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Name_______________________ mRNA Proverbs The genetic code is written in units called codons. Each codon stands for one of the 20 amino acids that the body needs to make specific proteins that perform a specific function. In this exercise, we will be making sentences using the same principles of genetic coding. 1. Given the list of mRNA Codons and the letters or punctuation they represent, figure out the proverb that is written by the codons. Note: The string of letters represents the way information may be stored on the chromosome and the way mRNA may leave the nucleus. Between ‘sentences’ there is junk code. Be sure to find a start codon BEFORE you start reading, and after a stop codon, don’t keep reading until you find another start codon. Don’t read triplets until you find a start codon! 2. Choose a sentence and write the DNA strand that the mRNA was transcribed from. (Do this on back. The last line will be easiest.) 3. For the alphabet, write the tRNA anticodons. (Do this on the back.) AUG-start codon (signals that the mRNA strand should start being read at the next codon) AAA- a UCU- b CCC- c UGU- d UAU- e UUC- f GGG- g UAC- h AUA- i UGC- j UUA- k UCA- l UGG- m CUU- n AUU- o CCU- p CAU- q CGU- r CUC- s CAC- t UUU- u CGC- v CAG- w CGG- x GUU- y GCU- z GAG- space GGA- apostrophe UAA- STOP with a period UAG- STOP with a question mark UGA- STOP with an exclamation point (stop codons signal that the genetic sentence has ended) Here goes… UGUAUUCUUGGACACGAGCUCCACAAACGUCACGAGGUUUAUCACAUGCCUUAUAUUCCU UCAUAUGAGAUACUUGAGGGGUCAAAACUCCUCGAGUACAUUUUUCUCUAUCUCGAGCUC UACAUUUUUUCAUGUCUUGGACACGAGCGUUUUCUUGAGAAACGUAUUUUUCUUUGUGAG CUUAAAUUAUAUUGUUGAUUUGGGCCCAAACCCCCCCCCCCCCAUGUGUAUUCUUGGACAC GAGUCUAUACACUAUGAGCACUACUAUGAGUACAAACUUUGUGAGCACUACAAACACGAG UCAAUUAUUUUACUCGAGUGUAUACGUCACGUUUAAUGGGGGGGGAAAAAAAAAAAAAUG AUACACGGACUCGAGAAAUCACAGAAAGUUCUCGAGUGUAAACGUUUAUAUCUCCACGAG UCUUAUUUCAUUCGUUAUGAGUGUAAAGUUUCAAUAGGGUACCACGAGCUCAAACGCAUA CUUGGGCUCGAGCACAUAUGGUAUUAAGGCGGGGGGGGGGGGAUUUUUCUUUGUUGAUUU UUUUUUUUUUUUUUUUUAUCAAGAUAUAUAUAUAAUGGUUAUUUUUGAGCCCAAACUC GAGUCAUAUAAAUGUGAGAAAGAGUACAUUCGUCUCUAUGAGCACAUUGAGCAGAAACAC UAUCGUGAGUCUUUUCACGAGCACUACUAUCUUGAGCAGUACAAACACUAGGAGGAGAGA GAGAGGAGAGAGAGUUGUUGGUUGGUUAUGAAAGAGCCUUAUCUUCUUGUUGAGCUCAAA CGCUAUUGUGAGAUACUCGAGCUUAUUCACGAGUGGUUUCCCUACUAAAGAGAGAGAAUG AAACUUGAGAUAUGUUCAUAUGAGUGGAUACUUUGUGAGAUACUCGAGCACUACUAUGAG UCUUAUCUCCACGAGCAGAAAGUUGAGCACAUUGAGCGUUAUUCAAAACGGUAAGGGGGG GGGGGGGGGGGGGGGGGGGGAUGGGGAUUAUUUGUGAGUGCAUUUCUUGAAAAAAAAAA Name_______________________ Perform #2 and #3 from the directions on the front in the space provided: 2) 3) Write the tRNA anti-codons for the alphabet underneath the mRNA codons: AUG-start codon (signals that the mRNA strand should start being read at the next codon) AAA- a UCU- b CCC- c UGU- d UAU- e UUC- f GGG- g UAC- h AUA- i UGC- j UUA- k UCA- l UGG- m CUU- n AUU- o CCU- p CAU- q CGU- r CUC- s CAC- t UUU- u CGC- v CAG- w CGG- x GUU- y GCU- z GAG- space GGA- apostrophe UAA- STOP with a period UGA- STOP with an exclamation point UAG- STOP with a question mark (stop codons signal that the genetic sentence has ended) Thought questions: 4) What is the advantage of having meaningless code at the beginning and the end of a strand of DNA or RNA? 5) Why is the DNA code stored in groups of three nucleotides instead of groups of one or two or four or more?