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醫院負壓隔離病房之維護 衛生署 疾病管制局 中區傳染病防治醫療網 王任賢 指揮官 Negative Pressure rooms.. With current methods, the entire room is potentially contaminated by infectious droplets Mechanical ventilation • Is created by using a fan to force air exchange and to drive air flow • Works by generating negative pressure in the room to drive airflow inward To be effective, it is essential that: • • • All doors and windows kept closed A minimum of 12 ACH is maintained The ventilation system is well-designed, maintained and operated Principles of ventilation Which is an easier way to extinguish the flame? • Inhale (pull, exhaust) • Exhale (push, supply) Hospital Ventilation Guidelines and Standards CDC’s recommendations Engineering Control Local Exhaust Ventilation (i.e. source control) General Ventilation Air cleaning (HEPA filter, UVGI) CDC’s recommendations General Ventilation considerations Dilution and removal of contaminants Air-flow patterns within room Air-flow direction in facilities Negative pressure in rooms TB isolation rooms CDC’s recommendations for Airborne Infection Isolation (AII) Isolation of Patient infected with organisms spread via airborne droplet nuclei <5 um in diameter ≥ 6ACH for construction before 2001 ≥ ≥ 12 ACH for new construction as of 2001 Negative pressure from corridor into the room Air preferably exhausted to outside Air may be recirculated, return air filtered through HEPA WHO Hospital Infection Control Guideline for SARS and Recommendations in Descending Order of Preference Negative pressure rooms with the door closed Single rooms with their own bathroom facilities Cohort placement in an area with an independent air supply, exhaust system and bathroom facilities Two ways to dilute and remove contaminated air First choice: Single pass Re-circulation + HEPA filtration Rooms in a health facility Designs to provide air mixing exhaust Airflow patterns are affected by: • • • • Air temperature hcw Location of furniture Space configuration supply Movement of health care workers (hcw) exhaust hcw Short circuiting • Clean air is removed before it is mixed with room air • Contaminated air in the room is not effectively diluted or removed supply exhaust Nurse room (Positive) 200 m3/h 225 m3/h 135 m3/h 135 m3/h 225 m3/h 200 m3/h What is negative pressure? Patient room (Negative) 25 m3/h Genesis of Negative Pressure System 負壓系統的誕生 負壓抽氣扇 Negative Pressure Exhaust Fan 吸音板 – 減少噪音 Sound Absorption Board – Reduce Noise 防風防雨 – 防止空氣倒流 Fan Cowl – Reduce Back Pressure 輕便趟門加強負壓效果 Light Weight Folding Door 演進期 隱藏式天花抽氣扇 Recess type exhaust fan HEPA過瀘器 0.3 微米 99.97%效率 HEPA Filter 0.3 Micron 99.97% efficiency 防回流氣閘 Non-return Damper 成熟期 DUCT SupplySUPPLY AirAIRDuct 送風喉 4-BED WARD MODULE 4人病房 Exhaust AirDUCT Duct EXHAUST AIR c/w AIR GRILLES c/w air grilles 抽風喉 Negative pressure room • Air flows into room, from higher to lower pressure • • • 10% flow differential is minimum required Keep doors and windows closed Monitor to ensure negative pressure is maintained AII Rooms AII Rooms • • • • Maintain continuous negative pressure (2.5 Pa) in relation to the air pressure in the corridor and ensure monitoring Ensure that rooms are well sealed Provide ventilation to ensure > 12 ACH for new and renovated rooms and > 6 ACH for existing rooms Direct exhaust air to the outside, away from air intake and populated areas. If this is not practical, air from the room can be recirculated after passing through a HEPA filter, ?UVGI Guidelines • 2001 AIA “Guidelines for Design and Construction of Hospital and Health Care Facilities - ????NEW July 2006 • 2003 CDC “Guidelines for Environmental Infection Control in Health-Care Facilities” • 2004 JCAHO “Environment of Care – Essentials for Health Care” Fourth Edition The Americans Institute of Architects (AIA) Joint Commission on Accreditation of Healthcare Organizations (JCAHO) What about an anteroom? AIA Guidelines Section: 7.2.C Airborne Infectious Isolation Rooms does not require anterooms. The requirement for an anteroom was dropped in the 199697 edition of the Guidelines on the basis of a study. CDC Guideline: Does not require anteroom. For Viral Hemorrhagic Fever and Smallpox, use AII preferably with an anteroom – if not available use industrial-grade HEPA filters to provide additional ACH JCAHO EC Standard: No reference to anterooms ASHRAE’s Design Manual (American Society of Heating, Refrigeration, and Air-conditioning Engineers) “HVAC Design Manual for Hospitals and Clinics” 2003 Chapter 12: Room Design On negative air pressure, as is required for Airborne Infectious Isolation Rooms: “…Through dilution, a 500 cubic feet anteroom (for example) with an AVM of 50 cubic feet would experience a 90 percent reduction in the transmission of contaminated air to and from the isolation room. An anteroom is recommended as a means of controlling airborne contaminant concentration via containment and dilution of the migrating air.” Why add an anteroom or airlock? • • • To provide a barrier against loss of pressurization, and against entry/exit of contaminated air into/out of isolation room when the door to the airlock is opened To provide a controlled environment in which protective garments can be donned without contamination before entry into and exit out of room To provide a controlled environment in which equipment and supplies can be transferred fro the isolation room without contaminating the surrounding area Anterooms Negative Pressure System Verification TB transmission in a TB dispensary, Russia Checking airflow in the TB dispensary Exhaust ventilation Where does the air go? Where does the air go? Exhaust Supply Exhaust Supply Routine monitoring, recording The operation of ventilation systems should be regularly monitored Is the air moving? Is it moving in the right direction? Record performance and dates of all routine monitoring activities Maintenance and inspection of natural ventilation systems Are the windows open? Designate a person to routinely inspect Record results Air Pressure Balancing To prevent escape of droplet nuclei, negative pressure To maintain pressure relationship – clean to dirty Monitoring Negative Air Pressure • Pressure-measuring devices - Measure pressure at the bottom of the door - Audible warning with a time delay - Check continuous monitoring devices at least monthly using smoke tubes Airflow Pattern Air flowing from corridor, through anteroom into isolation room Temperature differential Vaneometer (風速計) Smoke Trail Test (STT) Air flow – Vertical Air flow - Horizontal Negative pressure evaluation • • • • Smoke tube Pressure sensor Flutter strips Velocity meter Smoke Test • • Checked daily • If room air cleaners are used they should be running • Door must be closed Hold 2 inches from bottom of door Smoke test to visualize air movement Air Purification Systems Air filtration system Ultra-Violet light Ozone Air filtration System Some common air contaminants Size (Microns) Pollen : 5 – 100 Virus : 0.001 – 0.05 Aerosol : 0.005 – 50 Human Hair : 70 – 100 Bacteria : 0.35 – 10 Tobacco smoke : 0.01 – 0.5 Household dust : 0.05 – 100 Air filtration System - Air Filters Pre-filters Washable panel filter < 50% Disposable filter < 50% Final filters High Efficiency Filter (Bag filter) = 85~95% High Efficiency Particulate Air (HEPA) filter = 0.3 micron & 99.97% Ultra-Violet (UV) Light – nm- nanometer Vaccum UV – UVV 90-200 nm Short Wave UV – UVC 200-280 nm Middle Wave UV – UVB 280-320 nm Long Wave UV – UVA 320-400 nm Greatest Germicidal Effectiveness – 250265 nm Ultra-Violet – Factors Affecting Killing Rate Air Velocity – Higher velocity, more UVC energy Temperature – Within the system, too cold, too hot, too humid, etc. Relative Humidity (RH) – Higher RH, more UVC energy UV Light source location – Before or after the object e.g. ducting, fan coil units Ultra-Violet - UV Lamp Efficiency (Information source from RoboClean (HK) Co., Ltd.) Ultra-Violet - Safety Avoid exposure to UV rays e.g. eyes, skin problem Improve Ventilation when UVV is used ( generation of Ozone) Avoid direct exposure of plastic material UV Radiation • Used to supplement other engineering controls • Duct Irradiation • - To recirculate air from an isolation room back into the room. - Used in general use areas where air is recirculated back into general ventilation Upper Room Air Irradiation - Mounted on ceiling or wall Ozone (O3) -臭氧之功能 殺菌 防腐 保鮮 解毒 醫療 增氧 美容 漂白 Ozone (O3) -臭氧的濃度國制上的標準 國際臭氧協會規定 0.05ppm(10小時/日) 美國國家標準規定(FDA) 0.05ppm (8小時/日) 德國國家標準規定0.10ppm 日本國家標準規定0.10ppm 法國國家標準規定0.12ppm Measuring Equipment a) Air Flow Measurement Anemometer b) Temperature Measurement Thermometer 同心同德 工程人員 Engineering team 醫生 Doctors 感染控制組 Infection control team 護士 Nurses 醫院行政 Hospital Administration 懇請賜教