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AGE DIFFERENCE IN CERVICAL NEOPLASIA DISTRIBUTION AMONG WOMEN ATTENDING A HOSPITAL BASED AND PERIPHERAL SCREENING PROGRAMMES Dr.Kalavathy Mathurchennath1, Saritha.V.N, Sujathan.K, Preethy Sara George 1 Assistant Professor, Regional Cancer Centre, Trivandrum, Kerala, India Background • Cervical cancer continues to be the second common malignancy among females of India and Kerala, the rate of which is around 8/100,000/year in Trivandrum • Regional Cancer Centre (RCC), Trivandrum, India, runs two parallel cervical cancer screening programmes. One regular pap screening in a tertiary Women & Children Govt hospital, Trivandrum(Group1) and second a peripheral screening programme in different Govt Primary Health Centres (PHC) of Trivandrum (Group2) Objective • To see the difference in incidence and age distribution of cervical neoplasia among women attending hospital based and peripheral screening programmes Methodology • Hospital based screening programme conducted regularly twice in a week in the Govt Women & Children Hospital, Tycaudu, Trivandrum • Women attending the Gynaec OPD are subjected for routine pap Smear examination Methodology …..cont.. • Peripheral screening programmes are conducted in 1-2 Govt PHCs in a week. All PHCs in the district are expected to be covered within a period of 18 months. • The women for the Pap Smear screening are motivated by the Accredited Social Health Activist (ASHA) female workers. Methodology.. Cont… • For both Group1 and Group2, the Pap Smear collection is done by the same team of health staff from RCC. • Socio demographic details of each woman subjected for Pap smear is collected as a routine in all the cases. Results • Data of a total of 4991 women from Group1 and 3033 from Group2 were analysed • .32% of Group1 and .36% of Group2 had Low grade Squamous Intraepithelial Lesions (LSIL) • The mean age of incidence of LSIL was 45 in Group1 and 44 in Group2 Results ..cont.. • The incidence of Highgrade Squamous Intraepithelial Lesions (HSIL) was 1.1% in Group1 and .32% in Group2. • The mean age of incidence of HSIL was 54.65 in group1 and 43.3 in Group2 and this difference was statistically significant (p value .014) Discussion • The almost same LSIL incidence in both groups is expected and the mean age of incidence is also same • The hospital group has a higher incidence of HSIL as it expected from a high risk group. • The mean age of incidence of HSIL is significantly lower among the peripheral screened population . This has a great public health importance as it helps to detect asymptomatic women with HSIL who have never been to a hospital at an early age and get treated and arrest the development of cervical cancer