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From Gene to Protein: An
exercise in breaking the
code
Genes
(DNA)
Make copies
of itself
New copy
(RNA) is
read and
translated
www.squidoo.com/geneticsresearch
A trait is
expressed
VC: What is phenotype
Amino acids
(protein) are
formed
Cracking the
Code
DNA
VC: Cracking the code
copied and read
RNA
translated
http://entomology.wisc.edu/~goodman/wgr...rch.html
PROTEIN
1. DNA COPIES ITSELF:
Base pairings: A- T
DNA molecule
unzips breaking
the base pairs
forming 2 sides
VC: DNA Replication
VC: How DNA copies itself
C–G
Given the code of a DNA molecule,
what would be the code of the new
DNA strand?
A: TACCGGATGCCAGATCAAATC
What is the other side?
__________________________
B: TACGGGGGCGTAACCACAACT
What is the other side?
__________________________
Given the code of a DNA molecule,
what would be the code of the new
DNA strand?
A: TACCGGATGCCAGATCAAATC
What is the other side?
ATGGCCTACGGTCTAGTTTAG
B: TACGGGGGCGTAACCACAACT
What is the other side?
ATGCCCCCGCATTGGTGTTGA
2. CODE IS READ into RNA. The code of
the new strand (DNA copy) is READ with the T
replaced with a new base Uracil or U to make
RNA.
From #1: (DNA copy)
ATGGCCTACGGTCTAGTTTAG
A: ____________________________________
B: ____________________________________
2. CODE IS READ. The code of the new
strand (DNA copy) is READ with the T replaced
with a new base Uracil or U.
ATGGCCTACGGTCTAGTTTAG
A: ____________________________________
AUGGCCUACGGUCUAGUUUAG
ATGCCCCCGCATTGGTGTTGA
B: ____________________________________
AUGCCCCCGCAUUGGUGUUGA
VC:
From DNA to protein
3. CODE IS TRANSLATED. The code is read in
groups of 3 called codons).
AUGGCCUACGGUCUAGUUUAG
A: ____________________________________
B: ____________________________________
3. CODE IS TRANSLATED. The code is read in
groups of 3 called codons).
AUGGCCUACGGUCUAGUUUAG
A: ____________________________________
AUG GCC UAC GGU CUA GUU UAG
AUGCCCCCGCAUUGGUGUUGA
B: ____________________________________
AUG CCC CCG CAU UGG UGU UGA
Find the Amino Acid sequence that is coded:
Use the following guide.
AUG GCC UAC GGU CUA GUU UAG
A: ____________________________________
AMINO ACID SEQUENCE
AUG
GCC UAC
GGU
A: Methionine-Alanine-Tyrosine-GlycineCUA
GUU
UAG
Leucine-Valine-Stop
AMINO ACID SEQUENCE
AUG GCC UAC GGU CUA GUU UAG
A: Methionine-Alanine-Tyrosine-GlycineLeucine-Valine-Stop
AUG CCC CCG CAU UGG UGU UGA
B: Methionine-Proline-Proline-HistidineTryptophan-Cysteine-Stop
Cracking the
Code
DNA
VC: Cracking the code
copied and read
RNA
translated
http://entomology.wisc.edu/~goodman/wgr...rch.html
PROTEIN
Genes(
DNA)
Make copies
of itself
New copy
(RNA) is
read and
translated
Crossover
(mixing of
code)
www.squidoo.com/geneticsresearch
A trait is
expressed
VC: What is phenotype
Amino acids
(protein) are
formed
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