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IV Therapy NRS 108 Majuvy L. Sulse RN, MSN, CCRN Objectives of IV therapy Achieve & maintain normal fluid & electrolyte balance Achieve optimal nutritional status Maintain homeostasis through blood & blood products administration Medication administration Composition & Distribution of body fluids Component Water electrolytes Distribution IntracellularExtracellular Interstitial-Lymph Intravascular-plasma Transcellular-CSF, pleural, peritoneal & synovial Movement of body fluids Osmosis Diffusion Filtration Active transport Osmolarity vs. Osmolality & Tonicity Osmolarity Number of milliosmosles in a liter of solution Volume Normal osmolarity of plasma and ECF 270-300 MOS/L Osmolality Number of milliosmoles in a kilogram of solution Weight Tonicity- ability of solution to cause a change in water movement across a membrane due to osmotic pressures Hypertonic Isotonic Hypotonic Osmolarity greater than Osmolarity equal to body fluid body fluid Osmolarity is less than body fluid Shifts fluid into blood plasma by moving fluid from tissue cells Keeps fluid in the intravascular volume Shifts fluid from intravascular to the tissue cells Uses: Hypovolemia hyponatremia Uses: dehydration, KVO, intravascular compartment expansion Uses: Expand and hydrate cells in cellular dehydration Watch for: Increase in BP Fluid overload Fluid overload Low Hb/Hct levels Monitor Na levels Hypotension Examples of IVF Hypertonic NaCl 3%-5% D5 NaCl D5LR D5.45 NaCl Isotonic 0.9% NaCl Hypotonic LR D5W Albumin 5% (colloid) 0.45% NaCl 0.33% NaCl 2.5% Dextrose Colloids Proteins/large molecules Increased osmotic pressure-plasma volume expanders Uses: burns, hemorrhage, surgery Types: dextran-40-70 (decreases blood viscosity &reduces platelet adhesiveness) albuminMannitol Nurse Alert: Monitor for blood pressure Crystalloids Substances easily dissolved, pass through semi permeable membrane Uses: replace fluid loss & promote urine output Types: Dextrose solutions sodium chloride solutions multiple electrolyte solutions IV Sites & Cannulas Site-start from periphery, use vein on non dominant side, avoid areas of previous venipunctures, avoid areas of flexion, veins on a surgically/neurologically compromised limb Catheter gauge-amount of fluid and how long it will infuse, viscosity of fluid, size & condition of vein Common IV sites 1-cephalic 2-basilic 3-median cubital 4- medial cutaneous nerve of forearm medial antebrachial cutaneous n. 5-lateral cutaneous nerve of forearm lateral antebrachial cutaneous n. Standard intravenous catheter Used for continuous fluid administration Not considered for long term therapy Flow rate regulated manually by clamp or regulated by an automatic pump Heparin Lock Intermittent infusion lock Used when fluid therapy is no longer required Used to administer intermittent medication Used to maintain venous access Needs flushing to maintain patency Medication Administration Added to primary intravenous fluids-large volume infusions Added via piggyback-small amount IV fluid in a secondary set connected to Y port 10 mEq KCL to D51/2 NS 1amp MVI to D51/2 NS antibiotics Given via IV -push-confirm placement of catheter Lasix Intravenous Therapy & Piggyback Medication Administration Preparation Always practice strict hand washing Preparation for additives Vial or ampule- measure appropriate amount Powder- mix with diluents Common complications-Local Hematoma Leakage of blood into surrounding insertion site Causes: Signs/symptoms Perforation of opposite vein wall Needle slips out of vein Insufficient pressure after venipuncture is terminated IMMEDIATE SWELLING, ECCHYMOSIS Interventions Immediate pressure, sterile dressing, cold compress over 24 hrs then warm compress Common complications-Local Infiltration Leakage of fluid into surrounding insertion site Causes: Needle dislodges and fluid infuses into the tissues S/S Edema, area cool to touch, no blood return Interventions D/c Iv, sterile dressing, warm compress, elevate Common complications-Local Tissue injury- may include necrosis and sloughing, deprive patient of fluid, infection, permanent damage Causes S/S Infiltration of hypertonic, toxic, acidic or alkaline solutions Pain, swelling, color changes, sloughing Interventions Notify MD, follow treatment Common complications-Local Phlebitis-inflammation of vein Causes: S/S Prolonged infusion, traumatic entry, fluid tonicity, cannula size, improper securing at site, poor sterile technique Redness, warmth, swelling, burning pain, low flow rate Interventions D/c IVF, warm compress Common complications-Local Thrombosis-formation of thrombose without inflammation Causes: Damage to intima of vein, deposition of fibrin, clot occlusion S/S Little to no pain, low/no flow rate Interventions D/c IV DO NOT IRRIGATE Common complications-Local Thrombophlebitis-clot formation with inflammation of vein Causes: Damage to intima of vein, fibrin deposit, clot, occlusion S/S Pain, redness, warmth, swelling Interventions D/C IV, do not irrigate, notify MD, warm compress, elevate Common complications-Local Clotting of cannula Causes: Empty IV or interrupted flow, kinked tubing, failure to flush heparin lock S/S IV flow stops, backflow of blood in IV tubing Interventions Aspirate clot (do not use force) restore flow Complications-Systemic Infection Causes: introduction of microorganism at catheter insertion or during therapy, contaminated equipments or solutions S/S Dependent upon the degree and the individual Interventions Notify the MD, supportive care Complications-Systemic Air embolism Causes: S/S Introduction of air during insertion of central line, administration tubing, solution run dry Pallor, cyanosis, dyspnea, cough, tachycardia, syncope, shock Interventions Place client on Left side, emergency supportive care, notify MD Complications-Systemic Thrombolism- obstruction of blood vessel by carried via the circulatory system Causes: S/S Release of clot from the catheter tip via manipulation or tubing Depending upon size & location of clot Interventions Notify MD, monitor VS, supportive nursing care, treat as per MD Complications-Systemic Allergic reaction- hypersensitivity to solution or medication Causes: S/S Antigen-Antibody reaction Skin: rash, urticaria Respiratory: dyspnea, stridor, wheezing Non specific: nausea, vomiting, chest tightness Interventions Stop IV, change tubing, run KVO, notify MD Complications-Systemic Circulatory overload-infusion of excessive fluids Causes: Failure to monitor rate S/S Edema, puffy eyelids, SOB, rales, hypertension Interventions Decrease Iv rate, raise of head of bed up, monitor VS, notify MD, O2 Complications-Systemic Speed shock-related to toxic concentration of drug Causes: S/S Rapid administration of IV drug Tachycardia, hypotension, syncope, shock, cardiac arrest Interventions Stop drug infusion, KVO fluids, Monitor VS, notify MD Vascular Access Devices Short Peripheral catheters Midline Catheters PICC-peripherally inserted central catheters Nontunneled Percutaneous Central Catheters Implanted ports Dialysis catheters Catheter care & Maintenance Educate client Assessment Securing& dressing the catheter Changing administration sets Controlling infusion pressure Obtaining blood samples from catheter Keeping catheter patent Discontinuing catheter IV Flow Rate Calculations Know tubing Macro drip 10gtts 15 gtts 20 gtts All equals 1 cc Micro drip 60 gtts= 1cc IV Flow Rate Calculations Must know Total volume to be infused Calibration of tubing Time ordered for infusion Formula flow rate= volume x calibration time in minutes IV Flow Rate Calculations Order: 1000 ml D5w TO INFUSE OVER 8 HOURS. Drip factor: 20 gtts/ml. Calculate the correct gtt/min. 1000ml x 20gtt= 20,000=41.6gtts/min 8x60 480 IV Flow Rate Calculations Ordered D5W to infuse at 83 ml/hr. The drop factor is 10. 10 x 83= 1 x 83= 13.8 or 14gtts/min 1 hr x 60 min 6 Calculating drug doses Formula: Dose= Rate x concentration Dose= expressed in different units: mg/hr, mg/min, units/hr, etc Rate=always in ml/hr as IV pumps are used to administer these drugs Concentration=found on the label of the drug which maybe in mg/ml, units/ml or mcg/ml Calculating drug doses 1) You need to administer 800 units of heparin. The label states there are 25,000 Units/500 ml of fluid. calculate the rate you will set on the pump 500ml 25,000 U x 800 U= 40000 ml =16ml/hr 1 hr 25000 Calculating drug doses At the beginning of your shift, you note that Theophylline 1 gm/500ml is infusing at 20 ml/hr. You have an order to administer Theophylline at 40 mg/hr. Is the rate correct? 500ml x 1000mg 40 mg =20000 ml =20ml/hr 1 hr 1000hr