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Magnetic Resonance Imaging for the F1 What is MRI? MR imaging is based on the naturally occurring magnetic moment that exists within the nuclei of a hydrogen atom. When an external magnetic field is applied the protons within hydrogen nuclei align themselves parallel to the field and begin to resonate. When a radiofrequency pulse is applied to these protons it provides enough energy to dislodge them from this orientation. This is a temporary phenomenon and the nuclei relax back into realignment with the external magnetic field. Upon relaxation, energy is released in the form of RF waves. This echo is detected and a signal of variable intensity for a given location is produced. The signal is picked up by special aerials called coils and sent to a computer for processing. The computer converts the radio signals into pictures which are displayed on the computer screen. The imaging produced forms ‘slices’ of the area being examined. Strengths and weaknesses of MRI Strengths Weaknesses Multi-planar capabilities Superior soft-tissue contrast No known side-effects Can be used in pregnancy Limited use for bony imaging Not ideal for patients with claustrophobia Expensive Time consuming. Patient must lie very still for a good image. Different types of MRI T1 is when they programme the machine to only look at the longitudinal movement of protons. T1 images are usually used to look at normal anatomical details. T2 is the transverse movement of protons and is usually used to look at pathology because most tissues involved in disease tend to have a higher water content than normal. Key points: - Anatomical MRI is T1 weighted. T1 is best for looking at brain structure because fat appears very bright and bone marrow contains a great deal of fat. - Functional MRI is T2 weighted. Water and fluid are brighter on T2- ideal for tissue oedema. - White matter appears a light grey in T1 and a dark grey in T2. - Grey matter appears grey in both. - Cerebrospinal fluid (CSF) appears black in T1 and white in T2. Indications for use (not an exhaustive list) Examples Brain Brain tumors Stroke Dementia Multiple sclerosis Motor neurone disease Brain infections Brain injury Alzheimer’s disease Parkinson’s disease Musculoskeletal Athritis Osteomyelitis Cartilage damage Tendon, muscle, ligaments (sports injuries) Repetitive strain injuries. Spinal injuries. Acute cord compression. Malignancies Breast cancer Prostate cancer Gynecological malignancies Rectal cancer Lymph nodes Metastases Orbits Exophthalmos Eye injuries Orbital tumour Liver Cirrhosis Abscesses Liver cancer Vascular Aneurysms Atherosclerosis Contraindications (any metallic foreign bodies) Internal (implanted) defibrillator or pacemaker. Cochlear (ear) implant. Surgical clips such as those used on brain aneurysms. Artificial heart valves. Implanted drug infusion ports. Implanted electronic device, including a cardiac pacemaker. Artificial limbs or metallic joints. Implanted nerve stimulators. Pins, screws, plates, stents or surgical staples.