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Special Funding to Support SARS Research Proposals List of Supported Projects Proposal No. Proposal Title Principal Investigator CityU 1511/03E Development and Site Verification of a Dr Albert Ting Virus Cleaner (Intentionally Designed Pat So for SARS Triage Wards) Amount Duration Supported Supported ($) (months) 560,200 9 CUHK 4507/03M To Develop a Clinical Prognostic Prof Nelson Profile for Severe Disease Course in Leung Sang SARS with Serum Cytokines Tang Measurements and Genomic Markers A Retrospective Case Control Study 362,000 12 CUHK 4508/03M Quantitative Analysis of Plasma Viral and Host RNA in Severe Acute Respiratory Syndrome Prof Dennis Yuk Ming Lo 415,800 12 CUHK 4527/03M Development of Specific Immunotherapeutics and rapid immunodiagnostics for severe acute respiratory syndrome Prof Pak Leong Lim 400,000 12 CUHK 4532/03M A Population-based Study on the Prevalence of SARS-associated Coronavirus Infection in Hong Kong Prof Francis Ka Leung Chan 1,330,000 12 CUHK 4536/03M Establishment of a SARS Coronavirus Prof Mary Miu Protein/Peptide Library and an Yee Waye Antibody Library as Common Platforms for Biological and Medical Applications 800,000 12 PolyU 5520/03M Development of Sensitive Diagnostic Assays for Human Coronavirus Causing SARS Dr Shea Ping Yip 552,000 12 HKUST 6505/03M Identify viral epitopes for Prof Zhihong immunoglobulins from SARS patients Guo 652,000 12 HKUST 6510/03M Development of anti-SARS therapeutics using multiple molecular strategies 552,000 12 Prof Chun Liang Proposal No. Proposal Title Principal Investigator HKU 7529/03M Development of monoclonal antibodies Prof Kar Neng against SARS-associated coronavirus: Lai specific targeting for early diagnosis and future treatment Amount Duration Supported Supported ($) (months) 750,000 12 HKU 7531/03M Mechanism of SARS-coronavirus pathogenesis - identification of viral genes implicated in immune dysregulation Dr Allan Sik Yin Lau 512,000 12 HKU 7532/03M Enzyme-linked immunosorbant assay (ELISA) – based antigen test for rapid diagnosis of severe acute respiratory syndrome (SARS) Dr Susanna Kar Pui Lau 500,000 12 HKU 7542/03M Genetic variation of the SARS coronavirus: molecular epidemiology and antigenic variation Prof Joseph Sriyal Malik Peiris 1,012,000 12 HKU 7543/03M Rapid molecular diagnosis of SARS coronavirus Dr Leo Lit Man Poon 450,000 12 HKU 7551/03M A study of antiviral peptides targeting spike and matrix proteins of SARS coronavirus Dr Bojian Zheng 652,000 12 500,000 12 HKU 7553/03M Rapid accurate diagnostic assay for the Dr Frederick SARS coronavirus Chi Ching Leung Total: 10,000,000