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Small-Scale and Niche Market Pork Production Conference BASICS OF A HERD HEALTH PROGRAM FOR SMALL-SCALE AND NICHE MARKET SWINE PRODUCTION Jeremy S. Pittman, D.V.M., Diplomate ABVP Murphy-Brown L.L.C.-North Division Waverly, Virginia Introduction Swine health is one of the largest factors impacting profitable pork production. Inversely, veterinary care (veterinary visits, medications, vaccination) is one of the lowest input costs of a swine operation. So how does that work? Significant losses associated with disease can be seen from decreased feed efficiency (measured as pounds of feed required for each pound of pork sold), decreased productivity (as with total pigs born, born alive, pigs weaned per sow, etc), decreased growth performance (lower average daily gains, longer time to market, longer time to maturity), increased morbidity (sickness) and mortality (dead pigs), decreased revenue (sort loss, culls versus markets), increased medication costs and disposal costs. If swine are managed properly and a good health program is in place, the cost of medications and vaccinations can be significantly reduced. In addition, veterinary visits can be less frequent or on an as-needed basis (although I’m sure we can debate what “as-needed” means). While there are significant differences in how swine may be raised or housed and which diseases that might be commonly dealt with, the fundamentals of health programs for swine are the same for small-scale and niche producers as they are for large producers. The objective of this paper and accompanying presentation is to provide the audience with a basic understanding of how disease occurs, what factors influence disease, and what are the basics to developing an effective and efficient heard health program. Important concepts To fully understand and appreciate heard health, one must have at least a basic knowledge of the mechanisms of disease and why it occurs. Below are some concepts that are basic building blocks of veterinary medicine. 1. The Health - Disease Relationship – The maintenance of health in an animal or population (and thus disease) is determined by the interaction of three main categories: 1) the Host, 2) the Pathogen and 3) the Environment. This is commonly called the disease triangle, with each point representing one aspect. The idea is that there are interactions between each corner of the triangle and this interaction is where disease occurs or is prevented. For example; interactions between Host and Pathogen could be vaccination, exposure and immunity. Interactions between Host and Environment could be chilling effects, wet or dry surfaces, and stocking density. Interactions between Environment and Pathogen could be sanitation, disinfection or humidity. Each interaction is a potential point of control or failure in the maintenance of health. 21 Small-Scale and Niche Market Pork Production Conference Another common way to think of it is a balance (Figure 1), with the host’s disease pressures on one side and their supporting immunity on the other. If more “weight” is put on the disease side of the scale (exposure, poor sanitation, stress), then the host experiences disease. If on the other side we support the host’s immune system (vaccinations, treatments, clean environment) then the host remains healthy. Host Health Disease Immunity Factors Pathogen Factors Host Pathogen Environment Figure 1. Visual representation of the Health-Disease relationship. The Disease Triangle showing the interaction between Host, Pathogen and Environment. The Disease scale showing the balance between Disease and Host Immunity. 2. Infectious and non-infectious disease – Disease by definition is an abnormal condition of the body. This is important because not all disease is caused by a pathogen (virus, bacteria, etc) that can be targeted, treated or protected against. Non-infectious causes of disease in swine are very common and therefore must be differentiated from infectious causes. Nutrient deficiencies, toxicities, stress and incorrect management can lead to disease in pigs and none of these can be treated with an antibiotic or vaccinated against. 3. Bacteria, viruses, parasites and fungi – Most all infectious disease is caused by one of the listed types of organisms. Swine by nature are commonly exposed to all types of these organisms, with many normally inhabiting the surrounding environment or even the intestinal, respiratory, reproductive tracts and skin of swine and never cause disease. Some of these organisms are or can become pathogens, and thus cause disease. Factors that commonly allow these organisms to become pathogens are: poor sanitation, decreased immunity of the host, overwhelming exposure or challenge, changes in the organism, presence of other pathogens, presence of other risk factors (stress, mixing, chilling, etc) and response of the host to the pathogen. Table 1. Strategies for control and treatment by pathogen type Pathogen Biosecurity Management Vaccination Bacteria + + +/Virus + + + Parasite + + Fungi + + - 22 Treatment + - (supportive care) + + Small-Scale and Niche Market Pork Production Conference 4. Exposure, infection and disease – There is a difference in these three terms when discussing disease. Exposure means that pigs have come in contact with the specific organism in question, but not that infection or disease has or will occur. Infection is the process by which the organism colonizes in the pigs and established a “foot-hold” in the animal, but again may or may not cause disease (or clinical disease). Disease is the actual process that develops from an infection that leads to an abnormal condition. 5. Vaccination – Vaccination is basically a “controlled infection”. Using a variety of methods or products pigs are given part or all of an organism whereby their immune system can respond and develop immunity to that organism. The key here is that it is the pig’s immune system that is the protective factor. Vaccines are not 100% protective. The purpose of vaccination is to reduce the severity of clinical disease, duration of disease and shedding/transmission to other animals. Animals may still get sick if they are exposed to the pathogen even if they have been vaccinated, however the hope is that the impact of disease is much less. Not all pathogens can be vaccinated against, not all vaccines are effective and some even cause disease. Understanding the goals of vaccination and the expectations of vaccination are important when formulating a herd health plan. 6. Medication, treatment, therapy – Use of medications in swine are for the treatment of sick animals, the prevention of disease or the improvement of feed utilization. The most important thing to understand with medicines is that they are specific to the types of pathogens they treat. Most antibiotics treat only bacteria, others only parasites and others only fungi. In addition, there are specific classes of antibiotics that work for specific types of bacteria. Therefore, you need to have a pretty good idea what you might be treating for. There are no antibiotics for viral infections. Therapy for viral infections is usually supportive care (reduce fever, provide electrolytes, etc) at best. Failure to understand this concept commonly results in the products not working. In addition, an animal’s response to treatment is highly dependent on the animal’s immune status, ability to fight of disease and early and correct treatment of the disease. Commonly failure of an antibiotic to work is related to one or more of the following: a. Treatment started too late b. Disease occurred too rapidly c. Disease is not treatable by antibiotics (i.e., viral or non-infectious) d. Treatment is not used for complete duration e. The pig’s immune system not working properly (i.e., PRRS, stress) f. Selected the wrong antibiotic i. wrong drug for the bug ii. drug can’t get to the site of infection g. Drug given by the wrong route h. Drug given at wrong dose h. Bacteria resistant to antibiotic i. Drug no longer active (expired, storage issues, contamination, incompatible mixing) j. Incorrect diagnosis (based on clinical signs OR diagnostic samples) 7. Disease as a result of the host – One very important concept for veterinarians is that most of the aspects of a disease that allow us to characterize the disease (clinical signs, lesions, diagnostic tests) is a direct result of the host’s response to the pathogen(s) involved. Often the 23 Small-Scale and Niche Market Pork Production Conference most severe damage and resultant clinical signs are from how the animal’s immune system responds to the infection. 8. Breeding herd versus growing herd – One very significant aspect of the swine industry is the management of two separate herds, often within one herd. This is important because disease challenge and health strategies can be significantly different (and often in conflict) between the two herds. Depending on the particular types of disease you are trying to control will dictate what and how you use specific products or programs. One very common example is the vaccination of sows prior to farrowing. Often the goal in vaccinating the sow pre-farrow is not to protect her, but rather provide protection through antibodies in the colostrum/milk to her piglets when born. This can change the dynamics of immunity (and thus disease) in the growing herd, and in some cases make it more difficult to vaccinate growing pigs successfully. 9. Over the counter versus Prescription antibiotics – These are the two main types of antibiotics for use in swine. Over-the-counter (OTC) drugs can be purchased at agricultural stores or through catalogues without direction from a veterinarian. The limitation on using these products is that the user must follow the directions of the label including, mixing instructions, species and stage of life of animal, duration of use and condition/disease treated and meat withdrawl period. Using OTC drugs in a manner different from the label requires a veterinary prescription. Veterinary prescription requires a valid veterinary-client-patient relationship which itself has a set of requirements. Prescription antibiotics are provided on the order of a veterinarian. Veterinarians have the authority to use some products in an off-label manner, such as drugs not labeled for that species, changing the dose and duration of treatment and for indications/diseases not on the label. This is important because there are not products labeled for every disease or pathogen that is commonly dealt with. Key Fundamentals of Health Program I. Biosecurity Biosecurity means the “protection of life”, and is a commonly used catch-all term for health management protocols in many areas of veterinary medicine, but especially the swine industry. In general, biosecurity is the collection of practices and rules that a farm puts in place to reduce the risk of disease in the herd. This can be external biosecurity, which are protocols to prevent entry of a disease into the herd that was not there previously, or internal biosecurity which prevent disease transmission between groups within the same herd. While the term “biosecurity” is relatively new, the concept is definitely not. As you will see in the below list of common biosecurity aspects, each concept has been utilized for a long time in swine production. However, there are a few key points in each one that can usually be revisited or re-evaluated in every herd. These are not necessarily listed in order of importance (risk), but the top 3 would be key in most all farming systems. Given the specifics of the farm, there may be others that pose a higher risk and should be addressed. One method of ranking would be to consider the aspects that happen the most in a week/month and address those first, followed by those that are less frequent. 24 Small-Scale and Niche Market Pork Production Conference 1. Animals entering the farm/herd – There is no better way to give a pig a disease, than to introduce it to other pigs with that disease. Animals entering a herd are the #1 cause of disease entry into a herd. While this is commonly considered to be new animals, usually new/replacement breeding stock (gilts and boars), it is not limited to that. Animals entering the herd could be new wean or feeder pigs purchased from another farm or stockyard, borrowing the neighbors stud boar or allowing the neighbor to bring his sow over to use your boar. Animal entry should also be considered when animals leave the farm and then return, such as with livestock shows or fairs, as they can contract disease from other pigs at these venues. a. Note on Purchasing New Animals – If you are purchasing animals for the herd, you should ask specific questions as to the health status of their herd of origin. Working with a veterinarian can help to identify specific diseases you should be concerned with. b. Note on Quarantine/Isolation – An area of the farm, separate from the herd, should be set up for animals entering or returning to the herd. A common period of isolation is 30 days, which allows adequate time for development of clinical signs or serological testing for diseases of concern. 2. Semen entering the farm/herd – This focuses strictly on semen for artificial insemination. Intact boars used for breeding are considered in item 1. Semen can be a major source of disease to a breeding herd if the health status of the stud or origin farm is not controlled. Diseases such as Porcine Reproductive and Respiratory Syndrome (PRRS), Leptospirosis, Brucellosis, Tuberculosis, Porcine Circovirus Type 2 (PCV2), Pseudorabies (PRV) and Parvovirus (PPV) have been shown to be transmissible in semen. In addition, bacterial contamination of semen can cause significant issues with conception rates and vulvar discharges. 3. Sanitation – Sanitation is important between group of pigs (finishing barn or paddock) or stages of life (i.e., farrowing facility) to reduce the transmission of pathogens through feces, urine and dust/dander. Sanitation is also important during the growing or holding period of the animals. Routine removal of organic material (feces, urine, old feed, etc) helps to decrease the pathogen load in the environment. Sanitation of barns or facilities is a multi-step process with emphasis on the order. The ultimate goal is to remove all potential infectious material form the facility. a. Step 1) Removal of visible organic material (scrape, washing, etc.) b. Step 2) Soak/washing with a detergent and high pressure. Hot/warm water > cold water; pressure washer > high pressure hose c. Step 3) Rinse cleaned area d. Step 4) Allow adequate drying time. This is the most important step. e. Step 5) Applying disinfectant. Depending on your farm’s pathogens, different disinfectants should be used (See Appendix). Sunlight is a great disinfectant! f. Step 6) Allow adequate contact time for disinfectant. g. Step 7) Rinse away excess disinfectant and allow time to dry. h. Step 8) Inspect quality of washing between each step. 25 Small-Scale and Niche Market Pork Production Conference In situations where facilities cannot be completely cleaned (dirt lots, paddocks, etc), all attempts to clean the majority of fecal material or allow rotation of area should be attempted within reason. 4. Disease status – Knowing what diseases your herd already has and does not have is an important part of any herd health management plan. Knowing what you have is important in selecting management protocols, proper vaccination protocols and timing of those vaccinations, selection of the proper antibiotics to be using and an expectation of results. Knowing what diseases you do not have is important in screening the purchase of animals, recognizing new diseases and sale of animals. There are usually several diseases that farms are or should be concerned with, depending on the purpose of the farm and facility designs. Routine testing of the herd to screen for some key diseases is important and should be done at least annually, but also when animals enter the herd or when changes in the health status dictate an investigation. Often blood, fecal and skin samples are adequate for many diseases we are concerned with. At times, tissues from sick or dead pigs can provide valuable information on the status of a herd. a. Note on Observation – Animals should be observed daily at a minimum. Each animal is observed for changes in behavior or health status. Observing when behavior (isolation, lethargy, not eating) or health status changes (coughing, scours, fever) allows more rapid response to a developing problem. Quick response to problems can mitigate the impact of the challenge. b. Note on Records – One area that is usually lacking on smaller herds is record keeping of the farm, including but not limited to; animal identification, history of performance, treatment and vaccination history, etc. Daily records of environment (hi/lo temps, humidity), observations (sick pigs, number not eating, mortality, etc.) and treatments (# treatments, duration, product given, amount given) can be valuable for veterinarians when attempting to determine changes in health status and response to therapy. 5. Vaccination Protocols – “An ounce of prevention is worth a pound of cure.” ~ Benjamin Franklin The use of vaccines, as stated above, is to minimize the severity of clinical disease and boost the pig’s immune system so that it can fight diseases better. Vaccine questions often asked are, “What should I vaccinate for?”, “Should I vaccinate for Disease X?”, “That vaccine is expensive, can I just wait and see?” These are not easy questions to answer for a broad group of farms, because it is dependent on each farm’s health status, farm type (breeding herd, growing herd, both, etc.), farm location (locality to other farms, area of the country, etc.) and facilities (outdoor, indoor, etc.). There are some basic diseases that should be considered for vaccination on most any farm. It is strongly recommended that you consult with a veterinarian for specifics on vaccines and vaccination programs that optimize your farm’s health program. 26 Small-Scale and Niche Market Pork Production Conference Breeding herd – a. PPV, Leptospirosis, Erysipelas (PLE) (usually as a single combined vaccine) are diseases that cause significant reproductive and/or systemic disease in breeding herds. This vaccine is given twice before their first breeding and once prior to each subsequent breeding event (usually 2 times per year). This would include boars twice yearly. b. E. coli and Clostridium are bacteria that cause significant diarrhea in newly born pigs and are very common on all types of herds. Vaccination of gilts and sows prior to farrowing (usually twice for gilts at 6 and 3 weeks before farrowing and sows once at 3 weeks prior) increases antibody in the colostrum and milk and helps to protect the pigs from these bacteria. There are multiple types of E. coli and Clostridium so a vaccine must be specific to these subtypes, as there is no cross-protection. c. Other vaccines that could be used depending on the status of your herd would be Atrophic Rhinitis (Pasturella and Bordetella), Mycoplasma hyopneumoniae, PCV Type 2, Ileitis (Lawsonia), PRRS and Swine Influenza. Growing pig herd – a. PLE– Commonly given in Midwestern herds, but would depend on the pressure of the disease in the herd and vaccine strategy of the breeding herd. The timing of this vaccine is dependent on sow herd vaccination protocol. b. Ileitis – Depends on the status of your growing herd. This is a live oral vaccine and needs to be given by mouth or through water system. This vaccine is usually given after 6 weeks of age. c. Mycoplasma hyopneumoniae and PCV Type 2 – These two pathogens can cause significant growth retardation and/or mortality in growing pigs. Often the vaccines are found in combination or a mixture, and are given at a similar time (3 and 6 weeks of age). d. PRRS – there is much debate on the benefit of this vaccine in smaller and less challenged herds. The product is usually given to pigs at 3 weeks of age. 6. Treatment Protocols – Most farms will need to have some protocol for treatment when pigs get sick or prevention of predictable diseases. A common preventative treatment is the use of injectable iron at processing to prevent baby piglet anemia and use of injectable penicillin or topical iodine at castration to prevent wound infections. These are examples of routine treatment protocols. There is also a need for treatment of sick pigs that may occur over time. A reminder that not all drugs are the same and do not work for all types of pathogens. Drugs that are more broad spectrum (i.e., are effective for several types of pathogens) are usually more expensive. Other drugs that are more specific are usually less expensive, but require better knowledge of the pathogen involved. This is likened to the “shotgun” versus “rifle” approach. The most advanced treatment protocols involve the recognition of basic clinical signs and selection of particular antibiotics related to the most common pathogens associated with those clinical signs. This can be costly and confusing, but results in a higher likelihood of success. Less advanced treatment protocols may utilize a single antibiotic for all types of clinical signs, with maybe a secondary drug if the animals 27 Small-Scale and Niche Market Pork Production Conference do not respond to the first. This program would be more attractive from a cost savings and simplicity standpoint. a. Hospital Pens – If animals are grouped together, it is usually a good idea to separate or segregate sick animals. This is usually done with a “hospital” or “critical care” pen, where isolation from the other animals and additional care (e.g., heat source) can be provided. This also helps to slow the transmission of disease to other animals. 7. Emergency Response “Chance favors the prepared mind.” ~ Louis Pasteur What will you do when things go wrong? Having an emergency response plan is an important part of a health program. Knowing how to respond or who to contact in the event of an emergency can save you time and money, mitigate potential losses and calm some of the frustrations. Have an emergency contact list for your farm with Police, Fire, Rescue, Power/Utility company, feed company and Veterinarian. Know how to recognize and what your “First Aid” for common issues would be. For example, if you have an outbreak of severe diarrhea in a group of finishing pigs what medication would you treat with? Again, this is a broad question and should be discussed with your veterinarian with specifics to your farm. If you needed to run medication through the water, do you have it on farm or would you need to go get it? Where would you get it from? 8. Transportation – Trucks, trailers and livestock haulers should be considered as moving barns, and thus cleaned with the same thoughts as discussed in “Sanitation” above. Trailers should be washed and disinfected between loads. If you borrow or contract trailers for movement or shipping of animals, care should be taken to ensure a clean unit. Also, a clear understanding of the previous “haul’s” health status should be considered. This is more of a risk when there is frequent use of the equipment. The most significant risks of a trailer are: 1) the animals and thus manure/urine from a previous load, and 2) contact of the trailer to livestock facilities or yards (i.e., packing plants, cull/buying stations, other farms). 9. Equipment and Supplies – Equipment can be contaminated with manure, urine, blood, saliva and other materials. Under ideal conditions, such as short time, cold and damp weather, pathogens can survive on these materials. Equipment, supplies, and tools brought onto a farm, used between farms or barns, can transmit disease. These are often called “fomites” in the literature. For example, borrowing your neighbors front end loader that he also uses to bury dead animals is a significant risk. Other risks are tools used on other farms that are brought into your farm. It is not that these pieces of equipment can’t be brought in, just that you should have some protocol for cleaning and disinfection of the materials. Visible inspection that they are free of organic material and disinfection should suffice for most situations. Extensive protocols for higher health herds also exist. 28 Small-Scale and Niche Market Pork Production Conference 10. People and clothes – People, clothes and boots are very common items that come in and out of farms daily. Many commercial sow farms have adopted a showerin/shower-out policy, whereby employees and visitors take showers before entering the farm and wear farm provided clothes and boots. This provides a specific barrier to these risks. While the necessity of showering is debatable, changing of one’s clothes and boots and at a minimum washing arms and hands has been shown to be effective in preventing disease between groups of pigs. Many pig companies and farms have developed a concept of “downtime” for people and visitors. Downtime is an established amount of nights or days that one must be away from pigs, pig material and/or other livestock before entering a farm. Usually this is one night, but can be as many as 5 nights depending on the health statuses of the destination farm and recently visited farms. 11. Pest Control (rodents, birds, cats & dogs, cockroaches, feral hogs) – There are several diseases that are transmissible to people through pig meat (Trichinellosis, Toxoplasmosis, Salmonella). These diseases are a significant focus of state and federal programs, as well as a main underlying reason why development of alternative methods of raising pigs was pursued. Most of these diseases have significant risk factors that involve rodents, cats and feral pigs. In addition, there are diseases that can be transmitted to pigs from other animals (PRV, Brucellosis, Tuberculosis, Leptospirosis, Rabies). Significant efforts should be made to eliminate or minimize the access of these other animals to swine. Baiting programs, trapping, reduction of habitat, reduction of feed sources, deterrents, etc., are all strategies for pest control. 12. Mortality Management – One area that is not often considered, but is obvious once brought to light is how farms manage their mortality disposal. Removal of dead animals should be done as soon as the animal is found. Several options exist for disposal depending on your local regulations and services: burial, composting, incineration, rendering. If mortality is kept on-site, the risk is less, however can still be a source of contamination of equipment (see Equipment and Supplies), attractant for wildlife and pests (buzzards, wild dogs, etc.). The pig(s) died from something right? Rendering is a much larger risk to a farm, due to the fact that the rendering unit likely travels to multiple sites on a route. If this is the scenario, steps should be put into place to minimize the risk of tracking disease back into the farm. In most situations, disposing of mortality should be the last activity of the working day on the farm. 13. Support Services – While not as much of a risk as the above items, support services (propane delivery, mail carriers, meter readers, etc.) can be a source of transmission to a farm if they visit other farms, especially if on a route in the area. Minimizing contact between these services and the farm should be attempted. 14. Security – General farm security is always important for prevention of theft or destruction of property. These events can also present a risk of disease transmission. 29 Small-Scale and Niche Market Pork Production Conference II. Disease Recognition and Diagnosis An important step in managing health is to have a basic understanding of what is normal and what manifestation of abnormal look like. This section will provide a general overview of the main types of disease commonly seen in swine. 1. Reproductive – Reproductive failure is a general term for any disease that affects estrus, fertility, conception, pregnancy, abortions, early farrowing, embryo survival, total born, born alive, stillborn pigs, mummified fetuses, weak born pigs or irregular returns to estrus. Diagnosis of reproductive failure is a very complicated process, due to the fact that many causes can be non-infectious in nature. Diagnosis of reproductive failure can be very challenging when an obvious cause of disease is not found. Common reproductive diseases are: a. PRRS b. Parvovirus c. Leptospirosis d. Swine Influenza e. PCV2 f. PLE g. PRV h. Brucellosis i. Bacterial infections 2. Enteric – Diseases of the intestinal tract usually result in diarrhea (scours) and are commonly grouped by age. This is primarily due to changes in immunity, the function of the gut as pigs age, and diet composition. Losses due to enteric diseases come from decreased feed conversion, decreased average daily gains, increased variability in growth, dehydration and death. Common enteric disease by age group are: a. Breeding Adults i. Salmonella ii. Ileitis iii. Gastric Ulcers iv. Brachyspira colitis v. Internal Parasites (whipworms, roundworms) vi. Transmissible gastroenteritis (TGE) b. Suckling piglets (0 - 21 days of age) i. E. coli ii. Clostridium (Type A, C and difficile) iii. Rotavirus iv. TGE v. Coccidiosis vi. Salmonella vii. PRRS viii. Management: Drafts, chilling, poor milk quality c. Nursery pigs (3 - 10 weeks age) i. E. coli 30 Small-Scale and Niche Market Pork Production Conference ii. Rotavirus iii. Coccidiosis iv. Salmonella v. TGE d. Grow-Finish pigs i. Ileitis ii. Salmonella iii. Brachyspira colitis iv. Internal Parasites (whipworms, roundworms) v. Feed ingredients vi. Gastric Ulcers 3. Respiratory – Diseases of the lungs, upper airways and nose are significant causes of economic loss in the swine industry. Commonly growing herds experience a syndrome called Porcine Respiratory Disease Complex (PRDC), whereby several pathogens (a virus and a bacteria, or two, or three …) interact to cause disease together, making the symptoms much more severe and difficult to treat. Respiratory disease can be localized to the upper respiratory tract as with Atrophic Rhinitis, exist in the airspace in the lung (Mycoplasma pneumonia, Swine Influenza), exist within the lung tissue (PRRS, Pasturella) or exist in the space between the lungs and the ribcage (Actinobacillus Pleuropneumonia [APP], Haemophilus parasuis). Respiratory disease can be seen as increased sneezing, coughing, deep hacking coughing, “barking” or “thumping” in which pigs take short strong breaths using their abdominal muscles. Common respiratory diseases are: a. PRRS b. Swine Influenza c. PRV d. Mycoplasma pneumonia e. Pasturella f. Bordetella g. Atrophic Rhinitis (Pasturella and Bordetella together) h. Laveral migration of parasites through lungs i. Streptococcus suis j. Haemophilus parasuis k. Salmonella cholerasuis l. APP/actinobacillus suis m. Ammonia, humidity and/or dust levels 4. Systemic – Systemic disease is where pathogens cause a generalized inflammatory state throughout the entire body. This is commonly characterized by high fever, lethargy, cold and/or purplish extremities (ears, nose, feet, tail, belly). Systemic disease can also manifest in many ways depending on which organ or body system is infected: brain = neurologic, joints = lameness, lung = respiratory, etc. Often these diseases occur so quickly that unless recognized and treated immediately, pigs will die from fever and/or dehydration. Common systemic diseases are: a. PRRS b. Pseudorabies 31 Small-Scale and Niche Market Pork Production Conference c. d. e. f. g. Streptococcus suis Haemophilus parasuis Salmonella APP/ actinobacillus suis E. coli 5. Neurological – Diseases that affect the brain or spinal cord are common in swine. These diseases usually require immediate attention or death will soon follow. Signs of neurologic disease are “paddling” in which the pigs lay on their side with head tilted back and move their feet like they are swimming, walking in circles, head raised up and back, uncommon eye movements, incoordination when walking and “dog sitting”. Common diseases that cause neurological signs are: a. Streptococcus suis b. Haemophilus parasuis c. E. coli (Edema disease) d. Water deprivation or Salt Toxicity e. PRV f. PRRS g. Arsenic toxicity h. Abcesses from severe tail biting i. Lightning strike 6. Skin – Disease that affect the skin of swine are either from an external disease process (mange, ringworm, “greasy pig”, sunburn) or internal process (Erysipelas, PCV2). This distinction is important as treatments are often determined to be topical or injectable in nature. Common causes of skin disease in swine are: a. Mange b. Lice c. Greasy Pig (Staph hyicus) d. Ringworm e. Pseudo-ringworm f. PCV2 (also known as Porcine Dermatitis and Nephropathy Syndrome [PDNS]) g. Erysipelas (“Diamond Skin Disease”) h. Sunburn 32 Small-Scale and Niche Market Pork Production Conference References and Resources Iowa Pork Industry Center Niche Pork Production Handbook: www.ipic.iastate.edu/publications.html Local and national extension offices Virginia: www.pubs.ext.vt.edu/category/swine.html North Carolina: www.cals.ncsu.edu/an_sci/extension/swine/Default.htm Iowa: www.ipic.iastate.edu/ Ohio: porkinfo.osu.edu/ National Organizations National Pork Board: www.pork.org National Pork Producers Council: www.nppc.org Websites The Pig Site: www.thepigsite.com US Pork Center of Excellence: www.usporkcenter.org Pork Niche Market Working Group: www.leopold.iastate.edu/pork-niche-marketworking-group Magazines Pork Magazine: www.porknetwork.com National Hog Farmer: nationalhogfarmer.com Books Pork Industry Handbook -Available for purchase at: usporkcenter.org/ResourcesAndOpportunities/512/PorkIndustryHandbook.aspx Handbook of Pig Medicine by Peter Jackson and Peter Cockcroft (approx $125) Pig Ailments Recognition and Treatment by Mark White (approx $25) Raising Healthy Pigs on Small Farms by D. Earle Goodman (approx $15) 33 Small-Scale and Niche Market Pork Production Conference Table 2. Common injectable drugs used in swine and key label indications. Drug* Dose Label Condition Prescription† Comment Penicillin 1 cc per 100 Erysipelas No Often used at 1cc/20 lbs. lbs. for general disease issues Ampicillin Depends on Respiratory, Urinary, Yes Not labeled for swine mix Skin Oxytetracycline 1 ml per 22 Pasturella pneumonia No Different concentrations lbs. (200 mg exist bottle) Tylosin 1 ml per 12.5 Mycoplasma arthritis, No Different concentrations lbs. (50 mg Pasturella pneumonia, exist bottle); 1 ml Erysipelas, Dysentery per 50 lbs. Can be used for (200 mg Clostridial scours with bottle) prescription Lincomycin 1 ml per 5 lbs. Infectious Arthritis No Different concentrations (25 mg/ml (lameness) exist bottle); 1 ml per 20 lbs. (100 mg/ml bottle); 1 ml per 60 lbs. (300 mg/ml bottle) Ceftiofur 1 ml per 30 Strep suis, Yes Different formulations in lbs. (Naxcel, H parasuis, Excede, Naxcel, Excenel Excenel) Pasturella, APP, +/and generics Salmonella 1 ml per 44 cholerasuis lbs. (Excede) Gentamicin 1 ml per pig Colibacillosis (E. No Limited to use in coli) suckling pigs Tulathromycin 1 ml per 88 Mycoplasma Yes lbs. pneumonia, H parasuis, Pasturella, APP Ivermectin 1 ml per 75 Roundworms, No Variable efficacy on lbs. lungworms, lice and internal parasites mange *CAUTION: Antibiotic withdrawal should always be followed for any product in swine intended for food. Withdrawals depend highly on manner in which the product is used and market(s) animals are sold into. Consult with your veterinarian on required withdrawal times for products you use. †Assumes product is used per label. Off-label use of any product requires a prescription. 34