Download Exams 1,2,3 (drop one) 70%

Chem 21000, Section P, Code 0427
CHEMISTRY 21000 – Syllabus
Applied Chemistry for Biomedical Engineers
(a.k.a. Organic and Biochemistry for Biomedical Engineers)
Fall 2009
Instructor: Prof. Kevin Ryan Office MR-1337 (212) 650-8132 [email protected]
Office Hours: Tuesdays 3:15-4:45; Wednesdays 10:40 AM – 11:50.
Class time: Tuesdays and Thursdays from 2:00-3:15 pm.
Room:
Marshak 1307 (Please take into account the slow elevators)
Textbook: General, Organic and Biochemistry, 6th Edition, Denniston, Topping and Caret McGrawHill (available in the bookstore and on the internet)
This course is intended to introduce biomedical engineering majors to key concepts in organic
chemistry and biochemistry, and to describe the significant connections between these topics and
health, disease and the molecular treatment of disease. The course will balance theoretical and
practical chemistry, while emphasizing material that is relevant to health-related studies. The material
will be taught at a level intended for students whose professional goals do not include a mastery of
chemistry, but for whom an understanding of the principles of chemistry and their practical
applications is a necessity. The pre-requisite for this course is Chem 10401 (with a minimum grade of
C); engineering majors only.
How to maximize your chances for an A: Read the chapter carefully before class. Attend class. Reread the chapter after class. Be able to do and understand all of the problems at end of the chapter.
Strive to understand both the concepts and the details.
Grading
Exams 1,2,3 (drop one)
Unannounced Quizzes
Final Exam
TOTAL
70%
5%
25%
100%
There will be three 75-minute exams, and you must take at least two. If you take all three exams your
lowest score will be dropped. If you take only two regular exams, they will both count towards your
grade. Do not skip exam 1 or 2 unless you are ill. A make-up exam will be given only if you are absent
for a verifiable medical reason for two exams. All instructional activities are planned for working days
during class hours as indicated by City College. The exams taken will contribute 70% to your final
grade. The comprehensive final exam will contribute 25%. Unannounced quizzes and, to a lesser
extent, class participation will account for the remaining 5%. Repeated classroom interruptions by a
cell phone or other electronic device will lead to deduction of points from the final grade at a rate to be
determined. (So please turn them off or set them to vibrate).
Chem 21000, Section P, Code 0427
****Calendar for Fall 2009****
Tuesdays 2-3:15 PM
Thursdays 2-3:15 PM
September 1 Ch. 10
September 3 Ch. 10
September 8 Ch. 11
September 10 Ch. 11
September 15 Ch. 12
September 17 Ch. 12
September 22 Ch. 13
September 24 Ch. 13
September 29 No class Monday Schedule
October 1
EXAM 1 (Ch 10-13)
October 6
Ch. 14
October 8
Ch. 14
October 13
Ch. 15
October 15
Ch. 15
October 20
Ch. 16
October 22
Ch. 16
October 27
Ch. 17
October 29
Ch. 17
November 3 Ch. 18
November 5 EXAM 2 (Ch 14-17)
November 10 Ch. 18
November 12 Ch. 19
November 17 Ch. 19
November 19 Ch. 20
November 24 Ch. 20
November 26 Thanksgiving
December 1 Ch. 21 (21.1-21.4)
December 3 Ch. 22 (22.1-22.4)
December 8 Ch. 22 (22.6) and 23.1-23.2 December 10 EXAM 3 Nov 3 thru Dec 3
Date TBA: Comprehensive Final Exam
Please note, the last day for “W” grade is November 6.
Blackboard will be used. Please check frequently. Please also make sure that your correct email
address is registered with blackboard through CUNY Portal.
A tip for understanding organic chemistry and biochemistry:
Like everyday macroscopic objects, molecules have 3-dimensional structures that determine their
properties:
Stereo projection of codeine
To view: Hold page in front of you, but focus your eyes on the horizon beyond the
page. Then, without refocusing, look at the projection.
OR
While looking at the projection, relax your eye coordination as if you were tired. One
image will drift into the other.
OR
Use a stereoviewer
Chem 21000, Section P, Code 0427
Academic Integrity: The CCNY policy on academic integrity will be followed. Document is posted on the CCNY website
(CUNY policy on academic integrity—link is at the bottom of the home page). Make sure you have read the details
regarding plagiarism and cheating, in case you are not clear about the rules of the college. Cases where academic integrity
is compromised will be prosecuted according to these rules.
***********************************************************************************************************
Official Learning Outcomes for Chemistry 21000
After completing this course, students should be able to:
1. Understand and explain the common structural motifs found in
carbonaceous compounds, including carbon allotropes.
2. Understand and explain chemical bonding in organic molecules,
including the distinction between covalent and non-covalent bonding,
and between single and multiple bonds.
3. Understand and explain simple physico-chemical trends in a
homologous series of organic compounds, such as the boiling or
melting points of the linear alkanes or alcohols.
4. Understand and draw models of conformational isomers of linear
and cyclic alkanes.
5. Recognize and predict simple physico-chemical properties of the
common organic functional groups based on their structure-based noncovalent interactions.
6. Write balanced chemical reactions for the most basic reactions
characteristic of the common organic functional groups, such as
alkenes, alcohols, aldehydes, ketones, carboxylic acids, esters, amines
and amides.
7. Plan a short chemical synthesis of monofunctional compounds
containing the major functional groups listed above.
8. Understand the relationship between polymer molecular structure
and the fundamental physical properties of polymeric materials.
9. Understand acid-base equilibria of amino acids as described by the
pKa.
10. Distinguish between primary, secondary, tertiary and quaternary
structures in biopolymers.
11. Analyze the reaction coordinate for an enzyme catalyzed metabolic
reaction.
12. Explain using a diagram the Central Dogma of Molecular Biology.
13. Understand and explain how cells burn organic molecules and trap
some of the energy in the chemical bonds of ATP
14. Follow a specific glucose carbon through glycolysis.
15. Follow a specific Acetyl-CoA carbon through the Krebs Cycle.
16. Follow a specific fatty acid carbon through beta oxidation
17. Qualitatively describe Oxidative Phosphorylation and explain why
aerobic organisms require oxygen to live.
Dept.
Outcome
letters
a
a
a,d
a
a,d
a
a
a
a,b,e
a,b
a,b,d
a,b
a,b,e
a,b
a,b
a,b
a,b
Chem 21000, Section P, Code 0427
Topics covered:
Saturated Hydrocarbons
Unsaturated Hydrocarbons
Alcohols, Phenols, Thiols and Ethers
Aldehydes and Ketones
Carboxylic Acids and Derivatives
Amines and Amides
Carbohydrates
Lipids
Protein Structure and Function
Enzymes
Introduction to Molecular Genetics
Carbohydrate Metabolism
Aerobic Respiration and Energy
Production
Fatty Acid Metabolism