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Supplementary MBBS II (Second) Professional Examination 2014-15 Course Code:MBS203 Paper ID:S322412 Pharmacology-II Time: 2 Hours 40 Minutes Max Marks: 30 Note: Attempt all questions. Draw proper diagrams to support your answer. Part ‘B’ 1. Enumerate anti-hypertensive drugs. uses and adverse effects of Ramipril. 2. Classify anti-thyroid drugs and discuss propylthiouracil in detail. (7) 3. Describe important (7) Write mechanism of action of: Azithromycin Metformin Parenteral iron therapy Urokinase (2x4=8) a) b) c) d) (2x4=8) a) b) c) d) Write short notes on the followings: Potassium channel openers Spironolactone Bisphosphonates Digoxin toxicity 4. Supplementary MBBS II (Second) Professional Examination 2014-15 Roll No. Student’s Name Student’s Signature Invigilator’s Signature Course Code:MBS203 Paper ID:S322412 Pharmacology-II Part ‘A’ Time: 20 Minutes Max Marks: 10 Note: 1. Attempt all questions and return this part of the question paper to the invigilator after 20 Minutes. 2. Please tick (√) correct one only. Cutting, overwriting or any other marking are not allowed. 3. For answering please use Ball- pen only. Q.1 Q.2 Q.3 Q.4. Q.5 Following are the L type Ca+ channel blockers except: a) Flunarizine b) Nifedipine c) Verapamil d) Diltiazem Q.6 Following is the K+ channel opener: a. Nicorandil b. Minoxidil c. Diazoxide d. All of the above Q.7 Following drug is not preferred for hypertensive emergency: a) Atenolol b) Diazoxide c) Sodium nitroprusside d) Minoxidil Following one is preferred drug for P. Vivax malarial fever (Relapsing fever): a) Chloroquine b) Primaquine c) Artimisinin d) Quinine Q.8 Following one is not preferred in P. aeroginosa induced UTI: a) Cotrimoxazole b) Gentamicin c) Carbencillin d) Ciprofloxacin Q.9 Jarisch-herxheimer reaction is associated with: a) Ornidazole b) Tinidazole c) Metronidazole d) Penicillin Following one is mild diuretics: a) Acetazolamide b) Thiazide c) Furosemide d) Metolazone Antidote of Heparin is: a) Protamine sulfate b) Vit. K c) Epsilon amino caproic acid d) Tranexamic acid Antidote of streptokinase: a) Protamine sulfate b) Vit. K c) Epsilon amino caproic acid d) Ticlopidine P.T.O Q.10 Following 1st line anti tubercular drug is given only for intensive phase: a) Pyrazinamide b) Ethambutal c) Isoniazid d Rifampicin Q.18 Glucocorticoids are used in all of the following conditions except: a) Rheumatoid arthritis b) Nephrotic syndrome c) Anaphylaxis d) Hespes simplex keratitis Q.11 Following one drug is not standard RNTCP regimen for MDR TB: a) Kanamycin b) Levofloxacin c) Pyrazinamide d) Isoniazid Q.19 The drug which inhibits the conversion of cholesterol in to pregnonolane is: a) Ketoconazole b) Metyrapone c) Aminogluthemide d) Mitotane Q.12 Tetracycline is still drug of choice in the following condition: a) Plague b) UTI c) Respiratory tract infection d) All of the above Q.20 Following one of the vitamin acts as hormone: a) Vit A b) Vit C c) Vit K d) Vit D Q.13 Flu like syndrome is common adverse effect with the following: a) Pyrazinamide b) Streptomycin c) Rifampicin d) Isoniazid Q.14 The drug of choice for the treatment of methicillin resistance s. aureus infection is: a) Tetracycline b) Vancomycin c) Amikacin d) Erythromycin Q.15 Preferred oral hypoglycemic drug for diabetes type II with obesity is: a) Glipizide b) Metformin c) Pioglitazone d) Acarbose Q.16 Following are the use of Mifepristone: a) Termination of pregnancy b) Post coital contraceptives c) Cervical ripening d) All of above Q.17 For the post partum hemorrhage following drug is preferred: a) Oxytocin b) Ergometrine c) Ergotamine d) All of the above