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Supplementary Table 1: Predictions for human proteins based on the complete GO annotation data set. The column denoted
by “Protein (H)” contains a human protein for which we predict a GO term. The column denoted by “Protein (Y)” contains a
yeast protein that is aligned to the corresponding human protein and that is annotated with the GO term that we assign to
the human protein. The predicted GO term is given in the column denoted by “GO term accession.” Its name and ontology
(i.e., molecular function (F), biological process (P), or cellular component (C)) are given in the columns denoted by “GO
name” and “GO ontology,” respectively.
Protein(H)
Protein(Y) GO term
accession
GO name
Go
ontology
C9orf16
CMP2
GO:0005737
cytoplasm
C
C9orf16
CMP2
GO:0005955
calcineurin complex
C
OCM
TFC1
GO:0000127
transcription factor TFIIIC complex
C
OCM
TFC1
GO:0005634
nucleus
C
TRAP1
PRP39
GO:0005634
nucleus
C
TRAP1
PRP39
GO:0000243
commitment complex
C
TRAP1
PRP39
GO:0005685
snRNP U1
C
TRAP1
PRP39
GO:0005622
intracellular
C
MKRN1
GLC8
GO:0005737
cytoplasm
C
MKRN1
GLC8
GO:0005634
nucleus
C
EXOSC8
MRPL20
GO:0005840
ribosome
C
EXOSC8
MRPL20
GO:0005739
mitochondrion
C
EXOSC8
MRPL20
GO:0005762
mitochondrial large ribosomal subunit
C
EXOSC8
MRPL20
GO:0030529
ribonucleoprotein complex
C
TLX2
DBP7
GO:0005634
nucleus
C
TLX2
DBP7
GO:0005730
nucleolus
C
FANCD2
CCL1
GO:0000109
nucleotide-excision repair complex
C
FANCD2
CCL1
GO:0005739
mitochondrion
C
FANCD2
CCL1
GO:0005675
holo TFIIH complex
C
ARID4B
YLL023C
GO:0016021
integral to membrane
C
ARID4B
YLL023C
GO:0016020
membrane
C
ARID4B
YLL023C
GO:0005783
endoplasmic reticulum
C
6-Sep
ORC2
GO:0005634
nucleus
C
6-Sep
ORC2
GO:0005664
nuclear origin of replication recognition complex
C
6-Sep
ORC2
GO:0005656
pre-replicative complex
C
6-Sep
ORC2
GO:0000808
origin recognition complex
C
6-Sep
ORC2
GO:0031261
DNA replication preinitiation complex
C
IFIT3
SCS2
GO:0005635
nuclear envelope
C
IFIT3
SCS2
GO:0005783
endoplasmic reticulum
C
IFIT3
SCS2
GO:0005634
nucleus
C
IFIT3
SCS2
GO:0016020
membrane
C
IFIT3
SCS2
GO:0031965
nuclear membrane
C
IFIT3
SCS2
GO:0030176
integral to endoplasmic reticulum membrane
C
IFIT3
SCS2
GO:0005934
cellular bud tip
C
IFIT3
SCS2
GO:0016021
integral to membrane
C
IFIT2
HSK3
GO:0005819
spindle
C
IFIT2
HSK3
GO:0042729
IFIT2
HSK3
GO:0005634
nucleus
C
IFIT2
HSK3
GO:0005874
microtubule
C
IFIT2
HSK3
GO:0000776
kinetochore
C
IFIT2
HSK3
GO:0000777
condensed chromosome kinetochore
C
USP21
NNF2
GO:0005624
membrane fraction
C
USP21
NNF2
GO:0016021
integral to membrane
C
USP21
NNF2
GO:0016020
membrane
C
USP21
NNF2
GO:0005783
endoplasmic reticulum
C
USP20
YRB30
GO:0005737
cytoplasm
C
USP20
YRB30
GO:0005634
nucleus
C
CHIC2
RPC82
GO:0005737
cytoplasm
C
CHIC2
RPC82
GO:0005634
nucleus
C
CHIC2
RPC82
GO:0005666
DNA-directed RNA polymerase III complex
C
MAP3K9
ZPR1
GO:0005737
cytoplasm
C
MAP3K9
ZPR1
GO:0005634
nucleus
C
JMJD5
UBA2
GO:0005634
nucleus
C
JMJD5
UBA2
GO:0031510
SUMO activating enzyme complex
C
C10orf119
ERG1
GO:0016021
integral to membrane
C
C10orf119
ERG1
GO:0016020
membrane
C
C10orf119
ERG1
GO:0005811
lipid particle
C
C10orf119
ERG1
GO:0005792
microsome
C
C10orf119
ERG1
GO:0005783
endoplasmic reticulum
C
RGS6
HOS4
GO:0034967
Set3 complex
C
ODC1
CMK2
GO:0005737
cytoplasm
C
MAPK3
DBP9
GO:0005634
nucleus
C
MAPK3
DBP9
GO:0005730
nucleolus
C
FOXRED1
YDR061W
GO:0005739
mitochondrion
C
WSB1
INO80
GO:0005634
nucleus
C
WSB1
INO80
GO:0031011
Ino80 complex
C
NME5
PCL7
GO:0005737
cytoplasm
C
NME5
PCL7
GO:0000307
cyclin-dependent protein kinase holoenzyme complex
C
NME5
PCL7
GO:0005634
nucleus
C
OFD1
CSR1
GO:0005737
cytoplasm
C
OFD1
CSR1
GO:0005792
microsome
C
OFD1
CSR1
GO:0005829
cytosol
C
OFD1
CSR1
GO:0005811
lipid particle
C
OFD1
CSR1
GO:0005739
mitochondrion
C
OFD1
CSR1
GO:0005768
endosome
C
SURF2
DRE2
GO:0005737
cytoplasm
C
C
SURF2
DRE2
GO:0005758
mitochondrial intermembrane space
C
SURF2
DRE2
GO:0005829
cytosol
C
PHKG2
ARC15
GO:0005737
cytoplasm
C
PHKG2
ARC15
GO:0005856
cytoskeleton
C
PHKG2
ARC15
GO:0030479
actin cortical patch
C
PHKG2
ARC15
GO:0031315
extrinsic to mitochondrial outer membrane
C
PHKG2
ARC15
GO:0005885
Arp2/3 protein complex
C
PHKG2
ARC15
GO:0005938
cell cortex
C
PHKG2
ARC15
GO:0044448
cell cortex part
C
BCL7A
YER077C
GO:0005739
mitochondrion
C
CTDSPL
SEY1
GO:0005737
cytoplasm
C
CTDSPL
SEY1
GO:0016021
integral to membrane
C
CTDSPL
SEY1
GO:0016020
membrane
C
CTDSPL
SEY1
GO:0005783
endoplasmic reticulum
C
CTDSPL
SEY1
GO:0032541
cortical endoplasmic reticulum
C
NKIRAS2
URH1
GO:0005737
cytoplasm
C
NKIRAS2
URH1
GO:0005634
nucleus
C
MTM1
YER140W
GO:0016021
integral to membrane
C
MTM1
YER140W
GO:0016020
membrane
C
MTM1
YER140W
GO:0005739
mitochondrion
C
PCYT2
SDH1
GO:0005743
mitochondrial inner membrane
C
PCYT2
SDH1
GO:0016020
membrane
C
PCYT2
SDH1
GO:0005749
mitochondrial respiratory chain complex II
C
PCYT2
SDH1
GO:0005739
mitochondrion
C
PCYT2
SDH1
GO:0031966
mitochondrial membrane
C
LTB
TRX2
GO:0005737
cytoplasm
C
LTB
TRX2
GO:0005794
Golgi apparatus
C
LTB
TRX2
GO:0000324
fungal-type vacuole
C
LTB
TRX2
GO:0005634
nucleus
C
LTB
TRX2
GO:0016020
membrane
C
LTB
TRX2
GO:0005829
cytosol
C
ZFAND5
YMR310C
GO:0005634
nucleus
C
TAF1L
SQT1
GO:0005737
cytoplasm
C
TAF1L
SQT1
GO:0005829
cytosol
C
TAF1L
SQT1
GO:0022626
cytosolic ribosome
C
CHERP
RPL37A
GO:0005737
cytoplasm
C
CHERP
RPL37A
GO:0030529
ribonucleoprotein complex
C
CHERP
RPL37A
GO:0005840
ribosome
C
CHERP
RPL37A
GO:0005622
intracellular
C
CHERP
RPL37A
GO:0022625
cytosolic large ribosomal subunit
C
TPD52L1
CDC3
GO:0031105
septin complex
C
TPD52L1
CDC3
GO:0005628
prospore membrane
C
TPD52L1
CDC3
GO:0000144
cellular bud neck septin ring
C
TPD52L1
CDC3
GO:0001400
mating projection base
C
TPD52L1
CDC3
GO:0016020
membrane
C
TPD52L1
CDC3
GO:0005619
ascospore wall
C
TPD52L1
CDC3
GO:0005935
GALNT5
NIF3
GO:0005737
cytoplasm
C
GALNT5
NIF3
GO:0005739
mitochondrion
C
CXorf26
URA10
GO:0005737
cytoplasm
C
ASMTL
RNH202
GO:0005634
nucleus
C
ASMTL
RNH202
GO:0032299
ribonuclease H2 complex
C
MAGEA12
AIM45
GO:0005759
mitochondrial matrix
C
MAGEA12
AIM45
GO:0005739
mitochondrion
C
LRP4
TAH18
GO:0005739
mitochondrion
C
DDX24
RPL11B
GO:0005737
cytoplasm
C
DDX24
RPL11B
GO:0030529
ribonucleoprotein complex
C
DDX24
RPL11B
GO:0005840
ribosome
C
DDX24
RPL11B
GO:0005622
intracellular
C
DDX24
RPL11B
GO:0022625
cytosolic large ribosomal subunit
C
CCND1
RPL12B
GO:0005737
cytoplasm
C
CCND1
RPL12B
GO:0030529
ribonucleoprotein complex
C
CCND1
RPL12B
GO:0005840
ribosome
C
CCND1
RPL12B
GO:0005622
intracellular
C
CCND1
RPL12B
GO:0022625
cytosolic large ribosomal subunit
C
PCID2
BDH1
GO:0005737
cytoplasm
C
ALS2CR12
TFC6
GO:0000127
transcription factor TFIIIC complex
C
ALS2CR12
TFC6
GO:0005634
nucleus
C
PLCG1
RPS9B
GO:0005737
cytoplasm
C
PLCG1
RPS9B
GO:0032040
small-subunit processome
C
PLCG1
RPS9B
GO:0015935
small ribosomal subunit
C
PLCG1
RPS9B
GO:0005730
nucleolus
C
PLCG1
RPS9B
GO:0005634
nucleus
C
PLCG1
RPS9B
GO:0030686
90S preribosome
C
PLCG1
RPS9B
GO:0005622
intracellular
C
PLCG1
RPS9B
GO:0005840
ribosome
C
PLCG1
RPS9B
GO:0030529
ribonucleoprotein complex
C
PLCG1
RPS9B
GO:0022627
cytosolic small ribosomal subunit
C
PRX
IMH1
GO:0005737
cytoplasm
C
PRX
IMH1
GO:0005794
Golgi apparatus
C
PRX
IMH1
GO:0005829
cytosol
C
PRX
IMH1
GO:0016020
membrane
C
C
PRCC
YLR132C
GO:0005737
cytoplasm
C
PRCC
YLR132C
GO:0005634
nucleus
C
PRCC
YLR132C
GO:0005739
mitochondrion
C
MTPN
GND1
GO:0005737
cytoplasm
C
MTPN
GND1
GO:0005739
mitochondrion
C
CUL4B
PIH1
GO:0005737
cytoplasm
C
CUL4B
PIH1
GO:0005634
nucleus
C
CUL4B
PIH1
GO:0005732
small nucleolar ribonucleoprotein complex
C
DDX1
MRPS9
GO:0030529
ribonucleoprotein complex
C
DDX1
MRPS9
GO:0005622
intracellular
C
DDX1
MRPS9
GO:0005840
ribosome
C
DDX1
MRPS9
GO:0005739
mitochondrion
C
DDX1
MRPS9
GO:0005763
mitochondrial small ribosomal subunit
C
PSKH1
RNT1
GO:0005654
nucleoplasm
C
PSKH1
RNT1
GO:0005622
intracellular
C
PSKH1
RNT1
GO:0005730
nucleolus
C
UBL5
BCY1
GO:0030552
cAMP binding
F
UBL5
BCY1
GO:0008603
cAMP-dependent protein kinase regulator activity
F
UBL5
BCY1
GO:0000166
nucleotide binding
F
UBL5
BCY1
GO:0004862
cAMP-dependent protein kinase inhibitor activity
F
UBL5
BCY1
GO:0004691
cAMP-dependent protein kinase activity
F
UBL5
BCY1
GO:0004690
cyclic nucleotide-dependent protein kinase activity
F
C9orf16
CMP2
GO:0016787
hydrolase activity
F
C9orf16
CMP2
GO:0004721
phosphoprotein phosphatase activity
F
C9orf16
CMP2
GO:0005516
calmodulin binding
F
C9orf16
CMP2
GO:0005506
iron ion binding
F
C9orf16
CMP2
GO:0046872
metal ion binding
F
C9orf16
CMP2
GO:0008270
zinc ion binding
F
MFRP
TFS1
GO:0005543
phospholipid binding
F
MFRP
TFS1
GO:0008289
lipid binding
F
MFRP
TFS1
GO:0030414
peptidase inhibitor activity
F
MFRP
TFS1
GO:0004867
serine-type endopeptidase inhibitor activity
F
NRSN2
PDR17
GO:0008526
phosphatidylinositol transporter activity
F
MKRN1
GLC8
GO:0008047
enzyme activator activity
F
EXOSC8
MRPL20
GO:0003735
structural constituent of ribosome
F
MFAP4
DAM1
GO:0005200
structural constituent of cytoskeleton
F
DLK1
VMA4
GO:0015078
hydrogen ion transmembrane transporter activity
F
DLK1
VMA4
GO:0046961
F
NPTX2
ATP16
GO:0016787
proton-transporting ATPase activity, rotational
mechanism
hydrolase activity
NPTX2
ATP16
GO:0015078
hydrogen ion transmembrane transporter activity
F
NPTX2
ATP16
GO:0046961
proton-transporting ATPase activity, rotational
F
F
mechanism
NPTX2
ATP16
GO:0046933
F
GO:0016251
hydrogen ion transporting ATP synthase activity,
rotational mechanism
general RNA polymerase II transcription factor activity
FANCD2
CCL1
FANCD2
CCL1
GO:0016538
cyclin-dependent protein kinase regulator activity
F
KREMEN1
DBP6
GO:0016787
hydrolase activity
F
KREMEN1
DBP6
GO:0008026
ATP-dependent helicase activity
F
KREMEN1
DBP6
GO:0004004
ATP-dependent RNA helicase activity
F
KREMEN1
DBP6
GO:0004386
helicase activity
F
KREMEN1
DBP6
GO:0003723
RNA binding
F
KREMEN1
DBP6
GO:0003676
nucleic acid binding
F
KREMEN1
DBP6
GO:0000166
nucleotide binding
F
KREMEN1
DBP6
GO:0005524
ATP binding
F
CHIC2
RPC82
GO:0003899
DNA-directed RNA polymerase activity
F
CHIC2
RPC82
GO:0008270
zinc ion binding
F
CHIC2
RPC82
GO:0003677
DNA binding
F
JMJD5
UBA2
GO:0019948
SUMO activating enzyme activity
F
JMJD5
UBA2
GO:0008641
small protein activating enzyme activity
F
JMJD5
UBA2
GO:0000166
nucleotide binding
F
JMJD5
UBA2
GO:0003824
catalytic activity
F
JMJD5
UBA2
GO:0005488
binding
F
JMJD5
UBA2
GO:0016874
ligase activity
F
JMJD5
UBA2
GO:0005524
ATP binding
F
C10orf119
ERG1
GO:0008144
drug binding
F
C10orf119
ERG1
GO:0004506
squalene monooxygenase activity
F
C10orf119
ERG1
GO:0050660
FAD binding
F
C10orf119
ERG1
GO:0016491
oxidoreductase activity
F
NEFH
ORC4
GO:0003688
DNA replication origin binding
F
NEFH
ORC4
GO:0003677
DNA binding
F
FOXRED1
YDR061W
GO:0000166
nucleotide binding
F
FOXRED1
YDR061W
GO:0017111
nucleoside-triphosphatase activity
F
FOXRED1
YDR061W
GO:0016887
ATPase activity
F
FOXRED1
YDR061W
GO:0005524
ATP binding
F
WSB1
INO80
GO:0016787
hydrolase activity
F
WSB1
INO80
GO:0016887
ATPase activity
F
WSB1
INO80
GO:0000166
nucleotide binding
F
WSB1
INO80
GO:0003676
nucleic acid binding
F
WSB1
INO80
GO:0003677
DNA binding
F
WSB1
INO80
GO:0004386
helicase activity
F
WSB1
INO80
GO:0005524
ATP binding
F
CRISP3
MCM5
GO:0009378
four-way junction helicase activity
F
CRISP3
MCM5
GO:0042623
ATPase activity, coupled
F
F
CRISP3
MCM5
GO:0004003
ATP-dependent DNA helicase activity
F
CRISP3
MCM5
GO:0003682
chromatin binding
F
CRISP3
MCM5
GO:0017111
nucleoside-triphosphatase activity
F
CRISP3
MCM5
GO:0000166
nucleotide binding
F
CRISP3
MCM5
GO:0003688
DNA replication origin binding
F
CRISP3
MCM5
GO:0016887
ATPase activity
F
CRISP3
MCM5
GO:0003677
DNA binding
F
CRISP3
MCM5
GO:0043138
3'-5' DNA helicase activity
F
CRISP3
MCM5
GO:0005524
ATP binding
F
OFD1
CSR1
GO:0008526
phosphatidylinositol transporter activity
F
LFNG
KKQ8
GO:0016301
kinase activity
F
LFNG
KKQ8
GO:0000166
nucleotide binding
F
LFNG
KKQ8
GO:0004674
protein serine/threonine kinase activity
F
LFNG
KKQ8
GO:0016740
transferase activity
F
LFNG
KKQ8
GO:0004672
protein kinase activity
F
LFNG
KKQ8
GO:0005524
ATP binding
F
MORF4L2
MRP21
GO:0003735
structural constituent of ribosome
F
A1BG
MCM6
GO:0043566
structure-specific DNA binding
F
A1BG
MCM6
GO:0009378
four-way junction helicase activity
F
A1BG
MCM6
GO:0000166
nucleotide binding
F
A1BG
MCM6
GO:0003688
DNA replication origin binding
F
A1BG
MCM6
GO:0043142
single-stranded DNA-dependent ATPase activity
F
A1BG
MCM6
GO:0003677
DNA binding
F
A1BG
MCM6
GO:0003682
chromatin binding
F
A1BG
MCM6
GO:0003697
A1BG
MCM6
GO:0005524
ATP binding
F
CTDSPL
SEY1
GO:0000166
nucleotide binding
F
CTDSPL
SEY1
GO:0003924
GTPase activity
F
CTDSPL
SEY1
GO:0005525
GTP binding
F
TMEM9
RAD14
GO:0000166
nucleotide binding
F
TMEM9
RAD14
GO:0003684
damaged DNA binding
F
TMEM9
RAD14
GO:0046872
metal ion binding
F
TMEM9
RAD14
GO:0008270
zinc ion binding
F
TMEM9
RAD14
GO:0003677
DNA binding
F
CHERP
RPL37A
GO:0003735
structural constituent of ribosome
F
CHERP
RPL37A
GO:0046872
metal ion binding
F
CHERP
RPL37A
GO:0008270
zinc ion binding
F
CHERP
RPL37A
GO:0003723
RNA binding
F
CHERP
RPL37A
GO:0019843
rRNA binding
F
SEC24C
ACO1
GO:0051539
4 iron, 4 sulfur cluster binding
F
SEC24C
ACO1
GO:0051536
iron-sulfur cluster binding
F
F
SEC24C
ACO1
GO:0003697
F
SEC24C
ACO1
GO:0005506
iron ion binding
F
SEC24C
ACO1
GO:0003994
aconitate hydratase activity
F
SEC24C
ACO1
GO:0003690
double-stranded DNA binding
F
SEC24C
ACO1
GO:0046872
metal ion binding
F
SEC24C
ACO1
GO:0016829
lyase activity
F
PDCD1LG2
YML081W
GO:0043565
sequence-specific DNA binding
F
PDCD1LG2
YML081W
GO:0046872
metal ion binding
F
PDCD1LG2
YML081W
GO:0008270
zinc ion binding
F
PDCD1LG2
YML081W
GO:0003676
nucleic acid binding
F
PDCD1LG2
YML081W
GO:0003677
DNA binding
F
SART1
SYN8
GO:0005484
SNAP receptor activity
F
CXorf26
URA10
GO:0016740
transferase activity
F
CXorf26
URA10
GO:0016757
transferase activity, transferring glycosyl groups
F
CXorf26
URA10
GO:0004588
orotate phosphoribosyltransferase activity
F
PRB4
FAR1
GO:0004860
protein kinase inhibitor activity
F
PRB4
FAR1
GO:0004861
cyclin-dependent protein kinase inhibitor activity
F
PRB4
FAR1
GO:0046872
metal ion binding
F
PRB4
FAR1
GO:0008270
zinc ion binding
F
ING1
PUF4
GO:0003729
mRNA binding
F
ING1
PUF4
GO:0005488
binding
F
ING1
PUF4
GO:0003723
RNA binding
F
BSCL2
FMP41
GO:0003824
catalytic activity
F
BSCL2
FMP41
GO:0046872
metal ion binding
F
BSCL2
FMP41
GO:0016787
hydrolase activity
F
TIAF1
RSC1
GO:0003677
DNA binding
F
MAGEA12
AIM45
GO:0050660
FAD binding
F
MAGEA12
AIM45
GO:0009055
electron carrier activity
F
ETV3
CAF20
GO:0045182
translation regulator activity
F
ETV3
CAF20
GO:0003743
translation initiation factor activity
F
TAF7L
TSC10
GO:0047560
3-dehydrosphinganine reductase activity
F
TAF7L
TSC10
GO:0003824
catalytic activity
F
TAF7L
TSC10
GO:0016491
oxidoreductase activity
F
TAF7L
TSC10
GO:0016651
oxidoreductase activity, acting on NADH or NADPH
F
TAF7L
TSC10
GO:0005488
binding
F
GNAS
TAF5
GO:0016251
general RNA polymerase II transcription factor activity
F
GNAS
TAF5
GO:0003682
chromatin binding
F
GNAS
TAF5
GO:0003704
specific RNA polymerase II transcription factor activity
F
GNAS
TAF5
GO:0030528
transcription regulator activity
F
PCID2
BDH1
GO:0005488
binding
F
PCID2
BDH1
GO:0000721
(R,R)-butanediol dehydrogenase activity
F
PCID2
BDH1
GO:0003824
catalytic activity
F
PCID2
BDH1
GO:0008270
zinc ion binding
F
PCID2
BDH1
GO:0046872
metal ion binding
F
PCID2
BDH1
GO:0016491
oxidoreductase activity
F
ALS2CR12
TFC6
GO:0003709
RNA polymerase III transcription factor activity
F
ALS2CR12
TFC6
GO:0003677
DNA binding
F
PPFIBP2
SAC6
GO:0003779
actin binding
F
PPFIBP2
SAC6
GO:0030674
protein binding, bridging
F
PPFIBP2
SAC6
GO:0005509
calcium ion binding
F
PPFIBP2
SAC6
GO:0051015
actin filament binding
F
SH3KBP1
TRA1
GO:0016773
phosphotransferase activity, alcohol group as acceptor
F
SH3KBP1
TRA1
GO:0016772
F
SH3KBP1
TRA1
GO:0016301
transferase activity, transferring phosphorus-containing
groups
kinase activity
SH3KBP1
TRA1
GO:0005488
binding
F
MLC1
TRR1
GO:0008198
ferrous iron binding
F
MLC1
TRR1
GO:0004791
thioredoxin-disulfide reductase activity
F
MLC1
TRR1
GO:0009055
electron carrier activity
F
MLC1
TRR1
GO:0050660
FAD binding
F
MLC1
TRR1
GO:0016491
oxidoreductase activity
F
GAS1
ATG1
GO:0016301
kinase activity
F
GAS1
ATG1
GO:0000166
nucleotide binding
F
GAS1
ATG1
GO:0004674
protein serine/threonine kinase activity
F
GAS1
ATG1
GO:0016740
transferase activity
F
GAS1
ATG1
GO:0004672
protein kinase activity
F
GAS1
ATG1
GO:0005524
ATP binding
F
TRIM6
CCT3
GO:0005524
ATP binding
F
TRIM6
CCT3
GO:0051082
unfolded protein binding
F
TRIM6
CCT3
GO:0000166
nucleotide binding
F
UBL5
BCY1
GO:0001932
regulation of protein amino acid phosphorylation
P
UBL5
BCY1
GO:0007568
aging
P
UBL5
BCY1
GO:0007039
vacuolar protein catabolic process
P
UBL5
BCY1
GO:0007165
signal transduction
P
UBL5
BCY1
GO:0019932
second-messenger-mediated signaling
P
UBL5
BCY1
GO:0007265
Ras protein signal transduction
P
UBL5
BCY1
GO:0007264
small GTPase mediated signal transduction
P
UBL5
BCY1
GO:0046580
negative regulation of Ras protein signal transduction
P
C9orf16
CMP2
GO:0000754
P
C9orf16
CMP2
GO:0007039
adaptation to pheromone during conjugation with
cellular fusion
vacuolar protein catabolic process
C9orf16
CMP2
GO:0006873
cellular ion homeostasis
P
SCGB2A2
MMT1
GO:0006812
cation transport
P
F
P
SCGB2A2
MMT1
GO:0006811
ion transport
P
SCGB2A2
MMT1
GO:0006810
transport
P
SCGB2A2
MMT1
GO:0006879
cellular iron ion homeostasis
P
SCGB2A2
MMT1
GO:0006826
iron ion transport
P
OCM
TFC1
GO:0006350
transcription
P
OCM
TFC1
GO:0006384
OCM
TFC1
GO:0045449
regulation of transcription
P
NRSN2
PDR17
GO:0006869
lipid transport
P
NRSN2
PDR17
GO:0015914
phospholipid transport
P
NRSN2
PDR17
GO:0006810
transport
P
NRSN2
PDR17
GO:0042493
response to drug
P
NRSN2
PDR17
GO:0008654
phospholipid biosynthetic process
P
TRAP1
PRP39
GO:0016071
mRNA metabolic process
P
TRAP1
PRP39
GO:0000395
nuclear mRNA 5'-splice site recognition
P
TRAP1
PRP39
GO:0019953
sexual reproduction
P
TRAP1
PRP39
GO:0008380
RNA splicing
P
TRAP1
PRP39
GO:0006396
RNA processing
P
TRAP1
PRP39
GO:0006397
mRNA processing
P
MKRN1
GLC8
GO:0005978
glycogen biosynthetic process
P
MKRN1
GLC8
GO:0051098
regulation of binding
P
MKRN1
GLC8
GO:0044262
cellular carbohydrate metabolic process
P
MKRN1
GLC8
GO:0005977
glycogen metabolic process
P
MKRN1
GLC8
GO:0007059
chromosome segregation
P
PROL1
ATG2
GO:0030242
peroxisome degradation
P
PROL1
ATG2
GO:0006914
autophagy
P
PROL1
ATG2
GO:0006810
transport
P
PROL1
ATG2
GO:0000045
autophagic vacuole formation
P
PROL1
ATG2
GO:0015031
protein transport
P
PROL1
ATG2
GO:0032258
CVT pathway
P
PROL1
ATG2
GO:0034727
piecemeal microautophagy of nucleus
P
EXOSC8
MRPL20
GO:0032543
mitochondrial translation
P
IL25
GIM5
GO:0007021
tubulin complex assembly
P
IL25
GIM5
GO:0006461
protein complex assembly
P
IL25
GIM5
GO:0006457
protein folding
P
TLX2
DBP7
GO:0000027
ribosomal large subunit assembly
P
TLX2
DBP7
GO:0042254
ribosome biogenesis
P
TLX2
DBP7
GO:0006364
rRNA processing
P
FANCD2
CCL1
GO:0006350
transcription
P
FANCD2
CCL1
GO:0045449
regulation of transcription
P
FANCD2
CCL1
GO:0007049
cell cycle
P
FANCD2
CCL1
GO:0007070
negative regulation of transcription from RNA
polymerase II promoter, mitotic
P
P
FANCD2
CCL1
GO:0006367
P
GO:0006984
transcription initiation from RNA polymerase II
promoter
ER-nuclear signaling pathway
IFIT3
SCS2
IFIT3
SCS2
GO:0006348
chromatin silencing at telomere
P
IFIT3
SCS2
GO:0008654
phospholipid biosynthetic process
P
IFIT3
SCS2
GO:0048309
endoplasmic reticulum inheritance
P
IFIT3
SCS2
GO:0032377
regulation of intracellular lipid transport
P
IFIT3
SCS2
GO:0042992
P
IFIT2
HSK3
GO:0031110
IFIT2
HSK3
GO:0030472
negative regulation of transcription factor import into
nucleus
regulation of microtubule polymerization or
depolymerization
mitotic spindle organization in nucleus
IFIT2
HSK3
GO:0051301
cell division
P
IFIT2
HSK3
GO:0007059
chromosome segregation
P
IFIT2
HSK3
GO:0007067
mitosis
P
IFIT2
HSK3
GO:0007049
cell cycle
P
IFIT1
OSH2
GO:0006887
exocytosis
P
IFIT1
OSH2
GO:0006897
endocytosis
P
IFIT1
OSH2
GO:0015918
sterol transport
P
IFIT1
OSH2
GO:0006869
lipid transport
P
IFIT1
OSH2
GO:0006810
transport
P
IFIT1
OSH2
GO:0030011
maintenance of cell polarity
P
IFIT1
OSH2
GO:0008202
steroid metabolic process
P
CHIC2
RPC82
GO:0006350
transcription
P
CHIC2
RPC82
GO:0006383
transcription from RNA polymerase III promoter
P
LOXL3
LGE1
GO:0006279
premeiotic DNA synthesis
P
LOXL3
LGE1
GO:0006350
transcription
P
LOXL3
LGE1
GO:0006513
protein monoubiquitination
P
LOXL3
LGE1
GO:0016574
histone ubiquitination
P
LOXL3
LGE1
GO:0030435
sporulation resulting in formation of a cellular spore
P
LOXL3
LGE1
GO:0008361
regulation of cell size
P
LOXL3
LGE1
GO:0045449
regulation of transcription
P
LOXL3
LGE1
GO:0016571
histone methylation
P
LOXL3
LGE1
GO:0016568
chromatin modification
P
RBM8A
AIR2
GO:0071031
RBM8A
AIR2
GO:0016073
RBM8A
AIR2
GO:0071037
P
RBM8A
AIR2
GO:0071036
P
RBM8A
AIR2
GO:0071035
P
RBM8A
AIR2
GO:0071039
P
RBM8A
AIR2
GO:0071038
P
RBM8A
AIR2
GO:0043629
P
P
P
P
snRNA metabolic process
ncRNA polyadenylation
P
P
B3GNT2
SUM1
GO:0030466
chromatin silencing at silent mating-type cassette
P
B3GNT2
SUM1
GO:0006348
chromatin silencing at telomere
P
B3GNT2
SUM1
GO:0006270
DNA replication initiation
P
B3GNT2
SUM1
GO:0030435
sporulation resulting in formation of a cellular spore
P
B3GNT2
SUM1
GO:0045449
regulation of transcription
P
B3GNT2
SUM1
GO:0006350
transcription
P
B3GNT2
SUM1
GO:0007088
regulation of mitosis
P
B3GNT2
SUM1
GO:0016481
negative regulation of transcription
P
JMJD5
UBA2
GO:0016925
protein sumoylation
P
JMJD5
UBA2
GO:0019941
modification-dependent protein catabolic process
P
JMJD5
UBA2
GO:0006464
protein modification process
P
JMJD5
UBA2
GO:0008152
metabolic process
P
C10orf119
ERG1
GO:0019748
secondary metabolic process
P
C10orf119
ERG1
GO:0008152
metabolic process
P
C10orf119
ERG1
GO:0055114
oxidation reduction
P
C10orf119
ERG1
GO:0006696
ergosterol biosynthetic process
P
RETN
YBP1
GO:0006979
response to oxidative stress
P
P2RY13
ATM1
GO:0006826
iron ion transport
P
P2RY13
ATM1
GO:0006811
ion transport
P
P2RY13
ATM1
GO:0006810
transport
P
P2RY13
ATM1
GO:0006879
cellular iron ion homeostasis
P
FOXRED1
YDR061W
GO:0006810
transport
P
WSB1
INO80
GO:0006348
chromatin silencing at telomere
P
WSB1
INO80
GO:0006338
chromatin remodeling
P
WSB1
INO80
GO:0006281
DNA repair
P
WSB1
INO80
GO:0006366
transcription from RNA polymerase II promoter
P
WSB1
INO80
GO:0043618
P
WSB1
INO80
GO:0006974
regulation of transcription from RNA polymerase II
promoter in response to stress
response to DNA damage stimulus
WSB1
INO80
GO:0006350
transcription
P
WSB1
INO80
GO:0010552
P
WSB1
INO80
GO:0045449
positive regulation of specific transcription from RNA
polymerase II promoter
regulation of transcription
WSB1
INO80
GO:0042766
nucleosome mobilization
P
WSB1
INO80
GO:0016568
chromatin modification
P
PGM5
MLC2
GO:0051301
cell division
P
PGM5
MLC2
GO:0000003
reproduction
P
PGM5
MLC2
GO:0007049
cell cycle
P
PGM5
MLC2
GO:0000916
contractile ring contraction involved in cytokinesis
P
OFD1
CSR1
GO:0009395
phospholipid catabolic process
P
OFD1
CSR1
GO:0019217
regulation of fatty acid metabolic process
P
OFD1
CSR1
GO:0006869
lipid transport
P
P
P
OFD1
CSR1
GO:0015914
phospholipid transport
P
OFD1
CSR1
GO:0006810
transport
P
OFD1
CSR1
GO:0007047
cell wall organization
P
OFD1
CSR1
GO:0030433
ER-associated protein catabolic process
P
OFD1
CSR1
GO:0044255
cellular lipid metabolic process
P
SURF2
DRE2
GO:0010421
hydrogen peroxide-mediated programmed cell death
P
SURF2
DRE2
GO:0007064
mitotic sister chromatid cohesion
P
SURF2
DRE2
GO:0016226
iron-sulfur cluster assembly
P
A1BG
MCM6
GO:0006350
transcription
P
A1BG
MCM6
GO:0006342
chromatin silencing
P
A1BG
MCM6
GO:0000084
S phase of mitotic cell cycle
P
A1BG
MCM6
GO:0006270
DNA replication initiation
P
A1BG
MCM6
GO:0040029
regulation of gene expression, epigenetic
P
A1BG
MCM6
GO:0006267
pre-replicative complex assembly
P
A1BG
MCM6
GO:0045449
regulation of transcription
P
A1BG
MCM6
GO:0051049
regulation of transport
P
A1BG
MCM6
GO:0006260
DNA replication
P
A1BG
MCM6
GO:0045814
negative regulation of gene expression, epigenetic
P
A1BG
MCM6
GO:0006268
DNA unwinding during replication
P
A1BG
MCM6
GO:0006271
DNA strand elongation during DNA replication
P
A1BG
MCM6
GO:0007049
cell cycle
P
CTDSPL
SEY1
GO:0007029
endoplasmic reticulum organization
P
CTDSPL
SEY1
GO:0016044
membrane organization
P
CTDSPL
SEY1
GO:0006950
response to stress
P
SCGN
ZEO1
GO:0007047
cell wall organization
P
SCGN
ZEO1
GO:0006950
response to stress
P
NR4A3
UMP1
GO:0006974
response to DNA damage stimulus
P
NR4A3
UMP1
GO:0006508
proteolysis
P
NR4A3
UMP1
GO:0006511
ubiquitin-dependent protein catabolic process
P
NR4A3
UMP1
GO:0043248
proteasome assembly
P
BZRAP1
MET6
GO:0008652
cellular amino acid biosynthetic process
P
BZRAP1
MET6
GO:0009086
methionine biosynthetic process
P
BZRAP1
MET6
GO:0006519
cellular amino acid and derivative metabolic process
P
BZRAP1
MET6
GO:0006807
nitrogen compound metabolic process
P
BZRAP1
MET6
GO:0006790
sulfur metabolic process
P
BZRAP1
MET6
GO:0006414
translational elongation
P
BZRAP1
MET6
GO:0046483
heterocycle metabolic process
P
OASL
RPL15B
GO:0006412
translation
P
MUC4
PAM1
GO:0007124
pseudohyphal growth
P
MUC4
PAM1
GO:0009966
regulation of signal transduction
P
MUC4
PAM1
GO:0000003
reproduction
P
MUC4
PAM1
GO:0051301
cell division
P
TMEM9
RAD14
GO:0006974
response to DNA damage stimulus
P
TMEM9
RAD14
GO:0006914
autophagy
P
TMEM9
RAD14
GO:0006281
DNA repair
P
TMEM9
RAD14
GO:0000715
nucleotide-excision repair, DNA damage recognition
P
TMEM9
RAD14
GO:0006289
nucleotide-excision repair
P
CHERP
RPL37A
GO:0006412
translation
P
TPD52L1
CDC3
GO:0000910
cytokinesis
P
TPD52L1
CDC3
GO:0000747
conjugation with cellular fusion
P
TPD52L1
CDC3
GO:0000746
conjugation
P
TPD52L1
CDC3
GO:0007120
axial cellular bud site selection
P
TPD52L1
CDC3
GO:0000902
cell morphogenesis
P
TPD52L1
CDC3
GO:0051049
regulation of transport
P
TPD52L1
CDC3
GO:0007047
cell wall organization
P
TPD52L1
CDC3
GO:0007049
cell cycle
P
TPD52L1
CDC3
GO:0030010
establishment of cell polarity
P
TPD52L1
CDC3
GO:0051301
cell division
P
TPD52L1
CDC3
GO:0051704
multi-organism process
P
CXorf26
URA10
GO:0006207
'de novo' pyrimidine base biosynthetic process
P
CXorf26
URA10
GO:0009116
nucleoside metabolic process
P
CXorf26
URA10
GO:0046132
pyrimidine ribonucleoside biosynthetic process
P
CXorf26
URA10
GO:0006221
pyrimidine nucleotide biosynthetic process
P
PRB4
FAR1
GO:0000746
conjugation
P
PRB4
FAR1
GO:0000750
P
PRB4
FAR1
GO:0000751
pheromone-dependent signal transduction involved in
conjugation with cellular fusion
cell cycle arrest in response to pheromone
PRB4
FAR1
GO:0030447
filamentous growth
P
PRB4
FAR1
GO:0050790
regulation of catalytic activity
P
PRB4
FAR1
GO:0019953
sexual reproduction
P
PRB4
FAR1
GO:0007049
cell cycle
P
PRB4
FAR1
GO:0007166
cell surface receptor linked signal transduction
P
PRB4
FAR1
GO:0019236
response to pheromone
P
PRB4
FAR1
GO:0051301
cell division
P
NPFFR1
RAD51
GO:0000709
meiotic joint molecule formation
P
NPFFR1
RAD51
GO:0000722
telomere maintenance via recombination
P
NPFFR1
RAD51
GO:0051321
meiotic cell cycle
P
NPFFR1
RAD51
GO:0000725
recombinational repair
P
NPFFR1
RAD51
GO:0006281
DNA repair
P
NPFFR1
RAD51
GO:0030491
heteroduplex formation
P
NPFFR1
RAD51
GO:0006974
response to DNA damage stimulus
P
NPFFR1
RAD51
GO:0000724
double-strand break repair via homologous
recombination
P
P
NPFFR1
RAD51
GO:0006310
DNA recombination
P
NPFFR1
RAD51
GO:0006259
DNA metabolic process
P
NPFFR1
RAD51
GO:0042148
strand invasion
P
NPFFR1
RAD51
GO:0007131
reciprocal meiotic recombination
P
BSCL2
FMP41
GO:0006950
response to stress
P
BSCL2
FMP41
GO:0008152
metabolic process
P
MAGEA12
AIM45
GO:0022900
electron transport chain
P
MAGEA12
AIM45
GO:0006810
transport
P
ETV3
CAF20
GO:0006417
regulation of translation
P
ETV3
CAF20
GO:0010606
P
ETV3
CAF20
GO:0006412
positive regulation of cytoplasmic mRNA processing
body assembly
translation
ETV3
CAF20
GO:0017148
negative regulation of translation
P
TAF7L
TSC10
GO:0030148
sphingolipid biosynthetic process
P
TAF7L
TSC10
GO:0006666
3-keto-sphinganine metabolic process
P
TAF7L
TSC10
GO:0008152
metabolic process
P
TAF7L
TSC10
GO:0055114
oxidation reduction
P
TAF7L
TSC10
GO:0018193
peptidyl-amino acid modification
P
LRP4
TAH18
GO:0010421
hydrogen peroxide-mediated programmed cell death
P
LRP4
TAH18
GO:0031329
regulation of cellular catabolic process
P
LRP4
TAH18
GO:0055114
oxidation reduction
P
PRCC
YLR132C
GO:0008380
RNA splicing
P
PRCC
YLR132C
GO:0006397
mRNA processing
P
PCID2
BDH1
GO:0006066
alcohol metabolic process
P
PCID2
BDH1
GO:0034605
cellular response to heat
P
PCID2
BDH1
GO:0008152
metabolic process
P
PCID2
BDH1
GO:0055114
oxidation reduction
P
CSHL1
HAM1
GO:0006974
response to DNA damage stimulus
P
CSHL1
HAM1
GO:0043094
cellular metabolic compound salvage
P
CSHL1
HAM1
GO:0009204
deoxyribonucleoside triphosphate catabolic process
P
CSHL1
HAM1
GO:0018193
peptidyl-amino acid modification
P
RBMX
SMD2
GO:0016071
mRNA metabolic process
P
RBMX
SMD2
GO:0008380
RNA splicing
P
RBMX
SMD2
GO:0000398
nuclear mRNA splicing, via spliceosome
P
RBMX
SMD2
GO:0006397
mRNA processing
P
SCGB2A1
TRR2
GO:0019430
removal of superoxide radicals
P
SCGB2A1
TRR2
GO:0045454
cell redox homeostasis
P
SCGB2A1
TRR2
GO:0006979
response to oxidative stress
P
SCGB2A1
TRR2
GO:0055114
oxidation reduction
P
SCGB2A1
TRR2
GO:0051049
regulation of transport
P
MLC1
TRR1
GO:0019430
removal of superoxide radicals
P
MLC1
TRR1
GO:0045454
cell redox homeostasis
P
P
MLC1
TRR1
GO:0006979
response to oxidative stress
P
MLC1
TRR1
GO:0055114
oxidation reduction
P
TRIM2
SEC66
GO:0015031
protein transport
P
TRIM2
SEC66
GO:0031204
P
TRIM2
SEC66
GO:0030447
posttranslational protein targeting to membrane,
translocation
filamentous growth
TRIM2
SEC66
GO:0006810
transport
P
P
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