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UIC
Illinois Eye and Ear Infirmary
Department of Ophthalmology & Visual Sciences
University of Illinois College of Medicine
O n e
VISION
UPDATE 2011
In this issue
New Faculty
2
Faculty4
Publications6
Dr. Alexander Retirement
11
NEI K12 Grant
12
Residents and Fellows
14
Sponsored Research
16
18
Tissue Donor Feature
Clinical Investigations/Trials
20
Giving22
Renovations & Innovations
26
International Doctors
28
I
t is my pleasure to update you on the developments in the Department of Ophthalmology and
Visual Sciences in 2011, which continues to grow and succeed in every area of our mission.
Five years ago I established a clinician-scientist readiness program in the Department. This
program provided protected research time and research support to faculty desiring a clinicianscientist career. The program was instrumental for three of our faculty in obtaining clinicianscientist awards from the National Institutes of Health (individual K awards). I am extremely
pleased to announce that the Department received a five-year K12 award from the National Eye Institute last
September to support the “UIC K12 Independent Clinical Scientist Development Program” and that three
MD, PhD clinician scientists have joined this program! We are one of six Ophthalmology Departments in the
nation to be actively supported by the K12 award. As a result of these efforts, the number of NIH-funded
clinician-scientists in the Department has now grown from two to a total of nine over the past five years.
These clinician-scientists are part of a group of 18 highly talented young faculty recruited during the past 5
years primarily at the assistant professor level. This group represents the future leadership of the Department,
contributing to its continued growth into a world class ophthalmological institute.
Over the past five years, the clinical facilities have seen continual growth and renovations. We have expanded
and renovated the Retina, Cornea, Contact Lens, Glaucoma, General Eye, Oculoplastic Surgery, and NeuroOphthalmology Services. This year, the Pediatric Ophthalmology and Adult Strabismus Service is being
renovated. We have also established a Low Vision Service and a Comprehensive Ophthalmology Faculty
Practice. The Millennium Park Eye Center, established in 2007, now provides clinical care in all ophthalmic
specialties.
The educational mission of the department remains very strong. We established the Illinois Eye Review program
in 2008 to coincide with the 150 th celebrations of the Illinois Eye and Ear Infirmary. This week-long review
program is now in its fifth year and draws approximately 300 national and international participants every year.
Additionally, the department has established a new exchange program with Brazil, which is modeled on our
highly successful resident exchange program with Keio University in Japan.
Despite the challenges of limits on federal funding to the National Institutes of Health, our basic science
research program remains very strong especially with the recruitment of Drs. Dingcai Cao and Jason McAnany,
both Principal Investigators for National Eye Institute grants. The departmental core grant, of which I serve as
the PI, was renewed through 2014. The Department also received a grant this year to provide a state-of-the
art animal facility dedicated to ophthalmology. Research to Prevent Blindness led the way in supporting our
corneal, glaucoma and retinal research efforts. These grants, as well as other philanthropic support, have been
critical in equipping the core research facilities with advanced cell and molecular biology technology, such as
live-cell confocal microscopes.
In closing, I have tremendously enjoyed my tenure as Department Head and I am privileged to have contributed
to the successes that the Department has achieved in recent years. Thanks to the generous support of our
alumni and donors and the tireless effort of our faculty, residents, fellows and staff, the Department has
strengthened its position as a leading ophthalmological institution. As I transition to the Dean’s office, we will
continue to be guided by our institutional mission of academic excellence in education, translational research,
serving the underserved and treating the most complex medical conditions.
Dimitri T. Azar, MD, MBA
Interim Dean, College of Medicine
B.A. Field Endowed Chair of Ophthalmologic Research
Professor and Department Head, Ophthalmology and Visual Sciences
Department of Ophthalmology & Visual Sciences | Treating the most serious and complicated ophthalmology cases for over 150 years
ophthalmology
Attracts New Talent
2
Ahmad Aref, MD
Dingcai Cao, PhD
Assistant Professor of Ophthalmology
Glaucoma Service
Associate Professor of Ophthalmology
Director, Visual Perception Laboratory
Dr. Aref is an Assistant Professor of Ophthalmology and an attending
physician in the Glaucoma Service. His practice concentrates
on minimally invasive glaucoma surgery for patients with mild
to moderate glaucomatous disease, particularly those who are
experiencing difficulties associated with a medical regimen and the
management of glaucomas related to prior vitreoretinal surgical
interventions. Dr. Aref joined the faculty in August 2011. Dr. Cao joined the Ophthalmology faculty in September 2011 as
a member of the research faculty. He is the principal investigator
of a National Eye Institute research grant, Rod-cone Interactions
in Mesopic Vision (R01EY1019651). Dr. Cao joins UIC from the
University of Chicago, where he earned a PhD in Biopsychology
and served on U of C’s ophthalmology faculty. Dr. Cao’s research
focuses on finding what the neural mechanisms are that mediate
visual processing, and how retinal diseases affect visual functions.
Undergraduate
BS, University of Michigan
Medical School
MD, Northwestern University Feinberg
School of Medicine
Residency
Penn State Hershey Eye Center
Fellowship
Glaucoma, Bascom Palmer Eye Institute of
the University of Miami School of Medicine
Undergraduate
BS, Psychology, Beijing University
Graduate School
MS, Biopsychology, Beijing University
MS, Statistics, University of Chicago
Doctorate
PhD, Biopsychology, University of Chicago
Fellowship
Postdoctoral Fellow,
Department of Ophthalmology and
Visual Sciences, University of Chicago,
Laboratory of Dr. Joel Pokorny
Iris Kassem, MD, PhD
Jason McAnany, PhD
Assistant Professor of Ophthalmology
Pediatric Ophthalmology and
Adult Strabismus Service
Assistant Professor of Ophthalmology
Director, Clinical Psychophysics and
Electrophysiology Laboratory
Dr. Kassem is an Assistant Professor of Ophthalmology and an
attending physician in the Pediatric Ophthalmology and Adult
Strabismus Service. She specializes in amblyopia, pediatric cataracts
and pediatric ocular trauma. Dr. Kassem completed her year-long
Pediatric Ophthalmology and Adult Strabismus fellowship at UIC in
July, before joining the faculty in September 2011.
Dr. McAnany joined the Department of Ophthalmology in
September 2011 as a member of the research faculty. He is the
principal investigator of a National Eye Institute research grant,
Mechanisms Limiting Visual Performance in Retinal Degenerations
(R00EY019510). His research is focused on defining the relationship
between visual dysfunction and the underlying disease processes
using psychophysical, electrophysiological, and other noninvasive
test procedures, with the goal of developing novel methods for
diagnosing and monitoring the progression of visual dysfunction.
Undergraduate
BS, Cornell University
Medical School
MD, SUNY Health Science Center at Stony
Brook
Residency
North Shore-Long Island Jewish Health
System
Fellowship
Pediatric Ophthalmology and Adult
Strabismus, UIC
Undergraduate
BA, Psychology/Biology, Eastern Michigan
University
Graduate School
MA, Psychology/Behavioral Neuroscience,
UIC
Doctorate
PhD, Psychology/Behavioral Neuroscience,
UIC
Fellowship
Department of Ophthalmology
and Visual Sciences, UIC
Laboratory of Dr. Kenneth Alexander
3
Department of Ophthalmology & Visual Sciences | Treating the most serious and complicated ophthalmology cases for over 150 years
faculty
Chairs and Vice Chairs
Allen Putterman, MD15
Professor of Ophthalmology
Co-Director, Oculoplastic Surgery Service
Dimitri Azar, MD, MBA
1
Interim Dean, College of Medicine
BA Field Endowed Chair of Ophthalmologic Research
Professor and Department Head of Ophthalmology
and Visual Sciences
Harris Ripps, PhD, DSc16
Alexander Khammar, MD50
Clinical Assistant Professor of Ophthalmology
Clinical Assistant Professor of Ophthalmology
Ahmad Aref, MD33
Charles Kinnaird, OD51
Assistant Professor of Ophthalmology
Clinical Assistant Professor of Ophthalmology
Victoria Butcko, OD34
Yannek Leiderman, MD, PhD52
William Mieler, MD3
Jacob Wilensky, MD18
Morton F. Goldberg MD Professor of Ophthalmology
Vice Chair for Research
Director, Applied Physics Laboratory
Professors
Kenneth Alexander, PhD5
Professor Emeritus
Professor of Ophthalmology
Professor of Ophthalmology
Director, Retinal Circulation and Metabolism Laboratory
Debra Goldstein, MD7
Professor of Ophthalmology
Director, Uveitis Service
Beatrice Yue, PhD19
Thanis A. Field Professor of Ophthalmology
Director, Ocular Cell Biology Laboratory
Adjunct Professor
Nathalie Azar, MD20
Felix Chau, MD37
Dingcai Cao, PhD21
Soledad Cortina, MD38
Associate Professor of Clinical Ophthalmology
Director, Pediatric Ophthalmology and Adult Strabismus
Ali Djalilian, MD22
Kimberlee Curnyn, MD
James Goodwin, MD23
Jose de la Cruz, MD40
Professor Emeritus
Nalin Kumar, DPhil9
Paul Knepper, MD, PhD
Jennifer Lim, MD
Research Scientist
Marion Schenk Esq., Chair of Ophthalmology
Director, Retina Service
Michael Shapiro, MD26
Clinical Associate Professor
Deepak Shukla, PhD27
Irene Maumenee, MD11
Clinical Assistant Professor
Anthony Finder, MD
41
Clinical Assistant Professor of Ophthalmology
Robert Fitzgerald, MD42
Clinical Assistant Professor of Ophthalmology
Molly Gilbert, MD43
Clinical Assistant Professor of Ophthalmology
Director, Resident Education,
James A. Lovell Federal Health Care Center
Research Professor of Ophthalmology
Director, Ocular Genetics Laboratory
Michael Grassi, MD44
Timothy McMahon, OD
Joan Stelmack, OD28
Anil Gulati, MD45
Professor of Ophthalmology
Marilyn Miller, MD13
Professor of Ophthalmology
Clinical Associate Professor of Ophthalmology
Director, Low Vision Service
Benjamin Ticho, MD29
Clinical Associate Professor
David Pepperberg, PhD14
Searls-Schenk Professor of Ophthalmology
Director, Photoreceptor Research Laboratory
Elmer Tu, MD30
Associate Professor of Clinical Ophthalmology
Director, Cornea Service
Amy Lin, MD53
Assistant Professor of Pathology
Assistant Professor of Ophthalmology
Director, Ophthalmic Pathology Laboratory
Mark Lunde, MD54
Clinical Assistant Professor of Ophthalmology
Director of Resident Education, Jesse Brown Veterans
Administration
Assistant Professor of Ophthalmology
Heather Moss, MD, PhD56
Assistant Professor of Ophthalmology
Director, Neuro-Ophthalmology Research Program
Nasser Qtaishat, PhD57
Marion Schenk Esq., Professor of Ophthalmology
Associate Professor of Microbiology and Immunology
Director, Ocular Virology Laboratory
12
4
39
Assistant Professor of Ophthalmology
Director, Millennium Park Eye Center
25
Assistant Professor of Ophthalmology
Director, Retinal Bank Laboratory
Jason McAnany, PhD55
Associate Professor of Ophthalmology
Director, Stem Cell Research Laboratory
Director of Medical Student Education in Ophthalmology
Associate Professor of Ophthalmology
Director, Contact Lens Service
10
Assistant Professor of Ophthalmology
Director, Retinal Bioengineering Laboratory
Assistant Professor of Ophthalmology
Director, Comprehensive Eye Service
and General Eye Service
Charlotte Joslin, OD, PhD
Professor of Ophthalmology
Research Assistant Professor of Ophthalmology
Director, Angiogenesis Research Laboratory
Research Assistant Professor of Ophthalmology
24
Gerald Fishman, MD8
Jin-Hong Chang, PhD35
Qing Chang, MD, PhD36
Associate Professors
Associate Professor of Ophthalmology
Director, Neuro-Ophthalmology Service
Anthony Adamis, MD
Assistant Professor of Ophthalmology
Clinical Assistant Professor of Ophthalmology
Associate Professor of Ophthalmology
Norman Blair, MD6
Iris Kassem, MD, PhD49
Amjad Ahmad, MD32
Professor Emeritus
Mahnaz Shahidi, PhD
Assistant Professor of Ophthalmology
Director, Corneal Neurobiology Laboratory
Janet Szlyk, PhD
Howard Tessler, MD17
4
Sandeep Jain, MD48
Assistant Professors
Professor of Ophthalmology
Vice Chair for Clinical Operations
Cornea Service
Professor of Ophthalmology
Vice Chair for Education
Director, Ocular Oncology Clinic, Retina Service
Associate Professor of Biostatistics in Ophthalmology
Associate Professor, College of Pharmacy
Professor Emeritus
Adjunct Professor
Joel Sugar, MD2
Marlos Viana, PhD31
Research Assistant Professor of Ophthalmology
Director, Retinal Chemical Genomics Laboratory
Clinical Assistant Professor
Kyuyeon Han, PhD46
Research Assistant Professor of Ophthalmology
David Hillman, MD47
Clinical Assistant Professor of Ophthalmology
Research Assistant Professor
Pete Setabutr, MD58
Assistant Professor of Ophthalmology
Director, Oculoplastic Surgery Service
Ellen Shorter, OD59
Assistant Professor of Ophthalmology
Director, PROSE Clinic
Aisha Traish, MD60
Assistant Professor of Ophthalmology
Associate Director, Residency Program
Director, Pediatric Cornea Clinic
Larry Ulanski, MD61
Clinical Assistant Professor of Ophthalmology
Thasarat Vajaranant, MD62
Assistant Professor of Ophthalmology
Director, Glaucoma Service
Minhua Wang, MD, PhD63
Research Assistant Professor of Ophthalmology
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Department of Ophthalmology & Visual Sciences | Treating the most serious and complicated ophthalmology cases for over 150 years
UIC Ophthalmology and Visual Sciences
faculty publications 2010-11
Journal Articles 07/01/10 – 06/30/11
virus type-1 infection. J Gen Virol. 2011 Apr;92(Pt 4):733-43.
Epub 2010 Dec 9. PubMed PMID: 21148276; PubMed Central PMCID: PMC3133699.
Aakalu VK, Putterman AM. Fat Repositioning in Lower Lid
Blepharoplasty: The Role of Titrated Excision. Ophthal Plast
Reconstr Surg. 2011 Mar 16. [Epub ahead of print] PubMed
PMID: 21415802.
Baker S, Booth C, Fillman C, Shapiro M, Blair MP, Hyland
JC, Ala-Kokko L. A loss of function mutation in the COL9A2
gene causes autosomal recessive Stickler syndrome. Am
J Med Genet A. 2011 Jul;155A(7):1668-72. doi: 10.1002/
ajmg.a.34071. Epub 2011 Jun 10. PubMed PMID: 21671392.
Aakalu VK, Sajja K, Cook JL, Ahmad AZ. Reply re: “Hyperbaric Oxygen Therapy as Further Adjunctive Therapy in
Group A Streptococcus Periorbital Necrotizing Fasciitis”.
Ophthal Plast Reconstr Surg. 2010 Aug 30. [Epub ahead of
print] PubMed PMID: 20811302.
Afshar AR, Oh FS, Birnbaum AD, Namavari A, Riddle JM,
Djalilian AR. Assessing ophthalmoscopy skills. Ophthalmology. 2010 Sep;117(9):1863,1863.e1-2. PubMed PMID:
20816257.
Amirjamshidi H, Milani BY, Sagha HM, Movahedan A, Shafiq
MA, Lavker RM, Yue BY, Djalilian AR. Limbal fibroblast
conditioned media: a non-invasive treatment for limbal stem
cell deficiency. Mol Vis. 2011 Mar 8;17:658-66. PubMed PMID:
21403854; PubMed Central PMCID: PMC3056128.
Anastasakis A, McAnany JJ, Fishman GA, Seiple WH.
Clinical value, normative retinal sensitivity values, and intrasession repeatability using a combined spectral domain optical coherence tomography/scanning laser ophthalmoscope
microperimeter. Eye (Lond). 2011 Feb;25(2):245-51. Epub
2010 Oct 29. PubMed PMID: 21178993; PubMed Central
PMCID: PMC3052979.
Anastasakis A, Fishman GA, Lindeman M, Genead MA,
Zhou W. Infrared scanning laser ophthalmoscope imaging
of the macula and its correlation with functional loss and
structural changes in patients with stargardt disease. Retina.
2011 May;31(5):949-58. PubMed PMID: 21293320; PubMed
Central PMCID: PMC3116073.
Anastasakis A, Thobani A, Fishman GA, McAnany JJ.
Educational levels in patients with stargardt disease. Am J
Ophthalmol. 2010 Nov;150(5):737-740.e2. Epub 2010 Aug 5.
PubMed PMID: 20688312.
Aref AA, Bennett T, Strong J, Kunselman AR, Scott IU. Effect of ophthalmic examination procedures on the quality
of spectral domain OCT images. Ophthalmic Surg Lasers
Imaging. 2011 Feb 1;42 Online:e1-3. doi: 10.3928/1542887720110125-06. PubMed PMID: 21323259.
Aref AA, Budenz DL. Spectral domain optical coherence
tomography in the diagnosis and management of glaucoma. Ophthalmic Surg Lasers Imaging. 2010 Nov-Dec;41
Suppl:S15-27. doi: 10.3928/15428877-20101031-01. Review.
PubMed PMID: 21117597.
Aref AA, Scott IU. Management of macular edema secondary to central retinal vein occlusion: an evidence-based.
Adv Ther. 2011 Jan;28(1):40-50. Epub 2010 Dec 9. Review.
PubMed PMID: 21153510.
Aref AA, Scott IU. Management of macular edema secondary to branch retinal vein occlusion: an evidence-based
update. Adv Ther. 2011 Jan;28(1):28-39. Epub 2010 Dec 9.
Review. PubMed PMID: 21153509.
Bacsa S, Karasneh G, Dosa S, Liu J,Valyi-Nagy T, Shukla D.
Syndecan-1 and syndecan-2 play key roles in herpes simplex
6
Belforte N, Sande P, de Zavalía N, Knepper PA, Rosenstein
RE. Effect of chondroitin sulfate on intraocular pressure in
rats. Invest Ophthalmol Vis Sci. 2010 Nov;51(11):5768-75.
Epub 2010 Jun 23. PubMed PMID: 20574017.
Beyer J, Zhao XC,Yee R, Khaliq S, McMahon TT,Ying
H, Yue BY, Malicki JJ. The role of crumbs genes in the
vertebrate cornea. Invest Ophthalmol Vis Sci. 2010
Sep;51(9):4549-56. PubMed PMID: 20805571; PubMed Central PMCID: PMC2941173.
Birnbaum AD, Jiang Y, Tessler HH, Goldstein DA. Elevation of intraocular pressure in patients with uveitis
treated with topical difluprednate. Arch Ophthalmol. 2011
May;129(5):667-8. Erratum in: Arch Ophthalmol. 2011
Jul;129(7):935. PubMed PMID: 21555625.
Birnbaum AD, Little DM, Tessler HH, Goldstein DA. Etiologies of chronic anterior uveitis at a tertiary referral center
over 35 years. Ocul Immunol Inflamm. 2011 Feb;19(1):19-25.
Epub 2010 Nov 6. PubMed PMID: 21054197.
Birnbaum AD, Oh FS, Chakrabarti A, Tessler HH, Goldstein DA. Clinical features and diagnostic evaluation of
biopsy-proven ocular sarcoidosis. Arch Ophthalmol. 2011
Apr;129(4):409-13. PubMed PMID: 21482866.
Birnbaum AD, Oh F, Sahin O, Little DM, Tessler HH, Goldstein DA. Chlorambucil and malignancy. Ophthalmology.
2010 Jul;117(7):1466-1466.e1. PubMed PMID: 20610006.
Birnbaum AD, Tessler HH, Goldstein DA. Sympathetic
ophthalmia in Operation Iraqi Freedom. Am J Ophthalmol.
2010 Nov;150(5):758-9. PubMed PMID: 21036221.
Cao D, Pokorny J, Grassi MA. Isolated mesopic rod and
cone electroretinograms realized with a four-primary method. Doc Ophthalmol. 2011 Aug;123(1):29-41. doi: 10.1007/
s10633-011-9279-9. Epub 2011 Jun 24. PubMed PMID:
21701875; PubMed Central PMCID: PMC3150787.
Chang JR, Koo E, Agrón E, Hallak J, Clemons T, Azar D,
Sperduto RD, Ferris FL 3rd, Chew EY; Age-Related Eye
Disease Study Group. Risk Factors Associated with Incident
Cataracts and Cataract Surgery in the Age-Related Eye Disease Study (AREDS) AREDS Report Number 32. Ophthalmology. 2011 Jun 17. [Epub ahead of print] PubMed PMID:
21684602; PubMed Central PMCID: PMC3178670.
Choi DE, Birnbaum AD, Oh F, Tessler HH, Goldstein
DA. Pediatric uveitis secondary to probable, presumed, and
biopsy-proven sarcoidosis. J Pediatr Ophthalmol Strabismus.
2011 May 1;48(3):157-62. doi: 10.3928/01913913-2010051801. Epub 2010 May 21. PubMed PMID: 20506967.
Chow CC, Kiernan DF, Chau FY, Blair MP,Ticho BH,
Galasso JM, Shapiro MJ. Laser photocoagulation at birth
prevents blindness in Norrie’s disease diagnosed using
amniocentesis. Ophthalmology. 2010 Dec;117(12):2402-6.
PubMed PMID: 20619898.
Cole EA, Winn BJ, Putterman AM. Measurement of
eyebrow position from inferior corneal limbus to brow: a
new technique. Ophthal Plast Reconstr Surg. 2010 NovDec;26(6):443-7. PubMed PMID: 20724865.
Cortina MS, Bazan HE. Docosahexaenoic acid, protectins and dry eye. Curr Opin Clin Nutr Metab Care. 2011
Mar;14(2):132-7. Review. PubMed PMID: 21157308.
Davis LT, Kumar N, Nijm LM, Ulanski LJ 2nd,Tu EY, Fiscella RG, Peterson RJ, Glickman RD. An adaptable HPLC
method for the analysis of frequently used antibiotics in
ocular samples. J Chromatogr B Analyt Technol Biomed Life
Sci. 2010 Sep 15;878(26):2421-6. Epub 2010 Aug 8. PubMed
PMID: 20739230.
Dhingra A, Fina ME, Neinstein A, Ramsey DJ, Xu Y, Fishman GA, Alexander KR, Qian H, Peachey NS, Gregg RG,
Vardi N. Autoantibodies in melanoma-associated retinopathy
target TRPM1 cation channels of retinal ON bipolar cells.
J Neurosci. 2011 Mar 16;31(11):3962-7. PubMed PMID:
21411639; PubMed Central PMCID: PMC3073846.
Dosa S, Castellanos K, Bacsa S, Gagyi E, Kovacs SK,ValyiNagy K, Shukla D, Dermody TS,Valyi-Nagy T. Chronic
progressive deficits in neuron size, density and number
in the trigeminal ganglia of mice latently infected with
herpes simplex virus. Brain Pathol. 2011 Sep;21(5):583-93.
doi: 10.1111/j.1750-3639.2011.00485.x. Epub 2011 Apr
3. PubMed PMID: 21371157; PubMed Central PMCID:
PMC3125479.
Drapala PW, Brey EM, Mieler WF,Venerus DC, Kang Derwent JJ, Perez-Luna VH., Role of thermo-responsiveness and
poly(ethylene glycol) diacrylate cross-link density on protein
release from poly (N-isopropylacrylamide) hydrogels. J Biomater Sci Polym Ed, 22 (2011), pp. 59–75.
Edward DP, Patil AJ, Sugar J, Parikh M. Copper deposition
in a variant of multiple myeloma: pathologic changes in the
cornea and the lens capsule. Cornea. 2011 Mar;30(3):360-3.
PubMed PMID: 21045663.
Elderkin S, Tu E, Sugar J, Reddy S, Kadakia A, Ramaswamy
R, Djalilian A. Outcome of descemet stripping automated
endothelial keratoplasty in patients with an anterior chamber intraocular lens. Cornea. 2010 Nov;29(11):1273-7.
PubMed PMID: 20697283.
Emerson MV, Saffra N, Louis LS, Lin AY, Folberg R,
Abramson DH. Anterior Segment Retinoblastoma Detectable on Magnetic Resonance Imaging. Retinal Cases and Brief
Reports, Summer 2010,4(3):243-245.
Emoto H, Emoto Y, Lim, JI, Sadun AA, Sebag J. Regression of
Choroidal Neovascularization After Vitrectomy for Postinjection Endophthalmitis. Retinal Cases and Brief Reports, Fall
2010,4(4):312-316.
Estrada-Cuzcano A, Koenekoop RK, Coppieters F, Kohl
S, Lopez I, Collin RW, De Baere EB, Roeleveld D, Marek J,
Bernd A, Rohrschneider K, van den Born LI, Meire F, Maumenee IH, Jacobson SG, Hoyng CB, Zrenner E, Cremers
FP, den Hollander AI. IQCB1 mutations in patients with leber
congenital amaurosis. Invest Ophthalmol Vis Sci. 2011 Feb
11;52(2):834-9. Print 2011 Feb. PubMed PMID: 20881296.
Farooq AV, Shukla D. Corneal latency and transmission
of herpes simplex virus-1. Future Virol. 2011 Jan;6(1):101108. PubMed PMID: 21436960; PubMed Central PMCID:
PMC3061464.
Fishman GA. Historical evolution in the understanding
of Stargardt macular dystrophy. Ophthalmic Genet. 2010
Dec;31(4):183-9. Epub 2010 Sep 1. PubMed PMID: 20809774.
Friberg TR, Tolentino M; LEVEL Study Group (Mieler EF),
Weber P, Patel S, Campbell S, Goldbaum M. Pegaptanib
sodium as maintenance therapy in neovascular age-related
macular degeneration: the LEVEL study. Br J Ophthalmol.
2010 Dec;94(12):1611-7. Epub 2010 May 14. PubMed PMID:
20472746; PubMed Central PMCID: PMC2991041.
Garcia JP Jr, Ritterband DC, Buxton DF, de la Cruz J. Evaluation of the stability of Boston type I keratoprosthesis-donor cornea interface using anterior segment optical coherence tomography. Cornea. 2010 Sep;29(9):1031-5. PubMed
PMID: 20517152.
Gatinel D, Malet J, Hoang-Xuan T, Azar DT. Corneal
elevation topography: best fit sphere, elevation distance,
asphericity, toricity, and clinical implications. Cornea. 2011
May;30(5):508-15. PubMed PMID: 21107250.
Genead MA, Fishman GA. Cystic macular oedema on
spectral-domain optical coherence tomography in choroideremia patients without cystic changes on fundus
examination. Eye (Lond). 2011 Jan;25(1):84-90. Epub 2010
Oct 22. PubMed PMID: 20966974; PubMed Central PMCID:
PMC3020991.
Genead MA, Fishman GA, Anastasakis A, Lindeman M.
Macular vitelliform lesion in desferrioxamine-related retinopathy. Doc Ophthalmol. 2010 Oct;121(2):161-6. Epub
2010 Jun 9. PubMed PMID: 20532952.
Genead MA, Fishman GA, Anastasakis A. Spectral-domain
OCT peripapillary retinal nerve fibre layer thickness
measurements in patients with Stargardt disease. Br J Ophthalmol. 2011 May;95(5):689-93. Epub 2010 Oct 8. PubMed
PMID: 20935302.
Genead MA, Fishman GA, Lindeman M. Structural and
functional characteristics in carriers of X-linked retinitis
pigmentosa with a tapetal-like reflex. Retina. 2010 NovDec;30(10):1726-33. PubMed PMID: 20829740; PubMed
Central PMCID: PMC2978770.
Genead MA, Fishman GA, McAnany JJ. Efficacy of topical dorzolamide for treatment of cystic macular lesions in a
patient with enhanced S-cone syndrome. Doc Ophthalmol.
2010 Dec;121(3):231-40. Epub 2010 Sep 15. PubMed PMID:
20842519.
Genead MA, McAnany JJ, Fishman GA. Retinal nerve fiber thickness measurements in choroideremia patients with
spectral-domain optical coherence tomography. Ophthalmic
Genet. 2011 Jun;32(2):101-6. Epub 2011 Jan 26. PubMed
PMID: 21268676.
Grassi MA, Tikhomirov A, Ramalingam S, Below JE, Cox NJ,
Nicolae DL. Genome-wide meta-analysis for severe diabetic
retinopathy. Hum Mol Genet. 2011 Jun 15;20(12):2472-81.
Epub 2011 Mar 26. PubMed PMID: 21441570; PubMed Central PMCID: PMC3098732.
Gupta S, Aakalu VK, Ahmad AZ. Late-onset orbital hematoma secondary to alloplastic orbital implant mimicking
transient ischemic attacks. Ophthal Plast Reconstr Surg.
2011 Jan-Feb;27(1):e18-20. PubMed PMID: 20700069.
Gupta S, Aakalu VK, Sajja K, Rosso RO, Ahmad AZ. Periorbital physical urticaria in an anophthalmic patient with
dermatographism. Ophthal Plast Reconstr Surg. 2011 JanFeb;27(1):e20-1. PubMed PMID: 21217333.
Gupta S, Blair MP, Lin AY, David O, Tessler HH, Goldstein DA. Cutaneous Melanoma Metastatic To the Vitreous
Cavity. Retinal Cases and Brief Reports, Retinal Cases and
Brief Reports, Summer 2011,5(3):197-200.
Gussin HA, Khasawneh FT, Xie A, Feng F, Memic A, Qian H,
Le Breton GC, Pepperberg DR. Subunit-specific polyclonal
antibody targeting human ρ1 GABA(C) receptor. Exp Eye
Res. 2011 Jul;93(1):59-64. Epub 2011 Apr 23. PubMed PMID:
21536029; PubMed Central PMCID: PMC3138833.
Gussin HA, Tomlinson ID, Muni NJ, Little DM, Qian H,
Rosenthal SJ, Pepperberg DR. GABAC receptor binding of
quantum-dot conjugates of variable ligand valency. Bioconjug
Chem. 2010 Aug 18;21(8):1455-64. PubMed PMID: 20715850;
PubMed Central PMCID: PMC2929923.
Henry JJ, Tsonis PA. Molecular and cellular aspects of
amphibian lens regeneration. Prog Retin Eye Res. 2010
Nov;29(6):543-55. Epub 2010 Jul 16. PubMed PMID:
20638484.
Hoang QV, Chau FY, Blair MP. Shapiro MJ. Optical Coherence Tomography of Nasal Sliding of the Retina and Temporal Arcades in Retinopathy of Prematurity. Retinal Cases
and Brief Reports. Spring 2011,5(2):165-166.
Hoang QV, Chau FY, Shahidi M, Lim JI. Central macular
splaying and outer retinal thinning in asymptomatic sickle
cell patients by spectral-domain optical coherence tomography. Am J Ophthalmol. 2011 Jun;151(6):990-994.e1. Epub
2011 Mar 31. PubMed PMID: 21457923.
Hoang QV, Blair MP, Rahmani B, Galasso JM, Shapiro MJ.
Multiple retinal holes and peripheral nonperfusion in muscleeye-brain disease. Arch Ophthalmol. 2011 Mar;129(3):373-5.
PubMed PMID: 21403000.
Hoang QV, Chau FY, Shahidi M, Miller MT, Blair MP.
Macular thinning associated with unilateral optic nerve
hypoplasia. Ophthalmic Surg Lasers Imaging. 2011 Feb 1;42
Online:e6-9. doi: 10.3928/15428877-20110125-08. PubMed
PMID: 21323261.
Hoang QV, Kiernan DF, Chau FY, Shapiro MJ, Blair MP.
Fluorescein angiography of recurrent retinopathy of prematurity after initial intravitreous bevacizumab treatment.
Arch Ophthalmol. 2010 Aug;128(8):1080-1. PubMed PMID:
20697016.
Gowrisankaran S, Anastasakis A, Fishman GA, Alexander
KR. Structural and functional measures of inner retinal
integrity following visual acuity improvement in a patient
with hereditary motor and sensory neuropathy type VI.
Ophthalmic Genet. 2011 Sep;32(3):188-92. Epub 2011 Jun
27. PubMed PMID: 21707411; PubMed Central PMCID:
PMC3155637.
Hoang QV, Qian H, Ripps H. Functional analysis of hemichannels and gap-junctional channels formed by connexins
43 and 46. Mol Vis. 2010 Jul 15;16:1343-52. PubMed PMID:
20664797; PubMed Central PMCID: PMC2905638.
Graeber CP, Gobin YP, Marr BP, Dunkel IJ, Brodie SE, Bornfeld N, Char DH, Folberg R, Imhof SM, Lin AY, Berry
JL, Al Mesfer S, Moll AC, Abramson DH. Histopathologic
findings of eyes enucleated after treatment with chemosurgery for retinoblastoma. Open Ophthalmol J. 2011 Jan
18;5:1-5. PubMed PMID: 21399766; PubMed Central PMCID:
PMC3052645.
Jabs DA, Ahuja A,Van Natta M, Lyon A, Srivastava S, Gangaputra S; Studies of the Ocular Complications of AIDS Research Group (Lim JI). Course of cytomegalovirus retinitis
in the era of highly active antiretroviral therapy: five-year
outcomes. Ophthalmology. 2010 Nov;117(11):2152-61.e1-2.
Epub 2010 Jul 29. PubMed PMID: 20673591; PubMed Central
PMCID: PMC2963687.
Jayaprakash PA, Edward DP, Wong M, Ravichandran P, Goldstein DA. The role of perivascular melanophage infiltrates
in the conjunctiva in sympathetic ophthalmia. Ocul.Immunol.
Inflamm. 2011;19:186-191.
Joy A, Mohammed TA, Al-Ghoul KJ. Abnormal fiber end
migration in Royal College of Surgeons rats during posterior
subcapsular cataract formation. Mol Vis. 2010 Jul 31;16:145366. PubMed PMID: 20806082; PubMed Central PMCID:
PMC2925909.
Karasneh GA, Ali M, Shukla D. An Important Role for Syndecan-1 in Herpes Simplex Virus Type-1 Induced Cell-to-Cell
Fusion and Virus Spread. PLoS One. 2011;6(9):e25252. Epub
2011 Sep 21. PubMed PMID: 21957484; PubMed Central
PMCID: PMC3177890.
Kiernan DF, Al-Heeti O, Blair MP, Keenan JD, Lichtenstein
SJ, Tsilou ET, Smaoui N, Shapiro MJ. Peripheral retinal nonperfusion in septo-optic dysplasia (de Morsier syndrome).
Arch Ophthalmol. 2011 May;129(5):671-3. PubMed PMID:
21555628.
Kiernan DF, Blair MP, Shapiro MJ. In utero diagnosis
of Norrie disease and early laser preserves visual acuity.
Arch Ophthalmol. 2010 Oct;128(10):1382. PubMed PMID:
20938020.
Kiernan DF, Blair MP, Shapiro MJ. Neovascularization after nonaccidental trauma. Ophthalmology. 2010
Dec;117(12):2443.e1-2. PubMed PMID: 21129574.
Kiernan DF, Hariprasad SM, Rusu IM, Mehta SV, Mieler
WF, Jager RD. Epidemiology of the association between
anticoagulants and intraocular hemorrhage in patients with
neovascular age-related macular degeneration. Retina. 2010
Nov-Dec;30(10):1573-8. PubMed PMID: 21060269.
Kiernan DF, Ksiazek SM, Jampol LM, Grassi MA. Photoreceptor Attenuation in Acute Zonal Occult Outer Retinopathy. Retinal Cases and Brief Reports, Fall 2010,4(4):339-345.
Kiernan DF, Mieler WF, Hariprasad SM.Variety, variability
and veracity: macular thickness and reproducibility among
optical coherence tomography systems. Am J Ophthalmol.
2010 Aug;150(2):138-140.e2. PubMed PMID: 20670737.
Kiernan DF, Shah RJ, Hariprasad SM, Grassi MA, Small KW,
Kiernan JP, Mieler WF. Thirty-Year follow-up of an AfricanAmerican family with macular dystrophy of the retina, locus
1 (North Carolina macular dystrophy). Ophthalmology.
2011 Jul;118(7):1435-43. Epub 2011 Feb 18. PubMed PMID:
21310494.
Kim BM, Shapiro MJ, Miller MT, Blair MP. Peripapillary
Staphyloma With Associated Retinopathy of Prematurity.
Retinal Cases and Brief Reports, Spring 2011,5(2):146-148.
Krakauer M, Aakalu VK, Davis PL, Ahmad AZ. Silicone
Spacer Repair of Medial Rectus After Iatrogenic Orbit Fracture. Ophthal Plast Reconstr Surg. 2011 Jun 21. [Epub ahead
of print] PubMed PMID: 21697756.
Li SY, Birnbaum AD, Goldstein DA. Optic neuritis associated with adalimumab in the treatment of uveitis. Ocul
Immunol Inflamm. 2010 Dec;18(6):475-81. Epub 2010 Sep 1.
Review. PubMed PMID: 20809867.
Lim JI, Fung AE, Wieland M, Hung D, Wong V. Sustainedrelease intravitreal liquid drug delivery using triamcinolone
acetonide for cystoid macular edema in retinal vein occlusion. Ophthalmology. 2011 Jul;118(7):1416-22. Epub 2011
Mar 12. PubMed PMID: 21397950.
Bold: Faculty
Blue: Fellow
Green: Resident
7
Department of Ophthalmology & Visual Sciences | Treating the most serious and complicated ophthalmology cases for over 150 years
Lim JI, Spee C, Hinton DR. A comparison of hypoxiainducible factor-α in surgically excised neovascular membranes of patients with diabetes compared with idiopathic
epiretinal membranes in nondiabetic patients. Retina. 2010
Oct;30(9):1472-8. PubMed PMID: 20811317.
Loduca AL, Zhang C, Zelkha R, Shahidi M. Thickness mapping of retinal layers by spectral-domain optical coherence
tomography. Am J Ophthalmol. 2010 Dec;150(6):849-55.
Epub 2010 Oct 16. PubMed PMID: 20951975; PubMed Central PMCID: PMC2991435.
Mahdi N, Faia LJ, Goodwin J, Nussenblatt RB, Nida Sen H.
A case of autoimmune retinopathy associated with thyroid
carcinoma. Ocul.Immunol.Inflamm. 2010;18:322-323.
Marcet MM, Setabutr P, Lemke BN, Collins ME, Fleming JC, Wesley RE, Pinto JM, Putterman AM. Surgical microanatomy of the müller muscle-conjunctival resection
ptosis procedure. Ophthal Plast Reconstr Surg. 2010 SepOct;26(5):360-4. PubMed PMID: 20622700.
Marmor MF, Kellner U, Lai TY, Lyons JS, Mieler WF; American Academy of Ophthalmology. Revised recommendations
on screening for chloroquine and hydroxychloroquine retinopathy. Ophthalmology. 2011 Feb;118(2):415-22. PubMed
PMID: 21292109.
McAnany JJ, Shahidi M, Applegate RA, Zelkha R, Alexander KR. Contributions of optical and non-optical blur to
variation in visual acuity. Optom Vis Sci. 2011 Jun;88(6):71623. PubMed PMID: 21460756; PubMed Central PMCID:
PMC3100362.
McAnany JJ, Alexander KR. Spatial contrast sensitivity in
dynamic and static additive luminance noise.Vision Res. 2010
Sep 15;50(19):1957-65. Epub 2010 Jul 16. PubMed PMID:
20638404; PubMed Central PMCID: PMC2926298.
Memic A,Volgina VV, Gussin HA, Pepperberg DR, Kay BK.
Generation of recombinant guinea pig antibody fragments
to the human GABAC receptor. J Immunol Methods. 2011
May 31;368(1-2):36-44. Epub 2011 Feb 26. PubMed PMID:
21362428; PubMed Central PMCID: PMC3100176.
Nassiri N, Pandya HK, Djalilian AR. Limbal allograft
transplantation using fibrin glue. Arch Ophthalmol. 2011
Feb;129(2):218-22. PubMed PMID: 21320970.
Nguyen QD, Shah SM, Khwaja AA, Channa R, Hatef E, Do
DV, Boyer D, Heier JS, Abraham P, Thach AB, Lit ES, Foster
BS, Kruger E, Dugel P, Chang T, Das A, Ciulla TA, Pollack JS,
Lim JI, Eliott D, Campochiaro PA; READ-2 Study Group.
Two-year outcomes of the ranibizumab for edema of the
macula in diabetes (READ-2) study. Ophthalmology. 2010
Nov;117(11):2146-51. Epub 2010 Sep 19. Erratum in: Ophthalmology. 2011 Jun;118(6):1016. Eliot, Dean [corrected to
Eliott, Dean]. PubMed PMID: 20855114.
Park B,Ying H, Shen X, Park JS, Qiu Y, Shyam R, Yue BY.
Impairment of protein trafficking upon overexpression and
mutation of optineurin. PLoS One. 2010 Jul 12;5(7):e11547.
PubMed PMID: 20634958; PubMed Central PMCID:
PMC2902519.
Patil AJ, Edward DP, Wong M, Ravichandran P, Goldstein DA.
The role of perivascular melanophage infiltrates in the conjunctiva in sympathetic ophthalmia. Ocul Immunol Inflamm.
2011 Jun;19(3):186-91. PubMed PMID: 21595534.
Pham M, Chow CC, Badawi D,Tu EY. Use of infliximab
in the treatment of peripheral ulcerative keratitis in Crohn
disease. Am J Ophthalmol. 2011 Aug;152(2):183-188.e2. Epub
2011 Jun 8. PubMed PMID: 21652024.
8
Pineles SL, Avery RA, Moss HE, Finkel R, Blinman T, Kaiser
L, Liu GT.Visual and systemic outcomes in pediatric ocular
myasthenia gravis. Am J Ophthalmol. 2010 Oct;150(4):453459.e3. Epub 2010 Aug 1. PubMed PMID: 20678749.
Puhan MA,Van Natta ML, Palella FJ, Addessi A, Meinert C;
Ocular Complications of AIDS Research Group (Lim JI).
Excess mortality in patients with AIDS in the era of highly
active antiretroviral therapy: temporal changes and risk
factors. Clin Infect Dis. 2010 Oct 15;51(8):947-56. PubMed
PMID: 20825306; PubMed Central PMCID: PMC2943970.
Pula JH, Towle VL, Staszak VM, Cao D, Bernard JT, Gomez
CM. Retinal Nerve Fibre Layer and Macular Thinning in
Spinocerebellar Ataxia and Cerebellar Multisystem Atrophy.
Neuroophthalmology. 2011 Jun;35(3):108-114. PubMed
PMID: 21866205; PubMed Central PMCID: PMC3159168.
Putterman AM. Instilling ocular ointments without
blurred vision. Ophthal Plast Reconstr Surg. 2010 NovDec;26(6):503. PubMed PMID: 20811310.
Qian H, Ripps H. Neurovascular interaction and the
pathophysiology of diabetic retinopathy. Exp Diabetes
Res. 2011;2011:693426. Epub 2011 Feb 21. PubMed PMID:
21747832; PubMed Central PMCID: PMC3124285.
Qian H, Alexander KR, Ripps H. Harmonic analysis
of the cone flicker ERG of rabbit. Exp Eye Res. 2010
Dec;91(6):811-7. Epub 2010 Oct 23. PubMed PMID:
20974130; PubMed Central PMCID: PMC2996095.
Roberts DK, Lukic A,Yang Y, Wilensky JT, Wernick MN.
Multispectral Diagnostic Imaging of the Iris in Pigment Dispersion Syndrome. J Glaucoma. 2011 Mar 16. [Epub ahead
of print] PubMed PMID: 21423031; PubMed Central PMCID:
PMC3153570.
Rowan MJ, Ripps H, Shen W. Fast glutamate uptake via
EAAT2 shapes the cone-mediated light offset response
in bipolar cells. J Physiol. 2010 Oct 15;588(Pt 20):394356. PubMed PMID: 20807794; PubMed Central PMCID:
PMC3000584.
Rush RB, Goldstein DA, Callanan DG, Meghpara B, Feuer
WJ, Davis JL. Outcomes of birdshot chorioretinopathy
treated with an intravitreal sustained-release fluocinolone acetonide-containing device. Am J Ophthalmol. 2011
Apr;151(4):630-6. Epub 2011 Feb 1. PubMed PMID:
21277557.
Sapitro J, Dunmire JJ, Scott SE, Sutariya V, Geldenhuys WJ,
Hewit M, Yue BY, Nakamura H. Suppression of transforming growth factor-β effects in rabbit subconjunctival
fibroblasts by activin receptor-like kinase 5 inhibitor. Mol Vis.
2010 Sep 16;16:1880-92. PubMed PMID: 21031133; PubMed
Central PMCID: PMC2956700.
Saraiya NV, Goldstein DA. Dexamethasone for
ocular inflammation. Expert Opin Pharmacother. 2011
May;12(7):1127-31. Epub 2011 Apr 2. PubMed PMID:
21457057.
Sen HN, Sangave AA, Goldstein DA, Suhler EB, Cunningham D,Vitale S, Nussenblatt RB. A standardized grading
system for scleritis. Ophthalmology. 2011 Apr;118(4):768-71.
Epub 2010 Nov 20. PubMed PMID: 21093921; PubMed Central PMCID: PMC3070789.
Sepahdari AR, Aakalu VK, Setabutr P, Shiehmorteza M, Naheedy JH, Mafee MF. Indeterminate orbital masses: restricted
diffusion at MR imaging with echo-planar diffusion-weighted
imaging predicts malignancy. Radiology. 2010 Aug;256(2):55464. PubMed PMID: 20656840.
Sezgin E, van Natta ML, Ahuja A, Lyon A, Srivastava S, Troyer
JL, O’Brien SJ, Jabs DA; Studies of the Ocular Complications of AIDS Research Group (Lim JI). Association of host
genetic risk factors with the course of cytomegalovirus retinitis in patients infected with human immunodeficiency virus.
Am J Ophthalmol. 2011 Jun;151(6):999-1006.e4. Epub 2011
Mar 10. PubMed PMID: 21396623; PubMed Central PMCID:
PMC3103625.
Shah A, Farooq AV, Tiwari V, Kim MJ, Shukla D. HSV-1 infection of human corneal epithelial cells: receptor-mediated entry and trends of re-infection. Mol Vis. 2010 Nov 20;16:247686. PubMed PMID: 21139972; PubMed Central PMCID:
PMC2994737.
Shahidi M, Wanek J, Blair NP, Little DM, Wu T. Retinal
tissue oxygen tension imaging in the rat. Invest Ophthalmol
Vis Sci. 2010 Sep;51(9):4766-70. Epub 2010 Apr 7. PubMed
PMID: 20375336; PubMed Central PMCID: PMC2941162.
Shapiro MJ, Chow CC, Karth PA, Kiernan DF, Blair MP.
Effects of green diode laser in the treatment of pediatric
Coats disease. Am J Ophthalmol. 2011 Apr;151(4):725-731.
e2. Epub 2011 Jan 22. PubMed PMID: 21257148.
Shen X,Ying H, Qiu Y, Park JS, Shyam R, Chi ZL, Iwata T, Yue
BY. Processing of optineurin in neuronal cells. J Biol Chem.
2011 Feb 4;286(5):3618-29. Epub 2010 Nov 8. PubMed
PMID: 21059646; PubMed Central PMCID: PMC3030366.
Taneri S, Oehler S, Azar DT. Influence of mydriatic
eye drops on wavefront sensing with the Zywave aberrometer. J Refract Surg. 2011 Sep;27(9):678-85. doi:
10.3928/1081597X-20110317-01. Epub 2011 Mar 31.
PubMed PMID: 21446641.
Taneri S, Weisberg M, Azar DT. Surface ablation techniques.
J Cataract Refract Surg. 2011 Feb;37(2):392-408. Review.
PubMed PMID: 21241926.
Thobani A, Anastasakis A, Fishman GA. Microperimetry
and OCT findings in female carriers of choroideremia.
Ophthalmic Genet. 2010 Dec;31(4):235-9. PubMed PMID:
21067487.
Thobani A, Fishman GA, Genead M, Anastasakis A.Visual
acuity loss in recessive retinitis pigmentosa and its correlation with macular lesions. Retina. 2011 May;31(5):967-72.
PubMed PMID: 21252818.
Thobani A, Fishman GA. The use of carbonic anhydrase
inhibitors in the retreatment of cystic macular lesions in
retinitis pigmentosa and X-linked retinoschisis. Retina. 2011
Feb;31(2):312-5. PubMed PMID: 20966823.
Tiwari V, Liu J,Valyi-Nagy T, Shukla D. Anti-heparan sulfate
peptides that block herpes simplex virus infection in vivo. J
Biol Chem. 2011 Jul 15;286(28):25406-15. Epub 2011 May
19. PubMed PMID: 21596749; PubMed Central PMCID:
PMC3137111.
Tiwari V, Darmani NA, Yue BY, Shukla D. In vitro antiviral
activity of neem (Azardirachta indica L.) bark extract against
herpes simplex virus type-1 infection. Phytother Res. 2010
Aug;24(8):1132-40. PubMed PMID: 20041417.
Tiwari V, Shukla D. Phosphoinositide 3 kinase signalling
may affect multiple steps during herpes simplex virus type-1
entry. J Gen Virol. 2010 Dec;91(Pt 12):3002-9. Epub 2010
Sep 1. PubMed PMID: 20810749; PubMed Central PMCID:
PMC3052565.
Traish AS, Chodosh J. Expanding application of the Boston type I keratoprosthesis due to advances in design and
improved post-operative therapeutic strategies. Semin
Ophthalmol. 2010 Sep-Nov;25(5-6):239-43. Review. PubMed
PMID: 21091006.
Tu EY, Joslin CE, Shoff ME. Successful treatment of chronic
stromal acanthamoeba keratitis with oral voriconazole
monotherapy. Cornea. 2010 Sep;29(9):1066-8. PubMed
PMID: 20539217; PubMed Central PMCID: PMC2926250.
Tu EY, Joslin CE. Recent outbreaks of atypical contact
lens-related keratitis: what have we learned? Am J Ophthalmol. 2010 Nov;150(5):602-608.e2. PubMed PMID: 21036209;
PubMed Central PMCID: PMC2991148.
Turturro SB, Guthrie MJ, Appel AA, Drapala PW, Brey
EM, Pérez-Luna VH, Mieler WF, Kang-Mieler JJ. The effects of cross-linked thermo-responsive PNIPAAm-based
hydrogel injection on retinal function. Biomaterials. 2011
May;32(14):3620-6. Epub 2011 Feb 12. PubMed PMID:
21320724.
Vajaranant TS, Anderson RJ, Zelkha R, Zhang C, Wilensky JT, Edward DP, Shahidi M. The relationship between
macular cell layer thickness and visual function in different
stages of glaucoma. Eye (Lond). 2011 May;25(5):612-8. Epub
2011 Feb 25. PubMed PMID: 21350568; PubMed Central
PMCID: PMC3093432.
Vajaranant TS, Blair MP, McMahon T, Wilensky JT, de
la Cruz J. Special considerations for pars plana tube-shunt
placement in Boston type 1 keratoprosthesis. Arch Ophthalmol. 2010 Nov;128(11):1480-2. PubMed PMID: 21060051.
Vasaiwala R, Sajja K, Setabutr P. Novel Management of the
Microphthalmic Orbit in a Patient With PHACE Syndrome.
Ophthal Plast Reconstr Surg. 2011 May 27. [Epub ahead of
print] PubMed PMID: 21629142.
Vasconcelos-Santos DV, Lim JI, Rao NA. Chronic coccidioidomycosis endophthalmitis without concomitant systemic
involvement: a clinicopathological case report. Ophthalmology. 2010 Sep;117(9):1839-42. Epub 2010 May 14. PubMed
PMID: 20471688; PubMed Central PMCID: PMC2933969.
Velez-Montoya R, Rascón-Vargas D, Mieler WF, FromowGuerra J, Morales-Cantón V. Intravitreal Ampicillin Sodium
for Antibiotic-Resistant Endophthalmitis: Streptococcus
uberis First Human Intraocular Infection Report. J Ophthalmol. 2010;2010. pii: 169739. Epub 2010 Jul 14. PubMed PMID:
20706679; PubMed Central PMCID: PMC2913728.
Venneti S, Moss HE, Levin MH,Vagefi MR, Brozena SC,
Pruitt AA, Mourelatos Z, Trojanowski JQ, Galetta SL, Balcer
LJ. Asymmetric bilateral demyelinating optic neuropathy from
tacrolimus toxicity. J Neurol Sci. 2011 Feb 15;301(1-2):112-5.
Epub 2010 Nov 26. PubMed PMID: 21112060.
Weisberg MP, Sugar J. Modalities to decrease stromal herpes simplex keratitis reactivation rates. Arch Ophthalmol.
2010 Nov;128(11):1497; author reply 1497-8. PubMed PMID:
21060060.
Winokur J, Lee J, Kumar G, Azar DT. Surgical technique of
femtosecond dovetail rotational autograft. Br J Ophthalmol.
2011 Mar;95(3):434-6. Epub 2010 Dec 13. PubMed PMID:
21156703.
Yeh SI, Han KY, Sabri A, Rosenblatt MI, Azar DT, Jain S,
Chang JH. MMP-7 knock-in corneal fibroblast cell lines
secrete MMP-7 with proteolytic activity towards collagen
XVIII. Curr Eye Res. 2010 Sep;35(9):799-805. PubMed PMID:
20795861.
Yue L, Xie A, Bruzik KS, Frølund B, Qian H, Pepperberg
DR. Potentiating action of propofol at GABAA receptors
of retinal bipolar cells. Invest Ophthalmol Vis Sci. 2011 Apr
16;52(5):2497-509. Print 2011 Apr. PubMed PMID: 21071744;
PubMed Central PMCID: PMC3088546.
Book Chapters 07/01/10 – 06/30/11
Krakauer M, Azar DT. Bacterial Keratitis. In: Melki SA, Fava
MA. Cornea and Refractive Atlas of Clinical Wisdom. Thorofare,
NJ: SLACK Inc., 2011.
Alio JL, Azar DT. Management of Complications in Refractive
Surgery. Gardners Books, 2010.
Lin A, Steinert RF. Intraoperative floppy iris syndrome. In:
Levin LA and Albert DM. Ocular Disease Mechanisms and
Management. [Philadelphia]: Saunders/Elsevier, 2010.
Birnbaum AD, Goldstein DA. Intermediate uveitis. In: Garg
SJ. Uveitis. Philadelphia: Wolters Kluwer Health/Lippincott
Williams & Wilkins, 2011.
Civelek ML, Saraiya N, Goldstein DA,Tessler HH. Hypersensitivity Uveitis. In: Duane TD, Tasman W, and Jaeger EA.
Duane’s Ophthalmology. Philadelphia: Lippincott Williams &
Wilkins, 2011. Internet resource.
Gilbert M, Goodwin JA. Neuro-ophthalmology of the
Afferent Visual System in Aging. In: Albert ML and Knoefel
JE. Clinical Neurology of Aging. New York: Oxford University
Press, 2011.
Goldstein DA. How do I diagnose and treat Fuchs Heterochromic Iridocyclitis. In: Foster S. Curbside Consultation in
Uveitis 49 Clinical Questions. SLACK Inc., 2011.
Goodwin JA. Leber’s Hereditary Optic Neuropathy. In: Neurobase. Arbor Publishing Co., Gilman S, Goldstein GW, and
Waxman SG, eds. First published in 1994, updated annually.
Goodwin JA. Orbital Inflammatory Pseudotumor and
Tolosa Hunt Syndrome. In: Neurobase. Arbor Publishing Co.,
Gilman S, Goldstein GW, and Waxman SG, eds. First published in 1994, updated annually.
Goodwin JA. Temporal Arteritis. In: Neurobase. Arbor Publishing Co., Gilman S, Goldstein GW, and Waxman SG, eds.
First published in 1994, updated annually.
Goodwin JA. Transient Visual Loss. In: Neurobase. Arbor
Publishing Co., Gilman S, Goldstein GW, and Waxman SG,
eds. First published in 1994, updated annually.
Goodwin JA.Vogt-Koyanagi-Harada Disease. In: Neurobase.
Arbor Publishing Co., Gilman S, Goldstein GW, and Waxman
SG, eds. [CD-ROM based computerized Textbook of Neurology] First published in 1994, updated annually.
Lin RC, Mieler WF, Wirostko WJ: Epiretinal Membrane. In:
Quiroz-Mercado H, Kerrison JB, Alfaro DV III, Mieler WF,
and Liggett PE, eds. Macular Surgery. Philadelphia: Wolters
Kluwer/Lippincott Williams & Wilkins Health, 2011.
Lin RC, Mieler WF. Retinal toxicity of systemic and topical
medications. In: Nguyen QD, Rodrigues EB, Farah, Eid M, and
Mieler WF, eds. Retinal Pharmacotherapy. [Maryland Heights,
MO]: Saunders/Elsevier, 2010.
Naithani R, Mehta RG, Shukla D, Chandersekera SN, Moriarty RM. Antiviral Activity of Phytochemicals: A Current
Perspective. In: Watson RR, Zibadi S, and Preedy VR. Dietary
Components and Immune Function. Totowa, NJ: Humana, 2010.
Nguyen QD, Rodrigues EB, Farah ME, and Mieler WF, eds.
Retinal Pharmacotherapy. [Maryland Heights, MO]: Saunders/
Elsevier, 2010.
Porter IW, Azar DT. Correction of astigmatism by laser
keratectomy. In: Henderson BA and Gills JP. A Complete Surgical Guide for Correcting Astigmatism: An Ophthalmic Manifesto.
Thorofare, NJ: SLACK Inc., 2011.
Putterman AM. Cheek midface lift. In: Levine MR. Manual
of Oculoplastic Surgery. Thorofare, NJ: SLACK Inc., 2010.
Putterman AM. Muller’s Muscle-Conjunctival Resection.
In: Levine MR. Manual of Oculoplastic Surgery. Thorofare, NJ:
SLACK Inc., 2010.
Quiroz-Mercado H, Kerrison JB, Alfaro DV III, Mieler WF,
Liggett PE, eds. Macular Surgery. Philadelphia: Wolters Kluwer/
Lippincott Williams & Wilkins Health, 2011.
Saraiya NY, Goldstein DA. Drug-induced uveitis. In: Garg SJ.
Uveitis. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins, 2011.
Goodwin, JA: Clinical Neuro-ophthalmology. In: MedLink
Neurology. San Diego, CA: MedLink Corp., 1990. <http://
www.medlink.com/user/MedLinkLogin.ASP>
Porter IW, Azar DT. Corneal Topography. In: Melki SA, Fava
MA. Cornea and Refractive Atlas of Clinical Wisdom. Thorofare,
NJ: SLACK Inc., 2011.
Hariprasad SM, Mieler WF. Antibiotics. In: Nguyen QD,
Rodrigues EB, Farah, Eid M, and Mieler WF, eds. Retinal
Pharmacotherapy. [Maryland Heights, MO]: Saunders/Elsevier,
2010.
Schmidt-Erfurth U, Williams GA, and Mieler WF. Encyclopedia of Ophthalmology. Berlin: Springer, 2011.
Kang-Mieler JJ, Kiernan DF, Mieler WF: Drug Delivery to
the Posterior Segment. In: Duane TD, Tasman W, and Jaeger
EA. Duane’s Ophthalmology. Philadelphia: Lippincott Williams
& Wilkins, 2011. Internet resource.
Kang-Mieler JJ, Mieler WF. Thermo-sensitive hydrogels. In:
Nguyen QD, Rodrigues EB, Farah, Eid M, and Mieler WF, eds.
Retinal Pharmacotherapy. [Maryland Heights, MO]: Saunders/
Elsevier, 2010.
Klesert TR, Lim JI. Anti-VEGF treatment for age-related
macular degeneration. In: Holz FG and Spaide RF. Medical
Retina. Berlin: Springer, 2010.
Knepper PA, Nolan MJ, Yue BYJT. CD44 and Primary
Open Angle Glaucoma. In: Schacknow PN and Samples JR.
The Glaucoma Book A Practical, Evidence-Based Approach to
Patient Care. New York: Springer, 2010.
Knepper PA, Nolan MJ, Yue BYJT. How the Revolution
in Cell Biology Will Affect Glaucoma: Biomarkers. In: Schacknow PN and Samples JR. The Glaucoma Book A Practical,
Evidence-Based Approach to Patient Care. New York: Springer,
2010.
Shukla SY, Kiernan DF, Lim JI. Role of anti-VEGF therapies in neovascular AMD: what the clinical trials tell us. In:
Campbell EJ and McMann LM. Macular Degeneration: Causes,
Diagnosis, and Treatment. Hauppauge, NY: Nova Science Publishers, 2010.
Tu EY. Fungal Keratitis. In: Melki SA, Fava MA. Cornea and
Refractive Atlas of Clinical Wisdom. Thorofare, NJ: SLACK Inc.,
2011.
Tu EY. Acanthamoeba Keratitis. In: Melki SA, Fava MA.
Cornea and Refractive Atlas of Clinical Wisdom. Thorofare, NJ:
SLACK Inc., 2011.
Viana MA, Wynn HP. Algebraic Methods in Statistics and
Probability II: AMS Special Session Algebraic Methods in Statistics
and Probability, March 27-29, 2009, University of Illinois at
Urbana-Champaign, Champaign, IL. Providence, RI: American
Mathematical Society, 2010.
Wong JJ, Azar DT. Stromal Dystrophies. In: Melki SA, Fava
MA. Cornea and Refractive Atlas of Clinical Wisdom. Thorofare,
NJ: SLACK Inc., 2011.
Bold: Faculty
Blue: Fellow
Green: Resident
9
Department of Ophthalmology & Visual Sciences | Treating the most serious and complicated ophthalmology cases for over 150 years
Wu C-W, Ellenberg D, Chang J-H. Corneal angiogenesis
and lymphangiogenesis. In: Levin LA and Albert DM. Ocular
Disease Mechanisms and Management. [Philadelphia]: Saunders/Elsevier, 2010.
Hsia YC, Leal SM, Booton GC, Joslin CE, Cianciotto NP, Tu
EY, Pearlman E. Acanthamoeba keratitis is exacerbated in
the presence of intracellular legionella pneumophila. ARVO
Meeting Abstracts 2011;52:5794.
Milani BY, Amirjamshidi H, Sagha H, Shafiq M, Movahedan A,
Lavker RM, Yue BY, Djalilian AR. Limbal fibroblast conditioned media: A non-invasive treatment for limbal stem cell
deficiency. ARVO Meeting Abstracts 2011;52:5144.
Yannuzzi LA, Ed., The Retinal Atlas, Benson WE, Freund KB,
Green WR, Hackel R, McDonald HR, Mieler WF, Shields
CL, Shields JA, Trese MT, Contributors. The Retinal Atlas.
[Philadelphia]: Saunders/Elsevier, 2010.
Hsu M, Nolan M, Lin A. Indications and outcomes of scleral
contact lens for severe ocular surface disease in the acute
inpatient setting. ARVO Meeting Abstracts 2011;52:1960.
Movahedan A, Djalilian AR, Lavker RM, Yue BY. Notch
activation and inhibition in corneal epithelial wound healing.
ARVO Meeting Abstracts 2011;52:2033.
Jivrajka RV, Shammas M, Shammas JH. Improving second eye
refractive error in patients undergoing cataract surgery.
ARVO Meeting Abstracts 2011;52:2790.
Namavari A, Chaudhary SV, Sarkar J,Yco L, Ma K, Jain S.
Nerve regeneration in murine cornea. ARVO Meeting Abstracts 2011;52:1972.
Joslin CE,Tu EY. Contemporary annualized incidence
rates of acanthamoeba keratitis. ARVO Meeting Abstracts
2011;52:1479.
Nayeb-Hashemi N, Patel S, Goldstein D. Anterior segment ocular coherence tomography in the evaluation of
scleral pathology. ARVO Meeting Abstracts 2011;52:1751.
Kang Mieler JJ, Jiang B, Perez-Luna V, Brey E, Mieler WF.
PLGA nanospheres encapsulated within thermo-responsive
hydrogel for ocular delivery of dexamethasone sodium
phosphate. ARVO Meeting Abstracts 2011;52:467.
Oltra EZ, Morris C, Birnbaum AD, Tessler HH, Goldstein
DA. Chronic granulomatous uveitis in common variable immunodeficiency. ARVO Meeting Abstracts 2011;52:4281.
ARVO Meeting Abstracts April 22, 2011
Al-Ghoul KJ, Williams DK. Secondary suture branch formation in rat lenses. ARVO Meeting Abstracts 2011;52:1537.
Bakhtiari P, Welder J, Chan C, de la Cruz J, Holland EJ, Djalilian AR. Surgical and visual outcomes of the type 1 Boston
keratoprosthesis for the management of aniridic fibrosis
syndrome in congenital aniridia. ARVO Meeting Abstracts
2011;52:332.
Cao D, Sun H, Lee BB. The weighting of rod and cone inputs
to primate magnocellular ganglion cells. ARVO Meeting Abstracts 2011;52:4568.
Chang Q, Grassi MA. Fas mediated extrinsic apoptotic
signaling in cone photoreceptors. ARVO Meeting Abstracts
2011;52:1811.
Cho JY, Hu J, Chau FY, Lim JI. Association of spectral
domain optical coherence tomography (SD-OCT) detected
focal retinal thinning with systemic complications of sickle
hemoglobinopathy. ARVO Meeting Abstracts 2011;52:1025.
Cortina MS, He J, Russ T, Bazan NG, Bazan HE. Topical
treatment with neuroprotectin D1 increases corneal nerve
regeneration after experimental surgery. ARVO Meeting
Abstracts 2011;52:1982.
Crary MJ, Narayanan S,Visvesvara G, Joslin C,Tu E, Panjwani N, Hopkins A, Booton G, Fuerst P. Genotyping acanthamoeba keratitis (AK) infections: Cytochrome oxidase I
(COI) barcoding and phylogenetic analysis. ARVO Meeting
Abstracts 2011;52:5832.
de la Cruz J, Cortina MS, Chang J, Azar DT. Scanning
electron microscopy analysis of explanted keratoprostheses.
ARVO Meeting Abstracts 2011;52:345.
Knepper PA, McCarty RD, Mayer JP, Schwartz SN, Nolan
MJ, Samples JR, Liebmann JM, Ritch R. Low molecular weight
hyaluronic acid in POAG aqueous. ARVO Meeting Abstracts
2011;52:4627.
Knighton EA, Zoltoski RK, Roberts DK, Wilensky JT,
Kuszak JR. Rate of increase in lens thickness decreases with
age. ARVO Meeting Abstracts 2011;52:1540.
Krakauer M, Gupta S, Farooq AV, de la Cruz J, Cortina
MS, Setabutr P. Oculoplastic considerations in keratoprosthesis surgery. ARVO Meeting Abstracts 2011;52:342.
Kwak J, Movahedan A, Tadjvidi P, Aref P, Maumenee IH.
Mendelian inheritance of strabismus in a rural community of
northern Iran. ARVO Meeting Abstracts 2011;52:6359.
Liu Y, Ripps H, Shen W. Localization of pannexin-mediated
electrical coupling in the amphibian retinal cone pathway.
ARVO Meeting Abstracts 2011;52:4556.
MajdiNasab M, Welder J, Pandya HK, Nassiri N, Djalilian
AR. Fibrin glue and conjunctival-limbal transplant. ARVO
Meeting Abstracts 2011;52:5136.
Do DV, Nguyen QD, Khwaja AA, Channa R, Sepah YJ, Boyer
DS, Heier JS, Lim JI, Campochiaro PA, READ 2 Study Group.
Aggressive anti-VEGF treatment is necessary to control diabetic macular edema in many patients: Month 36 outcomes
of the READ2 trial. ARVO Meeting Abstracts 2011;52:5332.
Malchow RP, Jacoby J, Booth SE, Alford ST, Qian H, Kreitzer
MA. Testing the H+ hypothesis of feedback inhibition from
horizontal cells to vertebrate photoreceptors: A tale of two
techniques. ARVO Meeting Abstracts 2011;52:2568.
Ebihara L, Tong J, Chen T, Minogue PJ, Berthoud VM, Beyer
EC. Different dominant effects of two cataract associated
Cx50 mutants. ARVO Meeting Abstracts 2011;52:805.
Maumenee IH, Alharbi AF,Yanoga F, Azar NF. Natural
history, genotype-phenotype correlation and differential
diagnosis of the brittle cornea syndrome. ARVO Meeting
Abstracts 2011;52:2397.
Genead MA, Fishman GA. Presence and treatment of cystoid macular edema in patients with choroideremia. ARVO
Meeting Abstracts 2011;52:2130.
Grant P, Wanek JM, Zelkha R, Lim JI, Shahidi M. Wavefront
aberration and fixation variations in normal subjects. ARVO
Meeting Abstracts 2011;52:4460.
Han KY, Chang J, Azar DT. Characterization of vegf-c
induced lymphatic endothelial cell signaling by bioelectrical
impedance analysis. ARVO Meeting Abstracts 2011;52:4827.
10
Kiernan DF, Chow CC, Singh R, Ulanski LJ, Lim JI, Blair
NP, Mieler WF. Subsequent intravitreal triamcinolone is an
effective treatment for I-125 plaque-associated retinopathy
recalcitrant to intravitreal bevacizumab. ARVO Meeting Abstracts 2011;52:2105.
Mayer JP, Kasniunas A, McCarty RD, Schwartz SN, Yue BYJT,
Knepper PA. Toll-like receptor 4, low molecular weight hyaluronic acid and cytokine response in trabecular meshwork
cells. ARVO Meeting Abstracts 2011;52:4652.
McCarty RD, Mayer JP, Schwartz SN, Knepper PA. Endogeneous hyaluronidase and hyaluronidase inhibitors in POAG
aqueous. ARVO Meeting Abstracts 2011;52:2430.
Mieler WF, Appel A, Turturro SB, Jiang B, Perez-Luna V,
Brey E, Kang Mieler JJ. Efficacy of dexamethasone sodium
phosphate thermo-responsive hydrogel treatment in
endotoxin-induced uveitis model. ARVO Meeting Abstracts
2011;52:2752.
Ostheimer TA, de la Cruz J, Cortina MS. Corneal graft
thinning in Boston type 1 keratoprosthesis patients. ARVO
Meeting Abstracts 2011;52:346.
Ozturk O, Ghanem RC, Han KY, Rojas J, Kim DJ, Chang J,
Azar DT. Semaphorin 7a promotes macrophage recruitment and angigenesis in experimental corneal neovascularization model. ARVO Meeting Abstracts 2011;52:6394.
Rha J, Genead MA, Bonci DM, Dubis AM, Schroeder B, Neitz
M, Fishman GA, Carroll J. Imaging photoreceptor structure
in achromatopsia patients using adaptive optics and spectral
-domain optical coherence tomography. ARVO Meeting Abstracts 2011;52:4897.
Riaz KM, Djalilian AR, Bakhtiari P, Basti S. Natural course
and treatment outcomes for limbal niche dysfunction. ARVO
Meeting Abstracts 2011;52:5120.
Roberts DK, Ayyagari R, McCarthy BJ, Xie H, Wilensky
JT, Davis F. Case-control study of long anterior lens zonule
(LAZ) trait in first-degree relatives of African-American probands. ARVO Meeting Abstracts 2011;52:2800.
Rose-Nussbaumer J, Goldstein DA, Acharya NR, Thorne
JE, Shakoor A,Yeh S, Rahman H, Flaxel CJ, Smith JR. Uveitis in
immunocompetent persons infected with human immunodeficiency virus (HIV). ARVO Meeting Abstracts 2011;52:4274.
Schwartz SN, Beverley RM, Giovingo MC, McCarty RD, Mayer JP, Knepper PA. Actin reorganization (CLANs) induced
by sCD44-treatment in trabecular meshwork cells. ARVO
Meeting Abstracts 2011;52:4634.
Sen HN, Drye LT, Goldstein DA, Larson TA, Merrill PT, Pavan PR, Sheppard JD, Burke A, Srivastava SK, Jabs DA. Hypotony in patients with uveitis: The multicenter uveitis steroid
treatment trial. ARVO Meeting Abstracts 2011;52:4269.
Shafiq MA, Gemeinhart RA,Yue BY, Djalilian AR. Development of an acellular human cornea to support the
growth of corneal epithelial and stromal cells. ARVO Meeting
Abstracts 2011;52:296.
Shah RJ, Chow CC, Hallak JA, Lim JI,Vajaranant TS. Retinal nerve fiber layer (RNFL) thickness analysis in sickle cell
disease: Implications for glaucoma evaluation. ARVO Meeting
Abstracts 2011;52:248.
Shahidi M, Wanek JM, Zelkha R. Enface imaging of photoreceptor cell integrity. ARVO Meeting Abstracts 2011;52:2877.
Shukla D, Karasneh G, Bacsa S,Valyi-Nagy T. Up-regulation
of syndecan expression may be A viral-induced mechanism
for HSV-1 shedding. ARVO Meeting Abstracts 2011;52:5866.
Singa RM, Aakalu VK, Lin A, Setabutr P, Jain S. Accessory lacrimal tissue gene expression. ARVO Meeting
Abstracts 2011;52:5993.
Souteyrand G, Prat C, Yue B, Sapin V, Chiambaretta F. The
beta-isoform of vitamin A receptors are expressed in human corneal endothelium and epithelium. ARVO Meeting
Abstracts 2011;52:6698.
Srivastava SK, Nguyen QD, Callanan D, Goldstein DA,
Albini TA. The use of the fluocinolone acetonide (retisert)
implant in patients with birdshot choroidopathy. ARVO
Meeting Abstracts 2011;52:2751.
Thomas JG, Selner AN, Hetling JR. Exogenous currents
delivered to the eye as A potential therapy: Computational model comparing two electrode geometries in rat.
ARVO Meeting Abstracts 2011;52:1864.
Tshionyi M, Shay E, Lunde E, Lin A, Han K, Jain S, Chang
J, Azar D. Prevalence and distribution of hemangiogenesis and lymphangiogenesis in pathologic corneas. ARVO
Meeting Abstracts 2011;52:2017.
Tu EY, Shoff ME, Joslin CE. The addition of benzalkonium chloride to moxifloxacin confers anti-acanthamoebal
activity in an in vitro model. ARVO Meeting Abstracts
2011;52:5830.
Vajaranant TS, Wu S, Torres M,Varma R. Demographic
and geographic changes in the burden of visual impairment and blindness in the United States: 2010-2050.
ARVO Meeting Abstracts 2011;52:4220.
Wanek JM, Teng P, Blair NP, Shahidi M. A new imaging
method for assessment of inner retinal oxygen consumption in rat. ARVO Meeting Abstracts 2011;52:1348.
Wang AL, Grassi MA. Role of FAM18B in diabetic retinopathy. ARVO Meeting Abstracts 2011;52:2579.
Xie A, Pawlowski M, Feng F, Bruzik KS, Qian H, Pepperberg DR. Enhancement of GABA-elicited responses of
retinal ganglion cells by A photo-isomerizable compound.
ARVO Meeting Abstracts 2011;52:1610.
Yco L, Namavari A, Chaudhary SV, Sarkar J, Jain S. Proteomic analysis of murine corneas during nerve regeneration. ARVO Meeting Abstracts 2011;52:2016.
Ying H, Qiu Y, Shen X, Shyam R, Yue BYJT. Establishment of inducible wild type and mutant myocilin-GFPexpressing RGC5 cell lines. ARVO Meeting Abstracts
2011;52:4597.
Yue L, Pawlowski M, Bruzik KS, Qian H, Pepperberg
DR. Photo-regulated activity of A tethered propofol
derivative at GABAA receptors. ARVO Meeting Abstracts
2011;52:1166.
Bold: Faculty
Blue: Fellow
Green: Resident
ER
ILV F
Teng P, Blair NP, Wanek JM,Yildirim I, Shahidi M. Longitudinal gradients of oxygen tension in the retinal vasculature of rat. ARVO Meeting Abstracts 2011;52:1732.
ELL O W
ARVO
S
Suhler EB, Lowder CY, Goldstein DA, Giles TR, Tessler HH, Lauer AK, Smith JR, Rosenbaum JT. Adalimumab
(humira) for the treatment of refractory sight-threatening
non-infectious uveitis: One year outcomes of an openlabel prospective multicenter study. ARVO Meeting Abstracts 2011;52:6565.
(Standing): David Pepperberg, PhD; Nalin Kumar, DPhil; Deepak Shukla, PhD;
(Seated):Beatrice Yue, PhD; Ken Alexander, PhD; and Mahnaz Shahidi, PhD
Dr. Kenneth Alexander Retires
Spanning 30 years, the esteemed vision scientist’s UIC
career includes important research, service and mentoring
Congratulations to Kenneth Alexander, PhD, Professor of Ophthalmology and Visual
Sciences, who retired on November 15. Dr. Alexander leaves UIC with a legacy of important
accomplishments in the three facets of academic life: teaching, research and service.
As an outstanding scientist, Dr. Alexander regards his greatest research achievement as clarifying
the pathophysiology of inherited and acquired retinal diseases through research funded for 27
years by the National Eye Institute, National Institutes of Health (NIH). The impressive list
of papers he has authored (more than 120 original articles in peer-reviewed publications) is
evidence of a career dedicated to improving patient care through research. Dr. Alexander’s
interest in developing noninvasive tests for assessing visual function was fostered during his 30
years of collaboration at UIC with Gerald Fishman, MD, a world-renowned authority on retinal
disorders who was formerly Director of the Electrophysiology Service in UIC’s Department
of Ophthalmology and Visual Sciences, and currently serves as Director of the Pangere Center
for Inherited Retinal Diseases at the Chicago Lighthouse for People Who Are Blind or Visually
Impaired.
An important mentor for Dr. Alexander, as he pursued his PhD in Psychology at the University
of Washington, was the late Davida Teller, PhD, a pioneer in the study of infant vision. He also
conducted research as an NIH Postdoctoral Research Fellow under the mentorship of Ralph
Norman Haber, PhD, a leader in the psychology of visual perception, at the Center for Visual
Science, University of Rochester.
Dr. Alexander held a faculty appointment at the Illinois College of Optometry and also taught
part-time at the Art Institute of Chicago and DePaul University before joining UIC in 1981 as a
Research Assistant Professor in the Department of Ophthalmology and Visual Sciences. He was
promoted to Associate Professor in 1987 and to full Professor in 1994. In 2002 he was named
the Marion H. Schenk, Esq. Professor of Ophthalmology and Visual Sciences. Dr. Alexander also
held two adjunct appointments at UIC in the Department of Psychology and in the Department
of Bioengineering, illustrating the multidisciplinary nature of his research.
Dr. Alexander has also been an exceptional mentor and teacher throughout his career, guiding
the careers of eight postdoctoral fellows, among them Neal Peachey, PhD, Professor at the
Cole Eye Institute; Janet Szlyk, PhD, Executive Director of the Chicago Lighthouse; and Jason
McAnany, PhD, Assistant Professor in UIC’s Department of Ophthalmology and Visual Sciences.
Dr. Alexander has been committed to academic service at UIC and throughout the vision
science community. He is honored to have served as a regular member of the Biology of the
Posterior Eye (BDPE) Study Section of the NIH and is proud of his leadership role in the Optical
Society of America, including service as Chair of the Noninvasive Assessment of Visual Function
Topical Meeting and Chair of the Division of Vision and Color.
Dr. Alexander is also a member of Phi Beta Kappa and Sigma Xi, a Fellow of the Optical Society
of America, and an ARVO Silver Fellow.
11
Department of Ophthalmology & Visual Sciences | Treating the most serious and complicated ophthalmology cases for over 150 years
UIC Receives Prestigious
NEI K12 Grant
Dr. Dimitri Azar to serve as Principal Investigator
The National Eye Institute (NEI) of the National Institutes of
Health has awarded UIC a $2.5 million grant for the UIC-NEI K12
Independent Clinical Vision Scientist Development Program. The
project began in September and will continue through August 2016
under the leadership of Dr. Dimitri Azar, principal investigator for
the project. UIC’s first-ever “K12 class” includes three MD, PhDs: Dr.
Heather Moss, Assistant Professor of Ophthalmology and Director of
the Neuro-Ophthalmology Research Program; Dr. Yannek Leiderman,
Director of the Retinal Bank Laboratory; and Dr. Iris Kassem,
Assistant Professor of Ophthalmology in Pediatric Ophthalmology &
Adult Strabismus Service.
UIC’s program has two goals: to establish a public university-public
health agency partnership to train independent clinician vision
scientists; and to provide scientific development, authentic mentorship
and the professional development of the K12 scholars to ensure their
transition to independence. Achievement of these goals will enable
program scholars to become national leaders in vision health research,
as well as the educators, mentors and role models for a new generation
of vision health researchers.
The NEI’s program goal is to develop highly trained clinical scientists
and patient-oriented investigators to address the nation’s biomedical,
behavioral and clinical research needs in vision research. In turn, UIC
has provided an academically rich and supportive environment that
gives qualified early-stage clinician vision scientists a mentored learning
experience to facilitate their career advancement and help them to
become independent scientists. UIC is one of seven leading institutions
in the U.S. operating a K12 program. The others include Duke
University, John Hopkins University, the University of Pennsylvania,
Washington University, Massachusetts Eye and Ear Infirmary, and
University of California, Berkeley.
Dr. Moss is currently working on two projects as part of the K12
program. “I am continuing work that I started during my fellowship
which demonstrated that vision is decreased in amyotrophic lateral
sclerosis (ALS),” says Dr. Moss. “This is a devastating neurodegenerative disease not previously thought to affect the visual
pathways. The primary aims of this project are to determine why vision
is decreased and if this decrease affects vision-related quality of life.” Translational research in vision science has become a top priority
in the recruitment of faculty, the development of junior faculty into
independent scientists, and in setting goals for the Department of
Ophthalmology and Visual Sciences’ research program. According
to Dr. Azar, the K12 program leverages the nascent success of the
department in launching clinician scientist careers by building the
positive resources already present in the department and strengthening
them through development of a K12 curriculum mentored by leading
scholars and researchers.
“One of the reasons we decided to pursue a K12
program was the growing number of faculty who
benefited from our research resources to successfully
apply for their own K awards: Sandeep Jain, Ali Djalilian,
Charlotte Joslin and Deepak Shukla,” states Dr. Azar.
“We realized that we have an exceptional environment
for developing clinician scientists. Our proposal to NEI
expanded on this strong foundation.”
In addition, Dr. Moss is starting a new project focused on vision loss
due to the swelling of the optic disc in patients with high intracranial
pressure, known as papilledema. “The aim is to identify examination
and imaging markers that can predict the trajectory of vision (improving
or declining) in a given patient,” notes Dr. Moss. Dr. Moss sees definite career benefits in participating in the K12
program. “The grant is valuable because it will fund part of my salary
and therefore allow me to dedicate more time to research,” says Dr.
Moss. “This is especially important at this stage when I am starting
new research projects that are not yet funded. Having this grant will
springboard the projects and my career forward towards independent
funding.”
“This is especially important at this stage when I am starting new research projects
that are not yet funded. Having this grant will springboard the projects and my career
forward towards independent funding.” —Heather Moss, MD, PhD
UIC’s K12 training program has taken a needs-assessment approach
to identify and address the barriers to achieving independence that
confront clinicians who have demonstrated the skills needed to
become independent clinician scientists. The program recognizes that
research under the guidance of experienced mentors is key in order
for investigators to transition to independence. So, the Department
developed the K12 curriculum for mentoring scholars who have
demonstrated readiness to be immersed in a research project.
12
Heather Moss, MD, PhD
Dr. Moss also sees her work in the K12 program benefitting patients.
“My work with ALS patients may characterize a novel marker of
disease that could guide future research and therapies,” states Dr.
Moss. “And my work studying papilledema could help doctors (like
myself) to appropriately refine therapeutic strategies for treatment of
papilledema.”
UIC’s first “K12 Class” (L-R): Kassem, Moss and Leiderman
Yannek Leiderman, MD, PhD
Iris Kassem, MD, PhD
As part of the K12 program, Dr. Leiderman is researching retinal
detachment and new treatments for restoring patients’ vision. Retinal
detachment is a separation of the light-sensing structures from the
back of the eye, resulting in profound loss of vision. Microsurgical
techniques are utilized to restore the retina to its normal location.
In describing the pediatric eye research she is conducting as part of
the K12 program, Dr. Kassem explains, “A child’s eyes are not simply
a smaller version of an adult’s eyes. There are fundamental differences
in the structure and healing of the pediatric eye, as well as the
development of a child’s vision, that make them unique. I am interested
in elucidating these differences in pediatric eye disease and disorders
and applying them to the care of our patients.”
“The most significant impediment to restoring vision is scarring of the
retina, or proliferative vitreoretinopathy (PVR),” says Dr. Leiderman.
“My laboratory studies the chemical signals that promote the
formation of scar tissue following retinal detachment and eye trauma.
By identifying the chemical messengers that result in PVR, we hope to
discover new targets for medications that will block scar formation,
allowing for restoration of vision in the most severe cases of retinal
detachment.”
Vitreoretinal surgeons employ microsurgical techniques to restore
function to tissues and structures among the most delicate and
complex in the human body. Continual progress in understanding the
chemical signals that maintain and nourish the retina provides new
opportunities for restoring function and maintaining vision following
retinal detachment. “The K12 program at UIC allows me to harness
developments in laboratory research for continued progress in the
surgical and medical treatment of the most complex eye diseases,”
states Dr. Leiderman. Dr. Leiderman notes that the K12 grant provides the support
necessary to pursue laboratory investigations, as well as a framework
for mentoring and access to shared resources, which are critical to
establishing a successful research program and transitioning to an
independent investigator.
Dr. Kassem also stresses the important role that mentors play in the
K12 program. “I will have a mentor who is a successful clinician scientist,
which will help me to develop the skills I need to one day be able to
make my own contributions to advancing science and clinical care in
pediatric ophthalmology. The wealth of information and experience
my mentor has, not only in the science and techniques, but also in how
to develop a research plan and write successful publications and grant
applications, makes the program invaluable to my career development.”
Dr. Kassem’s ultimate goal in the K12 program is to bridge the gap
between basic science and medicine in pediatric eye care. “Developing
a greater understanding of the mechanisms involved in pediatric eye
problems will allow us to apply the knowledge to modify our therapies,
which can improve patient outcomes,” says Dr. Kassem. “If a child has
poor vision that goes uncorrected, it can result in a lifetime of visual
impairment. Conversely, if you fix a child’s vision, it can positively
impact them for their entire life. The grant gives me a great opportunity
to apply both the basic science and clinical aspects of my training to
discovering better ways to diagnose and treat the serious pediatric eye
problems I see in my patients.” 13
Department of Ophthalmology & Visual Sciences | Treating the most serious and complicated ophthalmology cases for over 150 years
PHYSICIANS
CLINICAL
FELLOWS
CORNEA
Roshni Vasaiwala, MD
RETINA
Clement Chow, MD
CORNEA
Priti Batta, MD
RETINA
Rajiv Rathod, MD
GLAUCOMA
Robert McGlynn, MD
OCULOPLASTIC
SURGERY
Vinay Aakalu, MD
PEDIATRIC
OPHTHALMOLOGY
Katherine Hare, MD
UVEITIS
Jose Maria GarciaGonzalez, MD
UVEITIS
Sarju Patel, MD
UVEITIS
Scott Steiner, MD
RESIDENTS
THIRD YEAR
Elizabeth Grace, MD
Jennifer Hu, MD
Mark Krakauer, MD,
DPhil
Neema Nayeb-Hashemi,
MD
Trucian Ostheimer, MD
Rohan Shah, MD
Kelly Bui, MD
Joshua Hou, MD
Sara Huh, MD
Renu Jivrajka, MD
Joann Kang, MD
Erica Oltra, MD
Janet Lim, MD
Randee Miller, MD
Senad Osmanovic, MD
Kevin Patel, MD
Adam Prickett, MD
Kavitha Sivaraman, MD
SECOND YEAR
FIRST YEAR
14
IN TRAINING
15
Department of Ophthalmology & Visual Sciences | Treating the most serious and complicated ophthalmology cases for over 150 years
SPONSORED RESEARCH
FEDERALLY SPONSORED RESEARCH
16
Investigator
Title
Source
Alexander, Kenneth, PhD
Visual Dysfunction in Retinal Degenerations
National Eye Institute
Azar, Dimitri, MD, MBA
Metalloproteinase Expression in Corneal Wound
National Eye Institute
Azar, Dimitri, MD, MBA
P30 Core Grant for Vision Research
National Eye Institute
Azar, Dimitri, MD, MBA
UIC K12 Independent Clinical Vision Scientist Development Program
National Eye Institute
Cao, Dingcai, PhD
Rod-cone Interactions in Mesopic Vision
National Eye Institute
Chang, Robert, PhD
Inhibition of VEGF Receptor Dimerization and Signaling in Corneal
Lymphangiogenes
National Eye Institute
Djalilian, Ali, MD
Notch Signaling in the Corneal Epithelium
National Eye Institute
Fortman, Jeffrey, DVM
Ophthalmic Animal Facility Grant
National Center for Research Resources
Grassi, Michael, MD
Genomic and Genetic Studies of Diabetic Retinopathy
National Eye Institute
Jain, Sandeep, MD
Keratocyte Role in Guidance of Corneal Nerves
National Eye Institute
Joslin, Charlotte, OD, PhD
Local Food Environments and Disparities in Ovarian Cancer Survival
National Institute on Minority Health and Health
Disparities, Center of Excellence Program
McAnany, Jason, PhD
Mechanisms Limiting Visual Performance in Retinal Degenerations
National Eye Institute
Pepperberg, David, PhD
Development Of Nanoscale Neuromodulating Platforms
National Eye Institute
Shahidi, Mahnaz, PhD
Retinal Image Quality In Retinal-Diseased Eyes
National Eye Institute
Shahidi, Mahnaz, PhD
Noninvasive Imaging of Chorioretinal Oxygen Tension
National Eye Institute
Shahidi, Mahnaz, PhD
Investigating Optical and Neural Causes of Vision Loss
Department of Veterans Affairs
Shukla, Deepak, PhD
Molecular Mechanism of HSV Entry and Spread
National Institute of Allergy and Infectious Diseases
Shukla, Deepak, PhD
Significance of Heparan Sulfate in HSV-1 Spread
National Institute of Allergy and Infectious Diseases
Vajaranant, Thasarat, MD
The Impact of Gender in Eye Diseases and Glaucoma
National Eye Institute Building Interdisciplinary
Research Careers in Women’s Health Program/
National Institute of Child Health and Human
Development/Office of Research on Women’s Health
Yue, Beatrice, PhD
Cellular Processing of Optineurin, the Product of a Glaucoma Gene
National Eye Institute
FOUNDATION SPONSORED RESEARCH
Aakalu, Vinay, MD
Development of a Prototype Temporal Fossa Glaucoma Shunt
Illinois Society for the Prevention of Blindness
Aakalu, Vinay, MD
Student Stipend
Midwest Eye-Banks
Azar, Dimitri, MD, MBA
Unrestricted Grant to Department
Research to Prevent Blindness
Chang, Robert, PhD
Collagen XVIII in Corneal Lymphangiogenesis
Midwest Eye-Banks
Chaudhary, Shweta, MD
Student Stipend
Midwest Eye-Banks
Djalilian, Ali, MD
Career Development Award
Research to Prevent Blindness
Farooq, Asim
Medical Student Eye Research Fellowship
Research to Prevent Blindness
Grassi, Michael, MD
Cellular Studies of Apoptosis in RP Using Small Molecule Screening
and RNA Interference
Foundation Fighting Blindness
Hou, Joshua, MD
Quantification of Adrenergic Receptor Subtypes in Human Muller
Muscle and Correlation with Phenylephrine Testing in the Evaluation
of Blepharoptosis
Illinois Society for the Prevention of Blindness
Hu, Jennifer, MD
Effect of Hemodialysis on Intraocular Pressure and Ocular Perfusion
Pressure
Illinois Society for the Prevention of Blindness
Jain, Sandeep, MD
Numerical and Experimental Study of Collagen Cross-linking
Treatment for Keratoconus
UIC Chancellor’s Discovery Fund for Multidisciplinary
Research
Jain, Sandeep, MD
Reinnervation After Corneal Surgery
Eye Bank Association of America
Jivrajka, Renu, MD
Early Detection of Functional Changes Using Microperimetry on
Patients with Subclinical Plaquenil Toxicity
Illinois Society for the Prevention of Blindness
Knepper, Paul, MD, PhD
Activation of Innate Immune Toll-4 Receptor in POAG
American Health Assistance Foundation
Pepperberg, David, PhD
Plasmonic Nano-antennas to Enhance Light Sensitivity of Retinal
Molecular Devices Designed for Vision Restoration
Doheny Eye Institute/Beckman Initiative for Macular
Degeneration
Shahidi, Mahnaz, PhD
Senior Scientific Investigator Award
Research to Prevent Blindness
Shukla, Deepak, PhD
Lew R. Wasserman Merit Award
Research to Prevent Blindness
Shukla, Deepak, PhD
Novel Peptides to Understand Herpetic Damage to Human
Trabecular Meshwork via Actin Rich Nanotubular Structures
The Glaucoma Foundation
Vajaranant, Thasarat, MD
Structural Testing in Advanced Glaucoma
American Glaucoma Society
Vajaranant, Thasarat, MD
Mentoring for the Advancement of Physician Scientists
American Glaucoma Society
Zerfoss-Oltra, Erica, MD
Correlation of Neurocognitive Function with Focal Macular Thinning
in Sickle Cell
Illinois Society for the Prevention of Blindness
17
Department of Ophthalmology & Visual Sciences | Treating the most serious and complicated ophthalmology cases for over 150 years
Tissue Donors Change Four Young
Lives Forever
The gift of sight gives patients a brighter future
Building on its success in treating young pediatric cornea
patients, the Illinois Eye and Ear Infirmary now offers a
Pediatric Cornea Section, launched in July 2010 with
the recruitment of Dr. Aisha Traish. She is joined by
Dr. Iris Kassem, the newest addition to the Pediatric
Ophthalmology and Adult Strabismus Service, headed by
Dr. Nathalie Azar. The stories offered here are a sample
of how young lives can be changed with the gift of cornea
transplants.
Catherine
was just a toddler when she began to have vision
problems. “She started running into things,” recalls her mother,
Crissie. “She couldn’t see the faces of other kids and didn’t even
recognize her own sister.” Catherine also had difficulty identifying
household objects, even though they were large and close by.
In September 2007, at the age of two years old, Catherine was
examined by Dr. Sandeep Jain, Director of UIC’s Corneal Neurobiology
Laboratory. Both of her corneas were cloudy, which explained her
impaired vision. “Based on a slit lamp biomicroscopy examination, we
diagnosed her as having Congenital Hereditary Endothelial Dystrophy
(CHED),” notes Dr. Jain. In this condition, the cornea absorbs water
due to the disease of the cells that line its back surface, causing the
cornea to swell up and lose its transparency, thus impairing vision.
“Given that Catherine’s impaired vision was now affecting her
development, the family consented to have us perform corneal
transplantation in both eyes,” says Dr. Jain. The right eye was operated
on in September 2008 and the left eye in January 2009.
Prior to surgery Catherine was barely able to see 20/200 during vision
testing, indicating that her vision efficiency was just 20%. At her most
recent visit she could see 20/30 with glasses, meaning that her vision
is now at 90%.
Today Catherine is an active five year old. “She’s doing great,” says
her mom Crissie. “She would have lost her sight without the organ/
tissue donation. It has made a 100% difference in what her life would
be. She’s a normal kid.”
Liliana first came to see Dr. Elmer Tu, Director of Cornea Service,
as a second opinion referral when she was just two weeks old. She
was born with Peters Anomaly, a disorder that causes central corneal
clouding, often with an attachment of the lens to the back of the
cornea. She was afflicted in both eyes and her parents had been told
that she needed immediate corneal transplants. Corneal transplants,
18
however, carry a high risk of rejection and failure in children.
“We were so happy with Dr. Tu,” exclaims Liliana’s mother, Kimberly.
“We had seen four other cornea surgeons. But we chose UIC and Dr.
Tu because it was the best fit for our family.”
At around six months, however, Liliana began to develop searching
movements of the eye, indicating that her visual progress was slowing.
Dr. Tu elected to remove a portion of the iris in her left eye in January
2006 to give her a new pupil in the area of clearest cornea. The iris in
her right eye was operated on in September 2009.
“At the age of four her right eye appeared to improve enough
anatomically that we started to consider corneal transplantation,”
notes Dr. Tu. After much consultation, a corneal transplant was
performed on Liliana in April 2010. “She has regained some function
in this eye over the past year and is able to make out colors and
images. Challenges still remain ahead for this eye, but so far she has
done well,” says Dr. Tu. Adds mom Kimberly, “Dr. Tu cannot believe
how great she is doing with the corneal transplant. Liliana can navigate
spaces very well and can tell an eye chart from 10 feet away. We’re
amazed at how well she is doing.”
Kimberly points out that she wasn’t a donor before Liliana’s
experience, and didn’t think much about it when getting her driver’s
license renewed. But she is a donor today. “Somebody helped my child
and hopefully someday I can help someone else. A donation gave my
daughter the opportunity to be able to see.”
Donovan
was also born with Peters Anomaly, which affected
both of his corneas, although the right eye was more severe.
“We waited for him to grow a little bit until he was two or three
months old, and then tried a rotational corneal transplant in the
right eye,” says Dr. Ali Djalilian, Director of the Stem Cell Research
Laboratory. “This is where we take his own cornea and rotate it so
the scar moves out of the center of the vision. We did this because we
knew his chance of success with a regular corneal transplant would
be very low.”
Unfortunately, the transplant did not work very long and within a
few months it failed. At this point Dr. Djalilian asked Dr. Jose de la
Cruz, Director of the Keratoprosthesis Program, to step in and he
elected to perform an artificial cornea transplant in Donovan’s right
eye when he was nine months old. This was very successful in helping
to restore vision in the right eye, but recently Donovan required a
second corneal transplant.
“Donovan is doing well,” says his mother Alicia. “He wouldn’t be able
to see without the donor tissue. When you’re a donor, it opens up so
many possibilities for families.”
Amaris developed what her pediatrician thought was a severe case
of pink eye. When a cataract was discovered in her right eye, Amaris’
parents took her to see Dr. Debra Goldstein, Director of UIC’s
Uveitis Service. Just shy of her fifth birthday, Amaris was diagnosed
with chronic uveitis, an inflammation that Dr. Golstein described as
being akin to “arthritis of the eye.” According to Amaris’ mother,
Crystal, Dr. Goldstein explained that the uveitis was treatable but not
curable, and would require Amaris to take several different types of
medication daily.
“Dr. Goldstein did all she could to keep Amaris’ eyesight,” recalls
Crystal. Dr. Goldstein did five of the six eye surgeries that Amaris has
undergone, with the first surgery at age five on her right eye.
In 2009 Amaris was diagnosed with glaucoma. Dr. Goldstein
referred Amaris to UIC’s Dr. Jacob Wilensky, Director of
Glaucoma Service, who performed a shunt
procedure in November 2009. During this
operation Amaris received donated
sclera (eye white) tissue. Until
Amaris’ parents were contacted
earlier this year to invite their
daughter to appear in the Illinois
Eye-Bank poster, they didn’t
realize that Amaris had been a
recipient of donor tissue.
Notes Crystal, “Amaris lost very little sight, but enough to be a voice
and an advocate for a great cause.”
Today Amaris is a busy 12-year-old girl who is on her school’s honor
roll and recently placed as a runner-up at the Miss Pre-Teen Chicago
pageant, snagging the Most Photogenic award. Crystal points out that
one day Amaris hopes to help someone else with an organ donation.
“It’s a blessing to have people who are willing to
donate,” says Crystal.
The efforts of the Illinois Eye Bank to encourage
organ and tissue donation were instrumental in the
lives of these four young people.
As a result of her positive
experience,
Amaris
has
decided to write a book to
spread the word about the
importance of organ/tissue
donation. She also reached
out to her donor’s family
with a poem titled The Gift of
Sight, which reads in part:
“With my eyes I can see
This most precious gift
your loved one gave
to me
They didn’t know me
from anyone else
But what they gave
to me values more
than wealth”
Young UIC patients
(clockwise from
top): Donovan,
Catherine, Liliana
and Amaris
19
Department of Ophthalmology & Visual Sciences | Treating the most serious and complicated ophthalmology cases for over 150 years
Clinical Investigations
and Trials
Contact Lens
Charlotte Joslin, OD, PhD
Corneal Refractive Power Post Refractive Surgery
Charlotte Joslin, OD, PhD
Local Food Environments and Disparities in Ovarian Cancer Survival
Ellen Shorter, OD; C. Joslin
Contact Lens Parameters in Keratoconus Patients at UIC, Illinois Eye and Ear Infirmary
Cornea
Ali Djalilian, MD
Changing the Fate of Skin Epithelial Cells Grown on Human Amniotic Membrane
Erica Oltra, MD
Assessment of Quality of Life in Patients with Tearing Disorders
Ellen Shorter, OD; J.de la Cruz;
C. Joslin
Longitudinal Evaluation of Boston Keratoprosthesis
Joel Sugar, MD
Compassionate Use of the Ophtec 311 Artificial Iris Lens Implant
Joel Sugar, MD
Cornea Donor Study - 10 year follow-up
Jose de la Cruz, MD
Evaluation, Management and Clinical Outcomes of Patients Who Underwent Keratoprosthesis for Visual Rehabilitation
Glaucoma
Thasarat Vajaranant, MD;
J. Wilensky; M. Lunde
Comparing the Effectiveness of Treatment Strategies for (Primary) Open-Angle Glaucoma
Thasarat Vajaranant, MD
Structural Assessment in Glaucoma
Thasarat Vajaranant, MD
Surgical Menopause and Risk for Premature Aging of the Optic Nerve and Glaucoma
Jacob Wilensky, MD
Clinical Experience with Transscleral Laser Cyclotherapy
Neuro-Ophthalmology
Heather Moss, MD, PhD
A Phase 1-Open-label, Dose Escalation Trial of QPI-1007 Delivered by Single Intravitreal Injection to Patients with Optic
Nerve Atrophy (Stratum I) and Acute Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION) (Stratum II)
Heather Moss, MD, PhD
Afferent Visual Function in Amyotrophic Lateral Sclerosis
Heather Moss, MD, PhD
Prospective Study to Determine the Proportion of Patients with Isolated Third, Fourth and Sixth Nerve Palsies of
Microvascular versus Non-Microvascular Etiology
Heather Moss, MD, PhD
Retrospective Evaluation of Optical Coherence Tomographic Imaging of Optic Nerve Head Evaluation
Oculoplastic Surgery
Vinay Aakalu, MD
Lacrimal and Accessory Lacrimal Tissue Gene Expression
Vinay Aakalu, MD
Ocular Trauma Score and Visual Acuity Outcomes in Ocular Paintball Injuries
Veena Kulchaiyawat, MD
Assessment of Visual Functioning and Quality of Life Before and After Ptosis Repair
Mark Krakauer, MD, DPhil; P. Setabutr
Oculoplastic Considerations in Keratoprosthesis Surgery
Mark Krakauer, MD, DPhil; P. Setabutr
Roof Pad Sculpting in Upper Blepharoplasty
Ramesh Singa, MD, DPhil; P. Setabutr
Elemental Peri-Orbital Tissue Gene Expression Analysis
Ramesh Singa, MD, DPhil; P. Setabutr
Eyelid and Oculoplastic Surgical Outcomes and Analysis
Pediatric Ophthalmology & Adult Strabismus
Iris Kassem, MD, PhD
20
Positional Changes in Preoperative Measurements for Pediatric Cataract Surgery
Filled rows indicate: Open patient enrollment | Red indicates a sponsored clinical trial.
To learn more about any of these investigations and trials, including how to refer patients, please call 312-996-6590.
Retina
Renu Jivrajka, MD;W. Mieler
Early Detection of Functional Changes Using Microperimetry in Patients with Subclinical Hydroxychloroquine (Plaquenil)
Toxicity
Jennifer Lim, MD;Y. Leiderman
F. Chau; L. Ulanski
Effect of Diabetes Education during Retinal Ophthalmology Visits on Diabetes Control (Protocol M)
Jennifer Lim, MD;Y. Leiderman
F. Chau; L. Ulanski
Intravitreal Ranibizumab or Triamcinolone Acetonide in Combination with Laser Photocoagulation for Diabetic Macular Edema
(Protocol I)
Jennifer Lim, MD;Y. Leiderman
F. Chau; L. Ulanski
A 1-Month, Multicenter, Observational Study to Evaluate the Degree of Ocular Inflammation Associated with Pars Plana
Vitrectomy
Jennifer Lim, MD;Y. Leiderman
F. Chau; L. Ulanski
A Double-Masked, Randomized, Active-Controlled Phase-3 Study of the Efficacy and Safety of Intravitreal Administration of
VEGF Trap-Eye in Patients with Diabetic Macular Edema
Jennifer Lim, MD; L. Ulanski
A Pilot Study in Individuals With Center Involved DME Undergoing Cataract Surgery (Protocol P)
Jennifer Lim, MD;Y. Leiderman
F. Chau; L. Ulanski
A Randomized, Double Masked, Controlled Phase 3 Study of the Efficacy, Safety and Tolerability of Repeated Intravitreal
Administration of VEGF Trap-Eye in Subjects with Macular Edema Secondary to Central Retinal Vein Occlusion (CRVO)
Jennifer Lim, MD
A Retrospective Case Series to Assess the Efficacy of Anti-VEGF Therapy in the Treatment of Macular Edema Secondary to
Retinal Vein Occlusion
Jennifer Lim, MD;Y. Leiderman
F. Chau; L. Ulanski
An Evaluation of Intravitreal Ranibizumab for Vitreous Hemorrhage Due to Proliferative Diabetic Retinopathy (Protocol N)
Jennifer Lim, MD; L. Ulanski
An Observational Study in Individuals with Diabetic Retinopathy Without Center-Involved DME Undergoing Cataract Surgery
(Protocol Q)
Jennifer Lim, MD;Y. Leiderman
F. Chau; L. Ulanski
An Open-Label Study of the Safety and Tolerability of Combining IBI-20089 (Triamcinolone Acetonide Intravitreal Injection)
When Used Adjunctively with Lucentis 0.5 mg Intravitreal Injection in Subjects with Subfoveal Neovascular Age-Related
Macular Degeneration
Jennifer Lim, MD; L. Ulanski
Comparison of Time Domain OCT and Spectral Domain OCT Retinal Thickness Measurement in Diabetic Macular Edema
(Protocol O)
Jennifer Lim, MD; L. Ulanski
Evaluation of Visual Acuity Measurements in Eyes with Diabetic Macular Edema
Jennifer Lim, MD; L. Ulanski
Intravitreal Ranibizumab or Triamcinolone Acetonide as Adjunctive Treatment To Panretinal Photocoagulation for Proliferative
Diabetic Retinopathy (Protocol J)
Jennifer Lim, MD; L. Ulanski
Maculopathy
Jennifer Lim, MD
Optical Coherence Tomographical Retinal Thickness Analysis of Sickle Cell Patients
Jennifer Lim, MD; L. Ulanski
Ranibizumab Therapy For Choroidal Neovascularization Associated With Angioid Streaks
Rohan Shah, MD; J. Lim
Retinal Degenerations and Their Effect on Retinal Thickness
Lawrence Ulanski, MD
A 3-Year, Phase 3, Multicenter, Masked, Randomized, Sham-Controlled Trial to Assess the Safety and Efficacy of 700 ug and 30
ug Dexamethasone Posterior Segment Drug Delivery System (DEX PS DDS) Applicator System in the Treatment of Patients
with Diabetic Macular Edema
Lawrence Ulanski, MD
Age-Related Eye Disease Study 2 (AREDS2): A Multi-Center, Randomized Trial of Lutein, Zeaxanthin, and Omega-3 LongChain Polysaturated Fatty Acids Docosahexaenoic Acid (DHA) and Eicosapentaenoic Acid (EPA) in Age-Related Macular
Degeneration
Lawrence Ulanski, MD
Home Vision Monitoring in AREDS2 for Progression to Neovascular AMD Using the ForeseeHome Device
Uveitis
Kelly Bui, MD; D. Goldstein;
J.M. Garcia-Gonzalez; S. Patel
Directed Conjunctival Biopsy in Ocular Sarcoidosis
Debra Goldstein, MD
Characteristics, Natural History and Treatment of Uveitic Diseases at the University of Illinois at Chicago, Uveitis Service
Debra Goldstein, MD
Long Term Follow-Up of Patients Who Participate in the Multi-Center Uveitis Steroid Treatment (MUST) Trial Follow-up Study
(FS)
Debra Goldstein, MD; S. Patel
Macular Configuration Predisposing to CME in Uveitis
Debra Goldstein, MD; S. Patel
Observation of Chronic Uveitis Longitudinally Across 4 Regions (OCULAR)
Debra Goldstein, MD
Phase III, Multinational, Multicenter, Randomized, Double-Masked Study Assessing the Safety and Efficacy of Intravitreal
Injections of DE-109 (three doses) for the Treatment of Active, Non-Infectious Uveitis of the Posterior Segment of the Eye
Debra Goldstein, MD;
A. Birnbaum; S. Patel
Simultaneous Bilateral Acute Anterior Uveitis: Prevalence, Etiology and Prognosis in a Retrospective Study
Debra Goldstein, MD; S. Patel
Standardization of Uveitis Nomenclature
21
Department of Ophthalmology & Visual Sciences | Treating the most serious and complicated ophthalmology cases for over 150 years
Honor Roll of Donors
$5,000-9,999
Arch W. Shaw Foundation
Dr. Jettie M. Burnett **
Edwin F. Schild Foundation
Mrs. Diane K. Henry *
Dr. Paul K. and Mrs. Ruth Morimoto **
Omega Surgery Centers, LLC
Mr. Steven B. Ross *
Don M. Smart, MD *
$2,500-4,999
Illinois Eye Fund Board. (L to R): Mr. Julian Berman, Dr. Samuel Cascio, Dr. Marilyn Miller,
Ms. Georgia Roulo, Dr. William Jackson Jones, Ms. Pat Wager, Dr. Dimitri Azar, and
Mr. Barry Carroll
Illinois Eye Fund
OFFICERS
CHAIR, Dimitri Azar, MD, MBA
VICE PRESIDENT, Samuel J. Cascio, DDS
TREASURER, Julian L. Berman
SECRETARY, Irene T. Schoenberg
MEMBERS
Barry J. Carroll
Gerald Fishman, MD
William Jackson Jones, DDS
Steven P. Koenig, MD
Barry Malkin
Frank I. Mendelblatt, MD
Marilyn T. Miller, MD
Steven B. Ross
Georgia Roulo
Sriram Sonty, MD
Van C. Stone
Joel Sugar, MD
Patricia Wager
Jacob Wilensky, MD
Emeritus
Harris Ripps, PhD, DSc
Diane Kraft Henry
EX-OFFICIO
Julie Daraska
ADVANCEMENT
David J. Eaton
22
$100,000+
Mr. Gerhard Cless *
Cless Family Foundation
Foundation Fighting Blindness
Hope for Vision
Research to Prevent Blindness, Inc.
$50,000-99,999
Alcon Laboratories, Inc.
$20,000-49,999
Glaucoma Foundation, Inc.
Mr. Gary R. Janko *
Midwest Eye-Banks and Transplantation
Center
Dr. John H. Panton *
Dr. Allen Putterman *
Rice Foundation
Dr. Howard H. and Mrs. Tena Tessler *
Mrs. Marie E. Wilkinson * †
$10,000-19,999
Solna A. Braude **
Braude Foundation
Dr. R. Mark and Mrs. Monica J.W. Hatfield *
Illinois Society for the Prevention of
Blindness
Dr. Pete A. and Mrs. Diane Greanias
Lagouros *
Dr. Dimitri T. and Dr. Nathalie F. Azar *
DuPage Eye Associates, SC DBA M. Raichand
MD, SC
DuPage Ophthalmology
Dr. Daniel B. Feller **
Ms. Anne C. Haffner in honor of
Dr. Paul Knepper **
Mr. Gerald and Mrs. Marsha Kaplan in
memory of Arnold M. Kaplan **
Ms. Elaine N. Kirk **
Dr. Steven P. and Mrs. Melinda Koenig **
Dr. Sao Cheng Liu **
Dr. Sao Jang Liu *
David M. Lubeck MD **
Harvey K. Minatoya MD **
Dr. John J. Moy **
Mr. Bradley A. Tisdahl in memory of
Mr. Barry Thomas McNamara **
Mr. John Veleris *
$1,500-2,499
Mr. Julian L. and Mrs. Joan S. Berman *
Mr. Barry J. and Mrs. Barbara P. Carroll *
The Carroll Foundation
Dr. David J. Fuerst and
Mrs. Marie M. Perrelli-Fuerst
Dr. Edward J. Goldman
IOP, Inc.
Dr. Paul A. Knepper
and Dr. Zibute Zaparackas *
Dr. John J. McGetrick **
Medical Eye Services, Ltd.
David D. Morimoto MD
Parent Petroleum Co. was recognized for its generous support of the Retina Chemical Genomics Lab, directed by Dr. Michael Grassi. Pictured (LtoR):
Mark Potaczek; Ysel Mancini, and Peter Mancini, all with Parent Petroleum Company; Dr. Dimitri Azar, Interim Dean of the UIC College of Medicine;
Dr. Grassi and Dr. Mahnaz Shahidi, Vice Chair for Research.
Josipa Paska
George R. Reiss MD
Dr. Harris and Mrs. Jeanne Ripps
Dr. William L. Schey **
Ms. Dorothy T. Tannenbaum
South Holland Lions Club
Strauss Foundation, Inc.
Mr. Robert B. and Mrs. Sheri B. Tisdahl in
memory of Ms. Roslyn Davis
UBS Matching Gift on behalf of
Mr. Bradley Tisdahl
$1,000-1,499
Dr. Daniel C. Alter
Dr. Phillip D. and Mrs.Vicki A. Alward **
Mr. Albert and Mrs. Doreen Barsky
Batavia Lions Club
Dr. Harit K. Bhatt and Ms. Anamika Das
Mrs. Andrea Bromberg
Dr. Steven B. Cohen
Dr. Anne L. Coleman
Mr. Serge D. De Bustros
in honor of Dr. Dimitri T. Azar
Dr. Deepak P. and
Mrs. Deepak P. Edward*
Ms. Anita S. Gerber and Dr. Joel Sugar
Dr. Morton F. and Mrs. Myrna Goldberg *
Dr. Sherwin Isenberg
Lee M. Jampol, MD
Brian C. Joondeph, MD
Jennifer I. Lim, MD
Dr. Irwin Menachof
Mr. William J. and Mrs. Jean M. O’Neill
Mrs. Deloras A. Pemberton
The Philip and Myn Rootberg Foundation
Mr. Javier Rubinstein
Dr.Veeral S. Sheth
Mr. Gregory L. and Mrs. Carlene G. Smith*
$500-999
Dr. Alan J. and Mrs. Jennifer K. Axelrod
Norman P. Blair, MD
Dr. Samuel J. Cascio *
Ms. Mary E. Davidson
Dr. Jesse M. and Dr. Libbie B. De Leon
Globetrotters Government Sector, LLC
Nancy A. Hamming MD
Dr. Alice O. and Mr. James F. Keane
Dr. Timothy T. and Mrs. Kay McMahon
Mrs. Jenifer Mason Robbins
Kathleen M. Scarpulla MD
Mr. LeRoy and Mrs. Albina Schalansky
Mr. Ira J. and Mrs. Beverly W. Schulman
Dr. Joanne Shen
Synthes
Dr. Mark O. M. and Mrs. Petrina C. Tso
Prof. Elmer Y. Tu
Dr. Thasarat S.Vajaranant
Ms. Patricia S. Wager *
Dr. Robert S. and Mrs. Shifri A. Weinberg
Dr. Robert D. Wertz
Ms. Chai S. Wilensky
Dr. Jacob T. Wilensky
$250-499
Dr. Lawrence I. and Mrs. Patricia Chapman
Dr. Robert A. Copeland
Jill A. Foster MD
Robert E. Gorsich MD
Dr. Marc F. Greenberg
Mr. Donald L. Leone
Dr. Miriam T. Schteingart Light
Dr. Diosdado T. Lim
Dr. Frank I. and
Mrs. Katherine Mendelblatt
Dr. Floyd G. Miller
Ashok R. Penmatcha MD
Mr. William D. Perkins
Ms. Marcia Pevsner
Dr. Jose S. Pulido and Dr. Colleen A. Howe *
Mr. James T. and Mrs. Karen C. Reid
Dr. Alan V. and Mrs. Linda K. Spigelman
Elvira Teel Trust †
Mr. Georg G. Toft
Enrique Garcia-Valenzuela MD
up to $250
Mr. Shankarnaray Adapathya
Ms. Doris Anderson in memory of
The Reverend David D. Hancock
Mr. Charles L. Barsky
Mr. Gregory B. Beggs
Abdhish R. Bhavsar, MD and
Mary A. Bhavsar
Mr. John J. and Mrs. Phyllis A. Bierdz
23
Department of Ophthalmology & Visual Sciences | Treating the most serious and complicated ophthalmology cases for over 150 years
up to $250 (continued)
Dr. Rebekah A. Braslow
Mrs. Marie J. Bugajski
Mr. Anthony Buttitta
Ms. Cynthia Caplin
in memory of Ms. Barbara McDonald
Dr. Michael E. Carroll
Mr. Ronald L. and Mrs. Lucy C. Chamberlain in
memory of The Reverend David D. Hancock
Mr. Franklin A. and Mrs. Doralu Chanen
Ms. Gladys A. Charleston in memory of Ms.
Deidre Redington
Chicago Cornea Consultants, Ltd.
Dr. David M. and Mrs. Barbara L. Cohen
Mr. L. Park and Mrs. Sharlene M. Davis
Dr. Naomi L. Ellenhorn-Davis
Discover Financial Services matching gift on
behalf of Mr. Charles Barsky
Dr. Mohammed El Mallah
Randy J. Epstein, MD and Linda S. Katz
Bruce D. Fick, MD
Mr. Leo and Mrs. Lillian E. Floros
Mr. Roger L. and Mrs. Susan E. Frick in
memory of The Reverend David D. Hancock
Joseph B. Garber, MD
Bernardino Garcia, MD and Robyn M. Garcia
Dr. Bruce R. and
Mrs. Moyra Dunne Garretson
Ms. Mary C. Gates
in memory of Mr. James Zembron
Mr. Michael L. Gates
in memory of Mr. James Zembron
Miss Elden Genitis
Ms. Anita S. Gerber and Dr. Joel Sugar in
memory of Mr. Stellan C. Aker
Mrs. Sandra K. and Mr. Glen Gibbons in
memory of The Reverend David D. Hancock
Mrs. Opal and Mr. Kenneth R. Glasco in
memory of The Reverend David D. Hancock
The Honorable Sidney J. Goldstein
Ms. Charlotte R. Goldwater
Mr. Chris E. and Mrs. M. K. Goolsby in
memory of The Reverend David D. Hancock
Mrs. Sylvia E. Greenberg
Pierre Guibor, MD *
Mrs. Dorothy Hadrava in memory of
Mr. James Zembron
Mr. Dean and Mrs. Nila Hemming in memory
of The Reverend David D. Hancock
Charles C. Ho, MD
Dr. Paul I. and Mrs. Cindy Jo Homer
Mr. Richard A. and Mrs. Mary E. Howell
Indian Camp Baptist Church in memory of
The Reverend David D. Hancock
The Insurance House in memory of
The Reverend David D. Hancock
Donald S. Jacobs, MD
Mrs. Beverly and Mr. J. C. Jones in memory of
The Reverend David D. Hancock
Ronald A. Kalayta, MD
Dr. Richard V. and Mrs. Zoe Kaufman
Mr. William G. Keenan in memory of
The Reverend David D. Hancock
Ms. Jane Kelly in memory of
Mr. James Zembron
Mrs. Paula L. and Mr. Kenneth W. Kelly in
memory of The Reverend David D. Hancock
Ms. Kate T. Kestnbaum *
Mrs. Evelyn Kibler
Ms. Arlene M. Knapp
Mrs. Iwanna A. and Mr. Lukasz Krynicki in
memory of Mr. James Zembron
Mr. T. and Mrs. T. Kuzniarek in memory of
Mr. James Zembron
Dr. Charlton Rex and Mrs. Janet M. Latta
Mrs. Ale B. and Dr. Eligijus P. Lelis
Ms. Carolyn M. Leonard in memory of
The Reverend David D. Hancock
Mrs. Patricia M. Livingston
Mr. Tim and Mrs. Jennifer L. Lovell in memory
of Mr. James Zembron
Dr. Paul Arthur Mahlberg
Ms. Helorna N. McFall
Mr. Donald E. McMahon
in memory of Mr. James Zembron
Mrs. Mildred R. Monsen
Dr. Marcus and Mrs. Sue Muallem
Mr. Donald E. and Mrs. Elisabeth A. Murphy
in memory of Mr. James Zembron
Mrs. Genie Murphy
Mrs. Arlene Musil
Ms. Jeanne Nelson in memory of
The Reverend David D. Hancock
Mr. Anthony J. and Mrs. Anthony J. Onesto
Ms. Lynn Orschel
Ms. Linda Osowski in memory of Mr. James
Zembron
Mr. Todd R. Osterbur
Mr. Richard Palandech
Dr. Robert W. and Mrs. Marika M. Panton
Mrs. Sally L. Pope *
Mr. Anthony L. Rainaldi
Prof. John T. and Ms. Sarah D. Ramsey
Mr. James E. Rathmann in memory of
Mrs. Elsie Rathmann
Ms. Jane W. Ravid
Mr. Marvin Rogan in memory of
Mrs.Laura L. Rogan
Dr. Alfred A. Rosenbloom Jr. and
Mrs. Sarah R. Rosenbloom
Mr. David G. Rosenfeld
Mr. Warner A. Rosenthal
Mr. Thomas and Ms. Sharon S. Schaefer in
memory of Mr. James Zembron
Mrs. Gloria B. Schall
Joel A. Schulman, MD
Mr. Richard L. and Mrs. Judith L. Schultz
Mr. Stanley L. Schwartz
Mr. Lee S. Simon
Mrs. Debra W. Sinay *
Ms. Barbara S. Spielman
Hugo R. Steinitz, MD
Mr. Daniel S. Sugar
Dr. Karen D. Sumers
Mr. Terry A. and Mrs. Rosemary Summers in
memory of The Reverend David D. Hancock
John B. Thompson, MD
Mr. Joe Till and Mrs. Janet Gonek in memory
of Mr. James Zembron
Ms. Elissa Tisdahl
Mr. Robert B. and Mrs. Sheri B. Tisdahl in
honor of Dr. Howard Tessler
Ms. Charlene McSparin Troutman in memory
of The Reverend David D. Hancock
Dr. Dana O. Troyer
Ms. Cynthia Buehring-Upchurch in memory of
Leslie Julia Baber
Samuel J.Vainisi, DVM
Ms. Deborah Walens and Mr. John C.
McCrosky in memory of Mr. James Zembron
Mr. Fred and Mrs. Janice Weissman
Mr. Steve and Mrs. Bonnie Wheeler in
memory of The Reverend David D. Hancock
Martha J. Willi, MD
Mr. J. L. and Mrs. Orline Williams† in memory
of The Reverend David D. Hancock
Dr. Sherrie D. Williams
Mrs. Maxine D. and Mr. Jerry L. Williamson in
memory of The Reverend David D. Hancock
Willow Springs Lioness Club
Mr. Michael J. and Mrs. Kathleen A. Worrall
Dr. Beatrice Y.Yue
Mr. Tony Zamora
Mr. Charles D. and Mrs. Debra Zis
* President’s Council
** Chancellor’s Circle
24
M
In memory of our good and caring friend,
arie E. Wilkinson
Marie E. Wilkinson, a generous donor to the Illinois Eye Fund since
1988 when she made her initial gift in memory of her late husband,
Herbert Wilkinson, passed away this past June. She was 100 years
old. Herbert passed away in June 1988. Marie and Herbert Wilkinson were partners in life in every way,
including their philanthropy. Herbert was a longtime executive with
Abbott Laboratories, where he began his career in 1930. He was
president and director of Abbot Laboratories. He retired in 1971 and
then served as president of the Board of the Clara Abbott Foundation,
and as vice president of the Abbott Laboratories Fund. Marie and Herbert met in Cincinnati and moved to Chicago when he
joined Abbott. They settled in Lake Forest in 1957 and had three
children, Carol Keenan of Chicago, Janet W. (Thomas M.) Leopold of
Winnetka, and the late Herbert S. Wilkinson, Jr. Marie also leaves
two grandchildren and five great-grandchildren. Herbert Wilkinson’s association with the Department of
Ophthalmology and Visual Sciences started in the late 1980s as a
patient. His philanthropy started soon afterwards, and he became
deeply committed to the Department and its research and patient care
programs. Upon his death, Marie continued Herbert’s devotion to
the Department for another 25 years through continued philanthropy
supporting a variety of research programs and equipment purchases.
of her husband. These
gifts were instrumental in helping the
researchers develop new treatments and cures for eye disease and
blindness. The positive impact of Mr. and Mrs. Wilkinson’s generosity is felt by patients now and in the future who will benefit from this
research. Their legacy of helping lives on.”
Among the research programs that received support from Mrs.
Wilkinson’s generous donations to the Illinois Eye Fund are the
Photoreceptor Research Laboratory directed by David Pepperberg,
PhD, the Ocular Virology Research Laboratory directed by Deepak
Shukla, PhD, and the Retinal Circulation and Metabolism Laboratory
directed by Norman Blair, MD Most recently, research funding has
been provided to one of the Department’s young clinician scientists:
Soledad Cortina, MD. Dr. Cortina’s research focuses on the study of
corneal nerves and possible treatments that will speed corneal nerve
recovery. In addition, Marie’s gifts made possible the acquisition of
a state-of-the-art instrument to rapidly measure the concentration
of proteins and other biomolecules in a variety of basic science
experiments. FortéBio’s new Octet® RED96 System will foster new
vision science discoveries. Marie Wilkinson trained as a nurse and did part of her medical training
in Appalachia. She was passionate about helping others and making
a difference. As an avid gardener, she loved to see things grow and
develop. Her desire to help others was demonstrated also by her
volunteer activities with several organizations including her church,
the First Presbyterian Church in Lake Forest, and the Boarder Babies
program in Chicago.
“These are just a few examples of the important vision research activity
that has been greatly aided by Marie Wilkinson’s generosity,” stated
Dr. Dimitri Azar, Interim Dean of the College of Medicine, B.A. Field
Endowed Chair of Ophthalmologic Research, and Professor and Head
of the Department of Ophthalmology and Visual Sciences. “Mr. and
Mrs. Wilkinson understood that research in vision and ophthalmology
would improve the quality of care and quality of life for everyone
suffering from vision loss or blindness, today and for generations to
come. We are deeply indebted to them.” According to Patricia Wager, former executive director of development at the University of Illinois Medical Center who worked with
Mrs. Wilkinson since the late 1980s, “Helping people was a central
part of Mrs. Wilkinson’s life. She demonstrated this wonderful quality through her contributions to the Department of Ophthalmology
and Visual Sciences to support eye research for 25 years in memory
The Illinois Eye Fund provides support for research, education
and patient care in the Department of Ophthalmology and Visual
Sciences. The Department leads in the diagnosis, management,
and treatment of the most serious and complicated ophthalmologic
cases. To make a gift, go to www.uic.edu/com/eye/WaysToGive or call
312-996-6590. 25
Department
of Ophthalmology
& Visual Sciences
the most serious and complicated ophthalmology cases for over 150 years
| Treating
Department
of Ophthalmology
& Visual
Sciences
Renovations & Innovations
New cutting-edge equipment and renovated spaces benefit doctors and patients
area, the Glaucoma Service now features seven rooms
equipped with the new M&S Vision Testing System.
This high-tech alternative to chart projectors is a
computerized vision testing system that features a wide
variety of charts, contrast sensitivity and multimedia
functions. In addition, the Glaucoma Service now has
two independent visual field testing rooms, a renovated
technician suite and a new dedicated conference room.
“This renovation definitely benefits us all,” says
Thasarat S. Vajaranant, MD, Assistant Professor of
Ophthalmology and Director of Glaucoma Service. “It
allows us to work more efficiently to deliver the best
care. I personally received many positive comments
from our patients.”
Dr. Thasarat S. Vajaranant, Director of Glaucoma Service
RENOVATIONS
A series of extensive renovations at the Illinois Eye and Ear Infirmary
has resulted in much-improved treatment spaces for both patients
and doctors. Renovations completed in 2011 include welcoming new
reception areas, the addition of high-tech diagnostic equipment, and
patient amenities such as comfortable new furniture and flat screen
TVs in waiting areas. According to Agustin Lopez-Scala, Assistant to
the Head of Ophthalmology and Visual Sciences, patient care areas
for the Cornea, Contact Lens and Glaucoma Services, and the new
Comprehensive Ophthalmology Faculty Practice, all underwent
renovation.
The biggest expansion occurred in the Glaucoma Service, which went
from 10 to 15 rooms and relocated from the second to the third
floor of the Infirmary building. Besides a new reception and waiting
26
Other renovation highlights include the addition of
four exams rooms in the Cornea Service. Each room is
equipped with an M&S Vision Testing System. Contact
Lens Service has relocated and has three new rooms,
along with a special contact lens trial room outfitted
with contact lenses and diagnostic equipment. The
Comprehensive Ophthalmology Faculty Practice
expanded from three to six exam rooms, plus a
dedicated testing area. Each new room is equipped with
the M&S Vision Testing System. Comprehensive Ophthalmology also
has a new reception and waiting area.
“The additional space has allowed us to increase volume while
maintaining excellent care,” notes Pete Setabutr, MD, Assistant
Professor of Ophthalmology and Director of Oculoplastic Surgery.
“The improvements in the waiting area provide a relaxed and
comfortable area for our patients.”
Big plans for 2012 include the entire renovation of the Pediatric
Ophthalmology & Adult Strabismus Service, located on the second
floor of the Infirmary building. The project includes a new reception
and waiting area, eight exam rooms, one visual testing room, and four
other clinical and administrative rooms. Also, six rooms on the second
floor of the Infirmary building will be converted to physicians’ offices.
These new spaces will be home to doctors who have been hired within
the past two years and have not had permanent offices.
INNOVATIONS
Exciting new cutting-edge equipment was installed in 2011, with more
scheduled to be in place in the coming year. In 2011, the department
acquired a new Trabectome® unit for the Glaucoma Service. This
FDA-approved surgical device allows for minimally invasive treatment
of glaucoma that decreases pressure in the eye and stabilizes vision.
The outpatient Trabectome® surgical procedure can lower pressure
into the mid-teens and reduce the patient’s reliance on glaucoma
medications, without subjecting the eye to the risks of a more invasive
trabeculectomy.
The department is currently in the process of acquiring a femtosecond
laser system for use in cataract surgery. This is breakthrough
technology originally approved for refractive surgery, including
LASIK procedures. However, the FDA has now approved the use
of the system to include “cuts” in the cornea, including vertical and
lamellar cuts. The possibilities for use now include, but are not limited
to, femtosecond keratoplasty, astigmatic keratoplasty, and Intacs for
keratoconus.
The femtosecond laser differs from the traditional method of refractive
surgery in a number of ways, using a near infrared light to create
precise subsurface cuts. Traditionally, in refractive surgery ultraviolet
light sources, such as the excimer laser, have been used for precise
surface cuts on the cornea. These light sources were dependent on
tissue properties to absorb the light. The femtosecond laser works
independently of light tissue absorption, so photodisruption of
deeper tissues is possible and the patient’s corneal anatomy (such
as steepness, flatness or thickness of the cornea) does not interfere
with the cuts. This leads to a more uniform treatment. In addition,
femtosecond pulses are very short, of subpicosecond duration, which
allows lower energy levels and aids in precision, decreasing collateral
damage. The femtosecond laser system is expected to be ready to use
by Ophthalmology’s surgeons, fellows and residents by June 2012.
Dr. Elmer Tu, Director of Cornea Service
27
INTERNATIONAL
contributions
Two Brazilian professors join
the research faculty
Dr. Norma Allemann and Dr. Wallace Chamon, both on the
Department of Ophthalmology faculty of the Federal University of São
Paulo, Brazil, are Visiting Professors for the 2011-2012 academic year.
Dr. Allemann’s research and clinical expertise includes ultrasonography
and optical coherence tomography for anatomic evaluation of ocular
structures in different clinical and surgical situations. She is an expert in
and teaches ultrasound biomicroscopy, anterior segment ultrasound,
anterior segment optical coherence tomography, ultrasound and
optical biometry, and ocular ultrasound, as well as refractive surgery
techniques.
and Excimer Laser Ablations; and Corneal Nerve Regeneration and
Crosslinking, with Dr. Azar, Dr. Jain and Dr. de la Cruz. While at
UIC, Dr. Chamon hopes “to learn from Dr. Azar how to academically
address new advances and new technologies in ophthalmology,” as well
as learn methods to improve teamwork in research. He also plans to
secure an official agreement between UIC and the Federal University
of São Paulo to establish a residency exchange program between
ophthalmology departments that would begin in 2012.
Dr. Allemann trained at the Federal University of São Paulo where she
earned a PhD and a Masters in Medicine in ophthalmology following her
medical training, ophthalmology residency and two fellowships, one in
external diseases and cornea and another in ocular ultrasound and
refractive surgery. She also completed a research fellowship in 1992
under Dr. Jackson Coleman at Cornell University Medical College.
Since 1998 she has acted as vice president of the American Society of
Ophthalmic Ultrasound, a forum for the exchange of ideas and scientific
discussion of ophthalmic ultrasound system design, microimaging,
experimental applications, and the clinical practice of ophthalmic
ultrasonography. She is also president and former scientific director
of the Brazilian Society of Ecography in Ophthalmology. She will act as
president for the 2012 SIDUO Meeting (Societas Internationalis Pro
Diagnostica Ultrasonica in Ophthalmologia) in December 2012 that
will be held in São Paulo, Brazil.
Fellows and Residents
While at UIC, Dr. Allemann will be collaborating with the Azar research
group on the Total Eye Transplantation research project. Dr. Allemann
is also working with the Retina Service to expand and improve our
ultrasound clinical services. At the Cornea Service she will collaborate
with projects in imaging keratoprosthesis. Dr. Allemann notes that she
will participate in the Illinois Eye Review, as well as help by submitting
papers originating from her research at UIC.
Dr. Chamon practices, teaches and conducts research in the areas
of restoring corneal transparency, myopia and public health, and
therapeutics of refractive errors. During his visit, he will collaborate
with Dr. Dimitri Azar, Dr. Pier Cristoforo Giulianotti and Dr. Enrico
Benedetti on the Robotics in Ophthalmic Surgery project. He will
also work on the Corneal Biomechanics and Finite Element Modeling
project with Dr. Azar, Dr. Sandeep Jain, Dr. Jose de la Cruz and Dr.
Craig Foster, Assistant Professor of UIC’s Civil & Materials Engineering
Department. Additional projects include Corneal Nerve Regeneration
Dr. Norma Allemann
Dr. Chamon trained at the University of São Paulo in the city of
Ribeirão Preto (medical training and ophthalmology residency),
and earned a PhD and Masters in Medicine in ophthalmology at the
Federal University of São Paulo following a fellowship in external
diseases, cornea and refractive surgery. He completed a research
fellowship in 1992 at Johns Hopkins University: Dr. Walter Stark
served as his preceptor. Dr. Chamon is the current Coordinator of the
Scientific Committee and former secretary of the Brazilian Council
of Ophthalmology. He also is a scientific referee for Investigative
Ophthalmology and Visual Science and, most recently, for the British
Journal of Ophthalmology. He serves on the editorial board of the
Journal of Refractive Surgery, and is editor-in-chief of the Brazilian
Archives of Ophthalmology.
“Dr. Chamon and Dr. Allemann will contribute significantly to our
research and clinical programs,” Dr. Azar states. “To continue as a
top-ranked ophthalmology department we must continually renew
our thinking and programs. The contributions of international leaders
like Drs. Allemann and Chamon are critical to this process.”
Dr. Wallace Chamon
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CREDITS
Lisa Birmingham, Designer
Contributors: Margaret Chervinko • Julie Daraska • Marcia Niec • Anna Castro-Malek • Laurie Walker
Photography: Lisa Birmingham • Cathy Carroll • Joshua Clark • Roberta Dupuis-Devlin • Mark Janowicz
www.IllinoisEyeAndEarInfirmary.com
UPDATE 2011
VISION
O n e
NOVEMBER 10-13, 2012
American Academy of Ophthalmology Meeting—in Chicago
September 14, 2012
UIC Oculoplastics Symposium
june 29, 2012
Alumni Day
May 16, 2012
Spring Glaucoma Symposium
APRIL 20-24, 2012
The American Society of Cataract and Refractive
Surgery Symposium & Congress— in Chicago
March 30, 2012
UIC Retina Symposium
March 17-23, 2012
5th Annual Illinois Eye Review
UPCOMINg Symposia
1855 West Taylor Street
Chicago, IL 60612
COLLEGE OF MEDICINE
and Visual Sciences
UIC Department of Ophthalmology
UNIVERSITY OF ILLINOIS
AT CHICAGO