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Chapter 12 – the heart 4 chambers – which act as 2 pumps for pulmonary circulation and systemic circulation See diagrams pp. 324- 329 Location – thoracic cavity between the lungs, within the mediastinum Apex – most inferior portion Base – superior portion Heart anatomy diagram Go here for the best diagrams all kinds of wonderful information on the heart! External anatomy Coronary sulcus Superior and inferior vena cava Pulmonary veins Pulmonary trunk Aorta Membranes: pericardial cavity, pericardium: fibrous, serous, parietal, visceral, pericardial fluid Blood supply to the heart Coronary arteries (left and right) Cardiac veins Coronary sinus Heart chambers Atria – right and left Auricle Interatrial septum Ventricles – right and left Interventricular septum Heart valves Atrioventricular valves Tricuspid valve – between right atrium and right ventricle Bicuspid (mitral) valve – between left atrium and laft ventricle Papillary muscles Chordae tendineae Aortic and pulmonary semilunar valves Blood flow through the heart Both atria contract at the same time and both ventricles contract at the same time Body vena cava right atrium tricuspid valve right ventricle pulmonary semilunar valve pulmonary arteries lungs pulmonary veins left atrium bicuspid valve left ventricle aortic semilunar valve aorta body Heart wall Three layers: Epicardium Myocardium endocardium Cardiac muscle Striated Elongated, branching cells 1 or 2 nuclei Rich in mitochondria ATP Intercalated disks Conduction system of the heart SA node AV node AV bundle Left and right bundle branches Purkinje fibers See diagram pg. 336 Ectopic beat electrocardiogram P wave QRS complex T wave P-Q interval P-R interval Q-T interval electrocardiogram Cardiac cycle Systole – atrial and ventricular – contraction Diastole – atrial and ventricular – relaxation Heart sounds – stethoscope Murmurs Incompetent valve Stenosed opening Regulation of heart function Cardiac output Stroke volume Heart rate Cardiac output = stroke volume x heart rate Intrinsic regulation Regulation mechanisms contained within the heart Venous return Preload Starling’s law of the heart afterload Extrinsic regulation Regulation by factors outside the heart – nervous and hormonal regulation Baroreceptor reflex Medulla oblongata – cardioregulatory center