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Cellular Respiration ATP Adenosine Triphosphate o Organic molecule, contains high energy phosphate bonds o Energy used by all cells Hydrolysis = process of breaking the high energy bonds hydrogen bonds between the last two phosphates in ATP ATPase = enzyme that breaks ATP ATP + ATPase ADP ATP Synthetase = reverses hydrolysis, add a phosphate to ADP ADP+ ATP Synthetase ATP Cellular Respiration Break down nutrients (sugars) to CO and water o Large molecules complex molecules into smaller molecules Process is Exergonic (give off energy) o High-energy Glucose is broken into CO and H O 2 2 2 Needs to occur in the presence of oxygen o Glucose is oxidized and O2 is reduced (oxidation-reduction reaction or REDOX) Oxidation of glucose = remove e- from C6H12O6 Reduction = (e- passed to O2) Breakdown of one glucose results in 36 to 38 ATP molecules C6H1206 + 602 6CO2 + 6H20 (+e- + 36-38 ATP’s) What carries the electrons? + NAD Coenzyme (nicotinadenine dinucleotide) Aacts as the energy carrier It’s Reduced to NADH when it picks up two electrons and one hydrogen ion Other Electron Carriers FAD+ (Flavin adenine dinucleotide) Reduced to FADH 2 Stages of Cellular Respiration Glycolysis = cytoplasm Krebs cycle = mitochondria Electron Transport chain = mitochondria Glycolysis Takes place in cytoplasm Anaerobic (doesn’t use oxygen, but can occur in the presence) Uses 2 ATP (input) o Glucose split into 2 molecules (pyruvate & pyruvic acid) Produces 2 NADH and 4 ATP (output) Pyruvate (oxidized to Acetyl CoA and CO ) is removed 2 Fermentation Occurs in cytoplasm Occurs when O NOT present (anaerobic AND oxygen will stop process) o Nets only 2 ATP Lactic Acid fermentation = muscle cells (makes muscles tired) Alcoholic fermentation = yeast (produces ethanol) 2 Krebs cycle Occurs in mitochondria Requires Oxygen (Aerobic) Cyclical series of oxidation reactions o Gives off CO and produces one ATP per cycle 2 o And produces: 3NADH, 1FADH , and 2CO 2 2 Two cycles per glucose molecule Produces two ATP One Glucose molecule (in the Krebs Cycle) produces o 6NADH, 2FADH , 4CO , and 2ATP 2 2 Electron Transport Chain Occurs across inner mitochondrial membrane o Basically swapping elections across the membranes in a series of reactions until ATP produced Produces: 34 ATP and H O Uses coenzymes NAD+ and FAD+ to accept e- from glucose o NADH = 3 ATP’s o FADH = 2 ATP’s 2 2