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Supplementary Table 1: Predictions for human proteins based on the complete GO annotation data set. The column denoted by “Protein (H)” contains a human protein for which we predict a GO term. The column denoted by “Protein (Y)” contains a yeast protein that is aligned to the corresponding human protein and that is annotated with the GO term that we assign to the human protein. The predicted GO term is given in the column denoted by “GO term accession.” Its name and ontology (i.e., molecular function (F), biological process (P), or cellular component (C)) are given in the columns denoted by “GO name” and “GO ontology,” respectively. Protein(H) Protein(Y) GO term accession GO name Go ontology C9orf16 CMP2 GO:0005737 cytoplasm C C9orf16 CMP2 GO:0005955 calcineurin complex C OCM TFC1 GO:0000127 transcription factor TFIIIC complex C OCM TFC1 GO:0005634 nucleus C TRAP1 PRP39 GO:0005634 nucleus C TRAP1 PRP39 GO:0000243 commitment complex C TRAP1 PRP39 GO:0005685 snRNP U1 C TRAP1 PRP39 GO:0005622 intracellular C MKRN1 GLC8 GO:0005737 cytoplasm C MKRN1 GLC8 GO:0005634 nucleus C EXOSC8 MRPL20 GO:0005840 ribosome C EXOSC8 MRPL20 GO:0005739 mitochondrion C EXOSC8 MRPL20 GO:0005762 mitochondrial large ribosomal subunit C EXOSC8 MRPL20 GO:0030529 ribonucleoprotein complex C TLX2 DBP7 GO:0005634 nucleus C TLX2 DBP7 GO:0005730 nucleolus C FANCD2 CCL1 GO:0000109 nucleotide-excision repair complex C FANCD2 CCL1 GO:0005739 mitochondrion C FANCD2 CCL1 GO:0005675 holo TFIIH complex C ARID4B YLL023C GO:0016021 integral to membrane C ARID4B YLL023C GO:0016020 membrane C ARID4B YLL023C GO:0005783 endoplasmic reticulum C 6-Sep ORC2 GO:0005634 nucleus C 6-Sep ORC2 GO:0005664 nuclear origin of replication recognition complex C 6-Sep ORC2 GO:0005656 pre-replicative complex C 6-Sep ORC2 GO:0000808 origin recognition complex C 6-Sep ORC2 GO:0031261 DNA replication preinitiation complex C IFIT3 SCS2 GO:0005635 nuclear envelope C IFIT3 SCS2 GO:0005783 endoplasmic reticulum C IFIT3 SCS2 GO:0005634 nucleus C IFIT3 SCS2 GO:0016020 membrane C IFIT3 SCS2 GO:0031965 nuclear membrane C IFIT3 SCS2 GO:0030176 integral to endoplasmic reticulum membrane C IFIT3 SCS2 GO:0005934 cellular bud tip C IFIT3 SCS2 GO:0016021 integral to membrane C IFIT2 HSK3 GO:0005819 spindle C IFIT2 HSK3 GO:0042729 IFIT2 HSK3 GO:0005634 nucleus C IFIT2 HSK3 GO:0005874 microtubule C IFIT2 HSK3 GO:0000776 kinetochore C IFIT2 HSK3 GO:0000777 condensed chromosome kinetochore C USP21 NNF2 GO:0005624 membrane fraction C USP21 NNF2 GO:0016021 integral to membrane C USP21 NNF2 GO:0016020 membrane C USP21 NNF2 GO:0005783 endoplasmic reticulum C USP20 YRB30 GO:0005737 cytoplasm C USP20 YRB30 GO:0005634 nucleus C CHIC2 RPC82 GO:0005737 cytoplasm C CHIC2 RPC82 GO:0005634 nucleus C CHIC2 RPC82 GO:0005666 DNA-directed RNA polymerase III complex C MAP3K9 ZPR1 GO:0005737 cytoplasm C MAP3K9 ZPR1 GO:0005634 nucleus C JMJD5 UBA2 GO:0005634 nucleus C JMJD5 UBA2 GO:0031510 SUMO activating enzyme complex C C10orf119 ERG1 GO:0016021 integral to membrane C C10orf119 ERG1 GO:0016020 membrane C C10orf119 ERG1 GO:0005811 lipid particle C C10orf119 ERG1 GO:0005792 microsome C C10orf119 ERG1 GO:0005783 endoplasmic reticulum C RGS6 HOS4 GO:0034967 Set3 complex C ODC1 CMK2 GO:0005737 cytoplasm C MAPK3 DBP9 GO:0005634 nucleus C MAPK3 DBP9 GO:0005730 nucleolus C FOXRED1 YDR061W GO:0005739 mitochondrion C WSB1 INO80 GO:0005634 nucleus C WSB1 INO80 GO:0031011 Ino80 complex C NME5 PCL7 GO:0005737 cytoplasm C NME5 PCL7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex C NME5 PCL7 GO:0005634 nucleus C OFD1 CSR1 GO:0005737 cytoplasm C OFD1 CSR1 GO:0005792 microsome C OFD1 CSR1 GO:0005829 cytosol C OFD1 CSR1 GO:0005811 lipid particle C OFD1 CSR1 GO:0005739 mitochondrion C OFD1 CSR1 GO:0005768 endosome C SURF2 DRE2 GO:0005737 cytoplasm C C SURF2 DRE2 GO:0005758 mitochondrial intermembrane space C SURF2 DRE2 GO:0005829 cytosol C PHKG2 ARC15 GO:0005737 cytoplasm C PHKG2 ARC15 GO:0005856 cytoskeleton C PHKG2 ARC15 GO:0030479 actin cortical patch C PHKG2 ARC15 GO:0031315 extrinsic to mitochondrial outer membrane C PHKG2 ARC15 GO:0005885 Arp2/3 protein complex C PHKG2 ARC15 GO:0005938 cell cortex C PHKG2 ARC15 GO:0044448 cell cortex part C BCL7A YER077C GO:0005739 mitochondrion C CTDSPL SEY1 GO:0005737 cytoplasm C CTDSPL SEY1 GO:0016021 integral to membrane C CTDSPL SEY1 GO:0016020 membrane C CTDSPL SEY1 GO:0005783 endoplasmic reticulum C CTDSPL SEY1 GO:0032541 cortical endoplasmic reticulum C NKIRAS2 URH1 GO:0005737 cytoplasm C NKIRAS2 URH1 GO:0005634 nucleus C MTM1 YER140W GO:0016021 integral to membrane C MTM1 YER140W GO:0016020 membrane C MTM1 YER140W GO:0005739 mitochondrion C PCYT2 SDH1 GO:0005743 mitochondrial inner membrane C PCYT2 SDH1 GO:0016020 membrane C PCYT2 SDH1 GO:0005749 mitochondrial respiratory chain complex II C PCYT2 SDH1 GO:0005739 mitochondrion C PCYT2 SDH1 GO:0031966 mitochondrial membrane C LTB TRX2 GO:0005737 cytoplasm C LTB TRX2 GO:0005794 Golgi apparatus C LTB TRX2 GO:0000324 fungal-type vacuole C LTB TRX2 GO:0005634 nucleus C LTB TRX2 GO:0016020 membrane C LTB TRX2 GO:0005829 cytosol C ZFAND5 YMR310C GO:0005634 nucleus C TAF1L SQT1 GO:0005737 cytoplasm C TAF1L SQT1 GO:0005829 cytosol C TAF1L SQT1 GO:0022626 cytosolic ribosome C CHERP RPL37A GO:0005737 cytoplasm C CHERP RPL37A GO:0030529 ribonucleoprotein complex C CHERP RPL37A GO:0005840 ribosome C CHERP RPL37A GO:0005622 intracellular C CHERP RPL37A GO:0022625 cytosolic large ribosomal subunit C TPD52L1 CDC3 GO:0031105 septin complex C TPD52L1 CDC3 GO:0005628 prospore membrane C TPD52L1 CDC3 GO:0000144 cellular bud neck septin ring C TPD52L1 CDC3 GO:0001400 mating projection base C TPD52L1 CDC3 GO:0016020 membrane C TPD52L1 CDC3 GO:0005619 ascospore wall C TPD52L1 CDC3 GO:0005935 GALNT5 NIF3 GO:0005737 cytoplasm C GALNT5 NIF3 GO:0005739 mitochondrion C CXorf26 URA10 GO:0005737 cytoplasm C ASMTL RNH202 GO:0005634 nucleus C ASMTL RNH202 GO:0032299 ribonuclease H2 complex C MAGEA12 AIM45 GO:0005759 mitochondrial matrix C MAGEA12 AIM45 GO:0005739 mitochondrion C LRP4 TAH18 GO:0005739 mitochondrion C DDX24 RPL11B GO:0005737 cytoplasm C DDX24 RPL11B GO:0030529 ribonucleoprotein complex C DDX24 RPL11B GO:0005840 ribosome C DDX24 RPL11B GO:0005622 intracellular C DDX24 RPL11B GO:0022625 cytosolic large ribosomal subunit C CCND1 RPL12B GO:0005737 cytoplasm C CCND1 RPL12B GO:0030529 ribonucleoprotein complex C CCND1 RPL12B GO:0005840 ribosome C CCND1 RPL12B GO:0005622 intracellular C CCND1 RPL12B GO:0022625 cytosolic large ribosomal subunit C PCID2 BDH1 GO:0005737 cytoplasm C ALS2CR12 TFC6 GO:0000127 transcription factor TFIIIC complex C ALS2CR12 TFC6 GO:0005634 nucleus C PLCG1 RPS9B GO:0005737 cytoplasm C PLCG1 RPS9B GO:0032040 small-subunit processome C PLCG1 RPS9B GO:0015935 small ribosomal subunit C PLCG1 RPS9B GO:0005730 nucleolus C PLCG1 RPS9B GO:0005634 nucleus C PLCG1 RPS9B GO:0030686 90S preribosome C PLCG1 RPS9B GO:0005622 intracellular C PLCG1 RPS9B GO:0005840 ribosome C PLCG1 RPS9B GO:0030529 ribonucleoprotein complex C PLCG1 RPS9B GO:0022627 cytosolic small ribosomal subunit C PRX IMH1 GO:0005737 cytoplasm C PRX IMH1 GO:0005794 Golgi apparatus C PRX IMH1 GO:0005829 cytosol C PRX IMH1 GO:0016020 membrane C C PRCC YLR132C GO:0005737 cytoplasm C PRCC YLR132C GO:0005634 nucleus C PRCC YLR132C GO:0005739 mitochondrion C MTPN GND1 GO:0005737 cytoplasm C MTPN GND1 GO:0005739 mitochondrion C CUL4B PIH1 GO:0005737 cytoplasm C CUL4B PIH1 GO:0005634 nucleus C CUL4B PIH1 GO:0005732 small nucleolar ribonucleoprotein complex C DDX1 MRPS9 GO:0030529 ribonucleoprotein complex C DDX1 MRPS9 GO:0005622 intracellular C DDX1 MRPS9 GO:0005840 ribosome C DDX1 MRPS9 GO:0005739 mitochondrion C DDX1 MRPS9 GO:0005763 mitochondrial small ribosomal subunit C PSKH1 RNT1 GO:0005654 nucleoplasm C PSKH1 RNT1 GO:0005622 intracellular C PSKH1 RNT1 GO:0005730 nucleolus C UBL5 BCY1 GO:0030552 cAMP binding F UBL5 BCY1 GO:0008603 cAMP-dependent protein kinase regulator activity F UBL5 BCY1 GO:0000166 nucleotide binding F UBL5 BCY1 GO:0004862 cAMP-dependent protein kinase inhibitor activity F UBL5 BCY1 GO:0004691 cAMP-dependent protein kinase activity F UBL5 BCY1 GO:0004690 cyclic nucleotide-dependent protein kinase activity F C9orf16 CMP2 GO:0016787 hydrolase activity F C9orf16 CMP2 GO:0004721 phosphoprotein phosphatase activity F C9orf16 CMP2 GO:0005516 calmodulin binding F C9orf16 CMP2 GO:0005506 iron ion binding F C9orf16 CMP2 GO:0046872 metal ion binding F C9orf16 CMP2 GO:0008270 zinc ion binding F MFRP TFS1 GO:0005543 phospholipid binding F MFRP TFS1 GO:0008289 lipid binding F MFRP TFS1 GO:0030414 peptidase inhibitor activity F MFRP TFS1 GO:0004867 serine-type endopeptidase inhibitor activity F NRSN2 PDR17 GO:0008526 phosphatidylinositol transporter activity F MKRN1 GLC8 GO:0008047 enzyme activator activity F EXOSC8 MRPL20 GO:0003735 structural constituent of ribosome F MFAP4 DAM1 GO:0005200 structural constituent of cytoskeleton F DLK1 VMA4 GO:0015078 hydrogen ion transmembrane transporter activity F DLK1 VMA4 GO:0046961 F NPTX2 ATP16 GO:0016787 proton-transporting ATPase activity, rotational mechanism hydrolase activity NPTX2 ATP16 GO:0015078 hydrogen ion transmembrane transporter activity F NPTX2 ATP16 GO:0046961 proton-transporting ATPase activity, rotational F F mechanism NPTX2 ATP16 GO:0046933 F GO:0016251 hydrogen ion transporting ATP synthase activity, rotational mechanism general RNA polymerase II transcription factor activity FANCD2 CCL1 FANCD2 CCL1 GO:0016538 cyclin-dependent protein kinase regulator activity F KREMEN1 DBP6 GO:0016787 hydrolase activity F KREMEN1 DBP6 GO:0008026 ATP-dependent helicase activity F KREMEN1 DBP6 GO:0004004 ATP-dependent RNA helicase activity F KREMEN1 DBP6 GO:0004386 helicase activity F KREMEN1 DBP6 GO:0003723 RNA binding F KREMEN1 DBP6 GO:0003676 nucleic acid binding F KREMEN1 DBP6 GO:0000166 nucleotide binding F KREMEN1 DBP6 GO:0005524 ATP binding F CHIC2 RPC82 GO:0003899 DNA-directed RNA polymerase activity F CHIC2 RPC82 GO:0008270 zinc ion binding F CHIC2 RPC82 GO:0003677 DNA binding F JMJD5 UBA2 GO:0019948 SUMO activating enzyme activity F JMJD5 UBA2 GO:0008641 small protein activating enzyme activity F JMJD5 UBA2 GO:0000166 nucleotide binding F JMJD5 UBA2 GO:0003824 catalytic activity F JMJD5 UBA2 GO:0005488 binding F JMJD5 UBA2 GO:0016874 ligase activity F JMJD5 UBA2 GO:0005524 ATP binding F C10orf119 ERG1 GO:0008144 drug binding F C10orf119 ERG1 GO:0004506 squalene monooxygenase activity F C10orf119 ERG1 GO:0050660 FAD binding F C10orf119 ERG1 GO:0016491 oxidoreductase activity F NEFH ORC4 GO:0003688 DNA replication origin binding F NEFH ORC4 GO:0003677 DNA binding F FOXRED1 YDR061W GO:0000166 nucleotide binding F FOXRED1 YDR061W GO:0017111 nucleoside-triphosphatase activity F FOXRED1 YDR061W GO:0016887 ATPase activity F FOXRED1 YDR061W GO:0005524 ATP binding F WSB1 INO80 GO:0016787 hydrolase activity F WSB1 INO80 GO:0016887 ATPase activity F WSB1 INO80 GO:0000166 nucleotide binding F WSB1 INO80 GO:0003676 nucleic acid binding F WSB1 INO80 GO:0003677 DNA binding F WSB1 INO80 GO:0004386 helicase activity F WSB1 INO80 GO:0005524 ATP binding F CRISP3 MCM5 GO:0009378 four-way junction helicase activity F CRISP3 MCM5 GO:0042623 ATPase activity, coupled F F CRISP3 MCM5 GO:0004003 ATP-dependent DNA helicase activity F CRISP3 MCM5 GO:0003682 chromatin binding F CRISP3 MCM5 GO:0017111 nucleoside-triphosphatase activity F CRISP3 MCM5 GO:0000166 nucleotide binding F CRISP3 MCM5 GO:0003688 DNA replication origin binding F CRISP3 MCM5 GO:0016887 ATPase activity F CRISP3 MCM5 GO:0003677 DNA binding F CRISP3 MCM5 GO:0043138 3'-5' DNA helicase activity F CRISP3 MCM5 GO:0005524 ATP binding F OFD1 CSR1 GO:0008526 phosphatidylinositol transporter activity F LFNG KKQ8 GO:0016301 kinase activity F LFNG KKQ8 GO:0000166 nucleotide binding F LFNG KKQ8 GO:0004674 protein serine/threonine kinase activity F LFNG KKQ8 GO:0016740 transferase activity F LFNG KKQ8 GO:0004672 protein kinase activity F LFNG KKQ8 GO:0005524 ATP binding F MORF4L2 MRP21 GO:0003735 structural constituent of ribosome F A1BG MCM6 GO:0043566 structure-specific DNA binding F A1BG MCM6 GO:0009378 four-way junction helicase activity F A1BG MCM6 GO:0000166 nucleotide binding F A1BG MCM6 GO:0003688 DNA replication origin binding F A1BG MCM6 GO:0043142 single-stranded DNA-dependent ATPase activity F A1BG MCM6 GO:0003677 DNA binding F A1BG MCM6 GO:0003682 chromatin binding F A1BG MCM6 GO:0003697 A1BG MCM6 GO:0005524 ATP binding F CTDSPL SEY1 GO:0000166 nucleotide binding F CTDSPL SEY1 GO:0003924 GTPase activity F CTDSPL SEY1 GO:0005525 GTP binding F TMEM9 RAD14 GO:0000166 nucleotide binding F TMEM9 RAD14 GO:0003684 damaged DNA binding F TMEM9 RAD14 GO:0046872 metal ion binding F TMEM9 RAD14 GO:0008270 zinc ion binding F TMEM9 RAD14 GO:0003677 DNA binding F CHERP RPL37A GO:0003735 structural constituent of ribosome F CHERP RPL37A GO:0046872 metal ion binding F CHERP RPL37A GO:0008270 zinc ion binding F CHERP RPL37A GO:0003723 RNA binding F CHERP RPL37A GO:0019843 rRNA binding F SEC24C ACO1 GO:0051539 4 iron, 4 sulfur cluster binding F SEC24C ACO1 GO:0051536 iron-sulfur cluster binding F F SEC24C ACO1 GO:0003697 F SEC24C ACO1 GO:0005506 iron ion binding F SEC24C ACO1 GO:0003994 aconitate hydratase activity F SEC24C ACO1 GO:0003690 double-stranded DNA binding F SEC24C ACO1 GO:0046872 metal ion binding F SEC24C ACO1 GO:0016829 lyase activity F PDCD1LG2 YML081W GO:0043565 sequence-specific DNA binding F PDCD1LG2 YML081W GO:0046872 metal ion binding F PDCD1LG2 YML081W GO:0008270 zinc ion binding F PDCD1LG2 YML081W GO:0003676 nucleic acid binding F PDCD1LG2 YML081W GO:0003677 DNA binding F SART1 SYN8 GO:0005484 SNAP receptor activity F CXorf26 URA10 GO:0016740 transferase activity F CXorf26 URA10 GO:0016757 transferase activity, transferring glycosyl groups F CXorf26 URA10 GO:0004588 orotate phosphoribosyltransferase activity F PRB4 FAR1 GO:0004860 protein kinase inhibitor activity F PRB4 FAR1 GO:0004861 cyclin-dependent protein kinase inhibitor activity F PRB4 FAR1 GO:0046872 metal ion binding F PRB4 FAR1 GO:0008270 zinc ion binding F ING1 PUF4 GO:0003729 mRNA binding F ING1 PUF4 GO:0005488 binding F ING1 PUF4 GO:0003723 RNA binding F BSCL2 FMP41 GO:0003824 catalytic activity F BSCL2 FMP41 GO:0046872 metal ion binding F BSCL2 FMP41 GO:0016787 hydrolase activity F TIAF1 RSC1 GO:0003677 DNA binding F MAGEA12 AIM45 GO:0050660 FAD binding F MAGEA12 AIM45 GO:0009055 electron carrier activity F ETV3 CAF20 GO:0045182 translation regulator activity F ETV3 CAF20 GO:0003743 translation initiation factor activity F TAF7L TSC10 GO:0047560 3-dehydrosphinganine reductase activity F TAF7L TSC10 GO:0003824 catalytic activity F TAF7L TSC10 GO:0016491 oxidoreductase activity F TAF7L TSC10 GO:0016651 oxidoreductase activity, acting on NADH or NADPH F TAF7L TSC10 GO:0005488 binding F GNAS TAF5 GO:0016251 general RNA polymerase II transcription factor activity F GNAS TAF5 GO:0003682 chromatin binding F GNAS TAF5 GO:0003704 specific RNA polymerase II transcription factor activity F GNAS TAF5 GO:0030528 transcription regulator activity F PCID2 BDH1 GO:0005488 binding F PCID2 BDH1 GO:0000721 (R,R)-butanediol dehydrogenase activity F PCID2 BDH1 GO:0003824 catalytic activity F PCID2 BDH1 GO:0008270 zinc ion binding F PCID2 BDH1 GO:0046872 metal ion binding F PCID2 BDH1 GO:0016491 oxidoreductase activity F ALS2CR12 TFC6 GO:0003709 RNA polymerase III transcription factor activity F ALS2CR12 TFC6 GO:0003677 DNA binding F PPFIBP2 SAC6 GO:0003779 actin binding F PPFIBP2 SAC6 GO:0030674 protein binding, bridging F PPFIBP2 SAC6 GO:0005509 calcium ion binding F PPFIBP2 SAC6 GO:0051015 actin filament binding F SH3KBP1 TRA1 GO:0016773 phosphotransferase activity, alcohol group as acceptor F SH3KBP1 TRA1 GO:0016772 F SH3KBP1 TRA1 GO:0016301 transferase activity, transferring phosphorus-containing groups kinase activity SH3KBP1 TRA1 GO:0005488 binding F MLC1 TRR1 GO:0008198 ferrous iron binding F MLC1 TRR1 GO:0004791 thioredoxin-disulfide reductase activity F MLC1 TRR1 GO:0009055 electron carrier activity F MLC1 TRR1 GO:0050660 FAD binding F MLC1 TRR1 GO:0016491 oxidoreductase activity F GAS1 ATG1 GO:0016301 kinase activity F GAS1 ATG1 GO:0000166 nucleotide binding F GAS1 ATG1 GO:0004674 protein serine/threonine kinase activity F GAS1 ATG1 GO:0016740 transferase activity F GAS1 ATG1 GO:0004672 protein kinase activity F GAS1 ATG1 GO:0005524 ATP binding F TRIM6 CCT3 GO:0005524 ATP binding F TRIM6 CCT3 GO:0051082 unfolded protein binding F TRIM6 CCT3 GO:0000166 nucleotide binding F UBL5 BCY1 GO:0001932 regulation of protein amino acid phosphorylation P UBL5 BCY1 GO:0007568 aging P UBL5 BCY1 GO:0007039 vacuolar protein catabolic process P UBL5 BCY1 GO:0007165 signal transduction P UBL5 BCY1 GO:0019932 second-messenger-mediated signaling P UBL5 BCY1 GO:0007265 Ras protein signal transduction P UBL5 BCY1 GO:0007264 small GTPase mediated signal transduction P UBL5 BCY1 GO:0046580 negative regulation of Ras protein signal transduction P C9orf16 CMP2 GO:0000754 P C9orf16 CMP2 GO:0007039 adaptation to pheromone during conjugation with cellular fusion vacuolar protein catabolic process C9orf16 CMP2 GO:0006873 cellular ion homeostasis P SCGB2A2 MMT1 GO:0006812 cation transport P F P SCGB2A2 MMT1 GO:0006811 ion transport P SCGB2A2 MMT1 GO:0006810 transport P SCGB2A2 MMT1 GO:0006879 cellular iron ion homeostasis P SCGB2A2 MMT1 GO:0006826 iron ion transport P OCM TFC1 GO:0006350 transcription P OCM TFC1 GO:0006384 OCM TFC1 GO:0045449 regulation of transcription P NRSN2 PDR17 GO:0006869 lipid transport P NRSN2 PDR17 GO:0015914 phospholipid transport P NRSN2 PDR17 GO:0006810 transport P NRSN2 PDR17 GO:0042493 response to drug P NRSN2 PDR17 GO:0008654 phospholipid biosynthetic process P TRAP1 PRP39 GO:0016071 mRNA metabolic process P TRAP1 PRP39 GO:0000395 nuclear mRNA 5'-splice site recognition P TRAP1 PRP39 GO:0019953 sexual reproduction P TRAP1 PRP39 GO:0008380 RNA splicing P TRAP1 PRP39 GO:0006396 RNA processing P TRAP1 PRP39 GO:0006397 mRNA processing P MKRN1 GLC8 GO:0005978 glycogen biosynthetic process P MKRN1 GLC8 GO:0051098 regulation of binding P MKRN1 GLC8 GO:0044262 cellular carbohydrate metabolic process P MKRN1 GLC8 GO:0005977 glycogen metabolic process P MKRN1 GLC8 GO:0007059 chromosome segregation P PROL1 ATG2 GO:0030242 peroxisome degradation P PROL1 ATG2 GO:0006914 autophagy P PROL1 ATG2 GO:0006810 transport P PROL1 ATG2 GO:0000045 autophagic vacuole formation P PROL1 ATG2 GO:0015031 protein transport P PROL1 ATG2 GO:0032258 CVT pathway P PROL1 ATG2 GO:0034727 piecemeal microautophagy of nucleus P EXOSC8 MRPL20 GO:0032543 mitochondrial translation P IL25 GIM5 GO:0007021 tubulin complex assembly P IL25 GIM5 GO:0006461 protein complex assembly P IL25 GIM5 GO:0006457 protein folding P TLX2 DBP7 GO:0000027 ribosomal large subunit assembly P TLX2 DBP7 GO:0042254 ribosome biogenesis P TLX2 DBP7 GO:0006364 rRNA processing P FANCD2 CCL1 GO:0006350 transcription P FANCD2 CCL1 GO:0045449 regulation of transcription P FANCD2 CCL1 GO:0007049 cell cycle P FANCD2 CCL1 GO:0007070 negative regulation of transcription from RNA polymerase II promoter, mitotic P P FANCD2 CCL1 GO:0006367 P GO:0006984 transcription initiation from RNA polymerase II promoter ER-nuclear signaling pathway IFIT3 SCS2 IFIT3 SCS2 GO:0006348 chromatin silencing at telomere P IFIT3 SCS2 GO:0008654 phospholipid biosynthetic process P IFIT3 SCS2 GO:0048309 endoplasmic reticulum inheritance P IFIT3 SCS2 GO:0032377 regulation of intracellular lipid transport P IFIT3 SCS2 GO:0042992 P IFIT2 HSK3 GO:0031110 IFIT2 HSK3 GO:0030472 negative regulation of transcription factor import into nucleus regulation of microtubule polymerization or depolymerization mitotic spindle organization in nucleus IFIT2 HSK3 GO:0051301 cell division P IFIT2 HSK3 GO:0007059 chromosome segregation P IFIT2 HSK3 GO:0007067 mitosis P IFIT2 HSK3 GO:0007049 cell cycle P IFIT1 OSH2 GO:0006887 exocytosis P IFIT1 OSH2 GO:0006897 endocytosis P IFIT1 OSH2 GO:0015918 sterol transport P IFIT1 OSH2 GO:0006869 lipid transport P IFIT1 OSH2 GO:0006810 transport P IFIT1 OSH2 GO:0030011 maintenance of cell polarity P IFIT1 OSH2 GO:0008202 steroid metabolic process P CHIC2 RPC82 GO:0006350 transcription P CHIC2 RPC82 GO:0006383 transcription from RNA polymerase III promoter P LOXL3 LGE1 GO:0006279 premeiotic DNA synthesis P LOXL3 LGE1 GO:0006350 transcription P LOXL3 LGE1 GO:0006513 protein monoubiquitination P LOXL3 LGE1 GO:0016574 histone ubiquitination P LOXL3 LGE1 GO:0030435 sporulation resulting in formation of a cellular spore P LOXL3 LGE1 GO:0008361 regulation of cell size P LOXL3 LGE1 GO:0045449 regulation of transcription P LOXL3 LGE1 GO:0016571 histone methylation P LOXL3 LGE1 GO:0016568 chromatin modification P RBM8A AIR2 GO:0071031 RBM8A AIR2 GO:0016073 RBM8A AIR2 GO:0071037 P RBM8A AIR2 GO:0071036 P RBM8A AIR2 GO:0071035 P RBM8A AIR2 GO:0071039 P RBM8A AIR2 GO:0071038 P RBM8A AIR2 GO:0043629 P P P P snRNA metabolic process ncRNA polyadenylation P P B3GNT2 SUM1 GO:0030466 chromatin silencing at silent mating-type cassette P B3GNT2 SUM1 GO:0006348 chromatin silencing at telomere P B3GNT2 SUM1 GO:0006270 DNA replication initiation P B3GNT2 SUM1 GO:0030435 sporulation resulting in formation of a cellular spore P B3GNT2 SUM1 GO:0045449 regulation of transcription P B3GNT2 SUM1 GO:0006350 transcription P B3GNT2 SUM1 GO:0007088 regulation of mitosis P B3GNT2 SUM1 GO:0016481 negative regulation of transcription P JMJD5 UBA2 GO:0016925 protein sumoylation P JMJD5 UBA2 GO:0019941 modification-dependent protein catabolic process P JMJD5 UBA2 GO:0006464 protein modification process P JMJD5 UBA2 GO:0008152 metabolic process P C10orf119 ERG1 GO:0019748 secondary metabolic process P C10orf119 ERG1 GO:0008152 metabolic process P C10orf119 ERG1 GO:0055114 oxidation reduction P C10orf119 ERG1 GO:0006696 ergosterol biosynthetic process P RETN YBP1 GO:0006979 response to oxidative stress P P2RY13 ATM1 GO:0006826 iron ion transport P P2RY13 ATM1 GO:0006811 ion transport P P2RY13 ATM1 GO:0006810 transport P P2RY13 ATM1 GO:0006879 cellular iron ion homeostasis P FOXRED1 YDR061W GO:0006810 transport P WSB1 INO80 GO:0006348 chromatin silencing at telomere P WSB1 INO80 GO:0006338 chromatin remodeling P WSB1 INO80 GO:0006281 DNA repair P WSB1 INO80 GO:0006366 transcription from RNA polymerase II promoter P WSB1 INO80 GO:0043618 P WSB1 INO80 GO:0006974 regulation of transcription from RNA polymerase II promoter in response to stress response to DNA damage stimulus WSB1 INO80 GO:0006350 transcription P WSB1 INO80 GO:0010552 P WSB1 INO80 GO:0045449 positive regulation of specific transcription from RNA polymerase II promoter regulation of transcription WSB1 INO80 GO:0042766 nucleosome mobilization P WSB1 INO80 GO:0016568 chromatin modification P PGM5 MLC2 GO:0051301 cell division P PGM5 MLC2 GO:0000003 reproduction P PGM5 MLC2 GO:0007049 cell cycle P PGM5 MLC2 GO:0000916 contractile ring contraction involved in cytokinesis P OFD1 CSR1 GO:0009395 phospholipid catabolic process P OFD1 CSR1 GO:0019217 regulation of fatty acid metabolic process P OFD1 CSR1 GO:0006869 lipid transport P P P OFD1 CSR1 GO:0015914 phospholipid transport P OFD1 CSR1 GO:0006810 transport P OFD1 CSR1 GO:0007047 cell wall organization P OFD1 CSR1 GO:0030433 ER-associated protein catabolic process P OFD1 CSR1 GO:0044255 cellular lipid metabolic process P SURF2 DRE2 GO:0010421 hydrogen peroxide-mediated programmed cell death P SURF2 DRE2 GO:0007064 mitotic sister chromatid cohesion P SURF2 DRE2 GO:0016226 iron-sulfur cluster assembly P A1BG MCM6 GO:0006350 transcription P A1BG MCM6 GO:0006342 chromatin silencing P A1BG MCM6 GO:0000084 S phase of mitotic cell cycle P A1BG MCM6 GO:0006270 DNA replication initiation P A1BG MCM6 GO:0040029 regulation of gene expression, epigenetic P A1BG MCM6 GO:0006267 pre-replicative complex assembly P A1BG MCM6 GO:0045449 regulation of transcription P A1BG MCM6 GO:0051049 regulation of transport P A1BG MCM6 GO:0006260 DNA replication P A1BG MCM6 GO:0045814 negative regulation of gene expression, epigenetic P A1BG MCM6 GO:0006268 DNA unwinding during replication P A1BG MCM6 GO:0006271 DNA strand elongation during DNA replication P A1BG MCM6 GO:0007049 cell cycle P CTDSPL SEY1 GO:0007029 endoplasmic reticulum organization P CTDSPL SEY1 GO:0016044 membrane organization P CTDSPL SEY1 GO:0006950 response to stress P SCGN ZEO1 GO:0007047 cell wall organization P SCGN ZEO1 GO:0006950 response to stress P NR4A3 UMP1 GO:0006974 response to DNA damage stimulus P NR4A3 UMP1 GO:0006508 proteolysis P NR4A3 UMP1 GO:0006511 ubiquitin-dependent protein catabolic process P NR4A3 UMP1 GO:0043248 proteasome assembly P BZRAP1 MET6 GO:0008652 cellular amino acid biosynthetic process P BZRAP1 MET6 GO:0009086 methionine biosynthetic process P BZRAP1 MET6 GO:0006519 cellular amino acid and derivative metabolic process P BZRAP1 MET6 GO:0006807 nitrogen compound metabolic process P BZRAP1 MET6 GO:0006790 sulfur metabolic process P BZRAP1 MET6 GO:0006414 translational elongation P BZRAP1 MET6 GO:0046483 heterocycle metabolic process P OASL RPL15B GO:0006412 translation P MUC4 PAM1 GO:0007124 pseudohyphal growth P MUC4 PAM1 GO:0009966 regulation of signal transduction P MUC4 PAM1 GO:0000003 reproduction P MUC4 PAM1 GO:0051301 cell division P TMEM9 RAD14 GO:0006974 response to DNA damage stimulus P TMEM9 RAD14 GO:0006914 autophagy P TMEM9 RAD14 GO:0006281 DNA repair P TMEM9 RAD14 GO:0000715 nucleotide-excision repair, DNA damage recognition P TMEM9 RAD14 GO:0006289 nucleotide-excision repair P CHERP RPL37A GO:0006412 translation P TPD52L1 CDC3 GO:0000910 cytokinesis P TPD52L1 CDC3 GO:0000747 conjugation with cellular fusion P TPD52L1 CDC3 GO:0000746 conjugation P TPD52L1 CDC3 GO:0007120 axial cellular bud site selection P TPD52L1 CDC3 GO:0000902 cell morphogenesis P TPD52L1 CDC3 GO:0051049 regulation of transport P TPD52L1 CDC3 GO:0007047 cell wall organization P TPD52L1 CDC3 GO:0007049 cell cycle P TPD52L1 CDC3 GO:0030010 establishment of cell polarity P TPD52L1 CDC3 GO:0051301 cell division P TPD52L1 CDC3 GO:0051704 multi-organism process P CXorf26 URA10 GO:0006207 'de novo' pyrimidine base biosynthetic process P CXorf26 URA10 GO:0009116 nucleoside metabolic process P CXorf26 URA10 GO:0046132 pyrimidine ribonucleoside biosynthetic process P CXorf26 URA10 GO:0006221 pyrimidine nucleotide biosynthetic process P PRB4 FAR1 GO:0000746 conjugation P PRB4 FAR1 GO:0000750 P PRB4 FAR1 GO:0000751 pheromone-dependent signal transduction involved in conjugation with cellular fusion cell cycle arrest in response to pheromone PRB4 FAR1 GO:0030447 filamentous growth P PRB4 FAR1 GO:0050790 regulation of catalytic activity P PRB4 FAR1 GO:0019953 sexual reproduction P PRB4 FAR1 GO:0007049 cell cycle P PRB4 FAR1 GO:0007166 cell surface receptor linked signal transduction P PRB4 FAR1 GO:0019236 response to pheromone P PRB4 FAR1 GO:0051301 cell division P NPFFR1 RAD51 GO:0000709 meiotic joint molecule formation P NPFFR1 RAD51 GO:0000722 telomere maintenance via recombination P NPFFR1 RAD51 GO:0051321 meiotic cell cycle P NPFFR1 RAD51 GO:0000725 recombinational repair P NPFFR1 RAD51 GO:0006281 DNA repair P NPFFR1 RAD51 GO:0030491 heteroduplex formation P NPFFR1 RAD51 GO:0006974 response to DNA damage stimulus P NPFFR1 RAD51 GO:0000724 double-strand break repair via homologous recombination P P NPFFR1 RAD51 GO:0006310 DNA recombination P NPFFR1 RAD51 GO:0006259 DNA metabolic process P NPFFR1 RAD51 GO:0042148 strand invasion P NPFFR1 RAD51 GO:0007131 reciprocal meiotic recombination P BSCL2 FMP41 GO:0006950 response to stress P BSCL2 FMP41 GO:0008152 metabolic process P MAGEA12 AIM45 GO:0022900 electron transport chain P MAGEA12 AIM45 GO:0006810 transport P ETV3 CAF20 GO:0006417 regulation of translation P ETV3 CAF20 GO:0010606 P ETV3 CAF20 GO:0006412 positive regulation of cytoplasmic mRNA processing body assembly translation ETV3 CAF20 GO:0017148 negative regulation of translation P TAF7L TSC10 GO:0030148 sphingolipid biosynthetic process P TAF7L TSC10 GO:0006666 3-keto-sphinganine metabolic process P TAF7L TSC10 GO:0008152 metabolic process P TAF7L TSC10 GO:0055114 oxidation reduction P TAF7L TSC10 GO:0018193 peptidyl-amino acid modification P LRP4 TAH18 GO:0010421 hydrogen peroxide-mediated programmed cell death P LRP4 TAH18 GO:0031329 regulation of cellular catabolic process P LRP4 TAH18 GO:0055114 oxidation reduction P PRCC YLR132C GO:0008380 RNA splicing P PRCC YLR132C GO:0006397 mRNA processing P PCID2 BDH1 GO:0006066 alcohol metabolic process P PCID2 BDH1 GO:0034605 cellular response to heat P PCID2 BDH1 GO:0008152 metabolic process P PCID2 BDH1 GO:0055114 oxidation reduction P CSHL1 HAM1 GO:0006974 response to DNA damage stimulus P CSHL1 HAM1 GO:0043094 cellular metabolic compound salvage P CSHL1 HAM1 GO:0009204 deoxyribonucleoside triphosphate catabolic process P CSHL1 HAM1 GO:0018193 peptidyl-amino acid modification P RBMX SMD2 GO:0016071 mRNA metabolic process P RBMX SMD2 GO:0008380 RNA splicing P RBMX SMD2 GO:0000398 nuclear mRNA splicing, via spliceosome P RBMX SMD2 GO:0006397 mRNA processing P SCGB2A1 TRR2 GO:0019430 removal of superoxide radicals P SCGB2A1 TRR2 GO:0045454 cell redox homeostasis P SCGB2A1 TRR2 GO:0006979 response to oxidative stress P SCGB2A1 TRR2 GO:0055114 oxidation reduction P SCGB2A1 TRR2 GO:0051049 regulation of transport P MLC1 TRR1 GO:0019430 removal of superoxide radicals P MLC1 TRR1 GO:0045454 cell redox homeostasis P P MLC1 TRR1 GO:0006979 response to oxidative stress P MLC1 TRR1 GO:0055114 oxidation reduction P TRIM2 SEC66 GO:0015031 protein transport P TRIM2 SEC66 GO:0031204 P TRIM2 SEC66 GO:0030447 posttranslational protein targeting to membrane, translocation filamentous growth TRIM2 SEC66 GO:0006810 transport P P