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Term 2, 2012 WOODLEIGH SCHOOL YEAR 8 – THE HUMAN BODY PART C: DISEASE AND IMMUNITY Science Faculty 1 DISEASE AND THE IMMUNE SYSTEM SCIENCE IN ACTION: IMMUNITY OUR PROTECTION Sir Gustav Nossal, a noted Australian scientist, was Australian of the Year in 2000. Sir Gustav received this award for his lifetime’s work in medical research as an immunologist—a person who studies immunity or the resistance to disease. Our bodies recognise foreign antigens (proteins) on the cells of bacteria and viruses, and make antibodies to destroy them. Once antibodies have been produced against a virus, for example the measles virus, the body retains a memory of this is, so that if the virus comes back again, the body can produce antibodies very quickly to destroy the virus before it can take hold. This is why we usually get a disease like the measles only once. This is called immunity. Because so many children used to die from childhood diseases, scientists developed a way of exposing the child to a disease without them getting the disease itself. This is called immunisation. A small amount of antigen is taken from the organism that causes the disease. This is the vaccine. It is then injected into the child’s body, and the child then produces antibodies against the disease. If enough children are immunised, infectious diseases such as measles and whooping cough can be kept under control, and, hopefully, eliminated in the future. For that to happen, over 95% of children need to be immunised. In the past, immunisation programs have reduced the incidence of diseases such as whooping cough (pertussis). 2 However, in 1996 there were 1007 cases of whooping cough reported in Victoria. Immunisation rates in Australia had fallen to a low of 52% by 1997. Because of the threat of outbreaks of disease, the Australian Government is encouraging parents to make sure that their children are fully immunised. Questions 1. What is immunology? 2. Explain what is meant by immunity. 3. What is the difference between antibodies and antigens? 4. Why is immunisation important? 5. Babies can now have the hepatitis B vaccination soon after they are born. What are the symptoms of hepatitis B? 3 MY FAVORITE DISEASE Your Task Working on your own or as pairs you are to investigate a disease and give a report to the class either as: A short presentation report. For example, a poster (including 250 – 400 words), web page (with 250 – 400 words) or power point presentation (of about 6 – 8 slides with about 250 – 400 words), or A short research report of between 600 – 700 words including relevant tables, diagrams and flow charts. First - Choose a disease that is caused by a pathogen (a disease causing agent such as a bacteria or virus). Include the following information in your report: 1. The common and scientific name of the pathogen. 2. How the pathogen causes the disease in the host. Why do you feel sick? 3. Symptoms of the disease. What happens when you are infected? 4. How the pathogen is distributed. How does it get from one host to the next? 5. How does the first line of defence usually protect you against this disease? 6. How do the second and third lines of defence keep you well, if the pathogen gets past the first line of defence. 7. What can be done for you if you have the disease? How can you be helped not to get it and how can you be helped if you do get it? Good diseases to investigate are Mumps, Measles, Chicken Pox, Glandular Fever, Malaria, Cholera, Influenza, Tetanus, Diptheria, Ebola, HIV/AIDS, Syphillis, Gonorrhea, to name a few. 4 Marking Scheme Criterion 1. Collect the information you need for the project. The seven The answers to questions are all the seven answered questions display correctly. a detailed knowledge of the relationship between the host and the pathogen. 1 1 2 2 3 3 4 5 6 Criterion 2. Use of the scientific language Criterion 3. Presentation The key concepts have been identified. The report logically presents the answers to the questions, using references. The report is presented in a neat and attractive manner. 1 2 3 4 5 1 2 1 2 3 4 The key concepts have been explained correctly in the answers to the questions. 1 2 3 Any issues have been identified and discussed. 1 2 Total Score 5 Student Designed Experiment: Catching Bacteria Where do you find bacteria? How would you catch them? As a whole class we will design a system to catch bacteria and then try and work out where they can be found at Woodleigh School. You will need: Hypothesis Aim Method Safety Materials Results/Observations Discussion/Conclusion Student Designed Experiment: Killing Bacteria Many people believe that they can control the spread of bacteria using all sorts of things: Disinfectants, Antibiotics, Garlic, etc. Design an experiment to test which substances are most effective at controlling the growth and spread of bacteria. You will need: Hypothesis Aim Method Safety Materials Results/Observations Discussion/Conclusion 6