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Additional file 1 Table S1 Symbols and names for all annotated candidate genes Symbol AARS ADIPOR2 ATP2B4 BRP44L CASP9 CCR7 CDC6 CDK10 CELA2A CTRC CYM DDX19B EFHD2 EXOSC6 FANCA FBXL14 FBXL21 G3BP1 GLG1 GLRA1 GUCY2D HOXC13 IGFBP4 IMPG1 KRT222 KBTBD1 KRT24-27 LAMTOR LAX1 LECT2 MC1R MRCL NDUFA12 OPTC PDPR PIK3CA PRELP Gene name Alanyl-tRNA synthetase Adiponectin receptor 2 Plasma membrane calcium-transporting ATPase 4 Brain protein 44 Caspase 9, Apoptosis-Related Cysteine Peptidase Chemokine (C-C Motif) Receptor 7 Cell division cycle 6 Cyclin-Dependent Kinase 10 Chymotrypsin-Like Elastase Family, Member 2A Chymotrypsin C (caldecrin) Chymosin ATP-dependent RNA helicase DDX19B EF-Hand Domain Family, Member D2 Exosome Component 6 Fanconi anemia, complementation group A F-Box And Leucine-Rich Repeat Protein 14 F-Box And Leucine-Rich Repeat Protein 21 Ras GTPase-activating protein-binding protein 1 Golgi Glycoprotein 1 Glycine receptor, alpha 1 Guanylate cyclase 2D, membrane (retina-specific) Homeobox C13 Insulin-like growth factor-binding protein 4 Interphotoreceptor Matrix Proteoglycan 1 Keratin 222, Type II Human Kelch-like protein 31 Keratin 24, Type I Late Endosomal/Lysosomal Adaptor, MAPK And MTOR Activator 1 Lymphocyte Transmembrane Adaptor 1 Leukocyte cell-derived chemotaxin 2 melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) Mannose receptor-like precursor NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex, 12 Opticin Pyruvate Dehydrogenase Phosphatase Regulatory Subunit phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha.” Proline/Arginine-Rich End Leucine-Rich Repeat Protein Symbol SPATA2 SPIRE2 TCF25 TGFBI TMEM51 TMEM88 TNS4 UBL4B WC1.3 WIPF2 WNT5B ZC3H11A ZMAT3 AJAP1 ALOX12B ALOX15B ATOX1 CHMP1A CXCL14 DCC DDX19A DNAH2 DNAJC16 EBF1 ERC1 FMOD FRMD4B GNG5 HOXC12 HSPB9 KCNA2 KCNB1 KCNMB3 KIAA1797 MTPN MYO6 NOS1AP Gene name Spermatogenesis Associated 2 Spire-Type Actin Nucleation Factor Transcription Factor 25 (Basic Helix-Loop-Helix) Transforming Growth Factor, Beta-Induced, 68kDa Transmembrane Protein 51 Transmembrane protein 88 Aliases for TNS4 Gene Ubiquitin-Like 4B White Cap1.3 WAS/WASL Interacting Protein Family, Member 2 Wingless-Type MMTV Integration Site Family, Member 5B Zinc Finger CCCH-Type Containing 11A Zinc finger, matrin-type 3 Adherens junctions associated protein 1 Arachidonate 12-lipoxygenase, 12R type Arachidonate 15-lipoxygenase type II Antioxidant Protein 1 Charged Multivesicular Body Protein 1A Chemokine (C-X-C motif) ligand 14 Immunoglobulin Superfamily DCC Subclass Member 1 DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 19A Dynein, axonemal, heavy chain 2 DnaJ (Hsp40) Homolog, Subfamily C, Member 16 Early B-Cell Factor 1 ELKS/RAB6-Interacting/CAST Family Member 1 Fibromodulin FERM Domain Containing 4B Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit Gamma-5 Homeobox C12 Heat Shock Protein, Alpha-Crystallin-Related, B9 Potassium Channel, Voltage Gated Shaker Related Subfamily A, Member 2 Potassium channel, voltage gated Shab related subfamily B, member 1 Calcium-activated potassium channel subunit beta-3 Human Uncharacterized protein Myotrophin Myosin VI Nitric Oxide Synthase 1 (Neuronal) Adaptor Protein PROK1 PTGIS RARA REN RPF1 RPS6KA2 SEMA4A Prokineticin 1 Prostaglandin I2 (prostacyclin) synthase Retinoic Acid Receptor, Alpha Angiotensinogenase Ribosome production factor 1 homolog Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4A SLC16A4 Solute Carrier Family 16, Member 4 SLC25A48 Solute Carrier Family 25, Member 48 SLC22A17 Solute Carrier Family 22 (Organic Cation Transporter), Member 17 Peptide SMARCE1 SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily E, Member 1 SNRPE Small Nuclear Ribonucleoprotein Polypeptide BAF57 SMARCE1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1) NUCB2 OTX2 OVOS2 PDPN PDPR PREP RBBP8 Nucleobindin 2 Orthodenticle homeobox 2. Ovostatin 2 Podoplanin Pyruvate Dehydrogenase Phosphatase Regulatory subunit Prolyl Endopeptidase Retinoblastoma-binding protein 8 SCP2 SERPINA3-8 SFT2D1 WC1 Sterol Carrier Protein 2 Serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin SFT2 Domain Containing 1 White Cap1 ZNF280B zinc finger protein 280B