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● 97 年 8 月 1 日起聘之特聘教授之推薦理由、五年內著作與 RPI 資料: 生物科技學研究所王敏盈教授: 推 薦 理 由 1. 最近十年內獲國科會年度專題計畫研究主持費達九次,內含八十七及八十九 年度兩次甲等獎。 § 最近五年著作目錄一覽表 § 最 作者 Min-Ying Wang, Hui-Ling Hu, Shing-Yi Suen, 近 Fang-Yi Chiu, Jui-Hung Shien, and Su-Yuan Lai* 五 年 著 作 目 錄 1 著作名稱 出版處所或 期刊卷期 出版時間 期刊論文 備註 期刊名稱 (頁次) 年/月 影響係數 Veterinary In press 2008 2.073 SCI Microbiology “Development of an Enzyme-linked Immunosorbent Assay for Detecting Infectious Bursal Disease Virus (IBDV) Infection Based on the VP3 Structural Protein.” Doong, Shyue-Ru; "A Strong and Analytical Chen, Yi-Huei; Heterogeneous Adsorption Chemistry. Lai, Su-Yuan; Lee, of Infectious Bursal Cheng-Chung; Disease VP2 Subviral Lin, Yu-Chiang; Particle with Immobilized Min-Ying Wang* Metal Ions Depends on Two Surface Histidine Residues" Ta-Wei Lin, Chicken Heat Shock Journal of Chi-Wen Lo, Protein 90 Is a Component Virology. Su-Yuan Lai, of the Putative Cellular Ruey-Jane Fan, Receptor Complex of Chao-Jung Lo, Infectious Bursal Disease Yu-mei Chou, Virus Rekha Thiruvengadam, Andrew H.-J. Wang Min-Ying Wang* Cheng-Chung Lee, Crystal structure of Journal of Tzu-Ping Ko, infectious bursal disease Structural Chia-Cheng Chou, virus VP2 subviral particle Biology. Masato at 2.6 Å resolution: Yoshimura, implications on virion Shyue-Ru Doong, assembly and *Min-Ying Wang, immunogenicity Andrew H.-J. Wang 79:7654-7 2007/10 5.646 661. SCI 81:8730-8 2007/8 741. 5.341 SCI 155:74-86. 2006/7 3.496 SCI Hui-Ling Hu, Min-Ying Wang, Chiung-Hsuah Chung, Shing-Yi Suen Purification of VP3 protein of Infectious Bursal Disease Virus Using Nickel Ion-Immobilized Regenerated Cellulose-Based Membranes Meng-Shiou Lee, Processing of Infectious Jin-Yi Ho, Bursal Disease Virus Su-Yuan Lai, (IBDV) and Shyue-Ru Doong, self-assemblies of and *Min-Ying IBDV-like Particles in Wang Hi-5 Cells Chien-Shiuh Chen, Purification of Capsid-like Shing-Yi Suen, Particles of Infectious Su-Yuan Lai, Gary Bursal Disease Virus Ro-Lin Chang, (IBDV) VP2 Expressed in Tsung-Chi Lu, E. coli with a Metal-ion Meng-Shiou Lee, Affinity Membrane and *Min-Ying System. Wang Meng-Shiou Lee, Characterization of Min-Ying Wang, particles formed by the Yu-Jui Tai, and precursor protein VPX of Su-Yuan Lai infectious bursal disease virus in insect Hi-5 cells: implication on its proteolytic processing Lee, C.-C., Ko, Purification, T.-P., Lee, M.-S., Crystallization, and Chou, C.-C., Lai, Preliminary X-ray S.-Y., Wang, A. Analysis of Immunogenic H.-J. and *Wang, Virus-Like Particles M.-Y. Formed by Infectious Bursal Disease Virus (IBDV) Structural Protein VP2 Tsai, Y.-H., Wang, Purification of Hepatocyte M.-Y., Suen, S.-Y. Growth Factor Using PVDF-Based Immobilized Metal Affinity Membranes – Equilibrium Adsorption Study 2 Journal of 840:76-84. 2006/8 Chromatogra phy B. 2.647 SCI Biotechnolog 22:763-76 2006/6 y Progress. 9. 2.102 SCI Journal of Virological Methods. 130:51-58. 2005/12 2.097 SCI Journal of Virological Methods. 121:191-1 2004/9 99. 2.097 SCI Acta 2003/7 59: Crystallograp 1234-1237 hica Section D Biological Crystallograp hy 2.008 SCI Journal of 766:133-1 2002/1 Chromatogra 43 phy B: Biomedical Sciences & Applications. 1.687 SCI § 研究人員研究表現指數(RPI)統計表 B § 姓名:王敏盈 (修正:2008//05/19) 系所:生物科技學研究所 研究年資(請打):■滿 5 年以上(選最佳 10 篇) □滿 3 年(選最佳 5 篇) □滿 4 年(選最佳 7 篇) □未滿 3 年(選最佳 3 篇) 五年內(2003.1.1 迄今)代表性研究成果名稱 研究 成果 序號 分類 代碼 1 6 2 7 1 3 1 4 1 5 1 6 1 7 1 8 1 9 3 論文性 1. 學術論文必須填寫所有作者(按期刊之原排序)、著作名稱、期刊名稱、 質分類 加權分 年份、卷期、起迄頁數。 數 2. 專利必須填寫專利名稱、發明人、證書號碼、國別、專利期間。 (C) 3. 技術移轉必須填寫技術名稱、技轉金額及對象、年份。 禽類華氏囊病毒感染性次單位元之製備及利用其之疫苗及診斷試劑,發 明人:王敏盈等,中華民國專利,專利號碼:I 233947,專利期限: 2005~2022。 刊登雜 誌分類 排名加 權分數 (J) 作者 排名 加權 分數 (A) C×J×A S01 40 S02 技術名稱:以 8 公升震盪瓶培養昆蟲細胞生產重組蛋白。移轉廠商:宏 億生物科技公司。技術發明人:王敏盈,董學儒 Lee, C.-C., Ko, T.-P., Lee, M.-S., Chou, C.-C., Lai, S.-Y., Wang, A. H.-J. and *Wang, M.-Y., 2003. “Purification, Crystallization, and Preliminary X-ray Analysis of Immunogenic Virus-Like Particles Formed by Infectious Bursal Disease Virus (IBDV) Structural Protein VP2” Acta Crystallographica Section D Biological Crystallography 59: 1234-1237. Min-Ying Wang, Hui-Ling Hu, Shing-Yi Suen, Fang-Yi Chiu, Jui-Hung Shien, and Su-Yuan Lai*, 2008. “Development of an Enzyme-linked Immunosorbent Assay for Detecting Infectious Bursal Disease Virus (IBDV) Infection Based on the VP3 Structural Protein.” Veterinary Microbiology (in press). (SCI, Impact factor (2006): 2.073,VETERINARY SCIENCES, 4/129) Lai, S.-Y., Chen, H.-C., Lee, M.-S., Jinn, T.-R., Kao, S.-S. and *Wang, M.-Y., 2004. “Production and Purification of Immunogenic Virus-Like Particles by the Infectious Bursal Disease Virus Structural Protein, rVP2H, in Insect Larvae” Process Biochemistry 39:571-577. (SCI, , Impact factor (2006): 2.008, Engineering, chemical, 10/110) Chien-Shiuh Chen, Shing-Yi Suen, Su-Yuan Lai, Gary Ro-Lin Chang, Tsung-Chi Lu, Meng-Shiou Lee, and *Min-Ying Wang, 2005. “Purification of Capsid-like Particles of Infectious Bursal Disease Virus (IBDV) VP2 Expressed in E. coli with a Metal-ion Affinity Membrane System.” Journal of Virological Methods 130:51-58. (SCI, Impact factor (2006): 2.097, Biotechnology&Applied Microbiology, 58/140) Doong, Shyue-Ru; Chen, Yi-Huei; Lai, Su-Yuan; Lee, Cheng-Chung; Lin, Yu-Chiang; Min-Ying Wang*, 2007. "A Strong and Heterogeneous Adsorption of Infectious Bursal Disease VP2 Subviral Particle with Immobilized Metal Ions Depends on Two Surface Histidine Residues" Analytical Chemistry. 79:7654-7661. (SCI, Impact factor (2006): 5.646, Chemistry analytical 1/68). Ta-Wei Lin, Chi-Wen Lo, Su-Yuan Lai, Ruey-Jane Fan, Chao-Jung Lo, Yu-mei Chou, Rekha Thiruvengadam, Andrew H.-J. Wang and Min-Ying Wang*, 2007. “Chicken Heat Shock Protein 90 Is a Component of the Putative Cellular Receptor Complex of Infectious Bursal Disease Virus” Journal of Virology. 81:8730-8741. (SCI, Impact factor (2006): 5.341, Virology 4/23). Meng-Shiou Lee, Jin-Yi Ho, Su-Yuan Lai, Shyue-Ru Doong, and *Min-Ying Wang, 2006. “Processing of Infectious Bursal Disease Virus (IBDV) and self-assemblies of IBDV-like Particles in Hi-5 Cells.” Biotechnology Progress 22:763-769. (SCI, Impact factor (2006): 2.102, Food Science&Technology, 14/96) 分數 70 S03 3 4 5 60 S04 3 5 5 3 5 5 3 3 5 3 5.646 5 3 5.341 5 S08 3 5 5 S09 36 S05 75 S06 45 S07 84.69 80. 115 75 1 10 Cheng-Chung Lee, Tzu-Ping Ko, Chia-Cheng Chou, Masato Yoshimura, Shyue-Ru Doong, *Min-Ying Wang, and Andrew H.-J. Wang, 2006. “Crystal structure of infectious bursal disease virus VP2 subviral particle at 2.6 Å resolution: implications on virion assembly and immunogenicity” Journal of Structural Biology 155:74-86. (SCI, , Impact factor (2006): 3.496, BIOPHYSICS, 15/66) 積 分 3 4 5 S10 60 S11 (S11=S01+S02+S03+........+S10) 研究表現指數(RPI)【(積分×100)/指標上限滿分= (S11×100)/指標上限滿分】 664.8 88.64 註 1:已被接受但未出刊之論文需附接受函或相關證明文件,技術移轉需附上合約書,專利需附上專利證 書,前述文件請掃描附於本表之後一併上傳,未附者將不採計。 註 2:「刊登雜誌分類排名」以 Journal Citation Report (JCR) 最新年度版本之 SCI 及 SSCI 期刊資料為準。 附註:著作如屬 SCI、EI、SSCI 等,請註記於「備註欄」。 4