Download View Dhiraj Gupta`s Resume / CV

Dr Dhiraj Gupta
MBBS, MD, DM, FRCP (UK)
Date of Birth
08 October 1970
Sex
Male
Nationality
British
Telephone
01516001793 (Office)
Email
[email protected]
GMC
5205561 (Full Registration)
Current Appointments
March 2007 till date
Consultant Cardiologist / Electrophysiologist
The Liverpool Heart and Chest Hospital
July 2011 till date
Honorary Senior Lecturer, Imperial College, London
June 2012 till date
Clinical Lead and Co-founder, Primary Care AF service
Nov 2014 till date
Medical Advisor, Atrial Fibrillation Association UK
Aug 2015 till date
Head, Arrhythmia Working Group, ICMS
Oct 2015 till date
Member of Council, British Heart Rhythm Society
Nov 2015 till date
Honorary Senior Lecturer, University of Liverpool
Oct 2014 till date
Member of Scientific Program Committee, HRC
Brief Profile
I am a consultant cardiologist/ electrophysiologist at the Liverpool Heart and Chest Hospital
(LHCH) since 2007. LHCH provides a regional electrophysiology (EP) service to a
population of 2.8 million, and is the largest cardiac centre in the United Kingdom. I am a very
high volume operator in interventional EP, and have performed over 200 ablation cases
annually since 2009. I am the trust lead for Left Atrial Appendage Occluder Service, and our
hospital is one of 10 sites selected nationally by the NHS England as part of the
Commissioning through Evaluation (CtE) program. I have been awarded NHS Clinical
Excellence Awards in 2010, 2014 and 2015.
I have earned repute for my expertise in treating patients suffering from Atrial Fibrillation
(AF), and I work closely with the British Heart Foundation to provide education and training
to their staff nationally. I am also member of the Medical Advisory Committee of the national
charity, AF Association.
I have held the position of Honorary Senior Lecturer at Imperial College London since 2011.
I am the primary supervisor for two MD (res) students at Imperial, and also assess the
progress of other Imperial Students working towards higher research degrees. I have also
examined PhD and MD (res) candidates for Queen Mary University London.
Dhiraj Gupta
Dec 2015
I am the Chief Investigator for three multi-centre trials (PRESSURE, SMANPAF, and
PRAISE), and have been successful in obtaining over £1.5 million in competitive research
grants.
In addition to my roles as an interventional EP cardiologist and researcher, I have forged
strong links with primary care. In 2012 I designed and developed the Primary Care Atrial
Fibrillation (PCAF) service to improve stroke prevention, and this service has won several
national awards for innovation and impact.
I have been elected to the Council of British Heart Rhythm Society in Oct 2015 for a term of
three years, and as a council member I help shape national guidelines and policies related to
arrhythmia care.
Awards and Honours
October 2014: Arrhythmia Alliance Excellence in Practice Award for ‘Outstanding
Individual who has contributed to Arrhythmia Services in the United Kingdom’ awarded at
Heart Rhythm Congress, Birmingham
October 2014: My research fellow won the Young Investigator Award in the clinical category
at the Heart Rhythm Congress, Birmingham
Sep 2014: PCAF service won the Quality in Care winner of the ‘Anticoagulation Innovation
of the Year Award’ at British Medical Association House, London
June 2014: PCAF service was the winner of the ‘Innovation in Cardiac Pathways’
competition at the British Cardiac Society Sessions, Manchester
June 2013: My research fellow won the Highest Ranking abstract in the Heart Rhythm
Category at the British Cardiac Society Sessions, London
Nov 2014: I have been invited to speak at the All Parliamentary Group on Atrial Fibrillation
meeting at Westminster to share our experiences of engaging with primary care through the
PCAF service
Previous Appointments
Oct 2004- Feb 07
Clinical Fellow in Electrophysiology
St. Bartholomews Hospital, West Smithfield, London
Oct ’03 –Sep ’04
Specialist Registrar in Cardiology
St. Bartholomews Hospital, West Smithfield, London
Jan ’03-Sep ’03
Specialist Registrar in Cardiology
Royal London Hospital, Whitechapel, London
Oct ’01- Dec ’02
Specialist Registrar in Cardiology
London Chest Hospital, London
Oct ’00-Sep ’01
Clinical fellow in cardiac electrophysiology
St. George’s Hospital Medical School, London
July ’97- Jun ’00
Registrar in cardiology and DM fellow
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Dhiraj Gupta
Dec 2015
All India Institute of Medical Sciences, New Delhi
July ’94- Jun ’97
Senior House Officer, Internal Medicine & MD fellow
Post Graduate Institute of Medical Education &
Research, Chandigarh, India
Academic Qualifications
April 1994
MB BS (Bachelor of Medicine and Bachelor of Surgery)
Moti Lal Nehru Medical College, Allahabad, India
June 1997
MD (Doctor of Medicine) in Internal Medicine
Post Graduate Institute of Medical Education & Research, Chandigarh,
India
June 2000
DM (Doctorate in Medicine) in Cardiology
All India Institute of Medical Sciences, New Delhi, India
July 2001
MRCP (UK) Royal College of Physicians, London
October 2006
CCT (Cardiology)
Joint Committee for Higher Medical Training (JCHMT), UK
May 2012
FRCP (UK) Royal College of Physicians, London
Research Supervision, Review and Examiner Roles
July 2013-current: Imperial College, London – Primary Supervisor for MD (res) Dr M Das
Jul 2011–Jun 2013: Imperial College, London –Primary Supervisor for MD (res) Dr G Wynn
2011-13: Supervision of 5 Nuffield Bursary Students
2012-14: Early and Late Stage Review for Imperial College, London-PhD Dr S Panniker
2015: External Examiner for PhD for Queen Mary University, London. Dr W Ullah
Competitive Grants Obtained
2015 $385,950 from IIS, Biosense Webster, CA, USA for ‘Pulmonary Vein Reconnection
Following Ablation Index-Guided Ablation: a Success Evaluation (PRAISE)’, IIS-385
2014 £1.24 million from NIHR, Awarded for the two-centre Catheter ablation and Surgical
ablation for Atrial Fibrillation (CASA AF trial), with Dr Tom Wong as the Chief Investigator
2014 £36,500 from IIS, Biosense Webster, CA, USA for The value of Ablation index to
predict sites of acute Pulmonary Vein Reconnection following ablation for Atrial Fibrillation:
Chief Investigator
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Dhiraj Gupta
Dec 2015
2013 £260,280 from IIS, Biosense Webster, CA, USA for PRESSURE study (IIS-239), as
Chief Investigator
2013 £50,000 from Sir Halley Stewart Trust, for appointment of Patient Centred
Arrhythmia Research Nurse
2013 £4985 for LHCH Pump Priming fund: “Patient Controlled Analgesia in PVI:
feasibility study”
2012 till date £30 000 per year from Biosense Webster Educational Grant UKEG00328, for
LHCH EP clinical fellow
Full Publications
1. M Das, L Panter, G Wynn, N Connor, J Mills, P Kirchhof, D Gupta. Primary Care
Atrial Fibrillation (PCAF) Service: Outcomes from Consultant-led anticoagulation
assessment clinics in the Primary Care setting. BMJ Open 2015;5:e009267
doi:10.1136/bmjopen-2015-009267
2. GJ Wynn, S Panniker, MCS Hall, RL Snowdon. JEP Waktare, V Markides, W
Hussain, J Jarman, DM Todd, T Wong, D Gupta. Biatrial linear ablation in sustained
non-permanent AF: Results of the Substrate Modification with Ablation and
antiarrhythmic drugs in Non-Permanent Atrial Fibrillation Trial. Heart Rhythm
doi:10.1016/j.hrthm.2015.10.006
3.
M Das, GJ Wynn, M Morgan, B Lodge, JEP Waktare, DM Todd, MCS Hall, RL
Snowdon, S Modi, D Gupta. Recurrence of Atrial Tachyarrhythmia during the
Second Month of the Blanking Period Predicts More Extensive Pulmonary Vein
Reconnection at Repeat Electrophysiology Study. Circ Arrhythm Electrophysiol 2015:
8: 846-52
4. GJ Wynn, M Das, LJ Bonnett, MCS Hall, RL Snowdon. JEP Waktare, S Modi, DM
Todd, D Gupta. A novel marker to predict early recurrence after atrial fibrillation
ablation: The Ablation Effectiveness Quotient. J Cardiovasc Electrophysiol 2015; 26:
397-403
5. Cardiac Arrest in athletes and resuscitation. PB Bapat, A Bapat, D Gupta. J Intensive
Care Soc 2015; 16: 85-86
6. Relationship between Contact Force Sensing Technology and Medium Term
Outcome of Atrial Fibrillation Ablation: A Multicenter Study of 600 Patients. Jarman
JW, Panikker S, Das M, Wynn GJ, Ullah W, Kontogeorgis A, Haldar SK, Patel PJ,
Hussain WJ, Markides V, Gupta D, Schilling RJ, Wong T. J Cardiovasc
Electrophysiol 2015; 26: 378-84
7. Wynn GJ, Das M, Bonnett LJ, Gupta D. Quality-of-life benefits of catheter ablation
of persistent atrial fibrillation: a reanalysis of data from the SARA study. Europace.
2015;17: 222-4
8. Wynn GJ, Das M, Bonnett LJ, Panikker S, Wong T, Gupta D. Efficacy of Catheter
Ablation for Persistent Atrial Fibrillation: A Systematic Review and Meta-Analysis
of Evidence from Randomised and Non-Randomised Controlled Trials. Circ
Arrhythm Electrophysiol. 2014; 7: 841-52
9. GJ Wynn, I Haq, J Hung, LJ Bonnett, G Lewis, M Webber, JEP Waktare, S Modi,
RL Snowdon, MCS Hall, DM Todd, D Gupta. Improving safety in catheter ablation
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Dhiraj Gupta
Dec 2015
for atrial fibrillation: a prospective study of the use of ultrasound to guide vascular
access. J Cardiovasc Electrophysiol. 2014; 25(7): 680-5
10. GJ Wynn, DM Todd, M Webber, LJ Bonnett, J McShane, P Kirchhof, D Gupta. The
European Heart Rhythm Association Symptom Classification for Atrial Fibrillation:
Validation and Improvement through a Simple Modification. Europace
2014;16(7):965-72
11. Wynn GJ, Das M, Gupta D. Re: Caution over use of catheter ablation for atrial
fibrillation. BMJ 2013. http://www.bmj.com/content/347/bmj.f5277/rr/662301
12. Haldar S, Jarman JWE, Panikker S, Jones DG, Salukhe T, Gupta D, Wynn G,
Hussain W, Markides V, Wong T. Contact force sensing technology identifies sites of
inadequate contact and reduces acute pulmonary vein reconnection: A prospective
case control study. Int J Cardiol 2013;168: 1160-6
13. R Liew, V Baker, L Richmond, K Rajappan, D Gupta, M Finlay, G Thomas, S
Harris, M Earley, S Sporton, R Schilling. A randomised controlled trial of
conventional catheter ablation with a novel minimal catheter approach for regular
supraventricular tachycardia. Europace 2009; 11(8):1057-64
14. Showkathali R, Earley MJ, Gupta D, Alzetani M, Harris S, Kistler PM, Sporton SC,
Schilling RJ. Current case mix and results of catheter ablation of regular
supraventricular tachycardia: are we giving unrealistic expectations to patients?
Europace 2007;9(11):1064-1068
15. Liew R, Rajappan K, Gupta D, Kistler P, Schilling R. Percutaneous epicardial
ablation reverses ventricular tachycardia mediated cardiomyopathy. J Interv Card
Electrophysiol. 2007;18(3):265-7
16. D Gupta, RK Al-Lamee, MJ Earley, PM Kistler, SJ Harris, AW Nathan, SC Sporton,
RJ Schilling. Cryoablation compared with radiofrequency ablation for atrioventricular
nodal reentrant tachycardia: analysis of factors contributing to acute and follow up
outcome. Europace. 2006;8(12):1022-6
17. D Gupta, MJ Earley, GA Haywood, L Richmond, M Haywood, P Kojodjojo, SC
Sporton, NS Peters, P Broadhurst, RJ Schilling Can atrial fibrillation with a coarse
electrocardiographic appearance be treated with catheter ablation of the tricuspid
valve-inferior vena cava isthmus? Heart. 2007;93(6):688-93
18. PM Kistler, K Rajappan, D Gupta, M Jahangir, MJ Earley, S Harris, D Abrams, R
Liew, S Ellis, SC Sporton. RJ Schilling. The impact of CT integration into an
electroanatomic mapping system on clinical outcomes of atrial fibrillation. J
Cardiovasc Electrophysiol. 2006;17(10):1093-101
19. MJ Earley, R Showkathali, M Alzetani, PM Kistler, D Gupta, DJ Abrams, JA
Horrocks , SJ Harris, SC Sporton, RJ Schilling. Radiofrequency ablation of
arrhythmias guided by non-fluoroscopic catheter location: a prospective randomized
trial. Eur Heart J. 2006;27(10):1223-9.
20. S Vallapuri, D Gupta, KK Talwar, M Billie, MC Mehta, AP Morise, A Jain.
Comparison of atherosclerotic risk factors in Asian Indian and American caucasian
patients with angiographic coronary artery disease. Am J Cardiol 2002; 90: 11471150
21. D Gupta, A Saxena, SS Kothari, R Juneja. Factors influencing late course of residual
valvular and infundibular gradients following pulmonary valve balloon dilatation. Int
J Cardiol 2001; 79 (2-3): 143-9.
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Dhiraj Gupta
Dec 2015
22. D Gupta, A Saxena, SS Kothari, R Juneja, M Rajani, S Sharma, P Venugopal.
Detection of coronary anomalies in Tetralogy of Fallot using a specific angiographic
protocol. Am J Cardiol 2001; 87: 241-44.
23. D Gupta, Kothari SS, Bahl VK, Goswami KC, Talwar KK, Manchanda SC,
Venugopal P. Thrombolytic therapy for prosthetic valve thrombosis: short and long
term results. Am Heart J 2000; 140 (6): 906-16.
24. D Gupta, Chawla YK, Dhiman RK, Suri S, Dilawari JB. Clinical significance of
patent paraumbilical vein in patients with liver cirrhosis. Digestive Diseases and
Sciences 2000; 45(9): 1861-4.
RECENT CONFERENCE ABSTRACTS (PAST 12 MONTHS ONLY)
1. GJ Wynn, S Panikker, M Morgan, M Hall, J Waktare, V Markides, W Hussain, TV
Salukhe, S Modi, MBBS, JWE. Jarman, DG. Jones, RL Snowdon, D Todd, T Wong, D
Gupta. Effect of linear ablation in substrate-based AF: Results of the Substrate
Modification with Ablation and antiarrhythmic drugs in Non-Permanent Atrial
Fibrillation Trial. Heart Rhythm 2015:12;1715
2. Das M, Wynn GJ, Morgan M, Lodge B, Waktare JEP, Todd DM, Hall MCS, Snowdon
RL, Modi S, Gupta D. Re-ablated sites of acute reconnection after pulmonary vein
isolation do not predict sites of late reconnection at repeat electrophysiology study. Heart
Rhythm 2015, 12(5S):S121.
3. Das M, Wynn GJ, Morgan M, Lodge B, Waktare JEP, Todd DM, Hall MCS, Snowdon
RL, Modi S, Gupta D. Ablation Index predicts sites of reconnection at repeat
electrophysiology study following pulmonary vein isolation. Heart Rhythm 2015,
12(5S):S362.
4. M Das, M Duytschaever, D Gupta, P Lukac, J Sorrel, T Phlips, AS Jadidi, H Nakagawa
Ablation Index Predicts Sites of Acute Reconnection after Pulmonary Vein Isolation
(PVI): a Multi-Center Retrospective Analysis. Heart Rhythm 2015, 12(5S):S86
5. Das M, Piddock N, Wynn GJ, Morgan M, Lodge B, Waktare JEP, Todd DM, Hall MCS,
Snowdon RL, Modi S, Gupta D. Low impedance drop predicts sites of acute
reconnection following pulmonary vein isolation. Heart Rhythm 2015, 12(5S):S445
6. Das M, Wynn GJ, Lodge B, Morgan M, Modi SS, Hall MCS, Snowdon RL, Todd DM,
Gupta D. Automated ablation lesion tagging with an integrated radiofrequency parameter
index predicts sites of acute reconnection following pulmonary vein isolation. Europace
2014, 16:iii17.
7. Das M, Panter L, Connor N, Mills J, Gupta D. The primary care atrial fibrillation (PCAF)
service: consultant-led anticoagulation assessment clinics in the primary care setting
increase the uptake of anticoagulation therapy in AF patients at high-risk of stroke.
Europace 2014, 16:iii16.
8. Das M, Wynn GJ, Khalatabari A, Cooke C, Morgan M, Lodge B, Gupta D.
Echocardiographic parameters of atrial conduction delay correlate to signal-averaged P
wave duration and predict AF recurrence in patients with sustained paroxysmal and
persistent AF. Europace 2014, 16:iii19.
9. Wynn GJ, Das M, Lodge B, Morgan M, Todd DM, Waktare JEP, Modi S, Gupta D,
McKevith JM. PCA for PVI: First report of successful use of patient controlled analgesia
for AF ablation. Europace 2014, 16:iii23.
10. Wynn GJ, Das M, Bonnett LJ, Webber M, Cabrera S, Modi SS, Snowdon RL, Hall MCS,
Waktare JEPW, Todd DM, Gupta D. A novel marker of success in atrial fibrillation
ablation: the Ablation Effectiveness Quotient (AEQ). Europace 2014, 16:ii136.
11. Lodge B, Wynn GJ, Das M, Cabrera S, Webber M, Morgan M, Gupta D, Todd DM. Age
and quality of life in catheter ablation of atrial fibrillation. Europace 2014, 16:ii15.
12. Lodge B, Wynn GJ, Das M, Cabrera S, Webber M, Morgan M, Gupta D, Todd DM.
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Dhiraj Gupta
Dec 2015
Patient reported outcomes (PROMS) in catheter ablation of atrial fibrillation. Europace
2014, 16:ii85.
13. Wynn GJ, Haq I, Hung J, Bonnett LJ, Lewis G, Kennedy T, Das M, Webber M, Modi SS,
Snowdon RL, Hall MCS, Waktare JEPW, Todd DM, Gupta D. Use of ultrasound to
reduce vascular complications associated with atrial fibrillation ablation: a prospective
study. Europace 2014, 16:ii85.
14. Wynn GJ, Das M, Bonnett LJ, Hall MCS, Snowdon RL, Waktare JEPW, Modi SS, Todd
DM, Gupta D. The Ablation Effectiveness Quotient: a novel marker to predict the
success of atrial fibrillation ablation. Heart 2014, 100:A6-7.
15. Wynn GJ, Haq I, Hung J, Bonnett LJ, Lewis G, Webber M, Das M, Kennedy T, Waktare
JEPW, Modi SS, Snowdon RL, Hall MCS, Todd DM, Gupta D. First, do no harm.
Improving safety in catheter ablation for atrial fibrillation: a prospective study of the use
of ultrasound to guide vascular access. Heart 2014, 100:A5-6.
Ongoing Research Projects
Pulmonary vein re-isolation as a routine Strategy: a Success Rate Evaluation
(PRESSURE): Chief Investigator
Randomised prospective trial evaluating the incidence and nature of Pulmonary Vein
reconnection at routine invasive study at 8 weeks, and the clinical impact of re-isolation of
these veins-Recruiting
The value of Ablation index to predict sites of acute Pulmonary Vein Reconnection
following ablation for Atrial Fibrillation: Principal Investigator
International Multicentric Study with centres from Bruges, Freiburg, Aarhus and Oklahoma
Catheter ablation vs Surgical Ablation for AF (CASA-AF): Principal Investigator
NIHR funded 3 centre trial with Royal Brompton and Harefield Hospitals
Pulmonary vein Reconnection following Ablation Index-guided ablation: a Success
Evaluation (PRAISE): Chief Investigator
International multi-centre trial with Centro Cardiologico Monzino, IRCCS, Milan, Italy and
Freeman Hospital, Newcastle
Teaching Experience
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I am a manuscript reviewer for the Journal of the American College of Cardiology: Arrhythmia and
Electrophysiology and the Journal for Atrial Fibrillation
I am regularly invited to give external lectures to learned societies such as British Heart Rhythm
Society and British Cardiac Society, and to the Swiss Heart Rhythm Society
Memberships of Learned Societies
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Royal College of Physicians (Fellow)
British Cardiac Society
British Heart Rhythm Society
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