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The categories for today’s
Jeopardy on Substance Use
will be:
Opioids
Stimulants
Alcohol Use
Disorder
Criterion A
Substance
Induced
disorders
Opioids
Stimulants
100
100
100
100
100
200
200
200
200
200
300
300
300
300
300
400
400
400
400
400
500
500
500
500
500
600
600
600
600
600
700
700
700
700
700
800
800
800
800
800
900
900
900
900
900
Alcohol Use
Disorders
Subst Use
Disorders
Criterion A
Substance
Induced
Disorders
What is 12-36 hours?
Opioids can be detected thru a urine
drug test for this many hours after
administration of the opioid
Row 1, Col 1
What is hepatitis C?
This type of liver disease may occur
in up to 90% of persons who
inject opioids
1,2
What is bacterial endocarditis?
HIV, hepatitis, tuberculosis, and
this cardiac related condition
are serious medical problems
for IV opiate users
1,3
What is pupil dilation?
This physical sign of opiate
withdrawal is also “seen” in
hallucinogen intoxication and
stimulant intoxication
1,4
What is naloxone (narcan)?
Opioid intoxication may be diagnosed
by administering this opioid
antagonist challenge
1,5
What is piloerection & fever?
These two symptoms are associated
with more severe opiate
withdrawal and are often not seen
in routine clinical practice
1,6
What is naloxone (narcan) & buprenorphine?
Suboxone is a combination of these two
medications
1,7
What is lightneadedness?
Withdrawal: dysphoria, N/V, muscle aches,
lacrimation/rhinorrhea, pupil
dilation/piloerection, fever, sweating,
Yawning, insomnia, dizziness, diarrhea
This one is not part of opiate
withdrawal
1,8
What is slurred speech?
Signs of opioid intoxication are pupil
constriction, drowsiness/coma,
impaired attention or memory,
and this
1,9
What is a urine drug test?
(Clinical picture is similar though rotary nystagmus may be
seen in PCP intoxication but not stimulant)
This can differentiate PCP
intoxication & stimulant
intoxication from each other
2,1
What is alcohol?
Cocaine users often use sedative
substances--most often this
substance--to reduce insomnia,
nervousness, and other
unpleasant side effects
2,2
What is marijuana?
Amphetamine type stimulant users
often use sedative substances-most often this substance--to
reduce insomnia, nervousness,
and other unpleasant side effects
2,3
What is a bradycardia?
This sign is often present and is a
reliable measure of stimulant
withdrawal
2,4
What is antisocial personality disorder?
Bipolar disorder, schizophrenia, other
substance use disorders, and this
personality disorder in particular
are risk factors for stimulant use
disorder
2,5
What is a hair sample
This type of sample can be used to
detect use of a stimulant up to
90 days after the use
2,6
What is inhalation and injection?
These two forms of cocaine
administration have the most
rapid onset of action
2,7
What is heroin?
A speedball is the combination of
cocaine and this drug
2,8
What is dopamine?
Cocaine increases the levels of
glutamate and this
neurotransmitter
2,9
What is positive reinforcement?
In terms of operant conditioning, the
alcohol induced buzz/high is this;
also tolerance results in the
lack of this
3,1
What is negative reinforcement?
In terms of operant conditioning,
consuming alcohol to stave off
alcohol withdrawal symptoms
results in this
3,2
What is 1 month?
(Most improve within days to weeks of abstinence)
Most substance induced disorders resolve
within this amount of time after the cessation
of acute withdrawal, the cessation of severe
intoxication, or the use of the substance.
3,3
What is males?
Males ~12%, Females ~5%
The prevalence of alcohol use disorder
in this sex is twice as much as
the other
3,4
What are 3-4 times?
For an individual who has a close
relative (parent) with an alcohol use
disorder, their risk is this many times
higher than normal
3,5
What is Asians?
Japanese, Chinese, and Koreans are at lower risk for
Alcohol Use Disorders
Alcohol metabolizing enzyme genetic
polymorphisms result in flushing,
palpitations, & possibly more
severe reactions in individuals
of this race when they
consume alcohol
3,6
What is gamma-glutamyltransferase (GGT) and carbohydratedeficient transferrin (CDT)?
Elevations in these two lab test results
are sensitive indicators of ongoing
heavy drinking and can be used to
monitor abstinence
3,7
What is mean corpuscular volume (MCV)?
Not useful for monitoring due to long half life of RBC’s
While elevation of GGT, CDT, and
this test indicates a history of heavy
drinking, GGT & CDT test may also
be useful in detecting a relapse
to heavy drinking, but
this test is not
3,8
What is Antisocial Personality Disorder?
The patients with bipolar disorder,
schizophrenia, & this personality
disorder have a markedly high
rate of co-morbid alcohol
use disorder
3,9
What is brain circuitry?
Substance use disorder pts, especially
those with severe disorder, have an
underlying change in this which
persists even beyond detoxification
4,1
What is social impairment?
Impaired control, Social impairment,
Risky use, or Pharmacological criteria
Continued use despite persistent or
recurring interpersonal problems
4,2
What is impaired control?
Impaired control, Social impairment,
Risky use, or Pharmacological criteria
A desire to cut down or unsuccessful
attempts decrease or stop use refers
to this Criterion A
4,3
What is tolerance & withdrawal?
Impaired control, Social impairment,
Risky use, or Pharmacological criteria
Pharmacological criteria refers to
“putting up” with these two
phenomenon
4,4
What is impaired control?
Impaired control, Social impairment,
Risky use, or Pharmacological criteria
Taking the substance in larger
amounts or over a longer time
period than intended refers to this
Criterion A
4,5
What is risky use?
.
Impaired control, Social impairment,
Risky use, or Pharmacological criteria
Use in physically hazardous situations or
continued use despite knowledge the
substance is causing or worsening a
medical problem is called this
4,6
What is impaired control?
Impaired control, Social impairment,
Risky use, or Pharmacological criteria
Spending a great deal of time obtaining,
using, or recovering from the substance
use refers to this Criterion A
4,7
What is social impairment
Impaired control, Social impairment,
Risky use, or Pharmacological criteria
Failure to fulfill major obligations at
work, home, or school refers to this
Criterion A
4,8
What is impaired control?
Impaired control, Social impairment,
Risky use, or Pharmacological criteria
Craving refers to this Criterion A
4,9
What is anxiety?
Caffeine intoxication may induce a
sleep disorder or this type of
substance induced disorder
5,1
What is Psychotic disorder?
Marijuana intoxication may induce
anxiety disorders, sleep disorders,
and this type of substance
induced disorder
5,2
What are mood disorders?
(both bipolar & depressive)
The hallucinogen phencyclidine
may induce psychotic disorders,
anxiety disorders, delirium,
& this type of substance
induced disorders
5,3
What is depressive disorders?
Opioid intoxication may induce sleep
disorders, sexual dysfunction,
delirium, & this type of
substance induced disorder
5,4
What are anxiety?
Opioid intoxication will not, but
opioid withdrawal may induce this
type of substance disorder
5,5
What is anxiety?
Psychotic, Bipolar, Depressive, Sleep, Sexual
Dysfunction, Delirium, Neurocognitive disorders
Alcohol & sedative/hypnotic
intoxication may both induce the
same type of substance disorders
except sedative/hypnotic
intoxication will NOT
induce this
5,6
What are psychotic disorders?
Intoxication, but not withdrawal,
of stimulants such as cocaine may
induce sexual dysfunction, delirium
& this type of substance
induced disorder
5,7
What is mood?
(both bipolar & depressive)
Intoxication & withdrawal of
stimulants such as cocaine may
induce, anxiety, OCD, sleep, & this
type of substance induced disorder
5,8
What is hallucinogens?
Inhalants and this type of substance
do not cause a withdrawal
5,9