Download INTEGRAL UNIVERSITY Department of Chemistry Evaluation Scheme

INTEGRAL UNIVERSITY
Department of Chemistry
Evaluation Scheme
M.Sc. (INDUSTRIAL CHEMISTRY)
SEMESTER-II
S.
Course
N
code
.
1. IC-121
Subject
Periods
Theory
Chemical Process
Industry
L
03
T
01
P
00
Evaluation Scheme
Sessional
ESE
CT TA Total
15 10
25
75
Subject
Total
100
2.
IC-122
Physical Chemistry,
Industrial
Applications
03
01
00
15
10
25
75
100
3.
IC-123
Pharmaceutical
Chemistry
03
01
00
15
10
25
75
100
4.
IC-124
Modern Analytical
Techniques
03
01
00
15
10
25
75
100
00
00
06
15
10
25
75
100
Practical
5.
IC-12 P
Industrial Chemistry
Lab-II
Total
500
REVISED SYLLABUS 2013
M.Sc. (Industrial Chemistry)
Semester II
CHEMICAL PROCESS INDUSTRY
(IC-121)
LTP310
UNIT I
08 hours
Ceramics: Introduction, Classification , General Properties, Basic raw materials and
Manufacturing Process, Manufacturing of Earthenwares & Stonewares.
Refractories: Classification, General properties, Basic raw materials and Manufacturing
process. Manufacturing of Fire Clay Bricks & High Alumina refractories.
UNIT II
08 hours
Glass: Introduction, Physical & Chemical Properties, Raw Mateirals , Chemical Reactions and
Methods of Manufacturing.
Cement: Introduction, Composition , Types, Basic raw Materials, manufacturing by wet & Dry
process, Reaction in the Kiln, setting of cement.
UNIT III
08 hours
Sugar: Intruduction , Raw materials, Manufacture of sugar from Cane sugar, Cane sugar
refining, By-products from sugar industries and their uses.
Pulp & paper: Various types of Pulps, Manufacture of pulps, Papers, Polymer modified
papers, Board and structural materials.
UNIT IV
08 hours
Adhesives: Introduction, Process of bonding, Classification of adhesives, Preparation of
adhesives like Animal glue, Starch adhesives, Synthetic resin adhesives, Cellulose and
silicate adhesives, Applications of various adhesives.
UNIT V
08 hours
Leather: Introduction, Animal skins, Manufacture of leather, Byproducts, Chemicals used
in leather industries.
Fertilizers: Introduction, Classification, Manufacturing of: Urea, Ammonium nitrate, Normal
super phosphate & Triple super phosphate.
Books recommended:
.
Chemical process industries N.R Nerris shreve
Chemical process principales: part 1 & II – O.A / Hougen, K.M Watson RA Ragatz
(CBS)
Shrev’s Chemical process Industries: 5th edition – George T. Austin, Mc Graw Hill
Book Co.
Handbook of industrial chemistry: Volume I & II , KH Davis , FS Berner, CBS
Publication.
Plastic Additives Technology Hand Book: Himadri Panda, Engineers India Research
Institute.
 Industrial Chemistry B.K.Sharma, goel publishing house
REVISED SYLLABUS 2013
M.Sc. (Industrial Chemistry)
Semester- II
PHYSICAL CHEMISTRY, INDUSTRIAL APPLICATIONS
IC-(122)
LTP310
UNIT-I
08 hours
Thermodynamics: Combined form of the First and Second laws of Thermodynamics;
Concept of free energy, Free energy functions and their discussion; Thermodynamic
equilibrium and free energy functions; Free energy of the system and entropy of the
universe; Chemical Potential, Gibbs-Duhem equation; Chemical potential and
thermodynamic functions; Chemical potential of a pure substance; Chemical potential of
ideal gas mixture; Fugacity and its determination; Thermodynamic criteria for non-equilibrium
states, Entropy production and Entropy Flow.
UNIT-II
08 hours
Statistical Thermodynamics: Common terms; Thermodynamical probability; Probability
of entropy; The Boltzmann Distribution law; The partition function, Thermodynamic
properties in terms of partition function; Partition function of polyatomic molecules;
Translational, Rotational and Vibrational partition functions; Equilibrium constant and
partition function.
UNIT-III
08 hours
Chemical Kinetics: Theory of reaction rates; Collision theory of reaction rates; Steric factor and
activated complex theory; Arrhenius equation and activated complex theory; Dynamics of
unimolecular reaction (Lindemann-Hinshelwood and Rice-Ramsperger Kessel ); Marcus
theories of unimolecular reaction; Kinetics of enzyme reactions.
UNIT-IV
08 hours
Electrochemistry: Electrochemistry of solutions; Electro catalysis Bioelectrochemistry; NernstPlank Equation; Electrocardiography; Activity and activity coefficient; Debye-Huckel Theory
for activity Coefficient of electrolytic solution; Determination of activity coefficient; Ionic
strength.
UNIT-V
08 hours
Photochemistry: Laws of Photochemistry; Quantum Efficiency and its determination;
Photochemical relations and their kinetics (Hydrogen-Bromine and Hydrogen-Chlorine
reaction); Flame photometry; Quantitative Fluorescence analysis.
Books recommended:
Physical Chemistry, P.W. Atkins, ELBS
Quantum Chemistry, Ira N. Levine, Prentice Hall
Thermodynamics – J. Rajaram and J.C. Kuriacose – Educational Publishers.
Physical Chemistry of Surfaces – A.W. Adamson – John Wiley Sons.
Quantum Chemistry – Eyring, Walter, Kinball
Statistical Physics (Part I) (Course of Theoretical Physics Vol. 5) – L.D. London. &
E.M. Lefshitz Perganion Zpress, London.
Chemical Thermodynamics by R.P.Rastogi et al
Principles of Physical Chemistry by Puri, Sharma and Pathan
REVISED SYLLABUS 2013
M.Sc. (Industrial Chemistry)
Semester II
PHARMACEUTICAL CHEMISTRY
(IC-123)
LTP310
Unit-I
10 hours
Antibiotics and Sulpha Drugs:Introduction and classification of antibiotics; beta lactam
antibiotics: penicillins, its structure and mode of action, synthesis of Penicillin-v.
Cephalosporins: classification, structure and mode of action of first, second, third and fourth
generation cephalosporins. Aminoglycoside antibiotics: structure and mode of action of
Streptomycin, Neomycin and Kenamycin. Chloramphenicol: its structure, synthesis and mode of
action. Synthesis and uses of sulphathiazole, sulphaguanidine, sulphadiazine, sulphamethazine
and sulphaacetamide.
Unit-II
06 hours
Antipyretics analgesics: Introduction, classification, structure, synthesis and uses of analogues of
p-aminophenol: Paracetamol, Phenacetin and antifebrin; Salicylic acid analogues: Aspirin, Salol,
Salsalate and benorilate; Pyrazolones and Pyrazolodinones analogues: Antipyrine, Aminopyrin,
Dipyrone, Phenylbutazone, Oxyphenbutazone and Sulphinpyrazone
Unit-III
08hours
Anesthetic drugs: Introduction, Classification, Synthesis and mode of action of: Inhalation
anesthetics: Vinyl ether, Cyclopropane and Fluoroxene; Intravenous anesthetics: Thiopental
Sodium & Methohexital Sodium; Basal anesthetics: Procanine hydrochloride, Tetracaine
hydrochloride, Butacaine hydrochloride, Benzamine hydrochloride and Pyrocanine
hydrochloride.
Unit-IV
10hours
Cardiovascular drugs: Introduction, classification, structure and mode of action of cardiac
glycosides Digoxin, and Digitoxin; Anti-hypertensive and hypotensive drugs: structure, synthesis
and mode of action of Losartan, Clonidine, Hydralazine, Methyldopa and Diazoxide;
Antiarrhythmic agents: structure, synthesis and mode of action of Diisopyramide, Procainamide,
Propranolol, Beritylium Tosilate;Vasopressor drugs: structure, synthesis and mode of action of
Isoxsupurine, Prenyl amine.
Unit-V
06hours
Drug Design: Introduction; analogues and prodrugs; concept of lead; factors governing
drug design; rational approach to drug design; Drug design: the method of variation; Drug
design and development: preamble, revolutions in drug discovery, research and
development strategies.
Books recommended:
Burger’s Medicinal Chemistry: Mangrove E. Wolff, 4th Edition, John Wiley and Sons
Medicinal Chemistry by Asutosh Kar , New Age International publication
Principles of Medicinal Chemistry: W.O. Foye.
The Pharmacological Basis of Theraputics : L.S. Goodman and A. Gilman
Wilson’s Medicinal Chemistry
The Organic Chemistry of Drug Synthesis: D. Lednicer and L.A. Mitscher,
REVISED SYLLABUS 2013
M.Sc. (Industrial Chemistry)
Semester II
MODERN ANALYTICAL TECHNIQUES
(IC-124)
LTP310
Unit-I
08 hours
UV Spectroscopy
Wave-like propagation of light, absorption of electromagnetic radiation by organic molecules
allowed and forbidden transitions, instrumentation, effect of solvents on electronic transitions,
formation and designation of absorption bands, conjugated systems and transition energies,
unsaturated carbonyl compounds, dienes and conjugated polyenes, Woodward – Fieser rules.
Unit-II
08 hours
IR Spectroscopy
Introduction, absorption in the infrared region, theory of infrared spectroscopy, instrumentation,
molecular vibrations, calculation of vibrational frequencies, factors affecting vibrational
frequencies, characteristic absorptions in common classes of compounds, fingerprint region,
characteristic vibrational frequencies of alkanes, alkenes, alkynes, aromatic compounds,
alcohols, ether, phenols and amines. Detailed study of vibrational frequencies of carbonyl
compounds (ketones, aldehydes, esters, acids, anhydrides), applications of infrared spectroscopy.
Unit-III
08 hours
NMR Spectroscopy
Introduction, theory of NMR spectroscopy, instrumentation, chemical shift, equivalent and
nonequivalent protons, spin-spin splitting, vicinal coupling and stereostructure, proton exchange
reactions, nuclear overhauser effect (NOE), shift reagents, principle of C-13 NMR spectroscopy,
Relaxation and dynamic processes - Spin lattice relaxation (T1) and Spin - spin relaxation (T2)
measurements. Interpretation of NMR spectra of some representative compounds.
Unit-IV
08 hours
Mass Spectrometry
Introduction, basic theory, instrumentation, important useful terms in mass spectrometry,
various modes of ionization (EI, CI, FD and FAB) and their applications, fragmentation patterns
of various functional groups (alkanes, alkenes, alkynes, alcohols, ether, phenols and amines,
ketones, aldehydes, esters, acids, anhydrides), molecular ion peak, metastable peak,
Mclafferty rearrangements, Nitrogen rule.
Unit-V
08 hours
Atomic Absorption Spectrophotometry:
Introduction, Principle, Instrumentation, Interferences- Spectral, Ionization, Physical and
Refractory compound formation, Sample preparation, Internal standard and standard
addition calibration and applications of AAS.
Books recommended:




Introduction to spectroscopy: Pavia, Lampman & Kriz, 3rd Ed, Books/cole.
Spectroscopic methods in organic chemistry: H. Williams and Ian fleminig, V Edition
Tata Mc Grawhills
Organic spectroscopy: William Kemp, 3rd Edition, Palgrave publications.

Fundamentals of Analytical chemistry, Douglas A. Skoog, Donald M. West, F. James
Holler, 7th edition, Harcourt college publications.
Principles and practice of analytical chemistry, F. W. Fifield, D. Kealey, 5th edition,
Blackwell publication.
Analytical chemistry, Gary D. Christian, 6th edition, Wiley and sons publication.
Spectrometric identification of organic compounds, R. M. Silverstein, 6th edition, John
Wiley and sons.
Basic concepts of analytical chemistry, S. M. Kopper, New Age International Publishers.
Analytical chemistry, D. Kealey, P.J.Haines, Viva books Pvt. Ltd
Analytical Chemistry – Instrumental techniques Vol. I, Mahindu singh, Dominent
publication.





