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Comprehensive Neurological Oncology Program The Comprehensive Neurological Oncology Program at the University of California, Irvine is committed to advancing clinical care, education and research to help patients with brain, spinal cord and nerve tumors. The neurological oncology team works in tandem with the Chao Family Comprehensive Cancer Center, Orange County’s only National Cancer Institute-designated cancer center. The program faculty members are highly-experienced clinicians who are devoted to outstanding patient care, research and training of the next generation of neurological oncologists. UC Irvine has the only comprehensive brain tumor program in Orange County and is one of five such programs in Southern California. The world-class multidisciplinary team enlists the advanced clinical expertise of specialists in medical neuro-oncology, surgical neuro-oncology, radiation oncology, neuropathology, psychology and psychiatry. Our comprehensive brain tumor program is a leader in advanced treatments for brain, spinal cord and peripheral nerve tumors, offering patients comprehensive multidisciplinary care, the most advanced technology and the Daniela Bota, M.D., Ph.D., is a fellowship-trained and certified neurological oncologist and is the Medical Director of UC Irvine’s Comprehensive Brain Tumor Program. She specializes in the treatment of primary and metastatic brain tumors. Dr. Bota’s clinical interests include developing new treatments for high-grade and low-grade gliomas, as well as the treatment of cancer-induced cognitive deficits. She is the principal investigator for a number of brain and spinal cord tumor clinical trials that are benefits of leading-edge research. We provide: hope and support for patients and their families at all stages of disease; respect for patient autonomy, privacy and dignity, as well as individual needs, goals and priorities; cuttingedge, coordinated, integrated and timely multi-disciplinary patient care and service; excellence in clinical training and outcomes; academic achievement demonstrated by the development of new treatment approaches. For more information on how you can advance the work UC Irvine Health Advancement Dr. Daniela Bota and her team in UC Irvine’s Comprehen- 333 City Blvd. West, Orange, CA 92868 sive Neurological Oncology Program, please contact: 714.456.3573 or [email protected] currently enrolling patients at UC Irvine Medical Center. Comprehensive Neurological Oncology Program THE FUTURE Our cause and our passion are to take Survival for brain-cancer patients treated with chemotherapy has a dark side: “chemobrain”, the debilitating loss care of our patients. Our first step of memory and mental function that would be to modify chemotherapy often follows. The neurological oncology drugs so that they kill the cancer team is preparing a new weapon that could one day clear the cognitive fog. without killing the brain cells around By manipulating stem cells, they may be it. Our vision is to create a “one-stop closer than ever to placing a bull’s eye shop” for our patients, giving them the opportunity to have every member of the team – from surgeons to nutritionists – available at one single site. over the tumor cells and wiping them out while leaving the brain intact. This discovery is already being hailed as the first novel approach to tumor therapy in more than four decades. If this research proves to be effective, it could make a huge difference in the lives of cancer survivors, not only brain cancer patients, but those who beat other forms of cancer and also suffer from “chemobrain.” Among these would be breast cancer patients, who show a 70 percent rate of memory loss after chemotherapy. With $9 million in private support we will be able to: p Establish an Endowed Chair in Medical Neurological Oncology to attract and retain a Medical Co-Director for the Comprehensive Neuro-Oncology Program – $2 million p Establish an Endowed Chair in Surgical Neuro-Oncology to attract and retain a Surgical Co-Director of the Comprehensive Neuro-Oncology Program – $2 million p Establish an Endowed Chair in Brain Tumor Research to attract and retain a Ph.D. researcher in the field of Brain Tumor Biology – $2 million p Recruit the nation’s top two fellows for four year Neurological Oncology fellowships – $1 million p Annual support of research of the effects of chemotherapy on the young brain – $500,000 annually for 3 years p Support the Comprehensive Neurological Oncology Program by funding teams of researchers to explore and sustain new avenues of inquiry for the treatment of neurological malignancies – $500,000