Download Individual Investigator Award Slate: $38230344.00

Individual Investigator Award Slate: $38,230,344.00
November 2011
Application ID
RP120046
RP120052
RP120076
RP120094
Title
Mining the oncogenome: Functional
genomics approaches for screening
mutation drivers of pancreatic ductal
adenocarcinoma.
Super-high resolution imaging of tumor
Yuan, Baohong
angiogenesis in deep tissue
Novel mechanisms leading to telomere Bertuch, Alison A
dysfunction and cancer predisposition
Turn ON the Tumor Contrast for Surgical
Gao, Jinming
Resection of Head and Neck Cancers
RP120108
Improving on Anti-CTLA-4 Therapy
RP120124
Investigating the roles of p63 in miRNA
regulation in EMT and metastatic breast
cancer
Nuclear receptors and Hippo signaling in
liver cancer
Identification of Rheb and Notchdependent Pathways in Tuberous
Sclerosis Complex
RP120138
RP120168
Primary
Investigator
Scott, Kenneth L
Entity
Baylor College of Medicine
Recommended
Award*
$803,179.00
The University of Texas at
Arlington
Baylor College of Medicine
$1,095,905.00
The University of Texas
Southwestern Medical Center
at Dallas
The University of Texas M.D.
Anderson Cancer Center
The University of Texas M.D.
Anderson Cancer Center
$965,257.00
$1,378,796.00
Moore, David D
Baylor College of Medicine
$1,214,977.00
Karbowniczek,
Magdalena
Texas Tech University Health
Science Center - Abilene
$756,644.00
Sharma,
Padmanee
Flores, Elsa R
$937,896.00
$1,137,202.00
Application ID
RP120194
RP120214
RP120217
RP120241
RP120256
RP120258
RP120262
RP120280
RP120290
RP120298
RP120307
Title
Primary
Entity
Investigator
Defining and Subverting Allele-Specific Iyer, Vishwanath
The University of Texas at
Regulatory Networks in Cancer
R
Austin
Clinical Translation of Therapeutic siRNA Coleman, Robert
The University of Texas M.D.
in Solid Malignancies
L
Anderson Cancer Center
Role of IL-17 family cytokines in colon
Dong, Chen
The University of Texas M.D.
inflammation and cancer
Anderson Cancer Center
T-Cell Therapy After Hematopoietic
Cooper, Laurence The University of Texas M.D.
Stem Cell Transplantation
Anderson Cancer Center
Identify signature profile for
Yung, W. K.
The University of Texas M.D.
sensitivity/resistance to PI3K pathway
Alfred
Anderson Cancer Center
inhibitors to predict response to therapy
in Glioblastoma.
Towards Personalized Cancer Therapy: Myers, Jeffrey N
The University of Texas M.D.
Stratification of Oral and Pharyngeal
Anderson Cancer Center
Cancer Based on p53 Mutational Status
Functional and structural
Parada, Luis F
The University of Texas
characterization of small chemical
Southwestern Medical Center
compounds that arrest glioma stem cell
at Dallas
growth with high activity and specificity
Chemoprevention of Colon Cancer by
Wu, Xiangwei
The University of Texas M.D.
Targeting APC-deficient Cells for
Anderson Cancer Center
Apoptosis
Targeting hedgehog pathway for
Sun, Luzhe
The University of Texas Health
prostate cancer treatment
Science Center at San Antonio
Chimeric T cells for therapy of Hodgkin Savoldo, Barbara
Baylor College of Medicine
Lymphomas and CD30+ Non Hodgkin
Lymphomas
Factors Influencing Telomerase Action Wright, Woodring
The University of Texas
(Assembly, Modification, Recruitment,
E
Southwestern Medical Center
Activation): Potential Targets for
at Dallas
Telomerase Inhibition Cancer Therapy
Recommended
Award*
$1,125,799.00
$1,379,098.00
$1,285,789.00
$1,359,672.00
$1,000,179.00
$1,139,807.00
$1,499,532.00
$790,550.00
$875,252.00
$905,975.00
$1,002,052.00
Application ID
RP120311
RP120316
RP120326
RP120343
RP120352
RP120380
RP120390
RP120393
RP120394
RP120406
RP120408
RP120451
RP120459
Title
Primary
Investigator
Janowski,
Bethany A
Regulation of Cyclooxygenase-2 (COX-2)
Gene Expression by Noncoding RNAs in
Cancer
CBM complex-mediated signaling
Lin, Xin
pathways as potential therapeutic
targets for EGFR-induced cancer
In-Situ PET Imaging for Adaptive Proton
Shao, Yiping
Therapy
Gli Transcriptional Activity in Basal Cell Vokes, Steven A
Carcinomas
Mechanisms of CRM1-mediated nuclear
Chook, Yuh Min
export in cancer
Distinct microRNAs Regulate Prostate
Cancer Stem Cells
Control of cross-talk between ovarian
cancer cells and the tumor
microenvironment
Preclinical Development of TexaphyrinPlatinum Conjugates
Molecular Oncogenesis of NANOG in
Castration-Resistant Prostate Cancer
A New Role for Triptan Drugs in the
Treatment of Breast Cancer
Anti-Cancer Drugs to Treat Cancer Pain
Tang, Dean G
Naora, Honami
Sessler,
Jonathan L
Jeter, Collene R
Dalby, Kevin N
Gutstein, Howard
B
Novel Strategy for Treatment of HER2Claret, Francois
Positive Breast Cancer
X
Contribution of the BRIGHT transcription Tucker, Philip W
factor to autoimmune Diffuse Large Bcell Lymphoma
Entity
The University of Texas
Southwestern Medical Center
at Dallas
The University of Texas M.D.
Anderson Cancer Center
Recommended
Award*
$631,578.00
$915,974.00
The University of Texas M.D.
Anderson Cancer Center
The University of Texas at
Austin
The University of Texas
Southwestern Medical Center
at Dallas
The University of Texas M.D.
Anderson Cancer Center
The University of Texas M.D.
Anderson Cancer Center
$1,271,284.00
The University of Texas at
Austin
The University of Texas M.D.
Anderson Cancer Center
The University of Texas at
Austin
The University of Texas M.D.
Anderson Cancer Center
The University of Texas M.D.
Anderson Cancer Center
The University of Texas at
Austin
$1,275,000.00
$659,495.00
$684,209.00
$750,000.00
$727,029.00
$664,248.00
$1,010,289.00
$913,322.00
$864,748.00
$947,367.00
Application ID
RP120462
RP120474
RP120489
RP120505
RP120558
RP120583
RP120588
Title
Primary
Investigator
Pollock, Bradley
H
Entity
Environmental Determinants of
The University of Texas Health
Hepatocellular Carcinoma in South
Science Center at San Antonio
Texas
Enabling the structure determination of
Jiang, Qiu-Xing
The University of Texas
functional human telomerase
Southwestern Medical Center
holoenzyme
at Dallas
Transporter-Targeted Drug Delivery and Smith, Quentin R Texas Tech University Health
Treatment of Brain Metastases of Breast
Science Center at Amarillo
Cancer
Clinical and molecular characterization Davies, Michael A The University of Texas M.D.
of combined BRAF and MEK inhibitor
Anderson Cancer Center
treatment in patients with metastatic
melanoma resistant to BRAF inhibitor
alone
Development of a Novel High-resolution
Ye, Jing Yong
The University of Texas at San
Photoacoustic Microscopy System for
Antonio
Noninvasive in vivo Imaging of
Melanoma
A New Functional Genomics Approach to
Westbrook,
Baylor College of Medicine
Discovering Therapeutic Targets for
Thomas
Breast Cancer
Targeting the Acidic Tumor
Zheng, Jie
The University of Texas at
Microenvironment with Renal Clearable
Dallas
and pH Responsive Luminescent Gold
Nanoparticles
*Subject to contract negotiations
Recommended
Award*
$767,107.00
$681,709.00
$736,685.00
$1,016,800.00
$698,120.00
$1,102,029.00
$1,259,790.00