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Table S3. Differentially upregulated genes in LS-matrigel compared to BM-MSC. Gene Symbol Gene Name Genbank Accession FC([LS-matrigel] vs [BM-MSC]) WNT2 wingless-type MMTV integration site family member 2 NM_003391 116.163155 WISP2 WNT1 inducible signaling pathway protein 2 NM_003881 103.98407 RCAN2 regulator of calcineurin 2 NM_005822 91.014725 IRX1 iroquois homeobox 1 NM_024337 65.25024 IGFBP2 insulin-like growth factor binding protein 2, 36kDa NM_000597 60.87173 IGFBP5 insulin-like growth factor binding protein 5 NM_000599 57.479874 CPZ carboxypeptidase Z NM_001014448 51.587616 RAMP1 receptor (G protein-coupled) activity modifying protein 1 NM_005855 49.492893 AQP1 aquaporin 1 (Colton blood group) NM_198098 47.68956 CMKLR1 chemokine-like receptor 1 NM_001142343 47.164062 GAS1 growth arrest-specific 1 NM_002048 44.514366 RGS16 regulator of G-protein signaling 16 NM_002928 44.092167 FBN2 fibrillin 2 NM_001999 43.543026 PCSK9 proprotein convertase subtilisin/kexin type 9 NM_174936 39.846733 IGDCC4 immunoglobulin superfamily, DCC subclass, member 4 NM_020962 38.72163 OSR2 odd-skipped related 2 (Drosophila) NM_053001 34.215805 FBLN1 fibulin 1 NM_001996 33.81331 TMEM130 transmembrane protein 130 NM_152913 33.61986 SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B NM_004636 33.126236 FBLN1 fibulin 1 NM_001996 30.188076 hCG_1994695 similar to hCG1994695 NR_026913 29.96652 JAM2 junctional adhesion molecule 2 NM_021219 29.720497 ARHGAP28 Rho GTPase activating protein 28 NM_001010000 26.640345 EXPH5 exophilin 5 NM_015065 26.30286 FMOD fibromodulin NM_002023 26.207024 PITX2 paired-like homeodomain 2 NM_153426 23.72219 FBLN1 fibulin 1 NM_006486 23.1944 ADM adrenomedullin NM_001124 22.93511 SULF2 sulfatase 2 NM_018837 22.92587 CRABP2 cellular retinoic acid binding protein 2 NM_001878 22.573261 C10orf10 chromosome 10 open reading frame 10 NM_007021 22.004457 IL17RD interleukin 17 receptor D NM_017563 21.870169 OGN osteoglycin NM_033014 21.806427 CUGBP2 CUG triplet repeat, RNA binding protein 2 NM_001025077 19.699055 SLIT3 slit homolog 3 (Drosophila) NM_003062 19.293352 COL14A1 collagen, type XIV, alpha 1 NM_021110 18.272284 ADAM33 ADAM metallopeptidase domain 33 NM_025220 17.959604 FAM174B family with sequence similarity 174, member B NM_207446 17.270542 CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 NM_000784 16.833443 MAP2K6 mitogen-activated protein kinase kinase 6 NM_002758 16.517181 CYB5R2 cytochrome b5 reductase 2 NM_016229 16.309109 MSX2P1 msh homeobox 2 pseudogene 1 NR_002307 16.186678 CLDN23 claudin 23 NM_194284 15.727608 CYB5R2 cytochrome b5 reductase 2 NM_016229 15.632573 IRX2 iroquois homeobox 2 NM_033267 15.422464 FAM46C family with sequence similarity 46, member C NM_017709 15.37971 CUGBP2 CUG triplet repeat, RNA binding protein 2 NM_001025076 14.707707 ASS1 argininosuccinate synthetase 1 NM_000050 14.5275755 SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) NM_000337 14.356614 CAND2 cullin-associated and neddylation-dissociated 2 (putative) NM_012298 14.288822 GPNMB glycoprotein (transmembrane) nmb NM_001005340 14.0712185 ASS1 argininosuccinate synthetase 1 NM_000050 13.892227 IRX2 iroquois homeobox 2 NM_033267 13.4494095 CDON Cdon homolog (mouse) NM_016952 12.851442 TMEM119 transmembrane protein 119 NM_181724 12.299345 PDK4 pyruvate dehydrogenase kinase, isozyme 4 NM_002612 12.107496 ADAMTSL4 ADAMTS-like 4 NM_019032 11.8018 COLEC12 collectin sub-family member 12 NM_130386 11.321659 NOVA1 neuro-oncological ventral antigen 1 NM_002515 11.0360365 PCDH18 protocadherin 18 NM_019035 10.957617 CNTN3 contactin 3 (plasmacytoma associated) NM_020872 10.944424 MTMR9L myotubularin related protein 9-like NR_026850 10.895938 C1R complement component 1, r subcomponent NM_001733 10.602338 DPP4 dipeptidyl-peptidase 4 NM_001935 10.319492 DIRC3 disrupted in renal carcinoma 3 NR_026597 10.124143