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Functions of the Urinary System Elimination of waste products Nitrogenous wastes (urea, uric acid, creatinine) Toxins Drugs Regulate aspects of homeostasis Water & electrolyte balance Acid-base balance in the blood Blood pressure (enzyme renin) Red blood cell production (hormone erythropoietin) Activation of vitamin D Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Organs of the Urinary System Kidneys Produce urine Ureters Tubes that transport urine from kidneys to bladder Urinary bladder Muscular sac that stores urine until export from the body Urethra Tube that carries urine from bladder to body exterior by peristalsis Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Organs of the Urinary System Figure 15.1a Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Organs of the Urinary System Figure 15.1b Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Location of the Kidneys Against the dorsal body wall At the level of the T12 to L3 vertebrae The right kidney is slightly lower than the left (due to position of the liver) Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Kidney Features Renal hilum A medial indentation where several structures enter or exit the kidney (ureters, renal blood vessels, and nerves) An adrenal gland sits atop each kidney Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Organs of the Urinary System Figure 15.1a Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Coverings of the Kidneys Renal Capsule Fibrous tissue Surrounds each kidney Perirenal Fat Capsule Fatty mass that surrounds each kidney to protect it from blows Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Regions of the Kidney Renal cortex—outer region Renal medulla—inside the cortex Contains funnel-shaped structures called renal pyramids Pyramids separated by renal columns (cortexlike tissue) Renal pelvis—inner collecting tube Pouch that narrows & extends into the ureter Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Regions of the Kidney Figure 15.2b Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Nephrons The structural and functional units of the kidneys Responsible for forming urine Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Urine Formation Glomerular filtration Tubular reabsorption Tubular secretion Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Tubular Reabsorption The peritubular capillaries reabsorb useful substances back into blood: Water Glucose Amino acids Ions Some reabsorption is passive, most is active Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Tubular Reabsorption Materials not reabsorbed Nitrogenous waste products Urea—protein breakdown Uric acid—nucleic acid breakdown Creatinine—associated with creatine metabolism in muscles Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Pathway of Urine Urine is continuously made in the kidneys Travels down the ureters by peristalsis Enters the urinary bladder where it is stored Eventually sent out of the body via the urethra 8 inches long in males 1.5 inches long in females Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Urinary Bladder Capacity A moderately full bladder is about 5 inches long and holds about 500 mL of urine Capable of holding twice that amount of urine Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Position and Shape of a Distended and an Empty Urinary Bladder in an Adult Man Figure 15.7 Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Characteristics of Urine In 24 hours, about 1.0 to 1.8 liters of urine are produced Yellow color due to the pigment urochrome (from the destruction of hemoglobin) and solutes Sterile Slightly aromatic Normal pH of around 6 Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Characteristics of Urine Solutes normally found in urine: Sodium and potassium ions Urea, uric acid, creatinine Ammonia Bicarbonate ions Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Characteristics of Urine Solutes NOT normally found in urine: Glucose Blood proteins Red blood cells Hemoglobin White blood cells (pus) Bile Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Abnormal Urine Constituents Table 15.1 Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings