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University of Tabuk
Faculty of Applied Medical Science
Department of Medical Laboratory Technology
Hematology 1 MLT 205 , AY 1433-1434, Second Semester
Date :
Homework 1
Student Name : ……………………………………………………………………. Student Number: ……………………………………………….
1. List the organs or systems involved in adult hematopoiesis.
2. Describe a "pluripotent cell".
3. Define the following terms:
a. erythropoiesis
b. granulopoiesis
c. lymphopoiesis
d. megakaryopoiesis
4. Differentiate between a monocyte and a macrophage.
5. The hematopoietic stem cell is capable of :
a-Replication
b-Differentiation
c-Replication and differentiation
6. The process of hematpoiesis under the control of:
a- Growth hormone
b- Hematopoietic growth factorsc
c- Thyroid hormone
Homework-2
1. What should you do to avoid having anemia?
2. Why is oxygen important to blood and to the cells?
3. Mature erythrocytes:
A) have a centrally located nucleus.
B) are actually just cellular fragments.
University of Tabuk
Faculty of Applied Medical Science
Department of Medical Laboratory Technology
C) contain hemoglobin in their cytoplasm.
D) mature from cells called megakaryocytes.
E ) do not contain protein
4. Plasma is:
a) blood that has no red blood cells
b) the liquid portion of blood including clotting factors
c) the liquid portion of blood after it has clotted
d) the proteins of blood
Homework-3
1. A 35 year old pregnant woman is seen for easy fatigue for many months. Physical
examination is positive for pale conjunctiva, mild spooning of nails. Her Hb is 7.1
gm/dl.
A. What is the most likely diagnosis for this case?
B. What would you expect her PCV to be?
2. Which of the following normally contains >10% of body iron?
*
Transferrin
*
Heart
*
Neutrophils
*
Macrophages
3. All can cause Iron deficiency anemia EXCEPT:
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Menorrhagia
*
bleeding from GIT
*
Pregnancy.
*
Transcoblamin 1 deficiency
4. With an iron deficiency anaemia:
*
Both serum iron and total iron binding capacity are reduced
University of Tabuk
Faculty of Applied Medical Science
Department of Medical Laboratory Technology
*
The blood film shows a hyperchromic microcytic picture
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The reticulocyte count is low in relation to the degree of anaemia
*
Serum ferritin levels are increased
*
The platelet count may be increased
Homework-4
1. What is the difference between Megaloblastic and pernicious anemia?
2. Which ONE of the following is NOT TRUE about megaloblastic anaemia?
I.
It is always caused by B12 or folate deficiency
II.
Bone marrow appearances are identical in B12 or folate deficiency
III.
It is caused by defective DNA synthesis
IV.
It may be caused by nitrous oxide
V.
It is associated with jaundice
™ A 32 year old male is admitted to the emergency department suffering from
multiple gunshot wounds to the abdomen. Surgery results in removal of the
all of the jejunum. Several months later, the patient complains of being tired.
A CBC indicates an increased MCV of 125, decreased Hb and Hct. Which of
the following is consistent with these data? Why?
a)iron deficiency anemia
b)anemia of chronic disease
c)Vit B12deficiency
d)Folate deficiency
e)Sideroblastic anemia