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Cardiac Output Monitoring in Cardiac Surgery with Cardiopulmonary Bypass K. Lebedinski, A. Vetchinkin St. Petersburg Circulatory Failure After Cardiac Surgery With CPB Hypovolemia Vasoplegia: • Rewarming • SIRS after CPB • Drug or blood reaction Primary Low Cardiac Output: • Ventricular dysfunction • Surgical problems Circulatory Failure: Diagnosis Cardiac Output? Vascular Tone? Preload? The Sources of Principal Hemodynamic Variables CO: measurement SVR: calculation Preload: measurement Clinical group: 32 ASA III-IV male patients, aged 40-75 Surgery: Elective CABG and/or valve replacement with CPB Methods: CO estimation by 6 different methods, in all 913 pair data S/5 General Electric, USA Method: Conventional (pulmonary artery) thermodilution, N=246 NICO2 Novametrix, USA Method: Partial CO2-rebreathing based on differential form of Fick equation, N=473 PiCCO Pulsion, Germany Method: transpulmonary thermodilution followed by continuous pulse wave contour analysis, N=416 Diamant-M Russia Method: Impedance Cardiography with on-line Computer Analysis (Bioimpedance Monitoring), N=428 Sonoline G60S Siemens, Germany Method: Transesophageal echocardiography (TEE), N=113 Method: Adolf Fick principle (1870), N=150 Correlation Between Methods: Before CPB • The best: CTD, TPTD, CO2 and IC • The worst: Fick and TEE Correlation Between Methods: After CPB • Correlations between CTD, TPTD and CO2 remained stable Correlation Between Methods: After CPB • IC became inaccurate! Correlation Between Methods: After CPB • What about Fick and TEE? Small amount of data - ?... Conclusions: • The most relevant cardiac output monitoring methods in cardiac surgery with cardiopulmonary bypass are conventional and transpulmonary thermodilution and CO2 partial rebreathing. • Impedance cardiography, acceptable in nonCPB cases, became inaccurate after the bypass. • Transesophageal EchoCG and Fick method demonstrate poor accuracy in clinical settings. Thank you for the attention!