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AUTOMATED SEGMENTATION OF TEETH FROM CBCT IMAGES Johannes Keustermans1, Wouter Mollemans1, Filip Schutyser1, Dirk Vandermeulen1 and Paul Suetens1 1 K.U.Leuven, Faculty of Engineering, ESAT/PSI, Medical Image Computing UZ Gasthuisberg, Herestraat 49 bus 7003, 3000 Leuven, Belgium ABSTRACT AIM The introduction of Cone-Beam Computed Tomography (CBCT) has instigated a breakthrough for the routine computer-aided planning of orthognatic surgery or orthodontic treatment, due to its low radiation dose, unique accessibility and low cost. These applications require the segmentation of certain anatomical structures of interest, like bone and soft tissue. The segmentation of teeth from the images is of particular interest for certain applications, e.g. virtual tooth extraction and orthodontic treatment planning and evaluation. Yet, the segmentation of teeth is hampered by mainly two factors. Firstly, the presence of metal streak artifacts caused by orthodontic braces or dental fillings, and secondly, since the teeth are anchored in the jaw bone there is only little contrast between the bone and the teeth, predominantly at the level of the apex. In this abstract, we present an automated method for the segmentation of teeth from CBCT images. MATERIALS AND METHODS The presented method incorporates prior information on the individual teeth, captured from a set of training data consisting of CBCT images with manually segmented teeth. This prior information is twofold. Firstly, the overall shape of each tooth is captured by a statistical model, describing the average shape and its possible variations. Secondly, the image information is captured by approximating the grey values present in the image surrounding each tooth by a constant grey value inside and a constant grey value outside of each tooth. Therefore the presented method consists of two phases. In the first phase, the statistical model describing the shape of each individual tooth is built, whereas in the second phase this model is used for the segmentation of the respective tooth. RESULTS To judge the potential of this method, an initial validation study is performed. Therefore, this method is applied to the segmentation of the upper left canine and the upper left first molar. A training data set of 22 CBCT images (0.4x0.4x0.4mm) is used in which the upper left canine and the upper left first molar are manually segmented. Based on a leave-one-out approach applied to the training data, preliminary results are obtained. This approach consists of removing a single training sample from the set of training data, building the statistical model describing the shape on the remaining training data, and applying the method to the removed training sample. Using this approach the potential and accuracy of the method is shown. SUMMARY In this abstract a statistical model-based method is presented for the automated segmentation of teeth from CBCT images. As an initial test this method is applied to the segmentation of the upper left canine and the upper left first molar. The results of this initial validation study show some promising results, indicating the potential of this method. In the future we would like to try to extend this method to the segmentation of other teeth, as well as performing a more extensive and quantitative validation study.