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The Endocrine System The Pituitary Low magnification – the entire Pituitary Gland Pituitary Stalk Posterior Pituitary Pars Intermedia Pars Tuberalis Anterior Pituitary High mag of the Anterior Pituitary – note eosinophilic and basophilic cells Immunohistochemictry of the Anterior Pituitary Growth Hormone ACTH TEM of the Anterior Pituitary – note different granule morphology C – corticotrophs (ACTH); G – gonadotrophs (FSH,LH) S – somatotrophs (growth hormone); T Thyrotrophs (TSH) ; F – fenestrated capillary High mag of the Posterior Pituitary – neurons, capillaries, and pituicytes High mag of the Posterior Pituitary – note Herring Bodies (arrow) TEM of the Posterior Pituitary UN -unmyelinated neuron; asterisks – Herring Body The Thyroid & Parathyroids High mag of thyroid follicles – note Parafollicular or C-Cells (arrows) Low Magnification of the Parathyroid Gland Parathyroid Gland – note small dark staining chief cells and larger, eosinophilic oxyphil cells The Adrenal Glands Low magnification of the Adrenal Gland Cortex Medulla Cortex Adrenal Cortex Zona Glomerulosa Zona Fasciculata Zona Reticularis Adrenal Cortex Zona Glomerulosa (clumps, cords, and follicle like structures Zona Fasciculata (cords of spongiocytes) Adrenal Gland Zona Fasciculata cords of spongiocytes Zona Reticularis darker staining cells Adrenal Medulla The Islets of Langerhan Low magnification of the Pancreas with Islets of Langerhans (arrows) High mag of an Islet – note Beta cells and more eosinophilic Alpha2 cells Acini Alpha Cells Immunohistochemistry of a pancrearic Islet of Langerhans Glucagon Insulin Pineal Body The Seat of the Soul The Third Eye Pineal Gland N – neuroglia P –pinealocytes S – Brain Sand