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Functional anatomy of alimentary (digestive) system Alimentary system is a collection of organs which provide mechanical and chemical digestion of food, absorption of nutrients into blood and lymph and excretion of feces Alimentary system organs Oral cavity Pharynx Oesophagus Liver Stomach Pancreas Small intestine Large intestine Parts of small intestine Duodenum Jejunum Ileum Parts of large intestine Transverse colon Ascending colon Descending colon Caecum Sigmoid colon Rectum mouth anus fauces I II III IV V VI Lingual papillae Taste sensation of tongue Parotid gland Sublingual gland Submandibular gland Parodontium includes: periodontal fibres, jawbone, gum and dental root Permanent teeth 2.1.2.3 Deciduous teeth 2.1.0.2 Upper right quadrant Upper left quadrant Lower right quadrant Lower left quadrant Total length of digestive tract is about 10 m Pharynx (12-15 cm) Oesophagus (25-30 cm) Small intestine (6 – 7 m) Large intestine (1,5 – 2 m) VI cervical vertebra X-XI thoracic vertebra I lumbar vertebra Epigastrium Mesogastrium Hypogastrium The digestive organs Hollow Parenchymatous 1.Pharynx; 2.Oesophagus; 3.Stomach; 4.Small intestine; 5.Large intestine 6. Gallbladder 1.Salivary glands; 2.Liver; 3.Pancreas Hollow Other organs Parenchymatous 1.Urinary bladder; 1.Spleen; 2.Uterus; 2.Lungs; 3.Ureter; 3.Testes; 4.Deferent duct; 4.Prostate 5.Uterine tube 5.Endocrine glands Structure of hollow organs Serous layer Muscular layer Mucous layer Structure of hollow organs Mucous layer Muscular layer Serous (or adventitial) layer Structure of mucosa Epithelium Lymphatic follicle Lamina propria Lamina muscularis Submucous layer Glands Oral mucosa Gastric mucosa Gastric pits Simple columnar epithelium Intestinal mucosa Villus Simple columnar epithelium Mucosa of colon Crypt Simple columnar epithelium Muscular layer in oesophagus Circular layer Longitudinal layer Muscular layer in stomach Muscular layer in small intestine Muscular layer in large intestine Haustra Taenia Cardiac (lower oesophageal) sphincter ileocaecal valve ileocaecal orifice Visceral peritoneum Greater omentum Parietal peritoneum Retroperitoneal space Mesentery Peritoneal cavity Relatively to the peritoneum the organs can be divided into: Intraperitoneal Mesoperitoneal Extraperitoneal Intraperitoneal organs 1.Stomach 5. Caecum with appendix 2.Spleen 6. Transverse colon 3.Jejunum 7. Sigmoid colon 4.Ileum 8. Upper rectum Mesoperitoneal organs 1.Liver 5. Uterus 2.Gallbladder 6. Full urinary bladder 3.Ascending colon 8. Middle rectum 4.Descending colon Extraperitoneal organs 1.Pancreas 4. Empty urinary bladder 2.Duodenum 5. Kidneys 3.Lower rectum 6. Suprarenal glands Structure of hollow organs Serous (or adventitial) Muscular layer layer Mucous layer Structure of parenchymatous organs - consist of glandular tissue - have no lumen inside The smallest parts of the parenchymatous organs, bounded by connective-tissue frame and surrounded by their own blood stream, are called structural and functional units. In the liver the structural and functional unit is hepatic lobule In the pancreas the structural and functional unit is pancreatic acinus Liver segmentation I Caudate lobe II Superolateral segment of left lobe III Inferolateral segment of left lobe IV Medial segment of right lobe V Anteroinferior segment of right lobe VI Posteroinferior segment of right lobe VII Posterosuperior segment of right lobe VII Anterosuperior segment of right lobe Development of digestive system: stage of 20 days Development of digestive system: stage of 20 days neural tube chorda celom mesoderm ectoderm entoderm Derivatives of ectoderm 1. enamel 2. salivary glands ectoderm Derivatives of ectoderm 1. epithelium 2. glands (liver, pancreas) entoderm (primitive gut) Derivatives of mesoderm splanchnopleura 1. mucosa 2. submucous layer 3. muscular layer 4. serous layer (visceral peritoneum) splanchnopleura Derivatives of mesoderm somatopleura somatopleura parietal peritoneum Development of digestive system: stage of 30 days pharynx oesophagus stomodeum stomach yolk stalk allantois liver midgut proctodeum cloaca hindgut Development of digestive system: stage of 35 days cerebral and neural tubes chorda trachea oesophagus stomach liver midgut coelom (peritoneal cavity) hindgut heart allantois yolk stalk cloaca rectum Division of the primitive gut into the parts Foregut descending limb Midgut umbilical (yolk) loop Hindgut ascending limb Division of the primitive gut into the parts Foregut Midgut Hindgut Oesophagus, stomach, descending part of duodenum Small intestine (from descending limb); Caecum,ascending colon, transverse colon (from descending limb) Descending colon, sigmoid colon rectum Development of mesenteries stomach liver spleen ventral mesentery pancreas Falciform ligament Hepatogastric ligament Hepatoduodenal ligament dorsal mesentery Greater omentum Mesentery of small intestine Sigmoid mesocolon The twist of gut tube: stage of 5 weeks I branchial arch -the walls of the oral cavity (including maxilla and mandible) -lips - masticatory muscles II branchial arch -hyoid bone - mimic muscles