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1 2 3 4 5 6 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Telencephalon Prosencephalon Optic vesicle Diencephalon Mesencephalon Rhombencephalon Metencephalon Myelencephalon Spinal cord (a) 4 weeks (b) 5 weeks Telencephalon Forebrain Diencephalon Mesencephalon Midbrain Pons Cerebellum Metencephalon Hindbrain Myelencephalon (medulla oblongata) Spinal cord (c) Fully developed Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Cerebral hemispheres Rostral Caudal Central sulcus Gyri Frontal lobe Cerebrum Lateral sulcus Central sulcus Temporal lobe Cerebellum Parietal lobe Brainstem Occipital lobe Spinal cord Longitudinal fissure (a) Superior view (b) Lateral view Precentral gyrus Central sulcus Postcentral gyrus Frontal lobe Parietal lobe Arachnoid mater Insula Temporal lobe Occipital lobe Cerebellum Blood vessels Medulla oblongata (c) Lateral view c: © The McGraw-Hill Companies, Inc./Rebecca Gray, photographer/Don Kincaid, dissections 7 8 9 10 11 12 13 14 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Caudal Rostral Skull Lateral ventricles Dura mater: Periosteal layer Meningeal layer Subdural space Subarachnoid space Arachnoid villus Arachnoid mater Interventricular foramen Superior sagittal sinus Blood vessel Third ventricle Cerebral aqueduct Falx cerebri (in longitudinal fissure only) Pia mater Fourth ventricle Brain: Gray matter Lateral aperture White matter Median aperture Central canal (a) Lateral view 15 16 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Arachnoid villus 8 Superior sagittal sinus Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Arachnoid mater 1 CSF is secreted by choroid plexus in each lateral ventricle. Cerebrum Subarachnoid space Dura mater Lateral ventricle 2 CSF flows through Interventricular foramina into third ventricle. Interventricular foramen 3 Choroid plexus in third ventricle adds more CSF. Third ventricle 1 2 Choroid plexus Third ventricle 3 7 4 Cerebral aqueduct Fourth ventricle 4 CSF flows down cerebral aqueduct to fourth ventricle. Cerebral aqueduct Lateralaper ture 5 Choroid plexus in fourth ventricle adds more CSF. Lateral aperture Fourth ventricle 6 5 6 CSF flows out two lateral apertures and one median aperture. Median aperture 7 CSF fills subarachnoid space and bathes external surfaces of brain and spinal cord. (b) Anterior view 8 At arachnoid villi, CSF is reabsorbed into venous blood of dural venous sinuses. Median aperture 7 Centralcanal of spinal cord Subarachnoid space of spinal cord 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31