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ORIGINAL RESEARCH ARTICLE International Journal of Current Medical And Applied Sciences. [IJCMAAS] Volume: 13, Issue: 2, January -2017, pp: 93-96. A Retrospective Study on Demography & Clinical Profile of Patients with Aluminium Phosphide Poisoning in Kanyakumari Government Medical college Hospital,Tamilnadu, India. Prince Sreekumar Pius1, Bhamini Prakash2 &Thanalakshmi Jayaram3 1-Associate Professor, 2-Assistant Professor, 3-Postgraduate, Department of General Medicine, Kanyakumari Government Medical College Hospital, Kanyakumari, Tamilnadu, India. --------------------------------------------------------------------------------------------------------------------------------------Abstract: Background: Aluminium phosphide is used as pesticide, rodenticide, fumigant for storage of food and grains. In Kanyakumari district this poison is mainly used as a pesticide to control the pests which attack tender nuts resulting in immature nut fall. Aluminium phosphide is a easily available poison and relatively cheap. There is a steady state increase in occurrence of this poisoning in the recent years. It has high mortality rate because no specific antitode or treatment is available. In Kanyakumari Government medical college, we treated the patients with coconut oil Instillation through NG tube, Crystalloids, Inotropes, Intravenous Magnesium sulphate infusion. Methods: Our study was on cases admitted with Aluminium phosphide poisoning during the year 2011-2015 admitted in Kanyakumari government medical college hospital. Patients presenting with multiple poison consumption and those with previous history of heart disease were excluded from the study. A detailed collection of data regarding the demography, number of tablets consumed. The time of presentation after consumption, detailed clinical assessment, routine blood investigations and a 12 lead ECG reports were collected. Results: The Male to female ratio is 4:1. Incidence is more in age group 20-50 years. Common in Rural areas than Urban areas. Shock and unrecordable BP are most common clinical signs. Mortality rate was 70%. The most common ECG changes were Sinus tachycardia, ST,T changes, Ventricular tachycardia. Patients presenting earlier and who have taken the tablet mixed in liquids had better prognosis. The mean Lethal dose is 4.5 grams. Conclusion: Aluminium phosphide is a dreadful poison causing high mortality . Poisoning is common in middle age males and Rural populations. The prognosis is favorable if the poison is mixed with liquid and then taken. Key Words: Aluminium phosphide, Incidence, Mortality, ECG changes. --------------------------------------------------------------------------------------------------------------------------------------------------------------------Address for correspondence: Dr. Prince Sreekumar Pius, Access this Article Online Associate Professor, Department of Medicine Website: Kanyakumari Government Medical College Hospital Kanyakumari, Tamilnadu India. www.ijcmaas.com Email; [email protected] [email protected] How to cite this article: Prince Sreekumar Pius, Bhamini Prakash & Thanalakshmi Jayaram: A Retrospective Study on Demography & Clinical Profile of Patients with Aluminium Phoshpide Poisoning in Kanyakumari Government Medical Hospital,Tamilnadu, India: International Journal of current Medical and Applied sciences; 2017, 13(2),93-96. . . . . . . . . Subject: Medical Sciences Quick Response Code