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Insulin, Glucose and You Insulin and Glucose When you hear the word insulin, you may think of a drug taken by people who have diabetes. While this is true, what you may not know is that insulin is one of the many important hormones created in the human body. Insulin is important to the body. It allows blood sugar (or glucose) to get into cells to provide them with energy. When you eat, your body breaks down food into glucose in your small intestine. This is your body's source of energy for everything it does, from working and thinking to exercising and healing. Glucose travels through your bloodstream, looking for individual cells that need energy. For glucose to get into the cells, it requires insulin. Insulin is the key that unlocks cells for glucose to enter and deliver energy. When insulin arrives, it signals the cell to activate glucose transporters. These transporters pull glucose through cell walls. When glucose moves into the cell, it delivers energy! Insulin Deficiency Insulin is normally produced in the pancreas. When glucose enters your bloodstream, the pancreas matches it with the right amount of insulin to move glucose into your cells. In people with type 2 diabetes, the pancreas may not be doing its entire job. It may produce less and less insulin over time. If this happens, there isn't enough insulin in the bloodstream to unlock cells. With the cells locked, glucose can't get where it is needed to provide energy. Insulin Resistance In some type 2 diabetes patients, cells build up a resistance to insulin. Even though there may be enough insulin in the bloodstream, it can't unlock cells to allow glucose to enter. © 2002 - 2010 sanofi-aventis U.S. LLC. All rights reserved US.GLA.10.01.108 As a result, it takes more insulin to find the right key to unlock the cell for glucose. This makes it more difficult for cells to get the energy they need. The Effects of Diabetes When glucose can't get into cells either because there isn't enough insulin or because the body is resisting it glucose begins to build up in the bloodstream. As a result, all that energy is wasted. It does not get to cells where it is needed. Without glucose in your cells, they lack the energy they require to keep your body working. Share this video with your diabetes patients while discussing the benefits and risks of insulin. Insulin is indicated to help improve glycemic control in patients with diabetes mellitus. Insulin works as part of an overall diabetes treatment plan, which may include diet, exercise and other diabetes medications. Treatment plans and glycemic targets should be individualized for each patient. Important Safety Information About Insulin Possible side effects may include blood glucose levels that are too low, injection site reactions, and allergic reactions, including itching and rash. Other medications and supplements could change the way insulin works. Glucose monitoring is recommended for patients with diabetes. © 2002-2010 sanofi-aventis U.S. LLC. All rights reserved. Legal Disclaimer Information and Privacy Policy Questions or Comments? Click here to contact us. This site intended for use by US Healthcare Professionals Only. US.GLA.10.01.108 Last Update: January 2010 © 2002 - 2010 sanofi-aventis U.S. LLC. All rights reserved US.GLA.10.01.108