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Acute versus chronic cardiac failure
Right ventricular failure/ left ventricular failure/ congestive cardiac failure
Systolic failure/diastolic failure
Compensated and decompensated cardiac failure
CLASS -21/1/16 , TOPIC -EARLY & LATE DISTAL TUBULE TIME—8-9AM
EARLY DISTAL TUBULE
SEGMENTS
TRANSPORTER
FUNCTION
Distal tubules
MACULA DENSA
senses the NaCl conc.
NaCl COTRANSPORTER
SODIUM UPTAKE
CHLORIDE UPTAKE
Ca +2 ATPase
Sodium calcium exchanger
Paratharmone
G PROTEIN
THIAZIDE DIURETICS
INHIBITING NaCl co transporter
S
LATE DISTAL TUBULE
SEGMENTS
Late distal tubule
SPECIAL FEATURE
Principal cell
Intercalated cell
Dr. Anshul Sharma
Date :-22.1.2016
FUNCTION
Principal cells reabsorb sodium
& water from the lumen secret
potassium ion into lumen.
Intercalated cells reabsorb
potassium ions and secret
hydrogen ions into tubular
lumen.
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