Survey
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Basic Care of the Dementia Patient Assisted Living Association of Alabama Hyatt Regency Wynfrey Hotel September 28, 2016 Andrew S. Duxbury MD FACP – Professor Division of Gerontology and Geriatric Medicine University of Alabama at Birmingham Who Are The Elderly? They are not a single population What is true for one subpopulation may not be true for another Aging concerns are universal The process of aging hasn’t changed over time – attitudes have The Age Wave Approaches The Rise Of The Oldest Old Changing Social Attitudes Towards Aging Denial of realities of aging Disappearance of aging from public space Removal of aged from family life Lack of aging role models in pop culture Defining Elder Populations The Chronologic Definition of Age The Functional Definition of Age The Fifteen Year Definition of Age The Older Adult and the Health Care System: A Critical Intersection Older adults will increase from 14% to 22% of the population Older adults use roughly 1/3 health services and this is expected to increase Older adults are the heaviest consumers of medication and medical equipment Older adults wish to age in place – the system often has other ideas Basic Human Ecology Humans, like other species, adapt their environment to suit their needs In turn, individuals are shaped by their environments and are changed by experience Maintaining an independent existence depends upon the individual’s abilities to adapt to both internal and external change Function is a measure of the ‘fit’ between an individual and their environment of choice Function In Graphic Terms Function Person Environment Function in the Face of Change Environment Person Internal Change External Change Restoration Balance Changed Person Changed Environment Acute vs. Chronic Disease ACUTE Rapid onset Amenable to quick diagnosis and restorative measures Can be completely removed from the body CHRONIC Insidious onset Often easily diagnosed, can be ameliorated but effects cannot necessarily be removed Usually a long term or life long condition Top Twelve Health Conditions of the Older American Atherosclerosis (Coronary disease and stroke) Cancer Hypertension Diabetes Arthritis Sensory impairment Chronic lung disease Kidney failure Dementing illness Depression Incontinence Osteoporosis/Fracture Dementia – Arcs of the Disease Function Alzheimer’s Ischemic Vascular Frontal Lobe Time How Should We Approach Dementia? As a society – how do we want to take care of dementia patients? Do we want to regard dementia patients as worthy of our attention or do we want to make them invisible? Is dementia a disease where we wish to expend shrinking medical resources? Given the complexity of the human brain, is dementia a disease that we can even begin to understand? Is Dementia Inevitable? Have we become too successful at eliminating other diseases? If we could remove dementia, what would arise to take it’s place? Evidence that dementia may be a life long process – The Nun’s Study Dementia Permanent loss of mental abilities caused by damage to brain cells NOT a “normal” part of aging! The common end result of many entities diseases traumas infections drugs More than “confusion” Many things can interfere with memory Being overloaded; having too much going on at one time Medications, even ones taken according to directions Illness and disease that are unrelated to brain disease Unfamiliar surrounding such as relocation or hospitalization Dementia: Essential Features Progressive loss of intellectual abilities . . . MEMORY impairment Short-term early Long-term later Loss of LANGUAGE Loss of ability to express oneself Loss of ability to understand what is said Dementia: Essential Features Loss of PURPOSEFUL MOVEMENT Has the physical ability Can’t perform the task (e.g., getting dressed) Loss of ability to accurately interpret SENSORY INFORMATION Cannot understand what is seen, heard, felt Not related to sensory impairment Dementia: Essential Features Impairments in . . . Abstract thinking Ability to reason Judgement Impulse control Personality changes Not “him/herself” Dementia: Essential Features Lost abilities result in CHANGES . . . Personality Behavior Emotion Get away from me, you big fat slob!! You #@!!!#*!!! “My mother would never say such a thing!” Types of Dementing Illness Alzheimer’s Disease Ischemic Vascular Dementia Frontal Lobe Dementia Lewy Body Dementia Pick’s Disease Creutzfeld-Jakob Disease Parkinson’s Disease Stages of Disease: The FAST (Functional Assessment Staging) Scale Seven Stage Scale often used in clinical practice and research to assess the abilities of a patient with Alzheimer’s disease Stage 1 - Normalcy No impairments No memory problems evident to individuals, families or medical professionals on examination Stage 2 – Very Mild Cognitive Decline May be normal age related changes (Mild Cognitive Impairment or MCI) Individuals may notice memory lapses in terms of forgetting words, names, where they Stage 3 – Mild Cognitive Decline Friends, family or coworkers may start to notice memory issues. Word finding or memory difficulties may become apparent on clinical testing. Occupational tasks may suffer from inability to remember steps Difficulty remembering names of new people Problems with retaining read material Loss of ability to plan Losing of valuables Stage 4 – Moderate Cognitive Decline Decreased knowledge of current events Loss of ability to perform mental arithmetic or handle change Inability to perform complex tasks such Loss of memory of personal history Withdrawl in complex or socially challenging situations Less likely to enjoy gatherings or crowds Stage 5 – Moderately Severe Cognitive Decline Major cognitive gaps emerge. Patients require assistance with day to day activities such as choosing clothing Cannot recall important details Confusion about where they are or about time such as date Retain strong sense of self and autonomy Recognize familiar individuals such as Stage 6 – Severe Cognitive Decline Personality changes emerge Require assistance with basic activities of daily living such as bathing or using the toilet – often incontinent Lose awareness of recent experiences and surroundings Forget names of familiar people but can usually distinguish faces Disruptions in normal sleep/wake cycles May be delusional, hallucinate, be paranoid Wander and become lost easily Stage 7 – Very Severe Cognitive Decline Cannot respond to environment or stimuli Cannot control own body, lose ambulatory ability and are bed bound Cannot speak recognizably with Cannot eat without assistance Reflexes become abnormal and muscles become rigid and contract Alzheimer’s Disease – The Cholinergic Hypothesis The neurons most destroyed by Alzheimer’s use acetylcholine as their primary neurotransmitter Difficult to directly raise levels of acetylcholine in the brain Indirect raising of levels by preventing breakdown into individual components more successful Acetylcholinesterase Inhibitors Block the enzyme that breaks acetylcholine down to component parts Four varieties: Cognex (tacrine) Aricept (donepezil) Exelon (rivastigmine) Razadyne (galantamine) Each has slightly different effects and side effects A New Idea: Fighting Cell Death The chemical glutamate involved in telling cells when to die Does so by activating receptors that speed up cell function (NMDA receptors) Blockage of this effect saves neurons and function How Glutamate Functions Memantine – A New Medication Different mechanism of action than previous May be used in conjunction with acetylcholinesterase inhibitors Active at later stages of disease Brand name Namenda Medications Proven Not To Work For Alzheimer’s Disease Gingko Biloba Vitamin C supplements Vitamin E supplements Other Medications: Treatment of Behavioral Symptoms Tranquilizers Sleep aids Antipsychotics Antidepressants Neural pathway inhibitors Tranquilizers Short acting benzodiazepines Ativan (lorazepam) Xanax (alprazolam) Long acting benzodiazepines Valium (diazepam) Konopin (clonazepam) Sleep Aids Desyrel (trazodone) Ambien (zolpidem) Lunesta (eszopiclone) Restoril (temazepam) Rozerem (ramelteon) Antipsychotics Risperdal (risperidone) Zyprexa (olanzapine) Geodon (ziprasidone) Abilify (aripriprazole) Seroquel (quetiapine) Haldol (haloperidol) Antidepressants SSRIs Prozac (fluoxetine) Zoloft (sertraline) Celexa (citalopram) Lexapro (escitalopram) Paxil (paroxetine) SNRIs Effexor (venlafaxine) Pristiq (desvenlafaxine) Cymbalta (duloxetine) Other Remeron (mirtazapine) Pamelor (nortriptyline) Neural Pathway Inhibitors Tegretol (carbemazepine) Depakote (valproic acid) Neurontin (gabapentin) Lyrica (pregabalin) The Next Step? Bapineuzumab Monoclonal antibody against amyloid plaques Some preliminary studies suggest ‘clearing’ of plaque possible Medications Proven Not To Work For Alzheimer’s Disease Gingko Biloba Vitamin C supplements Vitamin E supplements ?Prevagen Dementia Treatment: More Than Medication Dementia involves social context and family systems Dementia must be approached as a chronic illness The behavioral issues in dementia require behavioral interventions Dementia Treatment: A Model Functional life Disease Acute Treatment Dysfunction Functional Balance Restored Case Mgmt. Techniques Designing Environments Appropriate for reverse developmental stages Safe and secure Uphold autonomy and dignity wherever possible Take other conditions of aging such as visual or hearing problems into account Put the ‘home’ before the ‘nurse’ Environmental Needs Touch gardens and plants Generationally appropriate music Fresh air and sunshine Children Pets Sensory stimulation Art Behavioral Treatment Behavioral problems should be treated behaviorally, not medically Some behaviors are normal in dementia and need not be treated Caregivers and families need to educate themselves in what is normal and what requires intervention The Use of Hospice in Dementia Limited by Medicare rules to patients in FASS stage 7 or in rapid decline. In general, for patients who cannot walk, feed themselves or make their needs known verbally. Assistance to patients and family systems to cope with inevitable decline and death. Dementia: Some Uncomfortable Realities Dementia tends to be medicalized as strictly a brain disorder Dementia care regarded as a personal rather than a public responsibility Reductions in public funds available for elder programs The Over Medicalization of Dementia Emphasis on medication rather than behavioral modification The reliance on the nursing home as a provider Resistance to therapeutic modalities as ‘nonmedical’ Lack of interest from providers as ‘incurable’ The Problem of Medicare Medicare not designed for treatment of chronic diseases like dementia Most things needed by dementia patients outside of Medicare’s benefits Costs of long term care cannot be borne by Medicare with current design Social Disinterest in Dementia Scary to individuals on a very personal level Invisibility of dementia patients Competition for resources Youth oriented society Tilt of public away from social programs to private gain Societal Choices What should our policies be regarding dementia and Elder Care? How should we divide the necessary resources between public and private? These are not abstract notions – This is our future. 25-50% of us will have dementing illness before we die A Thought To Take Home When the problems are obvious, ask the obvious questions We are the system – nothing will change unless we want it to