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Evaluating the integration of nutritional support into the surgical management of colorectal cancer patients Sorrel Burden, University of Manchester Email : [email protected] Summary The aim of this fellowship is to undertake exploratory work to investigate why 66% of patients with colorectal cancer lose weight prior to surgery and to test if a simple intervention can help with nutritional status. Background Previous research found that 66% of patients with colorectal cancer lose weight prior to surgery and 28% lose more than 10% of their body weight in the 6 months preceding surgery. Loss of more than 10% of body weight is an indicator of malnutrition. Research has also found that gastrointestinal surgical patients who are losing weight and malnourished suffer more post-operative complications and the length of time needed to recover is increased. The researcher is a dietitian, and work undertaken for her PhD demonstrated clinical benefits of supportive nutritional interventions. The national guidelines for Improving Outcomes in Colorectal Cancer do not mention nutrition. However, lack of research in this area is a factor in the omission of nutrition as a supportive intervention for colorectal cancer patients from pivotal reports and guidance that influence service provision. This research aims to explore the role of supportive preoperative nutritional management in the treatment of colorectal cancer patients. Findings The study concludes 30 September 2013. Why is this work important? Nutritional support during treatment for patients forms the mainstay of work for dietitians working on gastrointestinal wards. However, benefits of preoperative nutritional support are not formally recognised in national guidelines for the treatment of colorectal cancer. This form of support could be extremely valuable to patients. Information for this research will be gathered through interviews and focus groups with patients with colorectal cancer and a literature review. A controlled trial of a nutritional intervention in colorectal cancer patients will also be conducted as part of the study. Publications or other outputs related to this research Burden ST, Hill J, Molassiotis A, Todd C. Exploring the experience of colorectal cancer patients in relation to food and nutrition in survivorship. Submitted to Cancer Survivorship Journal Burden ST, Hill J, Molassiotis A, Todd C. Colorectal cancer patients’ experiences of food and nutrition issues: a qualitative evaluation. Submitted to Clinical Nutrition Burden S, Todd C, Hill J, Lal S. Preoperative Nutrition in Patients Undergoing Gastrointestinal Surgery. (Protocol). Cochrane Database of Systematic Reviews. 2010. Issue 12. Art.No: CD008879. DOI: 10.1002/14651858.CD008879. Burden ST, Hill J, Shaffer J, and Todd C. A randomized controlled trial of preoperative oral sip feeding in colorectal cancer patients. Journal of Human Nutrition and Dietetics. 2011. 24: 441-443