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887-0201 Rev. C i-STAT Acid-BAse Analysis Sales Aid_F.pdf 1 10/21/13 10:48 AM ® i-STAT 1 Guide Common Disease States Where Acid-Base Analysis Is Beneficial DIARRHEA RENAL FAILURE • Loss of sodium bicarbonate (Na+HCO3-) • Electrolyte abnormalities • Potential loss of free body water • Loss of sodium bicarbonate (Na+HCO3-) • Hydrogen (H+) retention • Electrolyte abnormalities • BUN and Creatinine (plus others) buildup and act as toxins • Lactate elevation with anemia DIABETIC KETOACIDOSIS VOMITING OR UPPER GI OBSTRUCTION (COMPLICATED DIABETES MELLITUS) • Ketoacids • Electrolyte abnormalities • Elevated anion gap • Loss of H+Cl- (hydrochloric acid) • Loss of K+ (usually K+Cl-) • Electrolyte abnormalities • Potential loss of free body water • Lactate elevation with gastric torsion (GDV) C M Y CM EXPECTED ACID-BASE ABNORMALITIES pH < 7.35 EXPECTED ACID-BASE ABNORMALITIES pH > 7.45 (DEPENDING ON SPECIES) (DEPENDING ON SPECIES) • Most common presentation in veterinary patients – metabolic acidosis • Metabolic alkalosis MY CY CMY K CARTRIDGE CHOICES CARTRIDGE CHOICES CG4+: Acid-base, lactate CG8+: Acid-base, HCT, electrolytes, acidosis often elevates iCa+ EC8+: Acid-base, HCT, electrolytes, best if high Anion Gap expected CG4+: Acid-base, lactate especially helpful with emergency or GDV CG8+: Acid-base, HCT, electrolytes, alkalosis can affect iCa+ EC8+: Acid-base, HCT, electrolytes (especially Cl-) FLUID THERAPY – COMMONLY USED • Normosol, Ringer’s and Lactated Ringer’s often best to correct acidosis ° Fluids without lactate indicated for elevated lactate levels or hepatic disease • Severe acidosis (i.e. pH < 7.25) consider bicarbonate therapy FLUID THERAPY – COMMONLY USED • Saline (Na+Cl-): 0.45% vs. 0.9% based on hydration status and electrolyte levels • K+Cl- supplementation common for vomiting patients (due to loss of K+) ° Low K+ dictates addition to fluids BETTER + BETTER 887-0201 Rev. C i-STAT Acid-Base Analysis Sales Aid_B.pdf 1 10/21/13 10:48 AM i-STAT 1 Pricing System A tiered pricing system is an effective tool for compliance, which leads to better medicine and increased ancillary diagnostics, additional treatments and medications. CARTRIDGE CHOICES FOR ACID-BASE ANALYSIS CG4+ CG8+ EC8+ $15.20 $15.85 $16.00 pH pH pH PCO2 PCO2 PCO2 HCO3 HCO3 HCO3 TCO2 TCO2 TCO2 base excess base excess base excess PO2 PO2 anion gap sO2 sO2 Hct lactate Hct Hgb Hgb Glu Glu BUN iCa Na, K Na, K Cl C M Y CM MY CY CMY K TEST - CG4+ EXAMPLE PRICE PROFIT With Diagnostic Panel – Routine Illness $30.00 $14.80 In-hospital monitoring $35.00 $19.80 Re-check without panel $40.00 $24.80 Critical Patient $50.00 $34.80 800.822.2947 www.abaxis.com/veterinary [email protected] Abaxis, Inc. Worldwide Headquarters 3240 Whipple Road Union City, CA 94587 Tel 800 822 2947 Fax 510 441 6150 BETTER + BETTER. Abaxis and VetScan are registered trademarks of Abaxis, Inc. i-STAT is a registered trademark of the Abbott Group of Companies in various jurisdictions. © Abaxis 2013 887-0201 Rev. C www.abaxis.com