Download Course Structure and Syllabus of B. Sc. MLT

UNIVERSITY POLYTECHNIC
BIRLA INSTITUTE OF TECHNOLOGY
MESRA : RANCHI
B. Science Medical Laboratory Technology
COURSE STRUCTURE
1st Semester
Course No.
BMT 1001
BMT 1003
BMT 1005
BMT 1007
BMT 1009
Theory
Human Anatomy &
Physiology –I
Chemistry for Medical Lab.
Technologist
Basics of Electrical &
Electronics Engg.
Laboratory Mathematics
(Pharmaceutical
Calculation).
Communication Skill
Unit
1.0
Course No.
BMT 1002
Unit
0.5
BMT 1004
Laboratory
Human Anatomy &
Physiology Lab.-I
Chemistry Lab.
1.0
1.0
BMT 1006
Basic Electrical Lab
0.5
1.0
BMT 1008
Basic Electronics Lab.
0.5
1.0
5.00
GA 1001
PT & Games/CA
0.5
2.5
0.5
II Semester
Course No.
BMT 2001
BMT 2003
BMT 2005
BMT 2007
BMT 2009
Theory
Human Anatomy &
Physiology – II
Hematology – I
Clinical Chemistry - I
Introduction to
Computer Science
Histology
Unit
1.0
Course No.
BMT 2002
1.0
1.0
1.0
BMT 2004
BMT 2006
BMT 2008
Laboratory
Human Anatomy &
Physiology Lab.-II
Hematology Lab.-I
Clinical Pathology
Programming Lab.
1.0
5.0
SCA 2001
PT & Games/CA
Unit
0.5
0.5
0.5
0.5
0.5
2.5
III Semester
Course No.
BMT 3001
BMT 3003
BMT 3005
BMT 3007
BMT 3009
Theory
Clinical Chemistry - II
Biomedical
Instrumentations
Digital Electronics System
Medical Microbiology
Instrumentation
&
Measurement System
Unit
1.0
1.0
Course No.
BMT 3002
BMT 3004
Laboratory
Unit
Clinical Chemistry Lab.-I 0.5
Instrumentation Lab.
0.5
1.0
1.0
1.0
BMT 3006
BMT 3008
SCA 3001
Digital Electronics Lab
Microbiology Lab.-I
PT & Games/CA
5.0
0.5
0.5
0.5
2.5
IV Semester
Course No.
BMT 4001
BMT 4003
BMT 4005
BMT 4007
BMT 4009
BMT 4011
BMT 4013
Theory
Applied Microbiology
Hematology – II
Histopathology
Parasitology & Cytology
Elective
Immunopathology
Unit
1.0
1.0
1.0
1.0
Course No.
BMT 4002
BMT 4004
BMT 4006
BMT 4008
Laboratory
Microbiology Lab.-II
Hematology Lab.-II
Histopathology Lab.
Parasitology Lab
Unit
0.5
0.5
0.5
0.5
1.0
BMT 4012
or
.
Elective
Microprocessor Lab
PT & Games/CA
0.5
or
Bio-signal acquition System
Elective
Intro. Microprocessor
SCA 4001
0.5
V Semester
Course No.
Theory
Unit
Course No.
Laboratory
Unit
BMT 5001
Clinical Chemistry -III
1.0
BMT 5002
Clinical Chemistry Lab.-II
0.5
BMT 5003
BMT 5005
Forensic Medicine & Ethics
Material Management
1.0
1.0
BMT 5004
BMT 5006
Bacteriology Lab.
Histopathology Lab.-II
0.5
0.5
BMT 5007
BMT 5009
Serology & Virology Elective
Hemotology – III
1.0
1.0
BMT 5008
Serology & Virology Lab.
0.5
BMT 5011
or
Clinical Instrumentation
Biomedical imaging
devices & concept
BMT 5010
Or
Hematology Lab.- III
Or
Clinical Instrumentation
Lab.-II
BMT 5013
Elective
1.0
BMT 5012
VI Semester
BMT 6001
BMT 6002
Clinical Internship Project
Seminar
6.0
1.0
0.5
Elective
0.5
1st Semester
Course No.
BMT 1001
BMT 1003
BMT 1005
BMT 1007
BMT 1009
Theory
Human Anatomy &
Physiology –I
Chemistry for Medical Lab.
Technologist
Basics of Electrical &
Electronics Engg.
Laboratory Mathematics
(Pharmaceutical
Calculation).
Communication Skill
Unit
1.0
Course No.
BMT 1002
Unit
0.5
BMT 1004
Laboratory
Human Anatomy &
Physiology Lab.-I
Chemistry Lab.
1.0
1.0
BMT 1006
Basic Electrical Lab
0.5
1.0
BMT 1008
Basic Electronics Lab.
0.5
1.0
5.00
GA 1001
PT & Games/CA
0.5
2.5
0.5
BMT 1001 Human Anatomy & Physiology – I
(i)
The anatomic and physiological organization of human body and integrated physiology.
(ii)
Cell organization and function.
(iii)
Skeletal system, bones, joint and muscle.
(iv)
Body fluid and their significance.
(v)
Blood morphology, chemistry & function.
(vi)
Respiratory system.
(vii)
Cardiovascular system.
(viii) Alimentary system, mechanism and physiology of digestion and absorption.
(ix)
Liver structure and function.
Books Recommended:
1.
Best & Tayler: “Best and Taylor’s Physiological Basis of Medical Practice,” William &
Wilkins: Baltimore.
2.
Chaurasia: “Huaman Anatomy – Regional & Applied.” Part I, II, III, CBS Publishers &
Distributors, New Delhi.
3.
C.C. Chatterjee: “Human Physiology,” Vols. I & II, Medical Allied Agency, Calcutta.
4.
Shalya: “Human Physiology,” CBS Publishers & Distributors.
5.
Edwards: “Davidson’s Principles Practice of Medicine,” ELBS/Churchill Livingstone.
6.
Ganong: “Review of Medical Physiology,” Prentice Hall International.
7.
Guyton & Hall: “Textbook of Medical Physiology,” WB Saunders Company.
8.
Keele et at.: “Samson Wright’s Applied Physiology,” Oxford University Press.
9.
McNaught & Callander: “Illustrated Physiology,” Churchill Livingstone.
10.
Parmer: “Health Education and Community Pharmacy,” CBS Publishers.
11.
Tortora & Anaganodokos: “Principles of Anatomy and Physiology,” Harper and Row
Publishers N.Y.
12.
Vander et al.: “Human Physiology,” Tata McGraw Hill Publisher Co.,
BMT – 1003 : CHEMISTRY FOR MEDICAL LAB. TECHNOLOGY
1. Chemistry of matter & measurement, molecules & ions, formula equations and mole concept
stoichiometry, atomic & molecular weight, qualitative informations from balance equations.
(5)
2. Aqueous solutions reactions, pH, acids & bases
(5)
3. Atomic structure, periodic table & periodic properties
(5)
4. Basic concepts of Chemical bonding
(5)
5. Thermo Chemistry – Nature of energy, heat & enthalpy change, calorimetry, Hess’s law fuels.
(5)
6. Introduction to colloids & surface phenomena electrophoresis
(5)
6. Chemistry of inorganic constituents in body fluids, Radioistopes & their use in life system.
(5)
Books Recommended:
1.
2.
University Chemistry by Bruce Mahan
Engineering Chemistry by Shashi Chowla.
BMT – 1005 BASICS OF ELECTRICAL & ELECTRONICS ENGINEERING
Electrical
Electrical elements their classification and characteristics : Resistance, Inductance, Capacitance, voltage
source, current source.
(5)
DC circuits : KCL & KVL equations, Loop current & node voltage method series & parallel resistance
(5)
Theorems : Superposition, Thevenin’s & Nortons, Maximum Power transfer
(4)
AC single phase circuit : Common signals & their wave form, RMS & Average value, form factor,
phasor quantities, impedance, power, power factor, apparent power.
(6)
Transformer Introduction
(2)
Electronics
Introduction to semiconductor : Intrinsic & Extrinsic, PN junction, Diode characteristic
(3)
Rectifier-Half wave, Full wave, Bridge rectifier, Rectifier filter, SMPS
(5)
Fundamentals of Transistor, Characteristic, C.B. & C.E. Common Emitter Transistor Amplifier,
Introduction to lod line & Q-point, Frequency response of amplifier.
(6)
Introduction to feed back in amplifier, Introduction to oscillator. Barkhausen criterion
(4)
Introduction to FET, & op-amp, CMRR.
(4)
Text Books :
1.
2.
Basic Electrical Science & Technology by K. Murugesh Kumar (Vikas Publishing)
Electronics Fundamentals & Applications, D. Chattodhay and P.C. Rakshit (New Age
International).
Reference Books :
1.
2.
3.
Basic Electrical Engineering by V.N. Mittle, Tata McGraw Hill Publishing Company
Electronics Devices and Circuits Theory by R.L.Boylestade and L.Nashelsky (PHI)
An introduction to Electronic Devices and Circuits by Allen Mottershed
BMT 1007: LABORATORY MATHEMATICS
1.
Arithmatic
Number and numerals, kinds of numbers, Arabic numerals, Roman numerals, Common and
decimal fractions, Ratio, proporticon, and variation, Dimension analysis, significant figures,
Estimation, Percentage of errors, Measurement of volume, Measurement of weight, Aliquor
method of weighing and measuring, Least weighable quantity method of weighing, logarithms.
(10)
2.
Metric system
Measurement of length, volume, weight, fundamental computations, Relation of metric to other
systems of Measurements.
(5)
3.
Percentage and ratio strength calculation.
Percentage, Percentages of preparations. Weight-in-volume, volume-in-volume, weight-inweight. Use of percent in compendial standards. Ratio and strength, simple conversions of
concentrations to mg/ml. Expressing clinical laboratory test values, Parts per million (PPM).
(10)
4.
Graphical methods
Linear relationships on Rectangular Graph paper, Linear relationships on semi-logarithmic
graph paper, Other methods of data representation.
(5)
5.
Basic statistical methods
Array, Frequency distribution, Averages, Measures of variation, some aspects of probability.
(5)
BMT – 1009: COMMUNICATION SKILLS
1.
Report Writing
Introductory, Objectives, Characteristics, Types, Importance, Structure of Report, Writing report
(First draft Visual Aids)
(5)
2.
Common Errors
Errors in use of Noun, Pronoun, Adjective, Adverb, Verb, Preparation & Article.
(5)
Vocabulary
One Word Substitution, Antonyms, Synonyms, Use of Idioms and Phrases
(6)
Letter of Application
Letter of Complaints, Letter of Refusal, Acceptance, Application for leave etc.
(4)
5.
Paragraph Development : Technique for Paragraph development
(4)
6.
Reading Comprehension : Techniques for Good Comprehension
(8)
7.
Medical Terminology
(2)
8.
Oral Communication
(6)
3.
4.
Interviews : Introduction, objectives, types of interviews, etc.
BMT - 1002 : HUMAN ANATOMY & PHYSIOLOGY LAB.-I
Laboratory based on BMT1001 Human Anatomy & Physiology-I
II Semester
Course No.
BMT 2001
BMT 2003
BMT 2005
BMT 2007
BMT 2009
Theory
Human Anatomy &
Physiology – II
Hematology – I
Clinical Chemistry - I
Introduction to
Computer Science
Histology
Unit
1.0
Course No.
BMT 2002
1.0
1.0
1.0
BMT 2004
BMT 2006
BMT 2008
Laboratory
Human Anatomy &
Physiology Lab.-II
Hematology Lab.-I
Clinical Pathology
Programming Lab.
1.0
5.0
SCA 2001
PT & Games/CA
Unit
0.5
0.5
0.5
0.5
0.5
2.5
BMLT 2001 Human Anatomy & Physiology – II
(i)
Urinary System
(ii)
Nervous System
(iii)
Endocrine and Exocrine glands and their functions
(iv)
Reproductive System
(v)
Lymphatic System
(vi)
Skin - Structure & its functions
(vii)
Eye & Ear
(viii) Nutrition - Carbohydrate, Protein, Fats
Books Recommended:
1. Best & Tayler: “Best and Taylor’s Physiological Basis of Medical Practice,” William & Wilkins:
Baltimore.
2. Chaurasia: “Huaman Anatomy – Regional & Applied.” Part I, II, III, CBS Publishers &
Distributors, New Delhi.
3. C.C. Chatterjee: “Human Physiology,” Vols. I & II, Medical Allied Agency, Calcutta.
4. Shalya: “Human Physiology,” CBS Publishers & Distributors.
5. Edwards: “Davidson’s Principles Practice of Medicine,” ELBS/Churchill Livingstone.
6. Ganong: “Review of Medical Physiology,” Prentice Hall International.
7. Guyton & Hall: “Textbook of Medical Physiology,” WB Saunders Company.
8. Keele et at.: “Samson Wright’s Applied Physiology,” Oxford University Press.
9. McNaught & Callander: “Illustrated Physiology,” Churchill Livingstone.
10. Parmer: “Health Education and Community Pharmacy,” CBS Publishers.
11. Tortora & Anaganodokos: “Principles of Anatomy and Physiology,” Harper and Row Publishers
N.Y.
12. Vander et al.: “Human Physiology,” Tata McGraw Hill Publisher Co.,
BMLT 2003 : HEMATOLOGY - I
1. Introduction to hematology.
2. Formation of blood, composition of blood, functions of blood.
3. Various anticoagulants and their uses, mode of action of anticoagulants, merits and demerits.
4. Physiological variations in Hb , PCV, TLC, Platelets
5. Quality assurance in hematology.
6. Haemoglobinometry, various methods of estimation of Hb, errors involved and standardization
of instruments for adaptation for Hb estimation.
7. Haemocytometry, procedures of cell counts, visual as well as electronic, red cell, leucocytes and
platelets counts, error involved in and means to minimize such error.
8. Morphology of normal blood cells and their identification.
9. Erythrocytes sedimentation rate, factors influencing ESR and various procedures for its
estimation with their significance.
10. Routine examination of urine.
11. Examination of biological fluids such as CSF etc.
12. Examination of semen
BOOKS:
1. Baker et al: An introduction to medical laboratory technology.
2. Charles F. Seiverd: Hematology for medical technologists
3. Arthur Simmons: Technical hematology
BMLT 2005 : CLINICAL CHEMISTRY – I
Introduction to Biochemistry: Bioconstituents, Enzymes, Metabolism, Clinical Biochemistry,
Nutritional Biochemistry
Biochemistry of Cell Membrane:
Enzymes: Chemical Nature of the Enzymes, Properties of Enzyme, Factors affecting Enzyme Activity,
Enzyme Inhibition, Mechanism of Enzyme Action, Nomenclature and Classification of Enzymes,
Isoenzymes, Multienzyme Complex, Diagnostic Applications of the Enzymes, Therapeutic uses of
Enzymes.
Bioenergetics and Biological Oxidation:
Application of Thermodynamics in Biological Reaction, Biological Oxidation Reduction, Substrate
Level Phosphorylation, Energy Rich Compounds.
Chemistry and Metabolism of Carbohydrates:
Carbohydrate of biological importance, Storage Carbohydrates: Glycogen Synthesis and breakdown,
Glycolysis, TCA Cycle, HMP Shunt Pathway, Uronic Acid Pathway, Gluconeogenesis, Glucose
Tolerance, Blood Sugar Level, Glycosuria and Diabetes Mellitus, Disorder of Carbohydrate metabolism.
Chemistry and Metabolism of Lipids:
Lipids of biological importance, Derived lipid, Sterols, Bile acids, Oxidation of Fatty acids, Ketolysis
and ketogenesis, Biosynthesis of Fatty acids, Metabolism of Phospholipids, Metabolism of Cholesterol,
Disorders of Lipid Metabolism.
Chemistry and Metabolism of Amino acids and Protein:
Characteristics of Amino acid and Proteins, Biological Value of Proteins, Metabolism of Amino acids
and Proteins, Urea Cycle, Disorders of Protein Metabolism, Chemistry and Metabolism of Nucleic
Acids.
Books Recommended:
1. Harper’s Review in Biochemistry: A.K. Murray, D.K. Granner, P.A. Mayers and V.W. Rodwell:
Prentice Hall of India Ltd., New Delhi.
2. Fundamental of Clinical Chemistry R.W. Tietz (Ed.) W.B. Saunders Co., Philadelphia USA.
3. Clinical Chemistry (Principles and Techniques): R.J. Henry, D.C. Cannon, J.W. Winkelman:
Harper & Row Publishers.
4. Text Book of Biochemistry by Agarwal’s: Goel Publishing House.
5. A Text Book of Medicinal Biochemistry: R.L. Nath: New Age International Publishers.
6. Stryer: “Biochemistry,” 4th ed., W.H Freeman & company, 1995 (Reprint 1999).
7. Mussay et al.: “Harpers Biochemistry,” Prentice Hall International.
8. Marlin et al.: Harpers Biochemistry,” 24th ed., Lange Medical Publications, 1996.
9. Lehninger: “Biochemistry,” 3rd ed., Worth, CBS Publisher & Distributors 2000.
10. Conn & Stumpf: “Outline of Biochemistry,” 5th ed., John Wiley & Sons, 2003.
11. Harrow & Mazur: “Text book of Biochemistry,” W.B. Saunders, Philadelphia.
12. Jayaraman: “Laboratory Manual in Biochemistry,” Wiley Eastern Ltd., New Delhi.
13. Satyanarayan: “Biochemistry,” Book & Allied (P) Ltd., Reprint 2000.
Singh: “Practical manual of Biochemistry,” 4th ed., CBS Publishers & Distributors, 2001.
BMLT 2007 : INTRODUCTION TO COMPUTER SCIENCE
Module : I
COMPUTER ORGANIZATION AND PROCESSING OF DATA : Introduction, Input Units, The
Central Processing Unit, How does CPU work ? Types of CPU Memory, The RAM (Read Only
Memory) Chip, CMOS RAM, The Data Flow on the Motherboard, The PC Buses, The I/O Buses, RAM
(Random Access Memory).
Module : II
INPUT AND OUTPUT DEVICES AND STORAGE DEVICES CONCEPTS : Input Devices,
Output Devices, Drives are Storage Media, Hard Disks, The Optic Media, Optic Data Storage, CD-R,
CD-RW, The DVD.
COMPUTER SOFTWARE : Starting up the Computer : Software Types, Software Creation and
Programming Languages, The Operating System, User Interface, System Software, Which operating
systems, 32 Bit Drives, File Systems, The Four Disk Areas, Partitioning with FDSK, Loader and
Linker, Compiler, Assembler and Interpreter, Types of Operating Systems, Applications Software.
Module : III
FILE ORGANISATION AND ACCESS CONCEPTS : Representation of Data, Storage Mapping; A
Physical Representation of Data, File Systems, Searching and Sorting Data, Qyuicksort, Sequential File
Processing, Random File Processing, Indexed Sequential Access.
Module : VI
DATA BASE DESIGN AND MANAGEMENT : Introduction, Basic Terminology and Concepts, Data
Models, Entity Relationship Diagram, Creating Database, Query Languages, Security and Privacy
Measures, Application and Trends, Principles of Database Management.
STRUCTURED QUERY LANGUAGES : Introduction, Basics of the Select Statement, Conditional
Selection, Joins, Miscellaneous SQL Statements, Miscellaneous Topics.
Module : V
NUMBER SYSTEMS : Number Reprsentation and Arithmetic, Number System, Decimal System,
Binary Numbring System, Octal System, Hexadecimal System. Radix Conversions, Arithmetic
Operations of Octal Numbers, Arithmetic Operations of Hexadecimal Numbers, Floating Point
Numbers, Encoding Systems.
Module : VI
OPERATING SYSTEMS : Introduction, Custom-Made (Specification) Types of Operating Systems,
Computer Processing Techniques, Functions of Operting Systems Processor Management, Memory
Management, Virtual Storage, Device Management, Information Management.
Module : VII
INTERNET, ELECTRONIC – MAIL AND INTERNET : Informatkion Superhighway, Linking to
the Internet, Internet Address, Internet Tools, Domain Name System (DNS), Configuring Networks,
Configuring Dial-up Networking, Browsing Internet, Sending & Receiving Mail : MS – Outlook,
Intranet, Intranet vs. Groupware, Intranet Services, Communication Systems, Electronic Meeting
Systems.
APPLICATION OF INFORMATION TECHNOLOGY : Education and Training, Science and
Technology, Local Authorities and Public Utilities, Business and Industry.
TEXT BOOKS :
A. Jaiswal – Fundamentals of Computers & Information Technology, Dreamtech Publ., New Delhi,
2003.
BMLT 2009:HISTOLOGY
1. Introduction to histology and microtechnique
2. Fixation: Physical methods, chemical methods, General properties of fixatives, individual
fixative agents, choice of fixative, methods of fixation.
3. Processing and mounting: Processing, Keeping sections on slides, mounting media, treatments
before staining.
4. Dyes: Classification and nomenclature, histological staining, metachromasis and metachromatic
dyes.
5. Histological studies of circulatory system, alimentary system, digestive system, respiratory
system, urinary system, reproductive system, lymphatic and neurosensory system.
6. Staining blood and other cell suspension, connective tissue, nucleic acids, organic functional
groups and protein histochemistry, Carbohydrate and amyloid special staining procedures and
lipid staining.
7. Principles of metal impregnation techniques, Demonstration and identification of minerals and
pigments.
Books:
1.Kiernan JA: Histological and Histochemical Methods Theory and Practice., 3rd edn, Butter worth
& Heinemann Publication.
BMT2002 Human Anatomy & Physiology Lab.-II
Laboratory based on BMT2001 Human Anatomy & Physiology-II
Books Recommended:
1. Principles of Anatomy & Physiology: Tortora & Anagnodokos, Harper & Row publishers, N.Y.
2. Human Anatomy – Regional & Applied, Part-I, II & III: Chaurasia, CBS publisher &
Distributors, New Delhi.
3. Illustrated Physiology: McNaught & Callander, Churchill Livingstone.
4. Text book of Practical Physiology: Ranade, Pune Vidyarthi Griha Prakashan, Pune.
BMLT 2004: HEMATOLOGY LABORATORY I
1. Estimation of Hb by various methods.
2. Standardization of instruments for adaptation for Hb estimation.
3. Estimation of cell counts by both visual as well as electronic method
4. Estimation of leucocytes and platelets counts
5. Experiments based on study of morphology of normal blood cells and their identification
6. Estimation of erythrocytes sedimentation rate (ESR) by various procedures.
7.
Experiment based on routine examination of urine.
8. Experiment based on routine examination of biological fluids such as CSF
BOOKS:
1. Baker et al: An introduction to medical laboratory technology.
2. Charles F. Seiverd: Hematology for medical technologists
3. Arthur Simmons: Technical hematology
BMLT 2006 CLINICAL PATHOLOGY LABORATORY
1. Examination of urine analysis:
1. Physical examination: Volume, color, odor, appearance, specific gravity and pH
2. Chemical examination:
a. Protein: Heat and acetic acid test.
b. Sulfosalicylic acid method
c. Reducing sugar: Benedict test
d. Ketone bodies: Rothera test
e. Bile pigments: Fouchet method
f. Bile salt: Hays test
g. Blood: Benzidine test
h. Urobilinogen and Porphobilinogen: Ehrlich aldehyde and Schwartz test
2.Examination of stool:
1. Physical examination:
2. Chemical examination:
a. Occult blood
b. Reducing sugar
3. Microscopic examination of ova, cysts, crystals and fat globules
3. Examination of semen:
1. Physical examination:
2. Chemical examination:
4. Examination of CSF:
1.Physical examination:
2.Chemical examination:
5. Examination of Body fluids (pleural, pericardial and peritoneal):
1.Physical examination:
2.Chemical examination:
6. Examination of Synovial fluid:
1.Physical examination:
2.Chemical examination:
3. Microscopic examination
III Semester
Course No.
BMT 3001
BMT 3003
BMT 3005
BMT 3007
BMT 3009
Theory
Clinical Chemistry - II
Biomedical
Instrumentations
Digital Electronics System
Medical Microbiology
Instrumentation
&
Measurement System
Unit
1.0
1.0
Course No.
BMT 3002
BMT 3004
Laboratory
Unit
Clinical Chemistry Lab.-I 0.5
Instrumentation Lab.
0.5
1.0
1.0
1.0
BMT 3006
BMT 3008
SCA 3001
Digital Electronics Lab
Microbiology Lab.-I
PT & Games/CA
0.5
0.5
0.5
BMLT-3001: CLINICAL CHEMISTRY-II
Integration of Metabolism of Carbohydrates, Lipids and Proteins and Adaptation under Starvation
Metabolism of some Inorganic Constituents and water:
Sodium, Potassium and Chlorine, Calcium, Phosphorous, Iron, Magnesium, Iodine, Sulphur, Copper,
Zinc, Manganese, Cobalt, Molybdenum, Fluorine, Water balance
Energy Metabolism:
General Biochemical Aspects of Diet
Vitamins & Conenzymes
Prostaglandins,
Chemistry and Functions of Hormones
Mode of actions of hormones, Chemical nature of hormones, Pituitary hormones, Thyroid and
parathyroid hormones, Pancreatic hormones, Adrenal hormones, Gonadal hormones.
Porphyrins and Hemoglobins:
Porphyrins, Hemoglobins, Problems and adaptation at high altitudes.
Books Recommended:
1. Harper’s Review in Biochemistry: A.K. Murroy, D.K. Granner, P.A. Mayers and V.W. Rodwell:
Prentice Hall of India Ltd. New Delhi.
2. Fundamental of Clinical Chemistry R.W. Tietz (Ed.) W.B. Saunders Co., Philadelphia USA.
3. Clinical Chemistry (Principles and Techniques): R.J. Henry, D.C. Cannon, J.W. Winkelman:
Harper & Row Publishers.
4. Text Book of Biochemistry by Agarwal’s: Goel Publishing House.
5. A Text Book of Medicinal Biochemistry: R.L. Nath: New Age International Publishers.
6. Stryer: “Biochemistry,” 4th ed., W.H Freeman & company, 1995 (Reprint 1999).
7. Mussay et al.: “Harpers Biochemistry,” Prentice Hall International.
8. Marlin et al.: Harpers Biochemistry,” 24th ed., Lange Medical Publications, 1996.
9. Lehninger: “Biochemistry,” 3rd ed., Worth, CBS Publisher & Distributors 2000.
10. Conn & Stumpf: “Outline of Biochemistry,” 5th ed., John Wiley & Sons, 2003.
11. Harrow & Mazur: “Text book of Biochemistry,” W.B. Saunders, Philadelphia.
12. Jayaraman: “Laboratory Manual in Biochemistry,” Wiley Eastern Ltd., New Delhi.
13. Satyanarayan: “Biochemistry,” Book & Allied (P) Ltd., Reprint 2000.
Singh: “Practical manual of Biochemistry,” 4th ed., CBS Publishers & Distributors, 2001.
BMT – 3003 : BIOMEDICAL INSTRUMENTATION
Introduction to Biomedical Instrumentation : Types of measurements, factors in making measurement,
problem in measuring a living system.
(2)
Bio-signal equipment : ECG, EMG, EEG, Holter recorder, stores test and phonocardiography
(6)
Physiological Assist devices : pacemakers, defibrillators, nesthesia machine, mechanical ventilator, heart
lung machine, nerve and muscle simulator.
Pathological / Laboratory equipment : Principle and operation of cell counters and biochemical
analyzers, colorimeter, spectrophotometer, spectrofluorometer, pH meter, different types of ionic
electrodes, Elisa reader, glucometers.
(1)
Biomedical Imaging devices : Principle and operation of X-ray machine. CT-scan machine, Ultrasound
machine, MRI, Gamma Camera, SPECT, PET and endoscope.
(12)
Biomedical monitoring devices : Beside monitor, spirometer, pulse oximeter, sphygmomanometer and
pulmonary function analyzer.
(6)
Safety and Troubleshooting Risk factor, safety and management of biomedical equipment,
troubleshooting of common biomedical equipment and their rectification.
(4)
Books :
1.
2.
3.
4.
Introduction to Biomedical Technology by J.J. Karr & J.M. Brown
Handbook of Biomedical Instrumentation by R. S. Khandpur
Biomedical Instrumentation and Measurement by L. Crownwell et. Al.
Biomedical Instrumentation by M. Arumugham.
BMT-3005 : DIGITAL ELECTRONIC SYSTEMS
Module – 1
Introduction to Digital Systems, Number Systems, Binary Codes, Boolean Algebra – Basic definitions,
Basic Theorems and properties of Boolean Algebra, Boolean functions, Canonical and standard forms.
Module – 2
Digital Logic Gates – AND, OR, NOT, XOR, NAND, NOR and XNOR, IC Digital Logic
Families – RTL, DTL, TTL, MOS, CMOS and SSI, MSI, LSI, VLSI.
Module – 3
Simplification of Boolean functions – Types and their characteristics. Map method simplification for
two, three and four variables, NAND and NOR implementation.
Module – 4
Combinational Logic Circuits design procedure, Design of Adder, Subtractor and Code Converter.
Module – 5
Combinational logic circuit with MSI and LSI – Binary Parallel Adder, Decimal adder, Magnitude
comparator, Decoder Multiplexer, Encoder and De-multiplexer.
Module – 6
Introduction to Sequential Logic circuit, Flip-Flops – RS, JK T and D F/Fs. Triggering of Flip-Flops,
Concept of Counters and Registers, Ripple counters, Synchronous Counters, Ring Counter and Shift
Registers.
Module – 7
Introduction to Memory and Display Devices – their types and uses.
Books :
1.
2.
Digital logic and Computer Design by M. Moris Mano, TMH
Fundamentals of Digital logic with VHDL Design by Stephen Brown, Zvonko Vranesic,
TMH
Digital Integrated Electronics by Herbert Taub and Donald Schilling McGraw Hill.
BMT-3007 : MEDICAL MICROBIOLOGY
1. Introduction to microbiology: History of microbiology, role of microbiology in health and
diseases.
2. Instruments: Usage, care, handling and operation of various instruments including Microscope,
Incubator, Refrigerator, Hot air oven, centrifuge, autoclave, water bath, Platinum loop, Vacuum
pump, Electron Microscope, HEPA filter.
3. Sterilization: Principles and methods of sterilization, Physical, Chemical and Mechanical
methods of sterilization, Biological Indicators, Validation of various techniques of sterilization,
Sterilization of cotton, catgut, gauzes, solutions, media, milk, surgical and laboratory glass wares
etc.
4. Uses and mode of action of various disinfectants and antiseptics.
5. Bacteria: Cells, flagella, fimbriae, spores, capsule, mesosome, ribosome, nucleoid, plasmid and
transposable elements.
6. General methods of classification of bacteria: Autotropic and heterotropic bacteria, Eucaryotic
and prokaryotic cells, archeobacteria and their evolutionary concepts.
7. Procaryotes: Cyanobacteria, phototropic bacteria, spirochaetes, spiral curved bacteria, gram
negative aerobic rods and cocci , gram negative anaerobic rods, methane producing bacteria,
gram positive cocci, endospore forming rods and cocci, actinomycetes and related organisms and
rickettsias.
8. Bacterial Growth: Factors affecting growth, nutrition of bacteria, growth factors, respiration in
bacteria, microbial photosynthesis, methods determining bacterial growth, Bacterial growth
curve.
9. Cultivation of microorganism: Common culture and special media, anaerobic cultivation,
isolation and inoculation, maintenance and preservation of cultures, separation of pure cultures
from impure mixed cultures.
10. Staining methods: Gram staining, Acid fast staining, ZN staining, preparations of various stain
reagents and principles of staining methods.
11. Bacterial recombination: General principles, conjugation, transformation and transduction.
12. Fungi: Morphology and cultivation, cell structure, characteristic of fungal divisions, symbiotic
relationship of fungi.
13. Virus: Classification, general properties, cultivation and pathogenicity.
14. Human pathogenic microbes: Bacterial pathogens causing diseases in man with reference to
mode of infection of tuberculosis, diphtheria, meningitis, pneumonia, whooping cough; protozoa
causing diseases including Entameoba histolytica , Trichomonas vaginalis , Leishmania etc.
Books:
2. Introduction to Medical Microbiology by Anant Narayan.
3. Clinical Microbiology by Stokes & Ridgeway, Williams & Wilkins Publisher.
4. Pelczar , Chan & Kreig , Microbiology, 5th edn. , 1993.
5. Salle AJ, Fundamentals of Principles of Bacteriology.
6. Purohit, Microbiology,6th edn., 2002, Agrobios India
BMT – 3009 : INSTRUMENTATION AND MEASUREMENT SYSTEM
Introduction : Definition of measurement, Instrumentation, accuracy, sensitivity, precision resolution ,
types of errors, units and standards.
(3)
Analog Instruments : Moving coil and Moving iron instruments, Measurement of voltage, current and
power.
(5)
Bridge and their application : DC Bridge – Wheatstone and Kelvin’s bridge, AC Bridge – Maxwell’s
and Wein’s bridge.
(5)
Oscilloscope : CRT, Block diagram of oscilloscope, voltage and frequency measurement using
oscilloscope. Introduction to storage CRO
(9)
Transducers and their applications : Classification and selection of a transducer, Capacitive, inductive
and resistive transducers, strain gauge, gauge factor, Photo electric. Piezoelectric transducer and Hall
Effect transducers Measurement of temperature and pressure
(10)
Electronic Instruments : Introduction to Digital Voltmeter, transistorized voltmeter – cascade type and
bridge type
(4)
Display Devices and Recorders : LED, LCD, Magnetic tape recorder and X-Y plotter.
(4)
Books :
1. Modern Electronics Instrumentation and Measurement – Techniques W.D. Cooper &
A.D. Helfric, Pearson’s education publication.
Electrical & Electronics Measurement and Instrumentation – A. K. Sawhney, Dhanpatrai and son’s
publications.
BMLT-3002 : CLINICAL CHEMISTRY LABORATORY-I
1. To determine the titrable acidity of Urine,
2. To determine glucose content in Urine,
3. To determine calcium content in Urine,
4. To determine chloride content in Urine,
5. To determine creatinine content in Urine,
6. To determine creatine content in Urine,
7. To determine glucose in blood,
8. To determine cholesterol in blood,
9. To determine creatinine content in blood,
10. To determine calcium content in blood,
11. To determine urea content in blood,
12. To determine urea content in blood urine,
13. Protein estimation by Lowry’s Method,
14. Enzyme-linked immunosorbant assay (ELISA).
Books Recommended:
Varley’s Practical Clinical Biochemistry, Heireman Medical Books Ltd. London.
Hawsk’s Physiological Chemistry, Tata McGraw Hill Publishing Co.
Introduction to Practical Biochemistry by Plummer D.T. Tata McGraw Hill Publishing Co.
Clinical Chemistry in Diagnosis and treatment by E.J. Silva, P.R. Panral and Maryne: Edword
Arnold P.G. Publisher Ltd.
Microanalysis in Medical Biochemistry: Wooton I.D.P. and Freeman H.: Churchill Livingston,
Londan.
1.
2.
3.
4.
BMLT-3008 : MICROBIOLOGY LABORATORY - I
1. Introduction to use of laboratory instruments and safety precautions.
2. Collection, handling and storage of samples for diagnosis.
3. Uses of syringes, pipettes in microbiology laboratory.
4. Validation of autoclaves, hot air oven and other methods of sterilization etc.
5. Inoculation and incubation of liquid media.
6. Inoculation and incubation of solid media
7. Gram staining—Gram positive and gram negative
8. Acid fast staining
9.
Motility test
10. Measurement of growth of microorganisms.
11. Conjugation in bacteria
12. Transformation in bacteria
13. Transduction in bacteria
Books:
2. Mackie & McCartney, Practical Medical Microbiology.
3. Robert Feurst & W.B. Saundeu, Lab Manual & Workbook for Microbiology in Health &
Disease.
4. Gunasekharan , Laboratory Manual of Microbiology, New Age Publication
IV Semester
Course No.
BMT 4001
BMT 4003
BMT 4005
BMT 4007
BMT 4009
BMT 4011
BMT 4013
Theory
Applied Microbiology
Hematology – II
Histopathology
Parasitology & Cytology
Elective
Immunopathology
Or
Bio-signal acquition System
Elective
Intro. Microprocessor
Unit
1.0
1.0
1.0
1.0
Course No.
BMT 4002
BMT 4004
BMT 4006
BMT 4008
Laboratory
Microbiology Lab.-II
Hematology Lab.-II
Histopathology Lab.
Parasitology Lab
Unit
0.5
0.5
0.5
0.5
1.0
BMT 4012
or
.
Elective
Microprocessor Lab
PT & Games/CA
0.5
SCA 4001
0.5
BMT - 4001 : APPLIED MICROBIOLOGY
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
Preservation of industrial microbes and lyophilization.
Total and viable counts.
Testing of disinfectants: Rideal Walker test, Chick Martin test –their principles and methods
Immunology: Preparation and standardization of vaccines and sera with special reference to
BCG vaccine, polio vaccine, cholera vaccine, hepatitis vaccine, vaccine against mumps,
measles and rubella, various toxoids, Immunization Schedule
Sterility Testing of I/V fluids.
Lab diagnosis of common bacterial infections: Pyogenic infections, Respiratory tract
infections, Meningitis, Diphtheria, Whooping cough, Gas gangrene, Enteric fever, Diarrhoea
infections, Cholera, Urinary tract infections, Tuberculosis, Leprosy, Plague, Typhus fever,
Syphilis, Gonorrhoea etc.
Lab diagnosis of common fungal infections: Superficial dermatophyte fungal infections,
Candidiasis, Pulmonary infections, Eye and ear fungal infections.
Microbiology of food: Microorganism found in food, primary sources of food poisoning,
microbial examination of food, fungal toxin (mycotoxin) in food stuff, Preventive measures.
Microbiology of water: Biological characteristic of water, microorganisms in water,
microbiology of sewage, disinfections of water, treatment of waste water.
Microbiology of air: Introduction, methods of purification of air, testing of laboratory air.
Microbes in Fermentation Technology: General methods of production of enzymes,
alcohols, organic acids, antibiotic with reference to cellulose, asparaginase, ethanol, citric
acid, acetic acid, penicillin, streptomycin and tetracycline.
Brief introduction to advanced techniques in microbiology: RIA, CCIEP, Coagglutination, GLC, HPLC etc.
Books:
1.
2.
3.
4.
5.
6.
Pharmacopoeia of India, Published by Controller of Publication, New Delhi, 4th edn, 1996.
Berger’s Manual of Determinative bacteriology,
Hugo & Russell, Pharmaceutical Microbiology, Blackwell Scientific Publication, Oxford.
Stansbury PF & Whitakar A., Principles of Fermentation Technology, Pergamon Press.
Pelczar , Chan & Kreig , Microbiology, 5th edn. , 1993.
Stainer RY, Ingraham , General Microbiology, Wheeler & Painter.
BMT – 4003 : HEMATOLOGY II
1. Bone marrow aspiration, composition and function.
2. Staining of bone marrow smears and preparation of histopathological sections
3. Hemoglobin, synthesis, composition, function, degradation.
4. Hemoglobin pigments and their measurement
5. Abnormal hemoglobin and their means of identification.
6. LF cell phenomenon and various methods of demonstration.
7. Haemostatic mechanism, theories of blood coagulation, physicochemical properties of
coagulation factors, screening coagulation process, quantitative assay of coagulation factors.
BOOKS:
1. Baker et al: An introduction to medical laboratory technology.
2. Charles F. Seiverd: Hematology for medical technologists
3. Arthur Simmons: Technical hematology
4. Thomson J: Blood coagulation and homeostasis
BMT - 4005 : HISTOPATHOLOGY
1. Cell injury, cell death, cell adaptations, intracellular accumulations and cell aging, acute and
chronic inflammation, tissue repair, cell growth, fibrosis and wound healing, homodynamic
disorders, thrombosis, shock and neoplasia.
2. Histopathological techniques: Introduction to tissue preparation and processing including
fixation, dehydration, clearing and embedding
3. Decalcification and other process for bone.
4. Aspects of microtomy, cryotomy and theories of staining principles inclusive of routine and
special staining methods
5. Neuropathologic techniques
6. Electron microscope, working principles, components, allied techniques of electron microscopy.
7. Enzyme histochemistry, demonstration of phospatase, dehydrogenase, oxidase, peroxidase etc.
8. Biopsy
BOOKS:
1. Bancroft and Stevens: Theory and practice of histological techniques
2. Cullings: Cellular Pathology Techniques
BMT – 4007 : PARASITOLOGY AND CYTOLOGY
1. Protozoa: General characteristics, classification of protozoa of medical importance
2. General characteristics and classification of medical helminthology.
3. Morphology and life cycle, pathogenicity and laboratory diagnosis of intestinal protozoa
(amoeba –Giardia).
4. Morphology and life cycle, pathogenicity of various nematodes including Ascaris, Enterobious,
Strongyloides, Ancyclostome. Laboratory diagnosis of intestinal, tissue and blood nematode
infection
5. Morphology and life cycle, pathogenicity of cessode including Tanenia, H. nana, D. latum.
Laboratory diagnosis of cessode infections like hydatid, cysticerosis etc.
6. Morphology and life cycle, pathogenicity of various hemoflagellates including laboratory
diagnosis of infections caused by leishmania and trypanosomes.
7. Laboratory methods of collection, preservation and processing of samples for parasites in blood,
body fluids, stool, tissues and biopsy. Microscopic examination including preparation of stained
and unstained matter for parasites, concentration techniques and identification of various
parasites in collected samples.
8. Culture techniques of protozoa, helminthes, malaria, Entameoba histolytica.
9. Identification of different plasmodium species.
10. Important serological and immunological tests used in parasitology, Preparation and
standardization of various parasitic antigens and antisera and their standardization.
11. Cervical cytology- Basis of detection of malignant and premalignant lesion.
12. Hormonal assessment in cytological techniques and sex chromatin and pregnancy test.
13. Aspiration cytology principles, indication and utility of techniques with special emphasis on role
of cytotechniques in FNAC clinics.
BOOKS:
1.
2.
3.
4.
5.
Gold Smith: Tropical medicines & Parasitology, John Wright Publisher.
Roltt: Essential Immunology, ELBS Publisher.
Ash & Oriel: Parasites: A Guide to lab procedures & identification, Am. Soc. Clinical Publisher.
Halls & Sohantz: Immunodiagnosis of parasitic diseases, Academic Press.
N.C.Dey: Parasitology
BMT - 4009 : IMMUNOPATHOLOGY
1. An overview on the theory of blood groups; ABO groups and Rhesus systems; Clinical
significance of other blood groups;
2. Immunological aspects of blood transfusion;
3. Principles of blood grouping procedures and cross matching;
4. Blood collection, processing and storage;
5. Preparation of blood products; alloantibodies and complications of blood transfusion and
infections
6. Antenatal serology and hemolytic disease of the new born.
7. Allergy
8. Rheumatological diseases and investigation.
9. Cancer immunology.
10. Tissue typing for kidney transplant
Books Recommended:
1. Remingtons Pharmacecutical Sciences, 17th edn.
2. Stainer and Graham: General Microbiology, Wheelers & Painter.
3. Pharmacopoeia of India: Vol. I & II, 4th edn., 1996, Controls of Publication, Govt. of India.
4. Vyas & Dixit: Pharmaceutical Biotechnology, 1st edn., CBS Publisher, 1996.
5. Carters. Ed.: Coopers & Gumm’s Tutorial Pharmacy, 6th edn., CBS Publisher, 1972.
BMT – 4011 : BIO SIGNAL ACOUISITION SYSTEM
Generation of resting and action potential, polarization and depolarization, rhythmicity of cardiac
potential.
(5)
Definition of signals and noise, types of bio-signals and its sources.
(6)
Biomedical Sensors and electrodes, Transducers for biomedical application, Recording problems and its
remedy.
(9)
Different types of biomedical amplifiers and their principles of operation.
(5)
Radio telemetry system, Portable telemetry system, Land-line telemetry system, ECG and other
physiological telemetry system.
(5)
Different types of biorecorders, construction and principle of operation, different types of cameras used
for image recording systems and its processing.
(6)
Introduction to medical display systems, functional numerical display, central monitoring console,
principles of operation.
(4)
Books :
1.
2.
3.
Introduction to Biomedical Technology by J.J.Karr & J.M. Brown
Handbook of Biomedical Instrumentation by R.S. Khandpur
Biomedical Instrumentation and Measurement by L. Cromwell et.al.
BMT - 4013 : INTRODUCTION TO MICROPROCESSOR
Module – 1
Block diagram of Digital Computer, Introduction to Intel 8085 microprocessor, Components of a
microprocessor, Functional Block diagram of 8085, Pin description, Microcomputer system architecture,
Concept of machine cycle and instruction cycle.
Module – 2
Classification of Instruction on the basis of number of byte, Types of operation, and Addressing modes,
Instruction Description.
Module – 3
Introduction to Assembly Language Programming, Machine instruction, Assembler directives, Simple
programming examples like addition subtraction, multiplication, division, data transfer and
manipulation, code conversion, sorting etc.
Module – 4
Memory and I/O interfacing design, Input/Output Data Transfer techniques, Programmed I/O, DMA and
interrupt I/O.
Module – 5
Interfacing Chips – PPI 8255, PIT 8253 and Programmable Keyboard / Display Interface 8279 with
programming examples.
Module – 6
Introduction to Microcontroller, 8031/51 Microcongtroller architecture, External memory interfacing.
Instruction description, Programming examples based on medical applications.
Module – 7
Analog to Digital and Digital to Analog Converter, Interfacing of ADC808, DAC0808 with
microprocessor. The microprocessor in Biomedical Instrumentation, Computer analysis of the ECG,
Clinical Chemistry laboratory, Patient Monitoring, Computer Axial Tomography.
Books :
1.
2.
3.
4.
Microprocessor Architecture, Programming and Application with 8085 by R. S. Gaonkar
Microprocessor and Interfacing, Programming & Hardware by Douglas Hall.
The 8086, 8088 Microprocessors by A. K. Gautam & A. R. Jaiswal. S. K. Kataria & Sons
Biomedical Instrumentation and Measurements by Leslie Cromwell, Fred J. Weibell
BMT 4002 : MICROBIOLOGY LABORATORY II
1. Sterility Test
2. Viable count and Total count.
3. Antibiotic assay.
4. Isolation of pure culture from a mixed culture by various methods.
5. Rideal Walker test
6. Coliform Test
7. Tools for preservation of microbes including slant agar, lyophilization etc.
8. Alcohol fermentation by yeast.
9. Isolation and characterization of hemolytic streptococci
10. Isolation and characterization of intestinal pathogens.
11. Isolation and identification of Staphylococcus aureus, E. coli, Vibrio cholerae.
12. Toxin antitoxin assay.
Books:
1.
Oberhofer , Manual of Practical Medical Microbiology, Churchill & Livingstone Publisher.
2.
Pharmacopoeia of India, Published by Controller of Publication, New Delhi, 4th edn, 1996.
3.
Robert Feurst & W.B. Saundeu, Lab Manual & Workbook for Microbiology in Health &
Disease.
4.
Gunasekharan , Laboratory Manual of Microbiology, New Age Publication
BMT - 4004: HEMATOLOGY LABORATORY II
1. Determination of blood groups and Rh factors
2. Laboratory investigation of transfusion reaction
3. Staining of bone marrow smear and preparation of histopathological sections.
4. Experiments on identification and estimation of abnormal hemoglobin.
5. Quantitative assay of coagulation factors.
6. Various methods of demonstration of LF cell phenomenon.
7. Measurement of hemoglobin pigments
BOOKS:
1. Baker et al: An introduction to medical laboratory technology.
2. Charles F. Seiverd: Hematology for medical technologists
3. Arthur Simmons: Technical hematology
4. Thomson J: Blood coagulation and homeostasis
BMT – 4006 : HISTOPATHOLOGY LABORATORY I
1. Microscopy, maintenance and application of micrometry.
2. Handling of fresh histological specimens (tissues), frozen sections of fresh and fixed tissues.
3. Reception of specimen, dispatch of records, record keeping coding the lesson of cases.
4. Demonstration of cytoplasmic constituents.
5. Lipid identification and demonstration.
6. Demonstration of decalcification of calcified tissue before sectioning
7. Experiments based on enzyme histochemistry with special reference of demonstration of
various enzymes like phosphatase, dehydrogenase, oxidase and peroxidase
BOOKS:
1. Bancroft and Stevens: Theory and practice of histological techniques
2. Cullings: Cellular Pathology Techniques
BMT - 4008 : PARASITOLOGY LABORATORY
1. Introduction to operations of laboratory instruments and safety precautions.
2. Macroscopic examination of adult worms, cysts, tissues and processing of stool samples for
routine examinations.
3. Saline and iodine preparations for protozoal cysts and trophozoites.
4. Concentration procedures of protozoal cysts and trophozoites
5. Concentration procedures for helminthic ova and cysts.
6. Examination, identification of ova and cysts of medical importance.
7. Processing for preparation of antigens for Cason’s test and its interpretation.
8. Examination and processing of cysticerosis cysts.
9. Experiments based on serological and immunological tests used in parasitology
10. Differentiation of various mosquitoes, flies, worms etc.
11. Experiments based on electrophoretic techniques and gel diffusion
12. Preparation and standardization of various parasitic antigens and antisera.
Books:
1.Ash & Orinel: Parasites: A Guide to lab procedures & identification, Am. Soc. Clinical Publisher.
2.Halls & Sohantz: Immunodiagnosis of parasitic diseases, Academic Press.
3. Fleck & Moody: Diagnostic Techniques of medical parasitology, John Wright Publisher.
BMT – 4012 : MICROPROCESSOR LABORATORY
1.
Study of 8085 Microprocessor Kit.
2.
Write a program to add
(a) Two Hexadecimal Nos. 49H & 56H residing at location 2000H & 2001H and store
the result at 2050H.
(b) Two Hexadecimal Nos. that generate a carry
(c) Two Double byte Nos.
3.
WAP to add two Decimal Nos. 49D & 56D residing at location 2000H & 2001H. Subtract
62D from the result & store it in reg. B.
4.
WAP to store two 8-bit no. in Reg B & E. Multiply these numbers & store the result in
location 2501 & 2502.
5.
WAP to separate the Hexadecimal number into two nibbles (MSB and LSB nibbles) and
store the result in two different locations.
6.
Write a program to sort a list of 10 number in descending order.
7.
WAP to sort a list of 10 numbers in ascending order.
8.
WAP to convert a BCD no residing at 2400H into binary no. & store it at 2401H.
9.
WAP to convert a Binary no. residing at 2400H into a BCD no. and store it at 2500H.
10.
WAP to sort even and odd parity Bytes in such a way that odd parity bytes appear first &
even parity Bytes appear next. Keep a count of odd & even parity bytes in two successive
locations.
11.
16-bytes are residing in locations from 2400H. Write a Program to transfer these bytes in
locations starting from 2500H in such a way that first 8-bytes in the first Block should appear
at last 8-location of the 2nd block & the last 8-bytes in the first block should appear at first 8locations of the 2nd block.
V Semester
Course No.
Theory
Unit
Course No.
Laboratory
Unit
BMT 5001
Clinical Chemistry -III
1.0
BMT 5002
Clinical Chemistry Lab.-II
0.5
BMT 5003
BMT 5005
Forensic Medicine & Ethics
Material Management
1.0
1.0
BMT 5004
BMT 5006
Bacteriology Lab.
Histopathology Lab.-II
0.5
0.5
BMT 5007
BMT 5009
Serology & Virology Elective
Hemotology – III
1.0
1.0
BMT 5008
Serology & Virology Lab.
0.5
BMT 5011
or
Clinical Instrumentation
Biomedical imaging
devices & concept
BMT 5010
or
Hematology Lab.- III
or
Clinical Instrumentation
Lab.-II
BMT 5013
Elective
1.0
BMT 5012
0.5
Elective
0.5
BMT - 5001 : CLINICAL CHEMISTRY-III
Detoxication Mechanisms:
Types of Reactions in Detoxication
Functions of organs and their Tests:
Functions of Liver:
Tests based on secretary function of liver, Tests based on conjugation function of liver, Tests based on
Carbohydrate Metabolic function in liver, Tests based on Lipid Metabolic function in liver, Tests based
on Protein Metabolic function in liver, Tests based on Iron Metabolic function in liver.
Renal Functional Test :
Hormonal regulation of kidney function, Tests on the function of the upper G.I.T., Tests on the function
of the lower G.I.T., Thyroid Function Test,
Nutrition Dependent Disorders
Disorders related to Defects in Blood Coagulation
Antimetabolites
Antimetabolites in Cancer Therapy
Radioisotopes
Artificial Radioactive Isotopes, Tracer Technique, Application of Radioelements, Radiation Hazards and
safety measure.
Inborn Errors
Errors in Carbohydrate, Protein, Lipids, Amino acids and Nucleic acid metabolism.
Biochemical aspects of some special diseases:
HIV, Parkinsorism, Alzheimers/Thallasamia etc.
Books Recommended:
1. Harper’s Review in Biochemistry: A.K. Murroy, D.K. Granner, P.A. Mayers and V.W. Rodwell:
Prentice Hall of India Ltd. New Delhi.
2. Fundamental of Clinical Chemistry R.W. Tietz (Ed.) W.B. Saunders Co., Philadelphia USA.
3. Clinical Chemistry (Principles and Techniques): R.J. Henry, D.C. Cannon, J.W. Winkelman:
Harper & Row Publishers.
4. Text Book of Biochemistry by Agarwal’s: Goel Publishing House.
5. A Text Book of Medicinal Biochemistry: R.L. Nath: New Age International Publishers.
6. Stryer: “Biochemistry,” 4th ed., W.H Freeman & company, 1995 (Reprint 1999).
7. Mussay et al.: “Harpers Biochemistry,” Prentice Hall International.
8. Marlin et al.: Harpers Biochemistry,” 24th ed., Lange Medical Publications, 1996.
9. Lehninger: “Biochemistry,” 3rd ed., Worth, CBS Publisher & Distributors 2000.
10. Conn & Stumpf: “Outline of Biochemistry,” 5th ed., John Wiley & Sons, 2003.
11. Harrow & Mazur: “Text book of Biochemistry,” W.B. Saunders, Philadelphia.
12. Jayaraman: “Laboratory Manual in Biochemistry,” Wiley Eastern Ltd., New Delhi.
13. Satyanarayan: “Biochemistry,” Book & Allied (P) Ltd., Reprint 2000.
14. Singh: “Practical manual of Biochemistry,” 4th ed., CBS Publishers & Distributors, 2001.
BMT – 5003 : FORNSIC MEDICINE & ETHICS
1.
Legal and Ethical Aspects of Medicine and Laboratory.
2.
Forensic Medicine – Introduction.
3.
Setup of Forensic Science Laboratory.
4.
Forensic Examination of Biological Fluids, Steins, Trace Evidence and other Material.
5.
Drug Dependence and Abuse.
6.
Food Poison & Poisoning in general.
7.
Medico legal Aspects of MTP.
Books
1.
2.
Hand Book of Forensic Medicine & Toxicology by Dr. P.V. Chandha, Jay Pee Brothers, 85A, Karnala Nagar, Delhi – 110007.
Principle of Forensic Medicine by Apurba Nandy, New Central Book Agency (P) (Ltd.), 8/1,
Chintamani Das Lane, Calcutta – 9.
BMT – 5007 : SEROLOGY AND VIROLOGY
1. Immunity-Various types of immunity, antigen, antibody and their various applications in
diagnosis of diseases like diphtheria, tuberculosis etc.
2. Antigen Antibody reactions—Agglutination, precipitation, Flocculation, Neutralization,
Complement fixation reaction, principles and classification of various types of hypersensitivity
reactions.
3. Serological and immunological techniques used in diagnosis including Widal, VDRL,
Brucella agglutination, Cold agglutination, RA Test, CRP Tests, Paul Bennel Test, Gel Diffusion
Immunoelectrophoresis, Weil felix test etc.
4. Serological Tests used in virology like HA1, SRH, ELISA, RIA, IF, Immunoperoxidase, RPHA
etc.
5. Virology: Introduction to medical virology, Classification of viruses, General characteristics of
viruses including physical, chemical and biological properties; Collection, transport, processing
and storage of samples for viral diagnosis; Inoculation of fertile eggs by various routes and
techniques and their various incubation methods.
Books:
1. Timbery , Notes on Medical Virology(6 Vol), Churchill Livingstone Publisher.
2. Manual for rapid diagnosis in Virology, WHO Publisher
BMT – 5009 : HEMATOLOGY III
1. Definition and classification of anemia
2. Laboratory investigation procedures of megaloblastic anemia and iron deficiency anemia
3. Leukamia: definition and classification.
4. Cytochemical staining procedures in various haemopoietic disorders.
5. Laboratory techniques for assessing bleeding disorders.
6. Laboratory investigation of disseminated intravascular coagulation.
7. Mechanism of fibrinolysis: tests for fibrinolysis
8. Platelet functions and their interpretation.
9. Techniques available for cytogenic studies
10. Uses of radioisotopes in hematology., safety measures in handling radioisotopes
BOOKS:
1. Baker et al: An introduction to medical laboratory technology.
2. Charles F. Seiverd: Hematology for medical technologists
3. Arthur Simmons: Technical hematology
4. Thomson J: Blood coagulation and homeostasis
BMT – 5011 : CLINICAL INSTRUMENTATION
Clinical Cardiology: Electrocardiography, patient preparation for ECG recording, Electrode placement
of electrodes, distinguishing the artifacts in ECG recording and their removal.
(5)
Central monitoring system for intensive care unit, defibrillator and cardiac pacing, stress testing, Data
Acquisition techniques for electrophysiology.
(4)
Clinical electro-physiology : EEG, Different type of Machine and their electrical characteristics
placement of electrodes, different artifacts in EEG and their removal, Montages for EEG, types of
conducting paste for recording and their preparation, effects of different climatical conditions on
recording of EEG.
(8)
Electromyography, EMG, MNCV, SNCV, F.WAVE, DECREMENT, H.REFLEX, BLINK REFLEX,
VEP, BAER, SSEP test electrodes setup of machine and recording.
(5)
Clinical Psychiatrical Instrumentation – Electro shock therapy instrumentation, type of hazards and their
preventive measures, introduction to polygraph for monitoring of EMG, EEG, HR, Pulse, Respiration
Rate, Bio feed-back Instrument, Lie detector instrument.
(8)
Normal and Ambulatory blood pressure measurement, different types of diathermy, Orthopedic
diathermy-microwave, short wave diathermy ultrasonic diathermy, surgical diathermy and their different
electrodes for cutting and coagulation.
(7)
Dental arotors and different devices applied in dental clinics, Introduction to computerized opthalemic
instruction, A-mode ultrasonography.
(5)
Books :
1.
2.
3.
4.
5.
6.
Clinical Medicine, Praveen J. Kumar and Michaell Clark, “ELBS”.
Operating Manual of Neuroperfect, Medicaid Systems
Operating Manuals of ECG machine, TMT machine, Biofeedbacks machine, Diathermies
machine.
Introduction to Biomedical Technology by J.J. Karr & J.M. Brown.
Handbook of Biomedical Instrumentation by R.S. Khandpur.
Biomedical Instrumentation and Measurement by L. Cromwell et.al.
BMT – 5013 : BIOMEDICAL IMAGING DEVICES & CONCEPT
Imaging concept of living system, Image quality and its control, Introduction to different types of
contrast media in imaging procedures, indications of contrast reactions and its management.
(8)
X-ray : Different types of X-ray machines; concept of dose selection, (mAS), mA, kVp, parameter that
effect the quality of image, Different contrast used for x-ray and their methods of application.
(5)
Cassettes, screen, speed of film, types of grids and their application, collimeter, dark room and the film
processing, safety measure and prevention from radiation.
(5)
Ultrasound : Different modes of operations of ultrasound, ultrasonic probes and their selection for
different application, Gel, ultrasound gel automatic and semi automatic multiformat camera.
(8)
Computed Tomography : Concept of C.T. Machines and their description, patient preparation and
method of image capturing image storage devices, dry film concept, spiral and cardiac C.T.
(6)
Magnetic Resonance Imaging : Concept of MRI, type of magnets, charging of liquid helium and
charging of magnet, radio frequency interference and its prevention, installation of MRI, patient
preparation and selection of coil for various studies, contrast application and its hazard management.
(6)
Endoscopy : Different types of endoscopes, their principles and clinical applications.
(4)
Books :
1.
2.
3.
4.
5.
X-ray Diagnosis and Imaging by L.C. Gupta, Abhitabh Gupta; JAPEE Brothers Medical
Publisher (P) Ltd., Delhi.
Ultrasound Physics & Instrumentation, Davind Hykes, Wayne R. Hedrick, Dale
E.Starchman, Churchill Livingstone, N.Y.
Hand Book for X-ray Technician by Palmer, W.H.O. Publication.
Radiological Procedure by Chapman, Elsevier.
Handbook for Technicians : Darkroom Procedure by Palmar, W.H.O. Publication.
BMT : 5002 - CLINICAL CHEMISTRY LABORATORY-II
Analysis of Blood and Urine Enzymes:
1. Alkaline Phosphatase,
2. Acid Phosphatase,
3. Amylase,
4. Glutamate Oxaloacetate Transaminase (GOT).
5. Glutamate Pyrurate Transaminase (GPT).
6. Lipase,
7. Malate dyhydrogenase,
8. Nitrate and Nitrite reductase,
9. Ascorbic acid oxidase,
10. Catalase,
11. Peroxidase,
12. Lactate dehydrogenase,
13. Polyphenol oxidase,
14. Acetylcholine esterase,
Books Recommended :
Varley’s Practical Clinical Biochemistry, Heireman Medical Books Ltd. London.
Hawsk’s Physiological Chemistry, Tata McGraw Hill Publishing Co.
Introduction to Practical Biochemistry by Plummer D.T. Tata McGraw Hill Publishing Co.
Clinical Chemistry in Diagnosis and treatment by E.J. Silva, P.R. Panral and Maryne: Edword
Arnold P.G. Publisher Ltd.
5. Microanalysis in Medical Biochemistry: Wooton I.D.P. and Freeman H.: Churchill Livingston,
London.
1.
2.
3.
4.
BMT – 5004 : BACTERIOLOGY LABORATORY
1. Preparation of culture media.
2. Isolation of bacteria from various sources.
3. Steps in bacterial identification.
4. Biochemical reactions, tests & interpretation.
5. Cocci, Corynebacterium, Mycobacterium spp and their detailed identification.
6. Antibiotic sensitivity test.
Books:
1. Robert Feurst & W.B. Saundeu, Lab Manual & Workbook for Microbiology in Health &
Disease.
2. Gunasekharan , Laboratory Manual of Microbiology, New Age Publication
3. Berger’s Manual of Determinative bacteriology.
BMT – 5006 : HISTOPATHOLOGY LABORATORY II
1. Experiments based on processing of tissues for routine paraffin section and other methods of
embedding like cry out method.
2. Staining of histological section for connective tissue, muscle fibers, glycogen, RNA, DNA,
amyloid, lipid etc.
3. Interpretation of stained smear.
4. Demonstration of ferrous iron in tissue by Turnn blue reaction.
5. Experiments based on autopsy method and special test in post mortem examination by Lugol
iodine and haemosiderin.
6. Studies on tissues requiring special treatment like eye ball
BOOKS:
1. Bancroft and Stevens: Theory and practice of histological techniques
2. Cullings: Cellular Pathology Techniques.
BMT – 5008 : SEROLOGY AND VIROLOGY LABORATORY
1. Demonstration of staining technique: Preparation of the following stains and demonstration of
viral inclusion bodies: a) Seller’s Negri Body demonstration. b) Glemsa stain for Herpes viral
inclusion.
2. Preparation of reagents for serological tests: Phosphate buffer saline, Veronal buffered saline,
Dextrose gelatin, Veronal buffer and Tris buffer.
3. Principles and performance of viral heamagglutination and heamagglutination inhibition test.
4. Demonstration of Haemadsorption test.
5. Collection, titration and preservation of gunnipig serum for complement.
6. Demonstration of Complement fixation test.
7. Demonstration of ELISA for Hbs Ag detection.
8. Different staining techniques used in virology
9. Use of embryonated eggs in clinical virology.
10. Principles of animal cell culture and their use in virology.
11. Demonstration of immunofluorescence test and Immunoperoxidase test.
Books:
1.
2.
3.
Timbery , Notes on Medical Virology(6 Vol), Churchill Livingstone Publisher.
Manual for Rapid Diagnosis in Virology, WHO Publisher.
Robert Feurst & W.B. Saundeu, Lab Manual & Workbook for Microbiology in Health &
Disease.
BMT – 5010 : HEMATOLOGY LABORATORY III
1. Laboratory investigation procedures of megaloblastic anemia and iron deficiency anemia
2. Laboratory techniques for assessing bleeding disorders
3. Laboratory investigation of disseminated intravascular coagulation
4. Experiment based on laboratory techniques available for cytogenic studies
5. Experiment based on test for fibrinolysis.
6. Laboratory investigation of hemolytic anemia
7. Experiment based on Cytochemical staining process
8. Estimation of platelets in blood
BOOKS:
1. Baker et al: An introduction to medical laboratory technology.
2. Charles F. Seiverd: Hematology for medical technologists
3. Arthur Simmons: Technical hematology
4. Thomson J: Blood coagulation and homeostasis.