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VETERINARY – A Instructor’s Guide Part I – Disease -- Fundamentals Purpose 1. 2. 3. 4. Know the three primary routes of entry of disease Know the difference between a contagious and an infectious disease Know the difference between a viral and a bacterial disease Know the disease processes including shock, fever, dehydration, inflammation, edema and arthritis Teaching Suggestions 1. “contagious” vs. “infectious” means two entirely different things depending on which reference you are using (MH vs. KYH). These references are separated out to show the differences. Reading other materials suggests that the definition given in KYH is more common. Alert students to this problem so they do not become too confused/frustrated 2. Be sure students understand the two sides of inflammation (good/bad) so they recognize the need for it to happen in a controlled manner. Routes of disease entry 1. mouth Routes of entry swallowed VN 397 2. nostrils skin inhaled 3. skin wounds insects directly (e.g., burrowing worm) 4. urinogenital tract 5. conjunctiva of eyelids 1. can provide clues to what the horse is suffering from Why is this useful Example: if the horse has recently had a wound and then becomes ill, disease that enter via a wound may be considered as culprits first 2. can help determine what measures are taken to prevent spread to non-infected animals 3. route of entry can be used to classify various disease causing agents (e.g., bacteria) VN 400 Contagious vs. infectious Contagious MH 345 Description KYH (74) readily spread (KYH 74) find easy path from one animal to another path on things like hands, clothing, buckets, food sacks, muck sacks etc. viruses tend to be very contagious but not always highly infectious MH require direct contact between horses or contaminated people or equipment can be passed between horses or between horses and people Examples KYH (74) strangles contagious equine metritis (CEM) ringworm MH ringworm lice Veterinary (A) – Instructor’s Guide -- 1 Infectious MH 345 Description KYH (74) the organism will inevitably set up infection when it enters Examples KYH (74) tetanus anthrax MH direct contact is not required as micro-organism can be carried in other ways MH strangles influenza EVR EVA Bacterial vs. viral Virus KYH 75 Bacteria KYH 72 Description 1. smaller than bacteria easily carried through the air from one animal to another 2. require living cells to live and reproduce they do not survive for long in nature 3. can grow rapidly 4. can mutate into new varieties 5. tend to be very contagious but not always highly infectious “viral” refers to a disease causes by a virus 1. single-cell organisms which reproduce by simple division 2. can live freely in water, dirt and other environments can stay alive outside the horse poor sanitation increases risk of bacterial infection (VN 398) 3. widely distributed in nature soil skin genital tract of female (VN 398) digestive tract 4. some are very useful those involved in digestion 5. often not a primary cause of disease but are able to set up infection if come in contact with tissues that are already damaged secondary infection such as pneumonia 6. two types aerobic anaerobic 7. vary greatly in ability to set up disease 8. many can be reduced/eliminated through use of antibiotics some become resistant to antibiotics especially if antibiotics used indiscriminately Examples Influenza EVR EIA sleeping sickness EVA rabies strangles CEM tetanus botulism “bacterial” refers to a disease caused by a bacteria Veterinary (A) – Instructor’s Guide -- 2 Other terminology Infection Communicable Virulence/ pathogenicity VN 397 aerobic anaerobic Disease processes What is a “disease process” USAB 353 Why know what they are? USAB 353 What are the six disease processes? USAB 354 Shock Notes USAB 354 Signs USAB 354 Causes USAB 354 Treatment USAB 354 an invasion of tissues (KYH 72) a disease which can be passed from one horse to another does not differentiate between how they are passed the more “virulent” the organism the greater its ability to set up disease and cause symptoms having oxygen lacking oxygen e.g., anaerobic environment is one where oxygen is not present certain processes that frequently occur in response to illness, injury or other conditions 1. there presence may indicate things about the underlying condition disease processes occur for specific reasons 2. some disease processes can cause permanent damage to tissues recognizing them allows horse owner to treat them or to call the veterinarian 1. shock 2. fever 3. dehydration 4. inflammation 5. edema 6. arthritis 1. the bodies response to trauma 2. acute and progressive failure of the peripheral circulation (blood circulation to outer body parts such as the legs and head) body tried to conserve its resources to deal with serious injury 1. 2. 3. 4. 5. 6. 1. 2. 3. 4. 5. 6. 7. 8. 1. 2. 3. 4. 5. can progress until blood pressure falls dangerously low and death follows trembling, sweating, cool skin depression, apathetic attitude cold extremities (ears and legs), subnormal temperature rapid, weak pulse; low or falling blood pressure pale or bluish mucous membranes weakness, collapse massive bleeding sever trauma burns major infections intestinal obstructions dehyrdration heart failure anaphylactic shock (sever allergy reaction) keep horse quiet keep horse warm (not so warm as to raise temperature worsen shock) control bleeding avoid dehydration call veterinarian likely provide intravenous replacement of fluids to restore blood volume and blood pressure Veterinary (A) – Instructor’s Guide -- 3 should be treated promptly by veterinarian no matter what the underlying cause, call the vet before shock progresses to a dangerous point never administer tranquilizers to a horse in shock as this can lower blood pressure further Fever Notes USAB 354 Causes USAB 354 Symptoms 1. 2. 1. USAB 354 Treatment 2. 3. 4. 5. 1. USAB 354 Dehydration Notes USAB 355 Causes 1. USAB 355 2. Symptoms 3. 4. 5. 1. USAB 355 2. 3. 4. 5. 6. abnormal rise in body temperature not caused by exercise, diet or environment can lead to weakness, dehydration and tissue damage sometimes very high fevers (7 to 10 degrees above normal) can be life threatening byproduct of process by which a horse fights infectious diseases or toxins result of toxins that accompany an infection or tissue destruction raised temperature one or more degrees above the horse’s normal temperature (from 99.0 to 100.5 degrees Fahrenheit) chills shivering increased pulse rate sweating call vet to determine the cause and to treat horse antibacterial drugs may be used to control infection special drugs to lower fever body’s water level becomes deficient sufficient water is essential for vital functions a) circulation b) digestion c) cooling d) maintaining chemical balance in cells of the body loses too much water heavy sweating a) obvious b) continuous that dries rapidly less noticeable (e.g., travel in hot weather) diarrhea or urinary conditions (KYH 116) fails to take in enough water winter when sources freeze horse doesn’t want the water (too cold or unfamiliar) result of virus or bacterial infections (KYH 116) conditions of acute pain such as colic (KYH 117) in shock (after accidents or surgery) (KYH 117) “tenting” in pinch test pinch a fold of skin on horse’s shoulder should snap back immediately when released if skin fold remains tented or subsides over a second or two horse is dehydrated hard dry manure slow digestion impaction colic lethargy (KYH 117) Veterinary (A) – Instructor’s Guide -- 4 Treatment USAB 355 Inflammation Notes USAB 355 Process USAB 355 Purpose USAB 356 Causes USAB 355 Symptoms USAB 356 Problems with excessive inflammation USAB 356 Causes of excessive inflammation USAB 356 Treating USAB 356 1. 2. 3. 4. encourage horse to drink a little at a time not a large amount of cold water (especially if horse is hot) administration of IV fluids if severe natural defensive response to injury or infection natural inflammation is good excessive inflammation should be avoided 1. body responds by increasing circulation at the site deliver defense cells (leukocytes and antibodies) a) destroy, dilute or wall of the irritating agents carry away cellular debris a) the results of dead or damaged cells and foreign material 2. exudates gets into surrounding tissues fluid, cells and cellular debris that escapes (exudes) out of capillaries into surrounding tissues contains (depending on location and type of inflammatory reaction) a) blood b) serum c) pus d) fibrin or mucous 3. eventually leads to healing and repair of the damaged tissues 1. essential part of healing process heal the wound defeat the infection repair damaged tissue 1. injuries 2. wounds 3. burns 4. disease causing organisms (pathogens) the toxins they produce 5. poisons 6. venoms 7. antigens substances against which the animal possesses antibodies 1. heat from increased blood supply to area 2. pain from swelling and nerve irritation 3. redness not always visible 4. loss of function of inflamed area from pain and swelling 1. damage to the body 2. proud flesh 3. excessive scar tissue 4. loss of function 1. irritation from strong antiseptics 2. irritation from flies 3. excessive movement 1. application of cold and immobilizing the part (early treatment for sprains, strains and bruises) reduce the initial inflammatory response 2. provide antibiotics if natural defences are inadequate to defeat an infection Veterinary (A) – Instructor’s Guide -- 5 under the consultation of a veterinarian 3. drugs (corticosteroids and non-steroidal anti-inflammatory drugs like phenylbutazone) can reduce inflammation use under advice of veterinarian Edema Notes USAB 356 Causes swelling or the accumulation of excess fluid in the tissues 1. lack of exercise stocking up a) edema in the hind legs or all four legs 2. certain illnesses 3. parasite infestation 4. inactivity 5. heart or kidney disorders that interfere with normal circulation of blood and lymph 6. related to low pressure in the veins 7. related to abnormal protein or salt content in the blood 1. swelling is cool and painless if pressed with a finger a “pit” or imprint remains USAB 356 Symptoms USAB 356 Treatments USAB 356 Arthritis Notes Symptoms Types Traumatic 1. 2. 3. along midline of abdomen and in the sheath or in legs is “stocked up” look for and treat underlying cause turnout paddock improve exercise stable bandages inflammation of a joint may range from mild to severe Two types 1. may be acute (a recent sprain) 2. chronic (long term condition) 1. heat and swelling in the joint 2. pain on movement There are several types caused by trauma to the joint (sprain or blow) usually acute USAB 357 Septic Treatment 1. cool the injury (cold hosing, cold water bandages or cold gel or ice packs for 20 minutes at a time) 2. apply pressure bandage (to limit movement and swelling 3. rest joint is invaded by infectious organisms through a wound or puncture or a systemic infection USAB 357 Symptoms 1. extremely painful 2. joint swells badly Treatment requires prompt veterinary treatment infection can destroy the joint Veterinary (A) – Instructor’s Guide -- 6 Degenerative USAB 357 chronic condition develops from trauma and long-term wear and tear leading to inflammation over a long period of time usually in older horses trauma and abuse of steroids may cause it in young horses degree of lameness depends on the joints affected and the severity Process 1. surface of the cartilage lining the joint slowly erodes 2. synovial fluid changes consistency joint surface is less smooth and not as well lubricated 3. coral-like calcium depostis may form or small pieces of bone may chip off 4. joint becomes tender and painful 5. loses its range of motion 6. may become fused or immovable Treatment 1. if mild horse may improve as warms up 2. anti-inflammatory drugs (aspirin and phenylbutazone) may give some relief 3. careful warming up 4. right shoeing 5. therapies such as massage or whirlpool therapy may help 6. usually do best worked lightly but regularly 7. should not be overstressed Part II –Disease -- Specifics Purpose 1. Know the cause, symptoms, treatments and system affected for various diseases including botulism, strangles, roaring, rhinopneumonitis, CEM, EIA, rabies, Equine Encephalomyletis and EVA Teaching Suggestions 1. Students will have reviewed most of these in the past be sure they know the differences between them 2. They should know both the full names and the acronyms 3. Any examples of these diseases (people they know etc.) will help them remember. Botulism USAB 358 Notes System affected Cause Symptoms Prevention causes “shaker foal syndrome) Nervous 1. toxin produced by Clostridium bacterium found in hay (especially large round bales) when animal carcasses are baled in 1. paralysis of tongue and jaw 2. drooling 3. inability to swallow 4. weakness 5. shuffling gait 6. paralysis 7. death due to respiratory failure begin 3-7 days after ingestion vaccination Veterinary (A) – Instructor’s Guide -- 7 Treatment mild cases may survive if treated promptly Equine Infectious Anemia (EIA/Swamp fever) USAB 359 Notes transmitted by bloodsucking flies, mosquitos, contaminated needles from mare to foal in milk (VN 430) name “swamp fever” comes from frequency around swamps/mosquitos various forms (see symptoms) Circulatory/lymphatic System affected Cause virus carried in blood Symptoms Acute form 1. fever 2. edema of legs and midline 3. depression 4. loss of appetite 5. weight loss 6. often fatal 7. jaundice and soft swelling of the abdomen, prepuce (in colts and geldings) and legs (VN 430) 8. small (pin head size) haemorrhages on lining of tongue and on mucous membrane of nose (VN 430) Subacute form 1. similar to acute but less severe 2. death seldom occurs Chronic form 1. unthrify appearance 2. loack of stamina 3. periodic flare-ups of acute or subacture form Prevention Treatments Inapparent carrier 1. no apparent symptoms 2. horse test positive for EIA antibodies 1. no vaccine available 2. require a negative Coggins test for pre-purchase exam entry to stables shows and rallies interstate shipping 3. isolate horses testing positive for EIA from healthy horses 4. attempt to control fly populations (VN 430) supportive therapy such as iron treatments or blood transfusions (VN 430) Equine Encephalomyletis (sleeping sickness, EEE, WEE, VEE) USAB 359 Notes transmitted from infected birds to horse or human by mosquito bite survivors often have permanent brain damage various strains a) Eastern (EEE) b) Western (WEE) c) Venezuelan (VEE) Brain/nervous system System affected Virus carried in blood Cause 1. high fever (up to 106o F) Symptoms 2. loss of appetite (VN 431) Veterinary (A) – Instructor’s Guide -- 8 Prevention Treatments 3. depression (VN 431) 4. drowsiness 5. hypersensitivity to sound and touch (VN 431) periods of excitement and restlessness with apparent blindness 6. circling 7. pressing head against walls 8. paralysis tongue may hang out (VN 431) 9. death vaccination before mosquito season isolate infected animals (VN 431) supportive measures to keep individual alive until recovery takes place (VN 431) Equine Viral Arteritis (EVA, pinkeye) USAB 360 Notes transmitted by inhaling droplets and in breeding causes abortions stallions may become “shedders” that show no symptoms but pass virus in semen Respiratory, reproductive System affected Herpes virus Cause 1. fever (102 to 106oF) Symptoms 2. nasal discharge 3. increased respiratory rate 4. edema of limbs 1. vaccination Prevention 2. testing 3. restricting use of affected stallions 4. restricting importation of affected stallions Rabies USAB 362 Notes System affected Cause Symptoms Prevention Treatments transmitted by bite of rabid animal including skunk, foxes, raccoons, bats, dogs and cats all warm blooded animals including man are susceptible incubation period may be up to several months after bite of rabid animal Brain/nervous system Rhabidovirus 1. facial paralysis 2. lameness 3. colic 4. faulty vision 5. personality change 6. fatal (always 1. vaccination of horses, pets barn cats no cure Strangles (distemper) USAB 362 Notes highly infectious transmitted in mucus, contaminated feed/water horses are infective for 4 to 6 weeks organism can live in environment for a month of longer horses are immune after and infection (KYH 76) occasionally organism spreads down lymphatic chain producing internal abscesses in thorax or abdomen “bastard strangles” (VN 411) Veterinary (A) – Instructor’s Guide -- 9 System affected Cause Symptoms Prevention Treatments Roaring USAB 362 Notes System affected Cause Symptoms Things it can be confused with KYH 108 Respiratory, lymphatic Bacterium (streptococcus equi) 1. lack of appetite may be due to sore throat and inability to swallow (KYH 76) 2. fever (103 to 105oF) 3. nasal discharge become purulent 4. upper respiratory tract is inflamed can restrict breathing “strangles” (VN 411) 5. lymph nodes affected swell abcess break open drain pus (may continue for weeks KYH 76) 1. vaccination 2. take isolation/quarantine precautions with new or suspect horses strict hygiene (VN 414) 1. antibiotics given before abcesses form especially if bastard strangles suspected (VN 414) 2. good nursing care keep warm (KYH 78) out of draughts (KYH 78) soft food/mashes (KYH 78) clean nostrils (VN 414) hot pads applied to swellings (VN 414) 3. isolate infected horses non-contagious more common in very large horses seems to be a genetic link (KYH 107) in early stages the sound is more of a whistle (KYH 108) a horse may whistle first and then progress to roaring but not the other way around (KYH 108) Respiratory 1. damage to laryngeal nerve (usually the left one (KYH 107)) paralysis of one side of muscles controlling vocal cords one cord hangs in airway creating the abnormal sound 2. sudden, violent exertion when unfit (NZ2 238) 3. may occur following bout of strangles or any other respiratory disease(NZ2 238) 1. roaring sound during inspiration especially during exercise 2. affects stamina in racing or fast work air flow is somewhat restricted (KYH 108) 1. Paralysis of the soft palate 2. Bridle noises a) when horse is ridden or longed with head in flexed position b) dropped noseband inhibiting the nostrils 3. Infections of the pharynx, larynx, nasal passages or lungs 4. Infection of glands and related discharges 5. Presenting horse in fat and unfit condition for a test of wind 6. High blowing noise as air passes over false nostril Veterinary (A) – Instructor’s Guide -- 10 Prevention Treatments 7. Noises as horse exhales strongly advised not to breed horses that suffer from roaring (KYH 108) corrected by surgery Equine Viral Rhinopneumonitis (EVR) USAB 360 Notes transmitted by inhaled droplets, contact with infected horses, contaminated feed or water various forms including respiratory, reproductive and paralytic (KYH 86) Respiratory, reproductive, rarely nervous System affected Herpes viruses: EHV 1, 2 or 3 Cause 1. fever (up to 106oF) Symptoms 2. cough 3. nasal discharge 4. glands of throat may be swollen but not much as for strangles (KYH 86) 5. purple membranes of nasal passageway (KYH 86) 6. secondary bacterial infection may occur 7. abortion or weak foals that die soon after birth 8. paralysis (in the rare form affecting nervous system) 1. vaccination Prevention vaccinate mares in fifth, seventh and ninth months of pregnancy (VN 426) 1. good nursing care Treatments foals particularly susceptible to draughts and cold (KYH 87) 2. isolate from other horses 3. antibiotics in cases with a secondary bacterial infection Contagious Equine Metritis (CEM, Taylorella equigenitalis) VN 420 Notes highly infections disease veneral (sexually transmitted) “metritis” means uterine infection only in mares (KYH 81) carried on the external genitalia of stallions transmitted at mating to mares most mares are highly susceptible some (especially older mares) take long periods to recover and may require treatment some become carriers (have organism but show no symptoms) colt foals born to infected mares may be carriers until bred and then can start an epidemic Reproductive System affected Bacteria Taylorella equigenitalis Cause 1. genital inflammation Symptoms 2. vaginal discharge 3. lowered fertility 4. exudates on vulval lips and on hairs of the tail, buttocks and inside of hocks 5. may return to heat unexpectedly often with shortened interheat periods 6. usually breed successfully once the infection has been eliminated 7. stallions don’t have clinical signs 8. diagnosis is made on culturing organism from swabs taken from mare’s genital tract or from males genitals Prevention do not return a stallion to breeding until several swabs over a period of time are clean Treatments 1. disease is usually self limiting 2. clears with sexual rest after about three months 3. treat infected mares with antibiotics Veterinary (A) – Instructor’s Guide -- 11 Stallions 1. washing sheath and penis of stallions with disinfectants 2. apply antibiotics cream over a prescribed period Part III – Supplies and Techniques Purpose 1. Know how to administer various medications 2. Know the names and uses of various drugs Teaching Suggestions 1. Important for students to know the difference between an analgesic (pain reliever) and an anti-inflammatory. Can be confusing because reducing inflammation is a means of relieving pain. 2. Students should know the drugs that are common for certain procedures such as dental work. Administering medication 1. Orally (by mouth) Methods of a) On the tongue (e.g, wormer) administering b) In food (powder or syrup) (MH – 348; KYH – c) moisten food a little so it sticks 195; VN - 477) d) sweeten if necessary e) tablets can be in apple or crushed 2. Locally (directly to skin, eye, nostrils etc.) 3. Parenterally (injection by qualified person) a) subcutaneous (under skin), b) intramuscular (into muscle) or c) intravenously (into blood stream) 4. Stomach tube (by vet) (VN – 478) 5. Inhalation: steam vapours (VN – 481) 6. Enema: inserted into rectum (VN – 481) 7. Intravaginal or intrauterine administration: directly into vagina or uterus(VN – 482) Medication Notes Notes USAB 363 Guidelines for using medications safely 1. 2. 3. 4. 5. any medication strong enough to do good can also do harm if misused drugs and prescription medications should be given only on orders from veterinarian dangerous to assume that because a drug was successful in one case it can be given in another veterinarian may prescribe certain drugs or medications for you to administer or leave a supply to be used under certain circumstances always check to find out if the drug you are considering is allowed in the under the rules governing your particular sport/event only keep drugs and medications that your vet agrees you should have only give medications with the advice and approval of your vet when a drug is prescribed write down complete information on how to administer it how often how long symptoms side effects be sure the vet knows of any other drugs or medication the horse has been given recently including dewormers have your vet teach you how to administer medications by mouth and Veterinary (A) – Instructor’s Guide -- 12 intramuscular injections including precautions 6. store drugs in clean place temperature recommended by manufacturer 7. check date stamped on box and throw out any that are past their date 8. keep within the law possession of needles, syringes and certain drugs is regulated by low keep under lock and key if necessary dispose of appropriately Terminology and drug types USAB 364 The following terminology will help clarify the various terms used to describe Note drugs and medications. Examples have been provided where appropriate. 1. helps lower fever anti-pyretic USAB 366 1. relieve pain by blocking sensation of pain but not other sensations analgesic 2. pain is not blocked but is relieved/decreased 3. relieved in two main ways a) action on the central nervous system (e.g., narcotics) b) reducing inflammation that results in pain (e.g., steroidal and nonsteroidal) 1. powerful pain relievers that act on central nervous system narcotic 2. can cause serious side effects must be used only by veterinarian possession is regulated by law 1. pain relievers that control inflammation steroids 2. serious side effects including a) suppress immune responses making horse more vulnerable to infections of all kinds b) suppression of body’s ability to produce natural coricosteroids c) depressed calcium and potassium levels d) weakness e) loss of muscle mass f) laminitis Non-narcotic, non- 1. pain relievers that do not contain steroids or narcotics 2. some may be prescribed by the veterinarian for the horse owner to administer steroidal Analgesics Examples 1. Banamine 2. Dipyrone 3. Torbugesic 1. drugs that reduce inflammation without use of a steroid Non-steroidal 2. some may be prescribed by the veterinarian for the horse owner to administer antiinflammatories an anti-inflammatory may be used to either reduce pain or to prevent an (NSAIDS excessive inflammatory response NSAIDs USAB 366 Notes 1. do not cure the problem, just make horse more comfortable for horse to move helps keep area from “scarring down” and losing range of motion 2. must carefully balance pain control and exercise to prevent overstressing re-injuring Veterinary (A) – Instructor’s Guide -- 13 Use 1. 2. Problems 1. 2. Example 1. 2. 3. Tranquilizers USAB 364 1. Notes 2. 3. 4. 5. 6. 7. Use 1. Results/precautions 2. 3. 4. 1. 2. 3. Examples 4. 1. 2. 3. worsening original injury treat variety of musculo-skeletal problems sprains strains overuse of muscles joint injuries arthritis are anti-pyretics (anti-fever) used to reduce fever resulting from bacterial or viral infection can be abused suppress symptoms for hard work or competition without regard to horse’s long-term soundness hard on the gastrointestinal tract over dosage or prolonged usage can result in ulcers ulcers or soreness in mouth can be early sign that ulcers of gastrointestinal tract may be occurring Phenylbutazone Aspirin Ketoprofen also known as sedatives produce a calming effect work on the brain or central nervous system work best if administered while horse is calm allow undisturbed for 5 to 15 minutes until drug takes effect individual sensitivity to tranquilizers varies’ forbidden substances under some horse show rules and result in severe penalties during veterinary treatment raise horse’s pain threshold but don’t block pain can still feel pain and may react violently to startling or painful stimuls clipping shipping other procedures may become unsteady on his feet fall down more easily than usual pay attention while holding a tranquilized horse consider dosage carefully when shipping/transporting so horse won’t fall during loading, travel and unloading heavily sedated horses may have difficulty swallowing choke may result do not allow to eat or drink until they have returned to normal alertness not recommended to tranquilize for training purposes they block conditioned responses and learned behaviour increase risk of stumbling or falling increase risk of stumbling or falling never ride a tranquilized horse (see other precautions above) Acepromazine Xylazine Dormosedan Veterinary (A) – Instructor’s Guide -- 14 Antibiotics Notes Use Results/precautions Examples 1. 2. 1. 2. 3. 4. 5. drugs that kill bacteria only effective against bacterial infections not viral infections specific antibiotics are only effective against certain types of bacteria may have to grow a culture to see which antibiotic would be most useful only on advice of a veterinarian follow the recommended schedule continue giving it as long as it was prescribed (even if condition seems improved) bacteria can become resistant giving them unnecessarily (e.g., for a viral infection) in too small doses for too short a period to be effective some antibiotics have serious side effects penicillin streptomycin sulfonamides ampicillin tetracycline Veterinary (A) – Instructor’s Guide -- 15 Specific drugs and medications Drug Type Acepromazine Tranquilizer (PromAce, Promazine Granules) USAB 364 Xylazine (Rompun) Tranquilizer USAB 365 Dormosedan Tranquilizer USAB 365 Banamine Non-narcotic, Action 1. depresses central nervous system sedation relaxation reduction of involuntary movements (flinching) 2. does not relieve pain will not prevent a horse from moving or kicking if startled or fels pain 1. sedative that affects the brain 2. some pain relief 3. some muscle relaxing effects 4. slows heartbeat and respiration conditions similar to sleep 1. sedative 2. some analgesic properties 3. sedate horses and control pain during veterinary procedures 1. acts directly on inflamed Administration 1. intramuscularly 2. intravenously 3. granules added to feed 1. oral paste form Cautions 1. drop in blood pressure do not give to horse in a) shock b) dehydrated c) septic (severe infections) d) in poor condition (malnutrition) e) colicky 2. do no use if recently dewormed with phenothiazine or peperazine 3. accidental injection into an artery (especially carotid) can produce signs from excitement and disorientation to seizures and death 1. may appear relaxed and sleepy but can kick or jump suddenly 1. not intended for long Use horse holds head very low a) dental work b) work on head or eyes c) choke 1. relief of colic pain Veterinary (A) – Instructor’s Guide -- 16 Drug (Flunixin Meglumine) Type non-steroidal antiinflammatory Action tissues 2. reduces fever 3. reduces pain USAB 365 Dipyrone USAB 366 Non-narcotic, non-steroidal antiinflammatory 1. analgesic 2. anti-pyretic Administration 2. granules added to feed 3. intramuscularly 4. intravenously 1. intravenously 2. intramuscularly 2. 3. 1. 2. Torbugesic USAB 366 Phenylbutazone (bute, probute) USAB 366 Non-narcotic, non-steroidal antiinflammatory NSAID Cautions term use must not be given for more than five days high oral doses over a prolonged period may produce gastrointestinal ulcers do not give with phenylbutazone, chlorpromazine or barbiturates overdose can cause seizures (especially in old or debilitated horses or those with heart disease 1. used to control fevers (e.g., in viral illnesses) 2. relieve colic pain 1. non-narcotic analgesic 1. acts directly on inflamed tissues 2. control pain 3. control fever associated with bacterial or viral infections 4. not effective against colic pain 5. sometimes used to treat navicular Use 2. muscle bone and joint diseases 1. 2. 3. 4. oral gel or paste tablets powder intravenously 1. very irritating to tissues 2. can cause severe tissue damage if injected outside a vein or repeated injections are made into same vein 3. overdoses can cause mouth and tongue lesions, gastrointestinal ulcers and kidney damage 4. do not use in conjunction with blood thinners (e.g., warfarin or Coumadin) effective for relief of colic pain 1. relief of musculoskeletal disorders a) strains b) sprains c) muscle overuse d) tendonitis e) acute joint injuries f) arthritic conditions 2. pain from a) injuries b) infections c) laminitis d) other Veterinary (A) – Instructor’s Guide -- 17 Drug Type Action Aspirin USAB 367 NSAID 1. fever-reducing 2. anti-inflammatory 3. more often used for reducing fever than for controlling pain Ketoprofen (Ketofen) NSAID 1. similar to human ibuprofen 2. control inflammation Administration 1. orally in tablets or powder Cautions 1. irritating to stomach lining 2. should not be used over long periods of time USAB 367 Dexamethazone (azium) and other corticosteroids USAB 367 Corticosteroid 1. 2. 3. 4. orally muscularly intravenously directly into a joint Use painful conditions reduces fever from bacterial infections but ineffective against fever from other things like heat stroke relieve pain in muscul-skeletal disorders including a) strains b) sprains c) muscular overuse d) tendonitis e) joint injuries f) arthritis 1. can reduce pain, heat and swelling and make injury appear better very quickly but it is not healed and is extremely vulnerable to further damage 2. suppress immune response Veterinary (A) – Instructor’s Guide -- 18 Part IV – Parasite Control Purpose 1. Know the principles of parasite control in the horse/herd 2. Know the names of recent drugs for parasite control and discuss their use and rotation 3. Know the term “fecal count” and how it relates to parasite management Teaching Suggestions 1. Note: moxidectrin is the active ingredient of Quest (a recent deworming product) It is not included in any of the current required reading materials (perhaps because it is so recent). I have included a row in italics at the bottom with the basic information for student information. Please note it is from Quest labelling not a required reading source. Notes Components of a good control system 1. 2. 3. 4. the greater the number the horses in the smaller the area the greater the exposure to parasites “anthelminics” is another term for dewormer regular deworming rotation of dewormers testing measures to prevent infestation 1. 2. 3. 4. 5. 6. local conditions climate time of year ages of horses number of horses needs of individual horses USAB 345 Considerations for a good control system USAB 345 veterinarian’s advice is invaluable Deworming Schedule USAB 345 Choosing a product USAB 345 1. 2. 3. 4. Administering dewormers 5. 6. 7. 1. USAB 348 2. usually every 6 to 8 weeks some products are intended to be fed in small doses every day (e.g., Strongid C) dose all horses sharing a pasture at the same time (MH 357) safe age type of horse a) mature b) young stock c) pregnant or lactating mares d) aged horses administered in correct dosage must know the weight of your horse effective against present parasites effective against present stage of life cycle if horse lives with donkeys it will require a lung worm dewormer (MH 357) Oral Paste most common rinse horse’s mouth clean first as he can spit it out if he has a mouthful of hay Stomach Tube you are sure horse got entire dosage some wormers can only be given by stomach tube (too caustic to be given Veterinary (A) – Instructor’s Guide -- 19 orally) must be done by a veterinarian some horses are difficult to tube 3. Powder or Granules in Feed least reliable method a) horse may refuse to eat dewormer b) may only eat part of a dose Rotation of wormers Notes USAB 348 a single deworming product will kill most but not all of the targeted internal parasite if the same drug is used to target that parasite repeatedly, those parasites that survive may develop a resistance to it dewormers should be rotated periodically dewormers must be rotated based on active ingredient and classification of drug not just brand seek the advice of a veterinarian rotate annually (MH 357) o changing more frequently can result in resistance problems (MH 357) Testing for Parasites Fecal parasite a microscopic examination of a fecal sample count shows the number and types of parasites present in the horse only show how many mature, egg laying parasites are present USAB 349 does not indicate levels of migrating larvae (much more damaging) 1. routine annual count done in late June or early July Scheduling adult parasite population is greatest USAB 349 check effectiveness of parasite control program 2. new horses should be tested especially if they show signs of infestation Reducing Exposure to Internal Parasites Notes nearly impossible to completely eliminate exposure to parasites USAB 349 can keep the exposure to low levels 1. good hygiene Basic Principles USAB 349 2. preventing contamination of pastures and feed by parasite eggs and larvae 3. measures that break parasites’ life cycles 4. reduce parasite numbers 1. fecal tests performed on all new horses Recommendations 2. deworm new horses 48 hours before being turned out in pastures of paddocks USAB 349 3. avoid overcrowding and overgrazing pastures the more horses/manure per acre the greater the parasite load 4. keep feed, hay and water from contamination withmanure avoid feeding on ground use feeders 5. pick up manure from paddocks at least twice a week do not spread manure directly from stables onto pastures a) composting will kill some eggs and larvae large strongyle larvae survive for several weeks small strongyle larvae survive up to eight months ideally hose manure is not spread onto horse pasture at all 6. if possible, rest or rotate pastures periodically Veterinary (A) – Instructor’s Guide -- 20 Deworming Products Drug Brand Name Dichlorvos Cutter Dichlorvos Horse Wormer Febentel Fenbendazole Rintal Combotel Negabot-Plus Panacure Telmin, Telmin B Ivermectin Equalvan Equimectrin Zimectrin Piperazine Piperazine 17% or 34% Peperazing water wormer Pipfuge Pip-Pop 320 Benzelmin Benzelmin plus Oxfendazole Oxibendazole Anthelcide Eq Equipar R Form Pellets Effective Against Ascarids Bots Large and small strongyles Paste Liquid Ascarids Pinworms Large and small strongyles Ascarids Pinworms Roundworms Large and small strongyles Tapeworms Threadworms Ascarids Pinworms Large and small strongyles Ascarids Bots Onconchera Pinworms Large and small strongyles Threadworms Ascarids Pinworms Large and small strongyles Granules Paste Liquid Paste Powder Suspension Paste Liquid In water On feed Paste Powder Liquid Paste Suspension Comments not for foals may cause diarrhea do not withhold feed avoid muscle relaxants, general anesthetics and insecticide for 2 weeks after use effective against large strongyle larvae when given in double dose for 5 days double dose required for tapeworms and roundworms Effective against all internal parasites including larvae, except tapeworms Treated horses may show colic symptoms or muscle tremors (especially in case of overdose) Ascarids Pinworms Large and small strongyles Ascarids Pinworms Large and small strongyles Veterinary (A) – Instructor’s Guide -- 21 Drug Brand Name Form Pyrantel Pamoate Imathal Strongid Paste Suspension On feed Pyrantel Tartrate Banminth Purina Horse and Colt Wormer Strongid C Feed additive Suspension Effective Against Threadworms Ascarids Pinworms Large and small strongyles Tape worms (Strongid T label) Ascarids Pinworms Large and small strongyles Threadworms Comments Daily feed additive Thiabendazole Equizole Equizole A Trichlorfon Combot Liquid Combot Paste Negabot Paste Telmin B Benexelmin Plus Combotel Dyrex Liquid Paste Moxidectrin Quest Quest gel Gel Paste Information from Quest label not a required reading source Ascarids Pinworms Large and small strongyles Ascarids Bots Pinworms Large and small strongyles Encysted cyathostomes Ascarids Pin worms Hair worms Large mouth stomach worms Bots May cause diarrhea and mild colic symptoms Do not withhold feed Avoid stress, surgery, muscle relaxants and insecticide use for 2 weeks after use. Extreme caution should be used when administering the product to foals, young and miniature horses, as overdosage may result in serious adverse reactions. Do not use in horses or ponies intended for food. For animals 4 months of age or older Transient depression, ataxia and recumbency may be seen when very young or debilitated animals are treated. Reproductive safety studies demonstrate a wide margin of safety when the product is used in the treatment of estrual and pregnant mares and breeding stallions Veterinary (A) – Instructor’s Guide -- 22 Part V – Systems Purpose 1. Know the primary parts, functions and diseases of the respiratory, circulatory, lymphatic,, nervous and urinary systems 2. Know the functions/purpose of the skin Teaching Suggestions 1. Note the possible typo in USAB 233 including EVA as a disease of the circulatory/lymphatic system. Circulatory System Function Blood Components (3) Types of blood USAB 230 Vessels USAB 230 Arteries Veins 1. transportation a) oxygen from lungs to cells b) carbon dioxide from cells to lungs c) nutrients and water from digestive tract to all cells d) waste from cells to kidneys e) hormones and defense cells throughout the body in blood 2. bathe cells in fluid 3. maintain heat of the body closely associated with the lymphatic system 1. Plasma fluid part contains serum and cells that aid in clotting 2. Red Blood cells contain hemoglobin carry oxygen and carbon dioxide produced in bone marrow 3. White blood cells defense cells act against harmful germs in case of disease or injury 1. Deoxygenated dark red depleted of oxygen carries carbon dioxide from cells heart lungs 2. Oxygenated bright red corries oxygen from lungs through heart body tubes that carry blood around the body vary in size grouped according to the direction they carry blood and their size movement into and out of the bloodstream happens through cell membrane transport systems carry blood away from heart aorta is largest (carries blood out of heart) arteries branch into arterioles branch into capillaries when an artery is cut the blood spurts as the blood is under pressure from the heart lose a lot of blood in a hurry increased risk of shock (USAB 232) carry blood back to heart capillaries group together into venules group together into larger veins flow into vena cava (the larges vein) vena cava carries blood back to the heart when a vein is cut the blood comes in a continuous flow from the wound Veterinary (A) – Instructor’s Guide -- 23 Capillaries The Heart USAB 229 Chambers USAB 230 Flow Conditioning the heart USAB 232 Diagram of blood flow 1. 2. 3. 4. 1. 2. 3. 4. 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. (USAB 232) tiny blood vessels between arteries and veins their walls are only one cell thick oxygen and nutrients move from blood into cells waste products move into the bloodstream movement into and out of hollow, muscular pump made of cardiac (heart) muscle protective cover called pericardium pumps blood by contracting (squeezing) blood from one chamber to another and out through arteries right atrium (upper chamber) right ventricle (lower chamber) left atrium (upper chamber) left ventricle (lower chamber) deoxygenated blood comes through vena cava from the body it enters the right atrium pumped to right ventricle (through a one way valve) pumped through the pulmonary artery arrives at lungs carbon dioxide is exchanged for oxygen oxygenated blood comes through pulmonary vein enters left atrium (through one a one way valve) pumped to left ventricle pumped through aorta goes out to all parts of the body heart is a muscle and must be kept toned to work efficiently brought into condition gradually (as in interval training) fit heart beats more powerfully more slowly gets more rest between beats Veterinary (A) – Instructor’s Guide -- 24 Diagram of major blood vessels Diseases of the lymphatic and circulatory system 1. 2. 3. 4. equine infectious anemia (EIA) passive edema of legs (stocking up) Lymphangitis Strangles (VN 68) Lymphatic System USAB 231 1. closely associated with the circulatory system Notes series of small vessels throughout the body but does not have a pump (like the heart) moving the fluid movement of the surrounding limbs and muscles moves the fluid (VN 66) main channels of the lymph system discharge into the bloodstream close to the heart (VN 66) 2. valves ensure the fluid only moves in the desired direction (VN 66) 3. drain off excess fluid from all parts of the body prevent tissues from becoming waterlogged (VN 66) 4. play role in defence mechanisms of the body (VN 67) a) the lymph has some white blood cells (VN 67) b) the lymph nodes act a filters (VN 67) c) the lymph nodes play part in antibody production (VN 67) 1. prevent an accumulation of fluid Function MH 431 especially in lower parts of leg where pressure of fluids in the blood vessels is greatest because of gravity surplus fluid absorbed from blood into lymphatics and carried away and deposited back into bloodstream near the heart 2. help fight infection and to repair injuries lymph nodes react to infection by producing lymphocytes and antibodies filter off toxic substances and bacteria at the infection site 3. transport and supply the cells with nutrients fat content important because the capillaries of circulatory system too small to allow fat to be transported 4. remove waste dead or damaged tissue Lymph clear fluid containing white blood cells bathes all cells of the body Lymph vessels thin-walled vessels that transport lymph throughout the body 1. act as filters Lymph nodes 2. produce lymphocytes and antibodies to cope with infection bean shaped masses of lymphatic tissue Veterinary (A) – Instructor’s Guide -- 25 may become enlarged while fighting off an infection (MH 431) Diagram Respiratory System USAB 233 1. take in oxygen Function 2. deliver oxygen to the blood 3. removes carbon dioxide from the blood 4. help control body temperatures by breathing in cold air and out warmer air (MH 431) 5. expel excess water as horse breathes (MH 431) 6. enable horse to smell (MH 431) 7. provide means of communication (MH 431) 1. diaphragm contracts and flattens Breathing 2. ribs expand making chest cavity longer 3. pulls air in through the nostrils and down into the lungs 4. as diaphragm relaxes it expands and the rib cage contract 5. presses against the lungs and expels the air 6. muscles of rib cage, trunk and abdomen also help in this process Notes Diseases 1. at the gallop the abdominal muscles work strongly to bring the hind legs forward under the body at each stride 2. this pushes the abdominal contents (the intestines) forward against the diaphragm and lungs 3. causes horse to exhale in rhythm with each stride respiratory tract naturally contains mucus that is thin and clear (USAB 235) various respiratory diseases can change the quantity and quality of the mucus nasal discharge mucus or matter coming from one or both nostrils a) clear discharge is normal especially when first begins work on a chilly morning b) thick, white or reddish or yellowish discharge points to some kind of infection c) from one nostril usually a sinus infection, a foreign body or a bad tooth on that side d) both nostrils generalized respiratory infection cough forceful expulsion of air to clear the respiratory tract of some foreign material (including excess mucus) Influenza Rhinopneumonitis Strangles Heaves Roaring Veterinary (A) – Instructor’s Guide -- 26 Diagram Interaction between respiratory and circulatory systems diagram Alveoli diagram Upper Respiratory Tract USAB 233 Nostrils horses can only breathe through nostrils (not mouth) hairs inside nostrils help to trap dust and foreign matter Nasal Cavities air passages lined with mucus membrane separated from the mouth by the hard palate and (farther back) the soft palate Nasal Turbinates very thin curling bones inside the nasal passages covered with mucus membrane a) helps trap dust (MH 431) large surface area helps to warm incoming air before it reaches the lungs Sinuses air-filled cavities in the bones of the skull connecting to the nasal cavities reduce weight of the skull and help to warm air as it passes inward Pharynx (throat) a common passage for food and air leads to the larynx Larynx (voice box) box of cartilage (hollow and rigid (KYH 107) located between the branches of the lower jaw contains vocal cords produce sound controls air as it goes in and out prevent food, water and foreign objects from entering the lungs controlled by long nerves (KYH 107) Epiglottis flap that covers the glottis (opening into the windpipe) when the horse swallows Veterinary (A) – Instructor’s Guide -- 27 Trachea(windpipe) long tube made of rings of cartilage which runs from the larynx to the lungs Lower Respiratory Tract USAB 234 Lungs two large elastic organs which fill the chest cavity Bronchi windpipe divides into two tubes or “bronchi” one branch going to each lung inside the they divide into many smaller passageways called bronchioles Alveoli small air sacs only one cell in thickness like bunches of grapes at the end of the bronchioles carbon dioxide and oxygen are exchanged through the wall of the alveoli into the many blood vessels of the lungs “gaseous exchange (MH 431) Pleura protective covering of the lungs Diaphragm large sheet of muscle that runs from the underside of the backbone to the ribs it is the primary breathing muscle the muscles of the ribs and abdomen help Urinary System USAB 240 1. filters out materials from the blood Function waste materials excess water 2. excretes it as urine 3. return necessary proteins, minerals and electrolytes to the system 4. act as buffer in maintaining proper pH of the blood Kidneys normally two but animal can survive on one each kidney contains millions of nephrons (tiny tubules and capillaries) in which filtration takes place blood is circulated through kidneys through the renal veins and renal arteries which are connected to the aorta and vena cava Ureters tubes that carry waste (in form of urine) from each kidney to the urinary bladder Urinary bladder muscular sac that stores the urine until it is excreted Urethra tube that takes urine from the urinary bladder to the outside in male horse it goes through the penis in the female horse the external opening is within the vulva Notes kidneys only filter blood they do not pick up waste from large intestine kidneys can really compensate for each other kidney disease is very rare in the horse Diagram Diseases in the male horse, a bean of smegma can form in the blind pouch of the sheath and block the opening of the urethra Veterinary (A) – Instructor’s Guide -- 28 remove it while cleaning the sheath Nervous System (USAB 242) 1. command and control Function a) receives impulses b) sorts impulses c) transmits impulses 1. brain Central Nervous 2. spinal cord System Peripheral Nerves nerves which run to the muscles and all parts of the body Autonomic Nervous System Nerve cells and their function 1. Sensory nerves a) receive stimuli (a stimulus is a change in the environment such as heat, cold, touch, sound, smell, taste, etc) b) transmit stimuli to brain 2. Motor nerves a) transmit instructions to the muscles 1. controls function of internal organs of the body without the need for conscious awareness (e.g….) a) heart to beat b) lungs to breathe c) digestion to take place Sympathetic and parasympathetic systems operate reflexes and automatic reactions such as shivering from cold. 1. neuron basic nerve cell body of cell has a) branches called dendrites b) long fibers called axons 2. synapse junction between one nerve and another one neuron’s axon touches another’s dendrite Notes 3. works like a relay system information is passed from muscle neuron to neuron neuron –etc. through chemical reactions a) some chemicals stimulate muscles to contract acetylcholine chemical that stimulates muscles b) some chemicals inhibit or stop contraction (or muscle would be in continuous spasm) acetylcholinesterase prevents continuous action of acetylcholine 1. many pesticides (certain fly sprays, some dewormers and flea and tick dips used on dogs) are cholinesterase inhibitors 2. these are cumulative build up in the system 3. if animals receives too much cholinesterase inhibitor (possibly by exposure to several different sources) it can block the release of cholinesterase in the nervous system muscle spasms or seizures due to continuous flow of acetylcholine 4. read ingredients and product warning labels 5. follow directions carefully Veterinary (A) – Instructor’s Guide -- 29 Diagram Diseases The Skin USAB 249 Notes Tetanus Equine encephalomyletis Rabies Botulism Function 1. 2. 3. 4. 5. 6. Layers 7. 8. 1. 2. the largest organ of the body condition of skin and hair coat is an indicator of the horse’s general health healthy skin supple and pliable and hair shines with normal amount of skin oil good grooming, nutrition and general good health are necessary for healthy skin absorbs sunlight synthesizes vitamin D excretion salts, water and waste products through sweat protects body from a) trauma b) excessive radiation c) entry of microorganisms aids in thermoregulation excess heat is radiated into the air outside air temperature and/or moisture in contact with the skin heats or cools the skin and the body secretes oil (from glands) contains sensory nerves a) detects pressure b) detects pain c) detects temperature hair coat, mane and tail grow from the skin hooves are composed of specialized form of skin over a bone framework Epidermis thin outer layer Dermis Veterinary (A) – Instructor’s Guide -- 30 Structures it contains Hair coat function Diseases and conditions that affect the skin thicker layer containing most skin structures 3. Subcutaneus thin layer of fatty material just over muscles 1. Apocrine (sweat glands) 2. Sebaceous glands (secrete sebum (skin oil) 3. Hair follicles including a) papilla or root b) hair shaft c) tiny erector pili muscle d) can cause hair to stand up 4. Blood vessels and nerves 5. Panniculus muscle large, thin sheet of muscle which lies under the skin allows horse to twitch skin to remove flies and shiver to create heat 1. protection from cold dampness insects 2. specialized hair features (fetlocks, hair inside ears, whiskers, mane and tail) have protective roles 3. winter coat is longer and thicker contains extra long guard hairs permit water to run off skin produces extra sebum to help to waterproof skin and hair coat 4. hair standing erect (staring coat) indicates a horse trying to keep warm (either sick or with chills) a) increases loft b) traps air close to skin c) increases warmth hypothalamus (part of brain affected by the shortening and lengthening of daylight and temperature) controls growth and shedding of the winter coat Warts (papilloma virus) Sarcoid tumors Dermatiphilosis (rainrot, rain scald, scratches, grease heel) Ringworm Veterinary (A) – Instructor’s Guide -- 31 Part VI – Anatomy Purpose 1. Know and discuss the location and function of main anatomical features of the skeleton, arteries and muscles. Teaching Suggestions 1. Review materials in tables. 2. Students should already be somewhat familiar with much of this content so see how much they can tell you. Skeletal System (USAB 223) 1. support Functions 2. protection of vital organs 3. movement Bones Function Cartilage USAB 225 Function Joints USAB 224 Types Structure 1. 2. 3. 4. 5. 6. joints held together by ligaments permit movement muscles attached to bone by tendons move the bones 206 bones contain protein and mineral (Ca and Ph) framework of the body levers for movement attachment points for muscles protection for vital organs protection for spinal cord production of red blood cells 1. 2. 3. 1. smooth firm flexible makes up some structures ears nose 2. covers articular surface of bones in joints bones move smoothly absorb shock 3. matrix of form in the immature bone turns to hard bone as animal matures a) joints of skull b) epiphyseal plates (growth plates at end of long bones) where bones meet 1. immovable (joints of skull) 2. permit little movement 3. permit wide range of movement 1. ligaments hold joint together 2. joint capsule enclose moveable joint a ligament containing synovial fluid (joint oil) lubricates the joint 3. bursa fluid filled capsule protects a joint or a prominent bone end (elbow or hock) Veterinary (A) – Instructor’s Guide -- 32 Diagram Axial Skeleton USAB 225 Appendicular Skeleton USAB 225 Diseases of the skeletal system 1. Skull a) mandible (lower jaw bone) b) teeth c) hyoid bone 2. Vertebral column a) cervical vertebrae (7) b) atlas (the first one) c) axis (the second one) d) thoracic vertebrae (18) e) lumbar vertebrae (6) f) sacral vertebrae (5) fused together in the sacrum g) coccygeal (tail) vertebrae (18-23) 3. rib cage a) 18 ribs each connected to a thoracic vertebra b) sternum (breastbone) the front and hind limbs 1. 2. 3. 4. osteomalacia epiphysitis rickets arthritis Veterinary (A) – Instructor’s Guide -- 33 Diagram Muscular System USAB 226 1. made of muscle fibers Muscles arranged in bundles 2. controlled by motor nerves stimulate them to contract (fire) by electrochemical reaction a) muscle shortens b) pull the more muscle fibers involved the stronger the pull 3. usually work in pairs a) one muscle group flexes (bends) b) one muscles group extends (straightens) 1. cardiac Muscle Types found in heart 2. smooth found in autonomic nervous system (e.g., digestive tract) 3. skeletal move bones usually acting in pairs Veterinary (A) – Instructor’s Guide -- 34 Tendons Fascia USAB 227 strong fibrous connective tissue connects muscle to bones 1. various shapes a) wide flat sheets b) thick bands c) long cables 2. tendon sheath protects a tendon where it crosses a joint contains synovial fluid which lubricates it 1. fibrous connective tissue thin tough 2. encases muscles and lies in wide sheets 3. some muscles and tendons are attached to fascia especially areas like the back Major Muscle Groups (USAB 227-229) Muscle Masseter Muscles of Head and Neck Brachiocephalus Rhomboid and Splenius Trapezius Back and Trunk Muscles Longissimus dorsi Latissimus dorsi Internal and external obliques Abdominals (abdominal obliques and rectus abdominus) Iliopsoas Location large muscle of the jowl Function used in chewing long muscle running from poll to upper arm at the top of the neck running to shoulder blade at the top of the neck and behind the withers deep muscles of the back running along back and down the barrel to the back of the shoulder blade muscles of the ribs helps to extend and raise the forearm well developed when the horse carries his head and neck well carries the saddle deep muscle from supports the saddle aid in breathing aid in breathing help to raise the back and bring hindquarters under engagement of Veterinary (A) – Instructor’s Guide -- 35 Hindquarter Muscles Vastus Gluteal muscles Quadriceps group Hamstring group Achilles tendon Foreleg Muscles Triceps Extensor muscles of lower leg Flexor muscles of the lower leg underside of lumbar spine to femur (thighbone) and pelvis muscle from hip to stifle large muscles of hip muscles on the front of the femur around the back of the hindquarters large tendon above the hock large muscle from elbow to bottom of shoulder blade muscles of the forearm (front) muscles of the forearm (back) hindquarters flexes hind leg extend the femur flex the hind leg and bring it forward extend the hind leg and push the body forward extends the hock straightens elbow and foreleg extend the lower leg flex the joints of the lower leg Part VII – Pre-purchase Exam Purpose 1. Know some of the things a veterinarian will consider in an pre-purchase exam Teaching Suggestions 1. Ask students if they have ever observed a pre-purchase exam. 2. What sort of things do they think it would be important to know in a horse they were considering purchasing. Pre-purchase examination (VN 663) Notes the examination is made for a specific purpose in mind veterinarian will provide an opinion on the significance of the fault in relation to the purpose for which the animal is being purchased always mention vices to the veterinarian if you have noticed them seller in under obligation to disclose any vices that they are aware of Common conditions rendering a horse unfit for purchase (VN 663) Potential Conditions Defects of eye abscence of an eye collapse of an eye corneal opacity cataract paralysis of the iris blindness periodic ophthalmia Defects of wind whistling or roaring chronic obstructive pulmonary disease coughing bleeding (“exercise induced pulmonary haemorrhage” or “epitaxisis”) Defective limb lameness action action may be peculiar or objectionable but when due to conformation does not amount to lameness stringhalt Veterinary (A) – Instructor’s Guide -- 36 Potential Conditions shivering thickening or inflammation of tendons (especially the flexor tendons of forelimbs) considered serious osteoarthrosis of joints incoordination of hindlimbs or all four limbs diseases of heart, respiratory and digestive systems, urinary and genital organis, skin, feet and eye dribbling of urine may indicate calculus or gritty accumulation in the bladder or congenital malformation diarrhea must be notes (even if it may disappear later) devalue a horse but may be of no consequence if horse is not lame may impair the natural usefulness of the animal matter of taste or opinion Existing diseases or effects of disease or accident Blemishes Vices and bad habits Defective conformation Veterinary (A) – Instructor’s Guide -- 37 TOPIC– B Homework Key 22 marks total 1. What are three routes of disease entry (3) 1. Mouth 2. nostrils 3. skin 4. urinogenital tract 5. conjunctiva or eyelids 2. Which is more easily carried in the air – virus or bacteria and why.(1) Virus it is much smaller than bacteria 3. What are the six disease processes (6) 1. shock 2. fever 3. dehydration 4. inflammation 5. edema 6. arthritis 4. What are five methods of administering drugs (5) 1. Orally (by mouth) 2. Locally (directly to skin, eye, nostrils etc.) 3. Parenterally (injection by qualified person) 4. Stomach tube (by vet) (VN – 478) 5. Inhalation: steam vapours (VN – 481) 6. Enema: inserted into rectum (VN – 481) 7. Intravaginal or intrauterine administration: directly into vagina or uterus(VN – 482) 5. What is a fecal count including what it does and does not show (3) a microscopic examination of a fecal sample shows the number and types of parasites present in the horse only show how many mature, egg laying parasites are present does not indicate levels of migrating larvae (much more damaging) Describe the following parts of the respiratory system (4) Nasal Cavities Nasal Turbinates Epiglottis Alveoli air passages lined with mucus membrane separated from the mouth by the hard palate and (farther back) the soft palate very thin curling bones inside the nasal passages covered with mucus membrane b) helps trap dust (MH 431) large surface area helps to warm incoming air before it reaches the lungs flap that covers the glottis (opening into the windpipe) when the horse swallows small air sacs only one cell in thickness like bunches of grapes at the end of the bronchioles carbon dioxide and oxygen are exchanged through the wall of the alveoli into the many blood vessels of the lungs “gaseous exchange (MH 431) Veterinary (A) – Homework Key -- 1 TOPIC – B Student’s Guide Part I – Disease -- Fundamentals Purpose 1. 2. 3. 4. Know the three primary routes of entry of disease Know the difference between a contagious and an infectious disease Know the difference between a viral and a bacterial disease Know the disease processes including shock, fever, dehydration, inflammation, edema and arthritis Routes of disease entry Routes of entry VN 397 Why is this useful VN 400 Contagious vs. infectious Description Contagious Examples KYH KYH MH MH MH 345 KYH 74 Veterinary (A) – Student’s Guide -- 1 Description Infectious Examples KYH KYH MH MH MH 345 KYH 74 Bacterial vs. viral Description Examples Virus KYH 75 Bacteria KYH 72 VN 398 Veterinary (A) – Student’s Guide -- 2 Other terminology Infection KYH 72 Communicable Virulence/ pathogenicity VN 397 aerobic anaerobic Disease processes What is a “disease process” USAB 353 Veterinary (A) – Student’s Guide -- 3 Why know what they are? USAB 353 What are the six disease processes? USAB 354 Shock Notes USAB 354 Signs USAB 354 Causes USAB 354 Treatment USAB 354 Veterinary (A) – Student’s Guide -- 4 Fever Notes USAB 354 Causes USAB 354 Symptoms USAB 354 Treatment USAB 354 Dehydration Notes USAB 355 Causes USAB 355 KYH 116/117 Veterinary (A) – Student’s Guide -- 5 Symptoms USAB 355 KYH 117 Treatment USAB 355 Inflammation Notes USAB 355 Process USAB 355 Purpose USAB 356 Causes USAB 355 Veterinary (A) – Student’s Guide -- 6 Symptoms USAB 356 Problems with excessive inflammation USAB 356 Causes of excessive inflammation USAB 356 Treating USAB 356 Edema Notes USAB 356 Causes USAB 356 Veterinary (A) – Student’s Guide -- 7 Symptoms USAB 356 Treatments USAB 356 Arthritis Notes USAB 357 Two types Symptoms USAB 357 Types Traumatic Treatment USAB 357 Veterinary (A) – Student’s Guide -- 8 Septic Symptoms USAB 357 Treatment Degenerative Process USAB 357 Treatment Part II –Disease -- Specifics Purpose 1. Know the cause, symptoms, treatments and system affected for various diseases including botulism, strangles, roaring, rhinopneumonitis, CEM, EIA, rabies, Equine Encephalomyletis and EVA Botulism USAB 358 Notes USAB 358 System affected USAB 358 Cause USAB 358 Veterinary (A) – Student’s Guide -- 9 Symptoms USAB 358 Prevention USAB 358 Treatment USAB 358 Equine Infectious Anemia (EIA/Swamp fever) Notes USAB 359 VN 430 System affected Cause Veterinary (A) – Student’s Guide -- 10 Symptoms USAB 359 VN 430 Prevention USAB 359 VN 430 Treatments USAB 359 VN 430 Equine Encephalomyletis (sleeping sickness, EEE, WEE, VEE) USAB 359 Notes USAB 359 System affected USAB 359 Cause USAB 359 Veterinary (A) – Student’s Guide -- 11 Symptoms USAB 359 VN 431 Prevention USAB 359 VN 431 Treatments VN 431 Equine Viral Arteritis (EVA, pinkeye) Notes USAB 360 System affected USAB 360 Cause USAB 360 Veterinary (A) – Student’s Guide -- 12 Symptoms USAB 360 Prevention USAB 360 Rabies USAB 362 Notes USAB 362 System affected USAB 362 Cause USAB 362 Symptoms USAB 362 Veterinary (A) – Student’s Guide -- 13 Prevention USAB 362 Treatments USAB 362 Strangles (distemper) Notes USAB 362 VN 411 KYH 76 System affected USAB 362 Cause USAB 362 Symptoms USAB 362 VN 411 KYH 76 Veterinary (A) – Student’s Guide -- 14 Prevention USAB 362 VN 414 Treatments USAB 362 VN 414 KYH 78 Roaring USAB 362 Notes USAB 362 KYH 107/8 System affected USAB 362 Cause USAB 362 KYH 107 NZ2 238 Symptoms USAB 362 KYh 108 Veterinary (A) – Student’s Guide -- 15 Things it can be confused with KYH 108 Prevention KYH 108 Treatments USAB 362 Equine Viral Rhinopneumonitis (EVR) Notes USAB 360 KYH 86 System affected USAB 362 Cause USAB 362 Veterinary (A) – Student’s Guide -- 16 Symptoms USAB 362 KYH 86 Prevention USAB 362 VN 426 Treatments USAB 362 KYH 87 Contagious Equine Metritis (CEM, Taylorella equigenitalis) VN 420 Notes VN 420 KYH 81 System affected VN 420 Cause VN 420 Veterinary (A) – Student’s Guide -- 17 Symptoms VN 420 Prevention VN 420 Treatments VN 420 Stallions Part III – Supplies and Techniques Purpose 1. Know how to administer various medications 2. Know the names and uses of various drugs Administering medication Methods of administering (7) MH 348 KYH 195 VN 477-482 Veterinary (A) – Student’s Guide -- 18 Medication Notes Notes USAB 363 Guidelines for using medications safely Terminology and drug types Note USAB 364 anti-pyretic USAB 366 analgesic narcotic Veterinary (A) – Student’s Guide -- 19 steroids Non-narcotic, nonsteroidal Analgesics Examples Non-steroidal antiinflammatories (NSAIDS NSAIDs Notes USAB 366 Use USAB 366 Problems USAB 366 Veterinary (A) – Student’s Guide -- 20 Example USAB 366 Tranquilizers USAB 364 Notes USAB 364 Use USAB 364 Results/precautions USAB 364 Examples USAB 364 Veterinary (A) – Student’s Guide -- 21 Antibiotics Notes USAB 368 Use USAB 368 Results/precautions USAB 368 Examples USAB 368 Veterinary (A) – Student’s Guide -- 22 Specific drugs and medications Drug Type Acepromazine (PromAce, Promazine Granules) Action Administration Cautions Use USAB 364 Xylazine (Rompun) USAB 365 Dormosedan USAB 365 Veterinary (A) – Student’s Guide -- 23 Drug Banamine (Flunixin Meglumine) Type Action Administration Cautions Use USAB 365 Dipyrone USAB 366 Torbugesic USAB 366 Phenylbutazone (bute, probute) USAB 366 Veterinary (A) – Student’s Guide -- 24 Drug Aspirin USAB 367 Type Action Administration Cautions Use Ketoprofen (Ketofen) USAB 367 Dexamethazone (azium) and other corticosteroids USAB 367 Veterinary (A) – Student’s Guide -- 25 Part IV – Parasite Control Purpose 1. Know the principles of parasite control in the horse/herd 2. Know the names of recent drugs for parasite control and discuss their use and rotation 3. Know the term “fecal count” and how it relates to parasite management Notes Components of a good control system USAB 345 Considerations for a good control system USAB 345 Deworming Schedule USAB 345 MH 357 Choosing a product USAB 345 MH 357 Administering dewormers (3) USAB 348 Veterinary (A) – Student’s Guide -- 26 Rotation of wormers Notes USAB 348 MH 357 Testing for Parasites Fecal parasite count USAB 349 Scheduling USAB 349 Reducing Exposure to Internal Parasites Notes USAB 349 Basic Principles USAB 349 Veterinary (A) – Student’s Guide -- 27 Recommendations USAB 349 Veterinary (A) – Student’s Guide -- 28 Deworming Products Drug Brand Name Dichlorvos Cutter Dichlorvos Horse Wormer Febentel Rintal Combotel Negabot-Plus Fenbendazole Panacure Form Effective Against Comments Veterinary (A) – Student’s Guide -- 29 Drug Telmin, Telmin B Brand Name Ivermectin Equalvan Equimectrin Zimectrin Piperazine Piperazine 17% or 34% Peperazing water wormer Pipfuge Pip-Pop 320 Oxfendazole Benzelmin Benzelmin plus Form Effective Against Comments Veterinary (A) – Student’s Guide -- 30 Drug Oxibendazole Brand Name Anthelcide Eq Equipar R Pyrantel Pamoate Imathal Strongid Pyrantel Tartrate Banminth Purina Horse and Colt Wormer Strongid C Thiabendazole Equizole Equizole A Form Effective Against Comments Veterinary (A) – Student’s Guide -- 31 Drug Trichlorfon Brand Name Combot Liquid Combot Paste Negabot Paste Telmin B Benexelmin Plus Combotel Dyrex Moxidectrin Quest Quest gel Information from Quest label not a required reading source Form Gel Paste Effective Against Large and small strongyles Encysted cyathostomes Ascarids Pin worms Hair worms Large mouth stomach worms Bots Comments Extreme caution should be used when administering the product to foals, young and miniature horses, as overdosage may result in serious adverse reactions. Do not use in horses or ponies intended for food. For animals 4 months of age or older Transient depression, ataxia and recumbency may be seen when very young or debilitated animals are treated. Reproductive safety studies demonstrate a wide margin of safety when the product is used in the treatment of estrual and pregnant mares and breeding stallions Veterinary (A) – Student’s Guide -- 32 Part V – Systems Purpose 1. Know the primary parts, functions and diseases of the respiratory, circulatory, lymphatic,, nervous and urinary systems 2. Know the functions/purpose of the skin Circulatory System Function (3) USAB 230 Blood Components (3) USAB 230 Types of blood (2) USAB 230 Vessels USAB 230 Arteries Veterinary (A) – Student’s Guide -- 33 Veins Capillaries The Heart USAB 229 Chambers USAB 230 Flow Conditioning the heart USAB 232 Veterinary (A) – Student’s Guide -- 34 Diseases of the lymphatic and circulatory system USAB 230 VN 68 Lymphatic System USAB 231 Notes USAB 231 VN 66/7 Function (4) MH 431 Lymph USAB 230 Lymph vessels USAB 230 Lymph nodes USAB 230 MH 43 Veterinary (A) – Student’s Guide -- 35 Respiratory System USAB 233 Function USAB 233 MH 341 Breathing USAB 235 Notes USAB 235 Diseases USAB 236 Upper Respiratory Tract Nostrils USAB 233 Nasal Cavities USAB 233 Veterinary (A) – Student’s Guide -- 36 Nasal Turbinates USAB 234 MH 431 Sinuses USAB 234 Pharynx (throat) USAB 234 Larynx (voice box) USAB 234 KYH 107 Epiglottis USAB 234 Trachea(windpipe) USAB 234 Veterinary (A) – Student’s Guide -- 37 Lower Respiratory Tract Lungs USAB 234 Bronchi USAB 234 Alveoli USAB 235 Pleura USAB 235 Diaphragm USAB 235 Urinary System USAB 240 Function (4) USAB 240 Veterinary (A) – Student’s Guide -- 38 Kidneys USAB 235 Ureters USAB 236 Urinary bladder USAB 236 Urethra USAB 236 Notes USAB 236 Nervous System Function (3) USAB 242 Veterinary (A) – Student’s Guide -- 39 Central Nervous System USAB 242 Peripheral Nerves USAB 242 Autonomic Nervous System USAB 243 Nerve cells and their function USAB 243 Notes USAB 243 Diseases USAB 243 Veterinary (A) – Student’s Guide -- 40 The Skin USAB 249 Notes USAB 249 Function (8) USAB 249 Layers (3) USAB 249 Structures it contains (5) USAB 249 Hair coat function (4) USAB 250 Veterinary (A) – Student’s Guide -- 41 Diseases and conditions that affect the skin USAB 250 Part VI – Anatomy Purpose 1. Know and discuss the location and function of main anatomical features of the skeleton, arteries and muscles. Skeletal System Functions (3) USAB 223 Bones USAB 224 Function (6) Cartilage USAB 225 Veterinary (A) – Student’s Guide -- 42 Function (3) Joints USAB 224 Types Structure Parts of the Axial Skeleton (3) USAB 225 Appendicular Skeleton USAB 225 Veterinary (A) – Student’s Guide -- 43 Diseases of the skeletal system Muscular System Muscles USAB 227 Muscle Types (3) USAB 226 Tendons USAB 227 Fascia USAB 227 Veterinary (A) – Student’s Guide -- 44 Major Muscle Groups (USAB 227-229) Muscle Masseter Muscles of Head and Neck Location Function USAB 227 Brachiocephalus Rhomboid and Splenius Trapezius Back and Trunk Muscles Longissimus dorsi USAB 227 Latissimus dorsi Veterinary (A) – Student’s Guide -- 45 Muscle Internal and external obliques Location Function Abdominals (abdominal obliques and rectus abdominus) Iliopsoas Hindquarter Muscles Vastus USAB 228 Gluteal muscles Quadriceps group Hamstring group Veterinary (A) – Student’s Guide -- 46 Muscle Achilles tendon Foreleg Muscles Location Function Triceps USAB 229 Extensor muscles of lower leg Flexor muscles of the lower leg Veterinary (A) – Student’s Guide -- 47 Part VII – Pre-purchase Exam Purpose 1. Know some of the things a veterinarian will consider in an pre-purchase exam Pre-purchase examination (VN 663) Notes VN 663 Common conditions rendering a horse unfit for purchase (VN 663) Potential Conditions Defects of eye Defects of wind Defective limb action Existing diseases or effects of disease or accident Veterinary (A) – Student’s Guide -- 48 Potential Conditions Blemishes Vices and bad habits Defective conformation Veterinary (A) – Student’s Guide -- 49 TOPIC – B Homework 1. What are three routes of disease entry (3) 2. Which is more easily carried in the air – virus or bacteria and why.(1) 3. What are the six disease processes (6) 4. What are five methods of administering drugs (5) 5. What is a fecal count including what it does and does not show (3) 6. Describe the following parts of the respiratory system (4) Nasal cavities Nasal turbinates Epiglottis Alveoli Name: Veterinary (A) – Student Homework -- 1