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Planning Assignment (3 field rectum) Use a CT dataset of the pelvis. Create a CTV by contouring the rectum (start at the anus and stop at the turn where it meets the sigmoid colon). Expand this structure by 1 cm and label it PTV. Create a PA field with the top border at the bottom of L5 and the bottom border 2 cm below the PTV. The lateral borders of the PA field should extend 1-2 cm beyond the pelvic inlet to include primary surrounding lymph nodes. Place the beam isocenter in the center of the PTV and use the lowest beam energy available (note: calculation point will be at isocenter). Contour all critical structures (organs at risk) in the treatment area. List all organs at risk (OR) and desired objectives/dose limitations, in the table below: Organ at risk Bladder Desired objective(s) D45Gy<15% Achieved objective(s) D45Gy<15% Femoral heads and necks <45Gy, Preferred <40Gy <43.5Gy Bowel <50Gy, Preferred <5Gy <44Gy *Achieved objectives values obtained from final 4 Beam plan. a. Enter the prescription: 45 Gy at 1.8 /fx (95% of the prescribed dose to cover the PTV). Calculate the single PA beam. Evaluate the isodose distribution as it relates to CTV and PTV coverage. Also where is/are the hot spot(s)? Describe the isodose distribution, if a screen shot is helpful to show this, you may include it. A. This planning assignment begins with a 1 beam posterior to anterior field targeting the rectum with a +1 cm expanded margin as the PTV (red color shade). The energy of the beam is set at 6MV and the resulting isodose distribution results in a shape somewhat like a square with the highest dose/hot spots located superficially on the posterior side. As the dose goes further into the body, the hotter isodose lines fall off one by one. b. Change to a higher energy and calculate the beam. How did your isodose distribution change? B. This step of the assignment the energy of the beam is increased to 15MV and the isodose lines changed significantly for the better. The overall square shape of the distribution stayed the same, however the dose has pushed deeper into the body. Using the higher energy is better for this case since the PTV was only partially covered with the lower 6MV energy beam used in part A. The higher energy beams deeper penetrating ability also reduced the hot spots on the superficial posterior part of the body. c. Insert a left lateral beam with a 1 cm margin around the ant and post wall of the PTV. Keep the superior and inferior borders of the lateral field the same as the PA beam. Copy and oppose the left lateral beam to create a right lateral field. Use the lowest beam energy available for all 3 fields. Calculate the dose and apply equal weighting to all 3 beams. Describe this dose distribution. C. A 3 field beam arrangement was used for this part of the assignment. The original PA beam was kept intact and 2 lateral beams were added to the plan. All 3 beam energies were set to 6MV and were all given equal weight distribution. Adding the 2 lateral beams to the plan created more of a flattening effect to the isodose distribution while also increasing the dose to the lateral superficial portions of the body. Compared to step B, this 3 field lower energy beam plan would be unfavorable. d. Change the 2 lateral fields to a higher energy and calculate. How did this change the dose distribution? D. By increasing the energy of the lateral beams to 15MV, the dose to the skin on the lateral borders was reduced significantly. The flattening effect from originally adding the 2 lateral beams however was minimally reduced. e. Increase the energy of the PA beam and calculate. What change do you see? E. Increased the PA beam to a higher energy so now all 3 beam fields are set to 15MV. The shape of the isodose distribution stayed the same, but decreased the hot spots on the posterior superficial border significantly. f. Add the lowest angle wedge to the two lateral beams. What direction did you place the wedge and why? How did it affect your isodose distribution? (To describe the wedge orientation you may draw a picture, provide a screen shot, or describe it in relation to the patient. (e.g., Heel towards anterior of patient, heel towards head of patient..) F. Added small 10 degree angle wedges to the lateral beams. The orientation of the wedges are placed with the heels posterior to the patient. I chose to place the wedges in this orientation because of the hot spots on the posterior corners of the isodose distribution. The wedges did exactly what I had hoped by reducing the dose to these areas. g. Continue to add thicker wedges on both lateral beams and calculate for each wedge angle you try (when you replace a wedge on the left, replace it with the same wedge angle on the right) . What wedge angles did you use and how did it affect the isodose distribution? G. This step of the process I changed the thickness of the wedges used for the lateral beams. I evaluated the dose distributions for wedge angles of 30 degrees, 45 degrees, and 25 degrees. As a side note, all of the comparisons were with the heel of the wedges posterior to the patient. When comparing the 30 degree wedge angles to the 10 degree angles for step F, the PTV coverage had better, steeper dose drop off with the 30 degree angle and the hot spots were reduced on the posterior superficial border. There was a slight increase in dose to the lateral borders near the femurs however the better isodose distribution for the PTV makes this wedge angle better than the 10 degree angle. The next comparison I did was with the steeper 45 degree angle wedges. Since this was quite a steep angle of wedge, the dose concentration had shifted with the hotter areas previously on the posterior border to the anterior portion of the isodose distribution. The dose to the femurs and lateral borders increased even more than it did with the 30 degree angle wedges thus making this wedge angle not a preferred choice for the plan. The final wedge angle I compared was the 25 degree wedge. This wedge helped reduce the hot spots on the posterior superficial border while minimizing the increased dose to the lateral borders/femurs that the steeper wedge angles resulted in. The DVH also showed better PTV coverage and dose drop off than the other wedge combinations. h. Now that you have seen the effect of the different components, begin to adjust the weighting of the fields. At this point determine which energy you want to use for each of the fields. If wedges will be used, determine which wedge angle you like and the final weighting for each of the 3 fields. Don’t forget to evaluate this in every slice throughout your planning volume. Discuss your plan with your preceptor and adjust it based on their input. Explain how you arrived at your final plan. H. My final 3 field plan I chose utilized 15MV energy for all three beams and 45 degree wedges on the lateral beams. The dose weighting was adjusted to 41% for the PA beam and 29.5% for each of the lateral beams. This beam weighting combination pulled the dose away from the lateral borders/femurs while keeping the hot spots as low as possible on the posterior superficial border. *It is important to note that these plans were not utilizing blocking or MLCs as were not instructed to do so. i. In addition to the answers to each of the questions in this assignment, turn in a copy of your final plan with the isodose distributions in the axial, sagittal and coronal views. Include a final DVH. Final 3 beam image: DVH of final 3 beam plan and 4 beam plan: 4 field pelvis Using the final 3 field rectum plan, copy and oppose the PA field to create an AP field. Keep the lateral field arrangement. Remove any wedges that may have been used. Calculate the four fields and weight them equally. How does this change the isodose distribution? What do you see as possible advantages or potential disadvantages of adding the fourth field? By using a 4 field (box) plan, the isodose distribution becomes more of a box in shape. The dose to the superficial parts of the body are brought in more tightly than they are with the 3 field plan. The advantages of using a 4 field plan is the dose is more tightly compacted into the treatment target thus reducing the dose to the farther outlying structures such as the dose to the femurs. By using an evenly weighted 4 field box, the plan is debatably simpler in design since the comparable 3 field plan has to incorporate wedges and changes in beam weighting in order to match the efficiency of 4 fields. The disadvantages of using a 4 field (box) plan is the higher dose to structures closer to the target PTV. Such as the dose to the prostate, bladder, and small bowel, there is a much higher dose to these structures when compared to the 3 field plan. The hot spots were very similar when comparing both plans so the decision of choosing a 3 field or 4 field plan would be determined by which structures the doctor wishes to reduce the dose for. Both methods result in excellent PTV coverage for structures of the pelvis. Image 4 beam arrangement: