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More reasons for you to check any food you eat that has nutritional data attached. 1. Acesulfame Potassium Weakens Immunity Acesulfame potassium (acesulfame-K) is often found in other artificial sweeteners like sucralose to hide an unpleasant aftertaste. Although acesulfame potassium does not raise blood sugar levels it does produce insulin secretions. High insulin levels promote inflammatory conditions and weaken immune function. Hypoglycemia is a condition of low blood sugar which can result because this artificial sweetener does not elevate blood sugar. Even in small doses this artificial sweetener may increase risk for atherosclerosis because it causes abnormal functioning of high-density lipoproteins (HDL) which are necessary to maintain optimal cardiovascular health. Disrupted metabolic pathways from acesulfame create abnormal cell activity, genotoxicity, and imbalanced homeostasis. Acesulfame is associated with increased risk of leukemia, thymus cancer, breast cancer, and chronic respiratory disease. 2. Monosodium Glutamate: A Neurotoxin Monosodium glutamate (MSG) is a flavor enhancer and preservative added to many packaged and canned goods. So dangerous, the Arizona Centre for Advanced Medicine believes this product increases the growth of cancer cells in the body and stimulates neurotoxicity. Its consumption is associated with symptoms of headaches, heart palpitations, brains lesions, and Parkinson’s disease. Non-industry supported research concludes that MSG acts like an excitotoxin slowly poisoning cells in the entire body. Monosodium glutamate, like mercury, fluoride, cadmium, and other neurotoxins, is taken up into circulation and accumulates in the NTS (nucleus tractus solitaries). Impairment of this region of the brain is linked to the increased risk for developmental disorders like autism. MSG builds up in the NTS and competes with normal circulatory processes. Unlike other areas of the brain which close openings by the first year of age, parts of the NTS remain open allowing neurotoxins to contaminate the nervous system and brain. For this reason MSG exposure to newborns may result in delayed onset autism. Other research has found that monosodium glutamate is associated with chronic inflammation, liver damage, weight loss resistance, and chronic pain. Autoimmune diseases result when the body’s natural immune response becomes weakened by a constant heightened state. The chronic inflammatory response resulting from MSG increases risk not only for autoimmune diseases but also elevates the risk for infection and cancer. MSG is hidden on food labels under dozens of different names. Just a few examples of the deceptive names include natural flavourings, autolysed yeast extract, textured protein, soy protein, and whey protein isolate. 3. Sucralose (Splenda®) Causes Gut Microflora Imbalance From the way this artificial sweetener has been marketed you would probably assume it is real sugar. You would be wrong. Sucralose (Splenda) is produced with three chlorine atoms in a highly processed series of reactions which results in damaged gut microflora: Biochemist Dr. James Brown states that “sucralose is simply chlorinated sugar.” Sucralose causes inflammation in the kidneys and liver, and damages the thymus gland. The natural antiseptic properties of chlorine damages the human gut creating microbial imbalances. This disturbance causes chronic inflammation and weakened immunity that is associated with the elevated presence of Candida, irritable bowel syndrome, obesity, Crohn’s disease, ulcerative colitis, and cachexia. Increased permeability of the gut including the intestines and colon is seen in cancer patients. Individuals with colorectal cancer, ovarian cancer, and other cancer types have disturbed gut microflora. This condition generally referred to as gut dysbiosis elevates unhealthy bacterial concentrations, lowers the population of beneficial bacteria, causes vitamin and mineral deficiency, and causes a state of hyper-immunity. Gut dysbiosis leads to an array of problems and diseases including cardiovascular, autoimmune, neurological, psychiatric, and cancer. Imbalanced gut microbiota has been evident in patients with colorectal cancer and is also present in conditions associated with cancer, such as obesity. Colorectal cancer and hepatocellular carcinoma are two major cancers linked to abnormal gut composition. Repairing the gut lining, decreasing permeability, increasing mucous, and improving healthy bacterial balance are some of the first strategies for the treatment and healing of patients with these cancers. 4. Aspartame Is Neurotoxic Originally approved in 1981 for use in food, aspartame is 200 times sweeter than sugar. Aspartame is made up of phenylalanine (50%), aspartic acid (40%), and methanol (10%). High concentrations of phenylalanine have been found to cause abnormal serotonin levels in the nervous system resulting in depression and emotional and psychotic disorders. Individuals who regularly consume aspartame have excess phenylalanine in their systems. Phenylketonuria is a disorder in which some individuals cannot metabolise phenylalanine. Therefore, aspartame should never be consumed by infants or pregnant or nursing women. The chemical aspartic acid functions as an excitotoxin, stimulating neurons and destroying nerve cells. Researchers have found that when cancer cells are subjected to aspartame, they directly increased in activity and mobility. The neurotoxin methanol increases in bioavailability when aspartame is subjected to temperatures greater than 86 degrees Fahrenheit. This heating process disturbs methanol formation, breaking it down into formaldehyde causing nervous system damage and carcinogenic activity. Evidence suggests that elevated doses of aspartame increases risk of blood related cancers including lymphoma and leukemia. Because the dose of aspartame from enjoying one or two diet soda beverages has not been associated with health dangers, food manufacturers and many individuals believe the risk of such health problems is low. However, the high prevalence of aspartame food coupled with continuous consumption of the neurotoxin over years weakens nerve function, stimulates cancer growth and metastasis, and may also increase risk for multiple myeloma. 5. Sodium Benzoate Dangers The combination of sodium hydroxide and benzoic acid is added to this water soluble preservative salt to produce a sweetener. Sodium benzoate is added to food and beverages like energy drinks and soda. Neurodevelopmental disorders such as ADHD, asthma, and other inflammatory disorders have been linked to sodium benzoate consumption. Vitamin C, found as ascorbic acid, is also added to many popular beverages. When sodium benzoate is combined with ascorbic acid, the two form a highly carcinogenic compound − benzene. Benzene is strongly linked to cancers including leukemia and lymphoma. Many research groups, including the International Agency for Research on Cancer (IARC), state that the evidence for sodium benzoate to cause cancer in humans is strong enough to classify this agent as carcinogenic. Benzene alone stimulates stress and oxidative damage to DNA inducing cellular abnormalities and increasing risk for the development of cancer. Unfortunately a lack of a complete understanding involving the pathogenesis of cancers like leukemia and lymphoma have organisations timid to classify this sweetener as definitely cancer-causing. Sodium benzoate is commonly used as a food preservative and also in many soft drinks to intensify flavour. On a label, look for E211 which is its food additive number. From the work my colleagues have researched, I recommend the best course of action is for you to decide which foods pose harm to your body and consider the exposure risks yourself, checking what is on the label of your protein powders, sports drinks and processed food. Pat Reeves November 2016 Sources and References Direct and indirect cellular effects of aspartame on the brain Aspartame ingestion and headaches: a randomised crossover trial Adverse reactions to aspartame: double-blind challenge in patients from a vulnerable population Effects of aspartame metabolites on astrocytes and neurons Formaldehyde, aspartame, and migraines: a possible connection The effect of artificial sweetener on insulin secretion. 1. The effect of acesulfame K on insulin secretion in the rat (studies in vivo) Long-Term Artificial Sweetener Acesulfame Potassium Treatment Alters Neurometabolic Functions in C57BL/6J Mice Monosodium glutamate (MSG): a villain and promoter of liver inflammation and dysplasia Neonatal monosodium glutamate treatment causes obesity, diabetes, and macrovesicular steatohepatitis with liver nodules in DIAR mice Splenda alters gut microflora and increases intestinal p-glycoprotein and cytochrome p450 in male rats Sodium benzoate-rich beverage consumption is associated with increased reporting of ADHD symptoms in college students: a pilot investigation Asthma and intolerance to benzoates Possible mechanisms of carcinogenesis after exposure to benzene American Cancer Society Modified Apolipoprotein (apo) A-I by Artificial Sweetener Causes Severe Premature Cellular Senescence and Atherosclerosis with Impairment of Functional and Structural Properties of apoA-I in Lipid-Free and Lipid-Bound State Cancer Research UK Arizona Center for Advanced Medicine: MSG Systemic effects of gut microbiota and its relationship with disease and modulation Proposed Toxic and Hypoxic Impairment of a Brainstem Locus in Autism The Dangers of Artificial Sweeteners