dermatology Presentation Type: Lecture/Didactic Symposium Proposed Session Title: Transplant Dermatology: New evidence, new approaches, and a fresh mandate for interdisciplinary collaboration Proposed Moderators: Christina Lee Chung, MD, Drexel University and Sarah T. Arron, MD, PhD, University of California Presentation #1: Morbidity and Mortality Proposed Speaker: Sarah T. Arron, MD, PhD, University of California San Francisco Presentation #2: Forging an Interdisciplinary Approach to Managing Post-Transplant Dermatological Care Proposed Speaker: Christina Lee Chung, MD, Drexel University Presentation #3: Transplant Dermatology in Skin of Color: New Data Demands New Approaches Proposed Speaker: Ellen N. Pritchett, MD, Henry Ford Hospital Goals and Objectives: 1. To define post-transplant mortality from skin cancer and identify risk factors 2. To describe models on which to build an effective and comprehensive transplant dermatology program 3. To identify differences in post-transplant dermatologic disease and skin cancer risk between White and non-White transplant recipients ID Proposals_Final ID Proposals_Final